F Umehara

Summary

Affiliation: Kagoshima University
Country: Japan

Publications

  1. ncbi Axonal damage revealed by accumulation of beta-amyloid precursor protein in HTLV-I-associated myelopathy
    F Umehara
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, Sakuragaoka 8 35 1, Kagoshima, Japan
    J Neurol Sci 176:95-101. 2000
  2. ncbi A novel mutation of desert hedgehog in a patient with 46,XY partial gonadal dysgenesis accompanied by minifascicular neuropathy
    F Umehara
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, Kagoshima, Japan
    Am J Hum Genet 67:1302-5. 2000
  3. ncbi Clinical phenotype in X-linked Charcot-Marie-Tooth disease with an entire deletion of the connexin 32 coding sequence
    M Nakagawa
    Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima, Kagoshima 890 8520, Japan
    J Neurol Sci 185:31-7. 2001
  4. ncbi Expression of vascular endothelial growth factor in tuberculous meningitis
    W Matsuyama
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Sakuragaoka 8 35 1, Kagoshima 890 8520, Japan
    J Neurol Sci 186:75-9. 2001
  5. ncbi Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis
    E Matsuura
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, 8 35 1, Sakuragaoka, Kagoshima City, Kagoshima, Japan
    J Neurol Sci 173:45-52. 2000
  6. ncbi Chronic progressive cervical myelopathy with HTLV-I infection: Variant form of HAM/TSP?
    F Umehara
    Department of Neurology, Graduate School of Kagoshima University, Sakuragaoka 8 35 1, Kagoshima 8900075, Japan
    Neurology 63:1276-80. 2004
  7. ncbi Early clinical signs and imaging findings in Gerstmann-Sträussler-Scheinker syndrome (Pro102Leu)
    H Arata
    Department of Neurology and Geriatrics, Kagoshima University School of Medicine, Kagoshima City, Japan
    Neurology 66:1672-8. 2006
  8. ncbi Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy
    F Umehara
    Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan
    Neurology 66:289. 2006
  9. ncbi Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome
    K Michizono
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Japan
    Neurology 56:807-10. 2001
  10. ncbi SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma
    R Hirano
    Department of Neurology and Geriatrics, Kagoshima University School of Medicine, Kagoshima City, Kagoshima, Japan
    Neurology 63:577-80. 2004

