Takuro Kanekura

Summary

Affiliation: Kagoshima University
Country: Japan

Publications

  1. ncbi request reprint Treatment of pyoderma gangrenosum with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Ther Apher Dial 9:292-6. 2005
  2. ncbi request reprint Ultrastructural localization of basigin in normal human epidermis
    X Chen
    Department of Dermatology, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima, 890 8520, Japan
    Histochem Cell Biol 115:465-70. 2001
  3. ncbi request reprint Improvement of adult Still's disease with granulocyte and monocyte adsorption apheresis
    T Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    Clin Exp Dermatol 29:410-2. 2004
  4. ncbi request reprint Treatment of Behçet's disease with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    J Am Acad Dermatol 51:S83-7. 2004
  5. ncbi request reprint Three dimensional structural studies of alpha-N-acetylgalactosaminidase (alpha-NAGA) in alpha-NAGA deficiency (Kanzaki disease): different gene mutations cause peculiar structural changes in alpha-NAGAs resulting in different substrate specificities and c
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol Sci 37:15-20. 2005
  6. ncbi request reprint Selenium deficiency: report of a case
    T Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    Clin Exp Dermatol 30:346-8. 2005
  7. doi request reprint CD147/basigin promotes progression of malignant melanoma and other cancers
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol Sci 57:149-54. 2010
  8. ncbi request reprint Immunoelectron-microscopic detection of globotriaosylceramide accumulated in the skin of patients with Fabry disease
    T Kanekura
    Anatomy, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Br J Dermatol 153:544-8. 2005
  9. ncbi request reprint Eruptive pruritic papular porokeratosis: a pruritic variant of porokeratosis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 33:813-6. 2006
  10. ncbi request reprint Granulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Ther Apher Dial 10:287-90. 2006

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Treatment of pyoderma gangrenosum with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Ther Apher Dial 9:292-6. 2005
    ..The turgid skin lesions containing pustules and ulcers of the other patient showed amelioration and a marked decrease in the volume of exudate. Our results suggest that GCAP is a useful treatment modality for pyoderma gangrenosum...
  2. ncbi request reprint Ultrastructural localization of basigin in normal human epidermis
    X Chen
    Department of Dermatology, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima, 890 8520, Japan
    Histochem Cell Biol 115:465-70. 2001
    ..Microvilli on basal and suprabasal keratinocytes might play roles in the differentiation of keratinocytes through basigin on the tips of microvilli...
  3. ncbi request reprint Improvement of adult Still's disease with granulocyte and monocyte adsorption apheresis
    T Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    Clin Exp Dermatol 29:410-2. 2004
    ..Her joint pain responded dramatically to the GCAP therapy, suggesting that GCAP may be useful for treating adult Still's disease. We present a detailed description of the patient and this novel therapy...
  4. ncbi request reprint Treatment of Behçet's disease with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    J Am Acad Dermatol 51:S83-7. 2004
    ..Our results demonstrate that granulocyte and monocyte adsorption apheresis may be useful for treating orogenital ulcerations of Behçet's disease...
  5. ncbi request reprint Three dimensional structural studies of alpha-N-acetylgalactosaminidase (alpha-NAGA) in alpha-NAGA deficiency (Kanzaki disease): different gene mutations cause peculiar structural changes in alpha-NAGAs resulting in different substrate specificities and c
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol Sci 37:15-20. 2005
    ..Although they are on the same codon, the clinical manifestation was more severe in R329W because an amino acid substitution led to protein instability resulting in structural change, which is greater in R329W than in R329Q...
  6. ncbi request reprint Selenium deficiency: report of a case
    T Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    Clin Exp Dermatol 30:346-8. 2005
    ..The clinical similarity to zinc deficiency and the literature yielded important clues for a diagnosis of selenium deficiency in this patient...
  7. doi request reprint CD147/basigin promotes progression of malignant melanoma and other cancers
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol Sci 57:149-54. 2010
    ..These findings strongly suggest CD147 as a possible therapeutic target for overcoming metastasis and MDR, major obstacles to the effective treatment of malignant cancers...
