Research Topics
| I IshikawaSummaryAffiliation: Kanazawa Medical University Country: Japan Publications
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Detail Information
Publications
Cystic renal cell carcinoma, suspected because of lack of regression of renal cysts after renal transplantation in a dialysis patient with acquired renal cystic diseaseIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Uchinada, Kahoku, Ishikawa 920 0293, Japan
Clin Exp Nephrol 7:81-4. 2003..No case of cystic RCC occurring in a dialysis patient has previously been reported. Cystic RCC should be suspected in a cystic mass in the original kidney which does not regress after successful renal transplantation...- Effect of oral adsorbent (AST-120) on renal function, acquired renal cysts and aortic calcification in rats with adriamycin nephropathyIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Uchinada, Kahoku, Ichikawa 920 0293, Japan
Nephron 92:399-406. 2002..The effect of oral adsorbent, AST-120, on the experimental renal disease induced by adriamycin, uninephrectomy and high protein diet proposed as a model of acquired cystic disease of the kidney was investigated... - Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise in patients with or without renal hypouricemiaIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University Uchinada, Ishikawa, Japan
Nephron 91:559-70. 2002..One hundred and eighteen cases of ALPE were collected from the literature, and half of the cases were found to display renal hypouricemia... 
Long-term natural history of acquired cystic disease of the kidneyIsao Ishikawa
Department of Internal Medicine, Division of Nephrology, Asanogawa General Hospital, Kanazawa, Japan
Ther Apher Dial 14:409-16. 2010..Kidney enlargement due to ACDK reached a plateau after 21.1 years of hemodialysis in the male patients. Partial regression of severe ACDK may occur naturally after long-term hemodialysis without renal transplantation...- Present status of renal cell carcinoma in dialysis patients in Japan: questionnaire study in 2002Isao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Ishikawa, Japan
Nephron Clin Pract 97:c11-6. 2004..To determine the incidence and recent trends of renal cell carcinoma (RCC) in dialysis patients, a nationwide investigation was performed in Japan... - Proteomic analysis of serum, outflow dialysate and adsorbed protein onto dialysis membranes (polysulfone and pmma) during hemodialysis treatment using SELDI-TOF-MSIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Dialysis Center, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan
Am J Nephrol 26:372-80. 2006..Alterations in the profiling of peptides and proteins in the serum, outflow dialysate and adsorbed protein on the dialysis membrane were investigated... - Imaging of acquired cystic disease-associated renal cell carcinoma by contrast-enhanced ultrasonography with perflubutane microbubbles and positron emission tomography-computed tomographyIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Asanogawa General Hospital, 83 KosakaNaka, Kanazawa, Ishikawa 920 8621, Japan
Clin Exp Nephrol 15:136-40. 2011..The pathological subtype of RCC in this patient was acquired cystic disease-associated RCC (ACD-associated RCC), which has been newly defined by Tickoo et al. (Am J Surg Pathol 30:141-153, 2006)... - Proteomic analysis of rat plasma by SELDI-TOF-MS under the condition of prevention of progressive adriamycin nephropathy using oral adsorbent AST-120Isao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Uchinada, Kahoku, Ishikawa, Japan
Nephron Physiol 103:p125-30. 2006.... - Twenty-year follow-up of acquired renal cystic diseaseI Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan
Clin Nephrol 59:153-9. 2003..This is a report of the 20-year follow-up... - Hemolytic uremic syndrome associated with influenza A virus infection in an adult renal allograft recipient: case report and review of the literatureM Asaka
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Ishikawa, Japan
Nephron 84:258-66. 2000..The prognosis of posttransplant HUS differs according to the cause. The advent of ciclosporin has improved the graft survival rate and mortality of patients with rejection-induced HUS... - Acute glomerulonephritis after human parvovirus B19 infectionT Nakazawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Japan
