Katsuaki Sato

Summary

Affiliation: Kagoshima University
Country: Japan

Publications

  1. ncbi request reprint Human peripheral blood monocyte-derived interleukin-10-induced semi-mature dendritic cells induce anergic CD4(+) and CD8(+) T cells via presentation of the internalized soluble antigen and cross-presentation of the phagocytosed necrotic cellular fragments
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, Kagoshima City, Japan
    Cell Immunol 215:186-94. 2002
  2. ncbi request reprint Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    Katsuaki Sato
    Department of Immunology and Medical Zoology, Division of Human Retroviruses, Center for Chronic Viral Diseases, School of Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan
    Blood 101:3581-9. 2003
  3. ncbi request reprint Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima City, 890 8520, Kagoshima, Japan
    Immunity 18:367-79. 2003
  4. ncbi request reprint Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity
    Tomofumi Uto
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima, Japan
    J Immunol 178:2979-86. 2007
  5. ncbi request reprint Potent activation of antigen-specific T cells by antigen-loaded nanospheres
    Xin Wang
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8544, Japan
    Immunol Lett 98:123-30. 2005
  6. ncbi request reprint Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice
    Masaki Kawamura
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
    J Med Virol 76:7-15. 2005
  7. ncbi request reprint An abortive ligand-induced activation of CCR1-mediated downstream signaling event and a deficiency of CCR5 expression are associated with the hyporesponsiveness of human naive CD4+ T cells to CCL3 and CCL5
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan
    J Immunol 168:6263-72. 2002
  8. doi request reprint Relationship of aquaporin 1, 3, and 5 expression in lung cancer cells to cellular differentiation, invasive growth, and metastasis potential
    Yuichiro Machida
    Department of Pathophysiological and Experimental Pathology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa 920 0293, Japan
    Hum Pathol 42:669-78. 2011
  9. ncbi request reprint Effectiveness of anti-folate receptor beta antibody conjugated with truncated Pseudomonas exotoxin in the targeting of rheumatoid arthritis synovial macrophages
    Ryusaku Nagayoshi
    Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
    Arthritis Rheum 52:2666-75. 2005
  10. ncbi request reprint TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse
    Katsuaki Sato
    Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa, Japan
    J Immunol 174:4025-33. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Human peripheral blood monocyte-derived interleukin-10-induced semi-mature dendritic cells induce anergic CD4(+) and CD8(+) T cells via presentation of the internalized soluble antigen and cross-presentation of the phagocytosed necrotic cellular fragments
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, Kagoshima City, Japan
    Cell Immunol 215:186-94. 2002
    ..Thus, our results suggest that IL-10-induced semi-mDCs induce an Ag-specific anergy in CD4(+) and CD8(+) T cells via presentation of the internalized protein and cross-presentation of the phagocytosed cellular fragments...
  2. ncbi request reprint Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    Katsuaki Sato
    Department of Immunology and Medical Zoology, Division of Human Retroviruses, Center for Chronic Viral Diseases, School of Medicine, Kagoshima University, Kagoshima City, Kagoshima, Japan
    Blood 101:3581-9. 2003
    ..Thus, the modulation of T cell-mediated immunity by regulatory DCs provides a novel therapeutic approach for immunopathogenic diseases...
  3. ncbi request reprint Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima City, 890 8520, Kagoshima, Japan
    Immunity 18:367-79. 2003
    ..Thus, the use of rDCs may be therapeutically useful for the treatment of acute GVHD and leukemia relapse in allogeneic BMT...
  4. ncbi request reprint Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity
    Tomofumi Uto
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima, Japan
    J Immunol 178:2979-86. 2007
    ..These results suggest that Ag-carrying gamma-PGA NPs are capable of inducing strong cellular and humoral immune responses and might be potentially useful as effective vaccine adjuvants for the therapy of infectious diseases...
  5. ncbi request reprint Potent activation of antigen-specific T cells by antigen-loaded nanospheres
    Xin Wang
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8544, Japan
    Immunol Lett 98:123-30. 2005
    ..These results suggest that NS can be used as an efficient antigen delivery system to DC for a variety of vaccines, such as an anti-human immunodeficiency virus type 1 vaccine...
  6. ncbi request reprint Induction of dendritic cell-mediated immune responses against HIV-1 by antigen-capturing nanospheres in mice
    Masaki Kawamura
    Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
    J Med Virol 76:7-15. 2005
    ..These results suggest that the use of HIV-1-NS may provide a novel and promising approach for the induction of humoral and cellular immune responses to HIV-1...
  7. ncbi request reprint An abortive ligand-induced activation of CCR1-mediated downstream signaling event and a deficiency of CCR5 expression are associated with the hyporesponsiveness of human naive CD4+ T cells to CCL3 and CCL5