  8. ncbi request reprint Immunoelectron-microscopic detection of globotriaosylceramide accumulated in the skin of patients with Fabry disease
    T Kanekura
    Anatomy, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Br J Dermatol 153:544-8. 2005
    ..The major glycolipid accumulated in tissue is globotriaosylceramide (GL-3). To date, no direct detection of GL-3 by immunoelectron microscopy has been reported...
  9. ncbi request reprint Eruptive pruritic papular porokeratosis: a pruritic variant of porokeratosis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 33:813-6. 2006
    ..Histopathological examination revealed the characteristic cornoid lamellae. We describe this case in detail and provide a review of the published work...
  10. ncbi request reprint Granulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Ther Apher Dial 10:287-90. 2006
    ..9 MFI (mean fluorescence intensity) to 27.0 MFI (normal controls: 10.5 +/- 1.2 MFI) by GCAP, respectively. These results suggest that GCAP is useful for skin disorders with leucocytoclastic vasculitis...
  11. ncbi request reprint Skin disorders with prominent eosinophilic infiltration treated successfully with nicotine. Report of two cases
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Dermatology 208:153-7. 2004
    ..Nicotine was effective in the treatment of skin disorders attributable to neutrophils such as pyoderma gangrenosum and orogenital ulcerations due to Behçet's disease...
  12. ncbi request reprint Treatment of psoriatic arthritis with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, University Faculty of Medicine, Kogoshima, Japan
    J Am Acad Dermatol 50:242-6. 2004
    ..Treatment with GCAP resulted in remarkable clearing of joint pain, suggesting that GCAP is valuable for treating arthritis as well as skin disorders. We present a detailed description of these patients and this novel therapy...
  13. ncbi request reprint Granulocyte and monocyte adsorption apheresis (GCAP) for refractory skin diseases caused by activated neutrophils and psoriatic arthritis: evidence that GCAP removes Mac-1-expressing neutrophils
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Ther Apher Dial 10:247-56. 2006
    ..GCAP was useful for treating neutrophilic dermatoses and PsA. GCAP adsorbs Mac-1-expressing neutrophils to the CA beads by the binding of complement component (iC3b) on CA beads and CD11b expressed on activated neutrophils...
  14. ncbi request reprint Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima 890 8530, Japan
    Int J Cancer 99:520-8. 2002
    ..Basigin is highly expressed in melanoma cells and may play an important role in their invasiveness and metastasis by stimulating surrounding fibroblasts to express MMPs...
  15. ncbi request reprint Beneficial effects of synthetic phospholipid polymer, poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate), on stratum corneum function
    T Kanekura
    Department of Dermatology, Kagoshima University Faculty of Medicine, Japan
    Clin Exp Dermatol 27:230-4. 2002
    ..Our results indicate that this substance may be useful clinically in the treatment of dry skin...
  16. ncbi request reprint Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus
    T Kanekura
    Department of Dermatology, Kagoshima University Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Br J Dermatol 148:353-6. 2003
    ..Although the study is preliminary, the results demonstrate that topical tacrolimus may be useful for treating the malar rash of SLE...
  17. ncbi request reprint The involvement of NF-kappaB in the constitutive overexpression of cyclooxygenase-2 in cyclooxygenase-1 null cells
    Takuro Kanekura
    Department of Dermatology, Kagoshima University Faculty of Medicine, Japan
    Biochim Biophys Acta 1542:14-22. 2002
    ....
  18. ncbi request reprint Treatment of pustular psoriasis with granulocyte and monocyte adsorption apheresis
    Takuro Kanekura
    Department of Dermatology, Kagoshima University, Japan
    J Am Acad Dermatol 49:329-32. 2003
    ..We present detailed descriptions of these patients and this novel therapy...