Am J Kidney Dis 35:E31. 2000..No control group subjects contained HPB19 DNA as determined by PCR. This circumstantial evidence indicates that HPB19 infection may be one of the causes of acute glomerulonephritis in normal individuals... - Diagnostic potential of tear proteomic patterns in Sjögren's syndromeNaohisa Tomosugi
Division of Nephrology, Department of Internal Medicine, Knanazawa Medical University, 920 0265 Ishikawa, Japan
J Proteome Res 4:820-5. 2005..These findings support the potential of proteomic pattern technology in tear fluids as the noninvasive diagnostic test for primary SS... - Renal cell carcinoma detected by screening shows better patient survival than that detected following symptoms in dialysis patientsIsao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Kahoku, Ishikawa 920 0293, Japan
Ther Apher Dial 8:468-73. 2004..Especially, there was a large effect of screening for renal cell carcinoma in the young dialysis patients... - Detection of serum hepcidin in renal failure and inflammation by using ProteinChip SystemNaohisa Tomosugi
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Kahoku, Ishikawa 920 0293, Japan
Blood 108:1381-7. 2006..Thus, SELDI-TOF MS would be a clinically useful tool to detect and semiquantify bioactive hepcidin in serum... - [Thrombosis of the abdominal aorta in a patient with nephrotic syndrome]H Imamura
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Ishikawa, Japan
Nippon Jinzo Gakkai Shi 43:608-12. 2001..Thrombotic complications are sometimes serious in the nephrotic patient. Assessment for the risk factors is required to warrant prophylactic anticoagulation... - [Acquired renal cystic disease and renal cell carcinoma in dialysis patients]Isao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University
Nippon Rinsho 62:366-9. 2004 - [Autosomal dominant polycystic kidney]Isao Ishikawa
Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University
Nippon Rinsho 60:541-52. 2002 - Acute renal failure with severe loin pain and patchy renal ischaemia after anaerobic exercise (ALPE) (exercise-induced acute renal failure) in a father and child with URAT1 mutations beyond the W258X mutationIsao Ishikawa
Nephrol Dial Transplant 20:1015. 2005 - Identification of genes preferentially expressed in periodontal ligament: specific expression of a novel secreted protein, FDC-SPSayaka Nakamura
Tissue Regeneration, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
Biochem Biophys Res Commun 338:1197-203. 2005..Since only normal tissue was examined, these findings suggest that FDC-SP plays an important but previously unsuspected role within oral connective tissue... - [Recent statistics of renal transplantation: treatment of end stage renal disease--comparison between the western world and Japan]Isao Ishikawa
Nippon Jinzo Gakkai Shi 46:12-9. 2004 - Somatic von Hippel-Lindau disease gene mutation in clear-cell renal carcinomas associated with end-stage renal disease/acquired cystic disease of the kidneyMinoru Yoshida
Department of Urology, Yokohama City University School of Medicine, Yokohama, Japan
Genes Chromosomes Cancer 35:359-64. 2002..However, mutations of the MET oncogene could not be found in the seven ESRD/ACDK-associated papillary RCCs examined... - Elevated IgG titers to periodontal pathogens related to Buerger diseaseYi-Wen Chen
Int J Cardiol 122:79-81. 2007..denticola, P. gingivalis and A. actinomycetemcomitans (P=0.002, P=0.039, and P=0.011, respectively). CONCLUSIONS: This study provides evidence for possible implications of periodontitis in Buerger disease... - Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger diseaseZhiyong Chen
Department of Vascular and Applied Surgery, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
Hum Genet 122:367-72. 2007..Odds ratios ranged from 4.72 to 12.57 in individuals carrying any two of these three markers. These findings suggested that the susceptibility to BD was in part controlled by genes involved in the innate and adaptive immunity... - Periodontal tissue healing following flap surgery using an Er:YAG laser in dogsKoji Mizutani
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Lasers Surg Med 38:314-24. 2006..The purpose of this study was to compare periodontal tissue healing following flap surgery using an Er:YAG laser with that of conventional surgery... - Effect of Er:YAG laser combined with rhPDGF-BB on attachment of cultured fibroblasts to periodontally involved root surfacesMahmoud Helmy Belal
Department of Oral Medicine and Periodontology, Faculty of Dentistry, El Minya University, El Minya, Egypt
