Shinichi Nozaki

Summary

Affiliation: Kanazawa University
Country: Japan

Publications

  1. ncbi request reprint Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor
    Shinichi Nozaki
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Oral Oncol 41:971-7. 2005
  2. ncbi request reprint Targeting urokinase-type plasminogen activator and its receptor for cancer therapy
    Shinichi Nozaki
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Japan
    Anticancer Drugs 17:1109-17. 2006
  3. doi request reprint Expression of urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor and maspin in oral squamous cell carcinoma: Association with mode of invasion and clinicopathological factors
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Oncol Rep 26:1555-60. 2011
  4. ncbi request reprint Copper efflux transporter (ATP7B) contributes to the acquisition of cisplatin-resistance in human oral squamous cell lines
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Ishikawa 920 8641, Japan
    Oncol Rep 18:987-91. 2007
  5. doi request reprint Loss of maspin is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Oral Pathol Med 38:535-9. 2009
  6. doi request reprint Loss of claudin-7 is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920 8641, Japan
    Oncol Rep 29:445-50. 2013
  7. ncbi request reprint Correlation of basic fibroblast growth factor expression with the invasion and the prognosis of oral squamous cell carcinoma
    Takashi Hase
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    J Oral Pathol Med 35:136-9. 2006
  8. ncbi request reprint Activity of biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in a human breast cancer orthotopic model
    Shinichi Nozaki
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Exp Metastasis 20:407-12. 2003
  9. ncbi request reprint Multicenter phase I trial of induction chemotherapy with docetaxel and nedaplatin for oral squamous cell carcinoma
    Hiroshi Kurita
    Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto 390 8621, Japan
    Oral Oncol 40:1000-6. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor
    Shinichi Nozaki
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Oral Oncol 41:971-7. 2005
    ..These results suggest that overexpression of uPAR increases the invasiveness and metastasis of OSC-19 cells, and that uPAR is a promising therapeutic target for regulation of progression of oral cancer...
  2. ncbi request reprint Targeting urokinase-type plasminogen activator and its receptor for cancer therapy
    Shinichi Nozaki
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Japan
    Anticancer Drugs 17:1109-17. 2006
    ..In particular, preclinical mouse model studies that used human tumor xenografts are reviewed...
  3. doi request reprint Expression of urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor and maspin in oral squamous cell carcinoma: Association with mode of invasion and clinicopathological factors
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Oncol Rep 26:1555-60. 2011
    ..These results indicate that uPA, uPAR and maspin expression patterns may be useful markers for evaluating the clinical course or prognosis of OSCC patients...
  4. ncbi request reprint Copper efflux transporter (ATP7B) contributes to the acquisition of cisplatin-resistance in human oral squamous cell lines
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Ishikawa 920 8641, Japan
    Oncol Rep 18:987-91. 2007
    ..We conclude that ATP7B is correlated with the acquisition of CDDP resistance more closely than either CTR1 or ATP7A. ATP7B may be a key determinant in the acquired resistance to CDDP in OSCC...
  5. doi request reprint Loss of maspin is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    J Oral Pathol Med 38:535-9. 2009
    ..In this study, we investigated the interrelationship between clinicopathologic findings and maspin expression in oral squamous cell carcinoma (OSCC)...
  6. doi request reprint Loss of claudin-7 is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma
    Kunio Yoshizawa
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920 8641, Japan
    Oncol Rep 29:445-50. 2013
    ..These results suggest that loss of claudin-7 expression is associated closely with invasion and lymph metastasis and is an unfavorable prognostic factor in patients with OSCC...
  7. ncbi request reprint Correlation of basic fibroblast growth factor expression with the invasion and the prognosis of oral squamous cell carcinoma
    Takashi Hase
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    J Oral Pathol Med 35:136-9. 2006
    ....
  8. ncbi request reprint Activity of biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in a human breast cancer orthotopic model
    Shinichi Nozaki
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Exp Metastasis 20:407-12. 2003
    ..These results suggest that the novel MMP inhibitor BAY 12-9566 maybe a useful and safe oral treatment for breast cancer, adjunctive to surgery...
  9. ncbi request reprint Multicenter phase I trial of induction chemotherapy with docetaxel and nedaplatin for oral squamous cell carcinoma
    Hiroshi Kurita
    Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, 3 1 1, Asahi, Matsumoto 390 8621, Japan
    Oral Oncol 40:1000-6. 2004
    ..This combination chemotherapy is active and well tolerated and warrants a phase II study. We recommended 60 mg/m(2) DOC and 100 mg/m(2) CDGP for phase II study...