  19. doi request reprint p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells
    Shigeto Matsushita
    Department of Dermatology, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol Sci 68:19-24. 2012
    ..The p53R2 gene product increases the deoxynucleotide triphosphate pool in the nucleus; this facilitates DNA repair and synthesis...
  20. doi request reprint CD147-targeting siRNA inhibits cell-matrix adhesion of human malignant melanoma cells by phosphorylating focal adhesion kinase
    Rie Nishibaba
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 39:63-7. 2012
    ..Our results suggest that CD147/basigin regulates the adhesion of MM cells to extracellular matrices and of integrin β1 signaling via the phosphorylation of FAK...
  21. doi request reprint Metastatic cutaneous squamous cell carcinoma treated successfully with surgery, radiotherapy and S-1/cisplatin chemotherapy
    Shigeto Matsushita
    Department of Dermatology, Field of Sensory Organology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 37:666-70. 2010
    ..The chemotherapeutic agent S-1/cisplatin was selected based on results of the histoculture drug response assay. The patient responded dramatically to this multidisciplinary treatment and complete remission was achieved...
  22. doi request reprint ER signaling is activated to protect human HaCaT keratinocytes from ER stress induced by environmental doses of UVB
    Kentaro Mera
    Department of Dermatology, Field of Sensory Organology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Biochem Biophys Res Commun 397:350-4. 2010
    ..This is the first report to show ER signaling in UVB-irradiated keratinocytes...
  23. doi request reprint Indication for random skin biopsy for the diagnosis of intravascular large B cell lymphoma
    Yuko Higashi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Dermatology 224:46-50. 2012
    ..The use of random skin biopsy (RSB) to diagnose intravascular large B cell lymphoma (IVLBCL) has increased...
  24. ncbi request reprint Negative feedback regulation of phosphatidylinositol 3-kinase/Akt pathway by over-expressed cyclooxygenase-2 in human epidermal cancer cells
    Koichiro Takeda
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 31:516-23. 2004
    ..COX-2 inhibitor NS398 up-regulated Akt phosphorylation. These results imply that constitutively over-expressed COX-2 down-regulates the Akt phosphorylation through a negative feedback mechanism...
  25. doi request reprint Snail modulates cell metabolism in MDCK cells
    Misako Haraguchi
    Department of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8544, Japan
    Biochem Biophys Res Commun 432:618-25. 2013
    ..On the other hand, the reduced requirements for oxygen and nutrients from the surrounding environment, might confer the resistance to cell death induced by hypoxia and malnutrition...
  26. doi request reprint MK615, a Prunus mume Steb. Et Zucc ('Ume') extract, attenuates the growth of A375 melanoma cells by inhibiting the ERK1/2-Id-1 pathway
    Ko ichi Tada
    Department of Dermatology, Cardiovascular and Respiratory Disorders Advanced Therapeutics, Kagoshima University, Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Phytother Res 26:833-8. 2012
    ..Moreover, the expression of Bcl-2 was decreased by both MK615 and Id-1-specific RNAi in A375 cells. The results suggest that MK615 is a potential therapeutic agent for treating malignant melanoma...
  27. doi request reprint A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis
    Juan Su
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Cancer Lett 273:140-7. 2009
    ..These results strongly suggest that highly-expressed CD147 interacts with MCT1 and 4 to promote tumor cell glycolysis, resulting in the progression of MM...
  28. ncbi request reprint Immunohistochemical comparison of beta-catenin expression by human normal epidermis and epidermal tumors
    Keiko Fukumaru
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 34:746-53. 2007
    ....
  29. doi request reprint Proteome analysis of multidrug resistance of human oral squamous carcinoma cells using CD147 silencing
    Ye Hong Kuang
    Department of Dermatology, Xiang Ya Hospital, Central South University, Hunan, 410008, China, Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, 890 8520, Japan
    J Proteome Res 7:4784-91. 2008
    ..We document an abundance of molecules that interact with CD147 in the MDR of human oral squamous carcinoma cells. Additional studies are needed to investigate these novel target proteins of CD147...