J Periodontol 78:1329-41. 2007..The present study tested the direct effects of Er:YAG laser irradiation, alone or with rhPDGF-BB application, on the biocompatibility of periodontally diseased roots through fibroblast attachment and proliferation... - Cnot7-null mice exhibit high bone mass phenotype and modulation of BMP actionsKaoru Washio-Oikawa
Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
J Bone Miner Res 22:1217-23. 2007..Direct BMP2 injection induced larger bone mass in Cnot7-/- calvaria than control in vivo. These observations revealed that Cnot7 is an endogenous suppressor of bone mass and inhibits BMP actions in osteoblasts... - Rapid detection of R90H mutations in the human urate transporter 1 geneTetsuya Inazu
Department of Clinical Research, Saigata National Hospital, Joetsu, Niigata 949 3193, Japan
Ann Clin Biochem 44:189-91. 2007..A rapid method for detecting such a mutation(s) for diagnostic aid is described herein... - High incidence of actinobacillus actinomycetemcomitans infection in acute coronary syndromeKaoru Sakurai
Department of Cardiovascular Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Int Heart J 48:663-75. 2007..Periodontal pathogens, particularly A. actinomycetemcomitans, may play a role in the development of ACS... - [Recent advances in nephrology: renal transplantation]Isao Ishikawa
Nippon Jinzo Gakkai Shi 49:36-40. 2007 - Rituximab therapy for Epstein-Barr virus-related chronic hepatitis following living donor kidney transplantationKazuhide Ohta
Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Ishikawa 920 8641, Japan
Am J Kidney Dis 48:986-9. 2006..The present case illustrates the significance of early diagnosis, monitoring of viral load, and vigorous management of EBV-related disorders associated with organ transplantation... - Expression analysis of LacZ gene placed in the locus of Cnot7 exhibits its activity in osteoblasts in vivo and in mineralized nodules in vitroKaoru Washio-Oikawa
Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 101 0062, Japan
J Cell Biochem 99:538-44. 2006..Cnot7 expression was enhanced by the treatment with BMP. These data suggest that Cnot7 is expressed in osteoblasts and is associated with mineralization... - Functional polymorphisms of the FPR1 gene and aggressive periodontitis in JapaneseTomohiko Gunji
Periodontology, Department of Hard Tissue Engineering, Tokyo Medical and Dental University Graduate School, 1 5 45, Yushima, Bunkyo ku, Tokyo, 113 8549, Japan
Biochem Biophys Res Commun 364:7-13. 2007..000020). Thus, altered FPR1 function might confer increased risk to AgP... - Treatment of human class II furcation defects using connective tissue grafts, bioabsorbable membrane, and resorbable hydroxylapatite: a comparative studyMahmoud Helmy Belal
Department of Oral Medicine and Periodontology, Faculty of Dentistry, El Minya University, El Minya, Egypt
J Int Acad Periodontol 7:114-28. 2005.... - [Post-exercise acute kidney failure]Isao Ishikawa
Nippon Naika Gakkai Zasshi 94:1949-55. 2005 - [History of nephrology in the past 100 years: Kidney transplantation]Isao Ishikawa
Nippon Naika Gakkai Zasshi 91:1409-12. 2002 - Simple and rapid detection of serum antibody to periodontopathic bacteria by dot blottingYoko Kawashima
Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Japan
J Periodontal Res 37:223-9. 2002..gingivalis fimbriae were used as antigen. These results suggest that this dot blot method is a simple and rapid means of detection of serum antibodies, and that it shows promise as a chair-side assay method... - Ultrastructural analysis of bone tissue irradiated by Er:YAG LaserKatia M Sasaki
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Bunkyo ku, Tokyo 113 8549, Japan
Lasers Surg Med 31:322-32. 2002..This study was aimed to analyze the ultrastructure of bone tissue treated with Er:YAG laser, as compared to those treated with CO(2) laser and bur drilling... - High prevalence of Helicobacter pylori detected by PCR in the oral cavities of periodontitis patientsMakoto Umeda
Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
J Periodontol 74:129-34. 2003..The purpose of this study was to use nested polymerase chain reaction (PCR) to clarify whether the oral cavity acts as a reservoir for H. pylori... - S100A4: a novel negative regulator of mineralization and osteoblast differentiationWagner R Duarte
Dental Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 745, USA