Collaborators

Detail Information

Publications17

  1. ncbi Axonal damage revealed by accumulation of beta-amyloid precursor protein in HTLV-I-associated myelopathy
    F Umehara
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, Sakuragaoka 8 35 1, Kagoshima, Japan
    J Neurol Sci 176:95-101. 2000
    ..Impairment of fast axonal transport may contribute to the development of disability in patients with HAM/TSP...
  2. ncbi A novel mutation of desert hedgehog in a patient with 46,XY partial gonadal dysgenesis accompanied by minifascicular neuropathy
    F Umehara
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, Kagoshima, Japan
    Am J Hum Genet 67:1302-5. 2000
    ..This is the first report of a human DHH gene mutation, and the findings demonstrate that mutation of the DHH gene may cause 46, XY PGD associated with minifascicular neuropathy...
  3. ncbi Clinical phenotype in X-linked Charcot-Marie-Tooth disease with an entire deletion of the connexin 32 coding sequence
    M Nakagawa
    Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima, Kagoshima 890 8520, Japan
    J Neurol Sci 185:31-7. 2001
    ....
  4. ncbi Expression of vascular endothelial growth factor in tuberculous meningitis
    W Matsuyama
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Sakuragaoka 8 35 1, Kagoshima 890 8520, Japan
    J Neurol Sci 186:75-9. 2001
    ..We found the expression of VEGF in tuberculous meningitis and think that VEGF reflects its activity...
  5. ncbi Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis
    E Matsuura
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, 8 35 1, Sakuragaoka, Kagoshima City, Kagoshima, Japan
    J Neurol Sci 173:45-52. 2000
    ..Taken together, those data suggest that MMP-9 in CSF may be a useful marker of encephalitogenecity during the course of subacute meningitis...
  6. ncbi Chronic progressive cervical myelopathy with HTLV-I infection: Variant form of HAM/TSP?
    F Umehara
    Department of Neurology, Graduate School of Kagoshima University, Sakuragaoka 8 35 1, Kagoshima 8900075, Japan
    Neurology 63:1276-80. 2004
    ..To investigate the role of human T-lymphotrophic virus type I (HTLV-I) infection in four patients who developed slowly progressive myelopathy with abnormal MRI lesions in the cervical cord levels...
  7. ncbi Early clinical signs and imaging findings in Gerstmann-Sträussler-Scheinker syndrome (Pro102Leu)
    H Arata
    Department of Neurology and Geriatrics, Kagoshima University School of Medicine, Kagoshima City, Japan
    Neurology 66:1672-8. 2006
    ..Normal cerebellar MRI and abnormal cerebral SPECT findings are characters of early GSS102...
  8. ncbi Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy
    F Umehara
    Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan
    Neurology 66:289. 2006
  9. ncbi Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome
    K Michizono
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Japan
    Neurology 56:807-10. 2001
    ..Serum levels of VEGF and TIMP-1 were strongly correlated with each other. Increased circulating levels of MMP-1, -2, -3, -9, and TIMP-1 may lead to a better understanding the pathogenesis of POEMS syndrome...
  10. ncbi SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma
    R Hirano
    Department of Neurology and Geriatrics, Kagoshima University School of Medicine, Kagoshima City, Kagoshima, Japan
    Neurology 63:577-80. 2004
    ..The consistent phenotypic features associated with SBF2 mutations are early-onset demyelinating neuropathy, myelin folding, and markedly decreased motor nerve conduction velocities; glaucoma associates with SBF2 nonsense mutations...
  11. ncbi The clinical and pathological features of peripheral neuropathy accompanied with HTLV-I associated myelopathy
    T Kiwaki
    The Third Department of Internal Medicine, Kagoshima University School of Medicine, Sakuragaoka 8-35-1, Kagoshima, Japan
    J Neurol Sci 206:17-21. 2003
    ..The pathologic changes were correlated with neither the duration of disease nor human T lymphotropic virus type I (HTLV-I) proviral load. This study suggests that peripheral nerves could be involved in HAM/TSP...
  12. ncbi Neurologic manifestations of Kanzaki disease
    F Umehara
    Department of Neurology and Geriatrics, Graduate School of Medicine and Dental Sciences, Kagoshima University, Japan
    Neurology 62:1604-6. 2004
    ..These findings suggest that Kanzaki disease may develop neurologic complications in the CNS and peripheral nervous system...
  13. ncbi Gap junction protein beta 1 (GJB1) mutations and central nervous system symptoms in X-linked Charcot-Marie-Tooth disease
    H Takashima
    Third Department of Internal Medicine, Kagoshima University Faculty of Medicine, Kagoshima 890 8520, Japan
    Acta Neurol Scand 107:31-7. 2003
    ..To clarify the clinical variability, including central nervous system (CNS) involvement, in X-linked Charcot-Marie-Tooth disease (CMTX) patients...
  14. ncbi Age associated axonal features in HNPP with 17p11.2 deletion in Japan
    H Koike
    Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan
    J Neurol Neurosurg Psychiatry 76:1109-14. 2005
    ..Unlike Charcot-Marie-Tooth disease type 1A, age associated axonal damage may not occur unless the nerves are subjected to compression...
  15. ncbi Motor-sensory neuropathy with minifascicle formation in a woman with normal karyotype
    A Malandrini
    Department of Neurological and Behavioural Sciences, University of Siena, 53100 Siena, Italy
    Neurology 65:776. 2005
  16. ncbi Phenotypes of X-linked Charcot-Marie-Tooth disease and altered trafficking of mutant connexin 32 (GJB1)
    W Matsuyama
    Third Department of Internal Medicine, Kagoshima University, Faculty of Medicine, Sakuragaoka, Japan
    J Hum Genet 46:307-13. 2001
    ..These altered expressions indicated loss of active gap junction formation with different expression abnormalities in these CMTX patients...
  17. ncbi A novel MPZ gene mutation in dominantly inherited neuropathy with focally folded myelin sheaths
    M Nakagawa
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Kagoshima City, Japan
    Neurology 52:1271-5. 1999
    ..Our study suggests that the characteristic pathologic findings of the sural nerve in these patients are closely related to the site and nature of amino acid substitutions of the MPZ gene...