  30. doi request reprint Retinoic acids exhibit anti-fibrotic activity through the inhibition of 5-lipoxygenase expression in scleroderma fibroblasts
    Rong Xiao
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan
    J Dermatol 38:345-53. 2011
    ....
  31. ncbi request reprint Extramammary Paget's disease/carcinoma successfully treated with a combination chemotherapy: report of two cases
    Yuji Mochitomi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan
    J Dermatol 32:632-7. 2005
    ..We describe two patients with EMPD/C whose metastatic lesions responded well to this combination of chemotherapy...
  32. doi request reprint Thrombomodulin exerts cytoprotective effect on low-dose UVB-irradiated HaCaT cells
    Masahiro Iwata
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    Biochem Biophys Res Commun 377:642-7. 2008
    ....
  33. ncbi request reprint Contact dermatitis due to orchids (Cymbidium and Oncidium)
    Masahiro Iwata
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
    J Dermatol 33:115-7. 2006
    ..A diagnosis of contact dermatitis attributable to the cultivated orchids was made...
  34. doi request reprint The 3G5 antigen is expressed in dermal mast cells but not pericytes
    Akira Gushi
    Department of Dermatology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Japan
    J Cutan Pathol 35:278-84. 2008
    ..This study was designed to determine whether the expression of the 3G5 antigen is restricted to specific stages of pericyte development, or if it is expressed in other cells rather than pericytes in capillary vessels...
  35. doi request reprint Abcb10 Role in Heme Biosynthesis In Vivo: Abcb10 Knockout in Mice Causes Anemia with Protoporphyrin IX and Iron Accumulation
    Masatatsu Yamamoto
    Department of Molecular Oncology, Graduate School Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
    Mol Cell Biol 34:1077-84. 2014
    ..These results suggest a critical role for Abcb10 in heme biosynthesis and provide new insights into the pathogenesis of erythropoietic protoporphyria and sideroblastic anemia. ..
  36. ncbi request reprint Possible role of transcriptional coactivator P/CAF and nuclear acetylation in calcium-induced keratinocyte differentiation
    Hisashi Kawabata
    Department of Dermatology and Laboratory of Molecular Medicine, Kagoshima University, Faculty of Medicine, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Biol Chem 277:8099-105. 2002
    ..Our results suggest that P/CAF HAT activity and induction of ap97 are involved in calcium-dependent keratinocyte differentiation...
  37. doi request reprint Evaluation of a newly-developed immunochromatography strip test for diagnosing dermatophytosis
    Yuko Higashi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima City Hospital, Kagoshima, Japan
    Int J Dermatol 51:406-9. 2012
    ..Traditionally, dermatophytosis, a common disease affecting millions of people world-wide, has been diagnosed by direct microscopy and fungal culture. The immunochromatography (ICG) strip test was recently developed...
  38. ncbi request reprint Beneficial effects of tissue inhibitor of metalloproteinases-2 (TIMP-2) on chronic dermatitis
    Hayao Miyoshi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 32:346-53. 2005
    ..05). Our results suggest that NC/Kuj mice with Df extract-induced chronic eczema may be a useful model for investigating chronic dermatitis, and that TIMP-2 may be a good agent for treating chronic dermatitis as well as chronic ulcers...
  39. ncbi request reprint Estrogen dermatitis: a dendritic-cell-mediated allergic condition
    Shinichi Yotsumoto
    Department of Dermatology, Kagoshima University Faculty of Medicine, Kagoshima, Japan
    Dermatology 207:265-8. 2003
    ..Most estrogen dermatitides are induced by local or systemic contact dermatitis where dendritic cells are central, and tamoxifen has a blocking effect on dendritic cells...
  40. ncbi request reprint Multicentric Castleman disease with cutaneous manifestations: report of 2 cases and comparison with systemic plasmacytosis
    Yuko Higashi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Dermatology 214:170-3. 2007
    ..PCR disclosed clonal T-cell receptor gene rearrangement in the bone marrow cells of 1 patient. We discuss the possible relationship between multicentric Castleman disease and systemic plasmacytosis as well as plasma cell proliferation...
