Affiliation: Kanazawa University
Rahmatika D, Kuroda N, Min Z, Nainu F, Nagaosa K, Nakanishi Y. Inhibitory effects of viral infection on cancer development. Virology. 2018;528:48-53 pubmed publisher
..These inhibitory effects were not observed when growth-defective virus was used to infect animals. These results indicate that productive viral infections repress tumorigenesis in Drosophila. ..
Kong Q, Nakai Y, Kuroda N, Shiratsuchi A, Nagaosa K, Nakanishi Y. Peptidoglycan recognition protein-triggered induction of Escherichia coli gene in Drosophila melanogaster. J Biochem. 2015;157:507-17 pubmed publisher
..These results suggest that a host immune receptor triggers a change of gene expression in bacteria simultaneously with their recognition and induction of immune responses. ..
Nainu F, Tanaka Y, Shiratsuchi A, Nakanishi Y. Protection of Insects against Viral Infection by Apoptosis-Dependent Phagocytosis. J Immunol. 2015;195:5696-706 pubmed publisher
..Collectively, our study demonstrates that the apoptosis-dependent, phosphatidylserine-mediated phagocytosis of virus-infected cells plays an important role in innate immune responses against viral infection in Drosophila. ..
Nonaka S, Ando Y, Kanetani T, Hoshi C, Nakai Y, Nainu F, et al
. Signaling pathway for phagocyte priming upon encounter with apoptotic cells. J Biol Chem. 2017;292:8059-8072 pubmed publisher
..This phenomenon most likely ensures the phagocytic elimination of apoptotic cells by stimulated phagocytes and is thus considered as a mechanism to prime phagocytes in innate immunity. ..