J Bone Miner Res 18:493-501. 2003..These findings indicate that S100A4 is a novel negative regulator of matrix mineralization likely by modulating the process of osteoblast differentiation... - Mechanical stress induces production of angiogenic regulators in cultured human gingival and periodontal ligament fibroblastsHiroyuki Yoshino
Section of Cellular Physiological Chemistry and Section of Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Bunkyo ku, Tokyo, Japan
J Periodontal Res 38:405-10. 2003..As periodontal tissues are constantly exposed to mechanical stress during mastication, the relationship between mechanical stimulation and biochemical phenomena has been extensively investigated... - Novel isolation of alkaline phosphatase-positive subpopulation from periodontal ligament fibroblastsYuya Murakami
Section of Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
J Periodontol 74:780-6. 2003..The aim of the present study was to isolate the osteogenic population of PDLFs according to their expression of ALP... - Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Japanese populationYasuo Takeuchi
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
J Periodontol 74:1460-9. 2003..Although A. actinomycetem- comitans was also detected in AgP patients, the prevalence of this bacterium was much lower than that of P. gingivalis... - Effect of low dose Actinobacillus actinomycetemcomitans lipopolysaccharide pretreatment on cytokine production by human whole bloodTsutomu Nakamura
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
J Periodontal Res 39:129-35. 2004..CONCLUSION: A low dose of bloodstream LPS found in periodontitis patients appears to be sufficient to prime monocytes, and may be capable of affecting the systemic responses of immune and inflammatory cells... - Expression of membrane-bound and soluble receptor activator of NF-kappaB ligand (RANKL) in human T cellsFumiko Kanamaru
Department of Molecular Immunology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan
Immunol Lett 94:239-46. 2004..The mAbs that were derived in this study may be useful for investigating the regulation and function of RANKL in immune responses and bone remodeling... - Histological and TEM examination of early stages of bone healing after Er:YAG laser irradiationAmir Pourzarandian
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
Photomed Laser Surg 22:342-50. 2004..The aim of this study was to analyze the early healing process of bone tissue irradiated by Er:YAG laser and compare it with that treated by mechanical drilling and CO(2) laser... - The distribution of periodontopathic bacteria among Japanese children and their parentsMakoto Umeda
Section of Periodontology, Department of Hard Tissue Engineering, Tokyo Medical and Dental University, Japan
J Periodontal Res 39:398-404. 2004..The purpose of this study was to investigate the distribution of periodontopathic bacteria in oral cavities of children and their parents and the relationship between the bacterial findings and clinical parameters... - S100A4 inhibition by RNAi up-regulates osteoblast related genes in periodontal ligament cellsChiyu Kato
Periodontology, Department of Hard Tissue Engineering, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
Biochem Biophys Res Commun 326:147-53. 2005..These results indicate that S100A4 suppresses the expression of osteoblastic genes in PDL cells and may thus inhibit mineralization in the PDL... - Effects of single-visit full-mouth ultrasonic debridement versus quadrant-wise ultrasonic debridementGeena Koshy
Periodontology, Department of Hard Tissue Engineering, Tokyo Medical and Dental University, Tokyo 113 8549, Japan
J Clin Periodontol 32:734-43. 2005..The aim of this randomized controlled clinical trial was to determine the effects of single-visit full-mouth ultrasonic debridement versus quadrant-wise therapy... - Intraductal papillary mucinous tumor of the pancreas associated with autosomal dominant polycystic kidney diseaseHiroshi Naitoh
Gastroenterology and Proctology Center, Social Insurance Gumma Chuo General Hospital, Maebashi, Japan
J Gastrointest Surg 9:843-5. 2005..Therefore, we suggest that some genetic interactions may exist between ADPKD and pancreatic carcinogenesis... - Binary regulation of interleukin (IL)-6 production by EP1 and EP2/EP4 subtypes of PGE2 receptors in IL-1beta-stimulated human gingival fibroblastsKazuyuki Noguchi
Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Japan
J Periodontal Res 37:29-36. 2002..Expression and function of EP1, EP2 and EP4 receptors in HGF may play critical roles in controlling inflammatory periodontal conditions...