  41. ncbi request reprint Primary squamous cell carcinoma of the frontal sinus
    Nobuyo Yoshida
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 33:855-7. 2006
    ..Herein, we present a detailed description of this patient and a review of the published work...
  42. doi request reprint Epidermodysplasia-verruciformis-like eruption associated with gamma-papillomavirus infection in a patient with adult T-cell leukemia
    Kazuhiro Kawai
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Dermatology 219:274-8. 2009
    ..This is the first documentation of an association between EV-like eruption and gamma-papillomavirus infection...
  43. doi request reprint The transcription factor Snail expressed in cutaneous squamous cell carcinoma induces epithelial-mesenchymal transition and down-regulates COX-2
    Mitsuyoshi Shimokawa
    Department of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8544, Japan
    Biochem Biophys Res Commun 430:1078-82. 2013
    ..Consistent with these observations, reporter assays revealed that COX-2 promoter activity was repressed upon Snail overexpression. Thus Snail down-regulates COX-2 in these cells...
  44. ncbi request reprint Immunohistochemical studies comparing the localization of type XV collagen in normal human skin and skin tumors with that of type IV collagen
    Tomoko Fukushige
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima, Japan
    J Dermatol 32:74-83. 2005
    ..These findings suggest that type XV collagen plays a role in the adherence of the basement membrane to surrounding connective tissue and that it may be associated with the tumorigenesis of keratinocytes and melanocytes...
  45. doi request reprint Case of adult T-cell leukemia with pulmonary involvement presenting as nodular shadows
    Kimitaka Oyama
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima, Japan
    J Dermatol 35:225-8. 2008
    ..Our review of the published work found only two previously reported cases of ATL with pulmonary involvement manifested as nodular shadows. Herein, we present details on the third case...
  46. ncbi request reprint Spontaneous regression of recurrent and metastatic Merkel cell carcinoma
    Hidemichi Kubo
    Department of Dermatology, Field of Sensory Organology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 34:773-7. 2007
    ..Although she received no treatment due to her poor condition, the recurrent metastatic lesion regressed spontaneously within 2 months...
  47. ncbi request reprint Granulomas induced by subcutaneous injection of leuprorelin acetate
    Ryoko Sakamoto
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 33:43-5. 2006
    ..A biopsy of the nodules disclosed epithelioid granulomatous inflammation and resulted in a diagnosis of drug-induced granulomatous reaction to leuprorelin acetate...
  48. doi request reprint Role for E-cadherin as an inhibitory receptor on epidermal gammadelta T cells
    Youhei Uchida
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890 8544, Japan
    J Immunol 186:6945-54. 2011
    ....
  49. ncbi request reprint Syringocystadenoma papilliferum: report of the first case on the lower leg
    Noriko Yoshii
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 31:939-42. 2004
    ..A 26-year-old man had an asymptomatic tumor on his lower leg. Histopathological examination showed it to be a typical SCAP on organoid nevus. This is the first report of SCAP on the lower leg...
  50. ncbi request reprint Syringoma-like eccrine sweat duct proliferation induced by radiation
    Noriko Yoshii
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 33:36-9. 2006
    ..The lesions spread rapidly on her chest during radiation therapy and regressed spontaneously 3 weeks after its completion. We postulate that the lesions were induced by radiation, and promoted by anti-estrogen therapy...
  51. ncbi request reprint Genetic analysis of the ferrochelatase gene in eight Japanese patients from seven families with erythropoietic protoporphyria
    Hiroshi Saruwatari
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kaoshima, Japan
    J Dermatol 33:603-8. 2006
    ..All patients were C/C homozygous for IVS3-48. The allelic frequency of IVS3-48C polymorphism in the healthy Japanese volunteers was 67.8% (103/152)...