    Katsuaki Sato
    Department of Immunology and Medical Zoology, School of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan
    J Immunol 168:6263-72. 2002
    ..Thus, a failure of the ligand-induced activation of CCR1-mediated downstream signaling event as well as a deficiency of CCR5 expression may be involved in the hyporesponsiveness of naive CD4(+) T cells to CCL3 and CCL5...
  8. doi request reprint Relationship of aquaporin 1, 3, and 5 expression in lung cancer cells to cellular differentiation, invasive growth, and metastasis potential
    Yuichiro Machida
    Department of Pathophysiological and Experimental Pathology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa 920 0293, Japan
    Hum Pathol 42:669-78. 2011
    ....
  9. ncbi request reprint Effectiveness of anti-folate receptor beta antibody conjugated with truncated Pseudomonas exotoxin in the targeting of rheumatoid arthritis synovial macrophages
    Ryusaku Nagayoshi
    Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
    Arthritis Rheum 52:2666-75. 2005
    ....
  10. ncbi request reprint TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse
    Katsuaki Sato
    Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa, Japan
    J Immunol 174:4025-33. 2005
    ..Thus, gene transfer of TRAIL to DCs is a novel modality for the treatment of acute GVHD and leukemia relapse by selective targeting of pathogenic T cells and leukemic cells...
  11. ncbi request reprint Regulatory dendritic cells protect against allergic airway inflammation in a murine asthmatic model
    Shigeharu Fujita
    Laboratory for Dendritic Cell Immunobiology, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan
    J Allergy Clin Immunol 121:95-104.e7. 2008
    ..Dendritic cells (DCs) are crucial for the induction of immunity and tolerance. Despite an improved understanding of the DC-mediated control of T(H)1-biased immunity, little is known about how DCs regulate T(H)2-mediated immunity...
  12. ncbi request reprint Regulatory dendritic cells protect against cutaneous chronic graft-versus-host disease mediated through CD4+CD25+Foxp3+ regulatory T cells
    Shigeharu Fujita
    Laboratory for Dendritic Cell Immunobiology, Rikagaku Kenkyusho RIKEN Research Center for Allergy and Immunology, Yokohama, Japan
    Blood 110:3793-803. 2007
    ..Thus, immunotherapy with DC(regs) is a promising strategy for the treatment of cGVHD in alloBMT mediated through the induction of a dominant tolerance involving CD4(+)CD25(+)Foxp3(+) T(R) cells...
  13. ncbi request reprint Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells
    Yumiko Matsumura
    Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    J Immunol 179:2170-9. 2007
    ..These results indicate an important role of SOCS3 in determining on immunity or tolerance by DCs...
  14. ncbi request reprint Results of a phase I clinical study using autologous tumour lysate-pulsed monocyte-derived mature dendritic cell vaccinations for stage IV malignant melanoma patients combined with low dose interleukin-2
    Hitomi Nagayama
    Division of Cell Processing, Department of Advanced Medical Science, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Melanoma Res 13:521-30. 2003
    ....
  15. ncbi request reprint Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response
    Shigeharu Fujita
    Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa 230 0045 Japan
    Blood 107:3656-64. 2006
    ..Thus, a subset of tolerogenic DCs act as potential regulators of the host inflammatory response, and they might have preventive and therapeutic potential for the treatment of systemic as well as local inflammatory diseases...
  16. ncbi request reprint Thyroglobulin-pulsed human monocyte-derived dendritic cells induce CD4+ T cell activation
    Mariko Morishita
    Department of Advanced Medical Science, The University of Tokyo, 4 6 1 Shirokanedai, Tokyo 108 8639, Japan
    Int J Mol Med 13:33-9. 2004
    ....
  17. ncbi request reprint Extrauterine endometrial stromal sarcoma with JAZF1/JJAZ1 fusion confirmed by RT-PCR and interphase FISH presenting as an inguinal tumor
    Katsuaki Sato
    Department of Pathophysiological and Experimental Pathology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa, 920 0293, Japan
    Virchows Arch 450:349-53. 2007
    ....
  18. ncbi request reprint Dendritic cells: nature and classification
    Katsuaki Sato
    Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa, Japan
    Allergol Int 56:183-91. 2007
    ..The diverse functions of DCs in immune regulation depend on the heterogeneity of DC subsets and their functional plasticity. Here we review recent progress in our understanding of the nature and classification of DCs...
  19. ncbi request reprint Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model
    Naomi Yamashita
    Department of Pharmacology, Research Institute of Pharmaceutical Sciences, Musashino University, Shinmachi Nishitokyo shi, Tokyo
    J Allergy Clin Immunol 117:1040-6. 2006
    ....
  20. ncbi request reprint Carbonic anhydrase II is a tumor vessel endothelium-associated antigen targeted by dendritic cell therapy
    Kenta Yoshiura
    Department of Advanced Medical Science, University of Tokyo, Japan
    Clin Cancer Res 11:8201-7. 2005
    ....