  52. doi request reprint Antimicrobial effect of an ultrasonic levitation washer disinfector with silver electrolysis and ozone oxidation on methicillin-resistant Staphylococcus aureus
    Mariko Tamai
    Department of Dermatology, Field of Sensory Organology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 40:1020-6. 2013
    ..Levitation with Ag(+) and O3 may be a valuable tool for treating MRSA infestation of the skin and for accelerating wound healing...
  53. doi request reprint Granulocyte and monocyte adsorption apheresis for Behçet's disease in a pregnant woman
    Yuko Higashi
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 40:1042-4. 2013
    ..There were no complications or adverse effects during her pregnancy and delivery. The neonate manifested no abnormalities. ..
  54. doi request reprint Transdermal nicotine patches for eosinophilic pustular folliculitis
    Asuka Yoshifuku
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 40:711-4. 2013
    ..In the other two patients, the lesions remained unchanged. No severe adverse effects were observed. Our results suggest that transdermal nicotine patches may be useful and safe in the treatment of EPF. ..
  55. doi request reprint Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancy
    Yuki Ichimura
    School of Medicine, Kanazawa University, Kanazawa, Japan
    Ann Rheum Dis 71:710-3. 2012
    ..Recent studies have shown that anti-NXP2 antibody (Ab) is a major MSA in juvenile dermatomyositis (JDM). In this study the frequencies and clinical associations of anti-NXP2 Ab were evaluated in adult patients with IIM...
  56. pmc Unusual anogenital apocrine tumor resembling mammary-like gland adenoma in male perineum: a case report
    Kazuhito Hatanaka
    Department of Molecular and Cellular Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8544, Japan
    Diagn Pathol 5:42. 2010
    ....
  57. ncbi request reprint Crusted scabies in an adult T-cell leukemia/lymphoma patient successfully treated with oral ivermectin
    Kentaro Yonekura
    Department of Hematology, Imamura Bun in Hospital, Kagoshima, Japan
    J Dermatol 33:139-41. 2006
    ..While ivermectin may be useful for treating intractable scabies, attention must be paid to the possible appearance of ivermectin-resistant mites...
  58. ncbi request reprint Bidens pilosa suppresses interleukin-1beta-induced cyclooxygenase-2 expression through the inhibition of mitogen activated protein kinases phosphorylation in normal human dermal fibroblasts
    Nobuyo Yoshida
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Dermatol 33:676-83. 2006
    ..The physiological activities and clinical effectiveness of BP observed under diverse conditions may be partly attributable to its ability to inhibit MAPK, mainly p38, activity, COX-2 expression, and subsequent PGE(2) production...
  59. ncbi request reprint Pseudoxanthoma elasticum (PXE)-like calcification in adult dermatomyositis
    Akiyo Gushi
    Department of Dermatology, Kagoshima University Faculty of Medicine, Japan
    J Dermatol 29:423-6. 2002
    ..The calcification clinically disappeared without any specific treatment except for prednisolone and cyclophosphamide...
  60. ncbi request reprint A case of antiepiligrin cicatricial pemphigoid with nephrotic syndrome
    Yuri Uchino
    Department of Dermatology, Kagoshima University Faculty of Medicine, Kagoshima, Japan
    J Dermatol 31:228-31. 2004
    ..To our knowledge, the association of antiepiligrin cicatricial pemphigoid with nephrotic syndrome has not been reported previously...
  61. doi request reprint NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway
    Atsuko Ibusuki
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Invest Dermatol 134:396-404. 2014
    ..Thus, NKG2D can function as a coactivating stress receptor that directly triggers cytotoxicity in DETCs, at least after priming, via the PI3K-dependent, Syk/ZAP70-independent signaling pathway. ..
  62. doi request reprint Japanese black vinegar "Izumi" inhibits the proliferation of human squamous cell carcinoma cells via necroptosis
    Naoko Baba
    A Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    Nutr Cancer 65:1093-7. 2013
    ..These findings indicate that Izumi inhibits the proliferation of human SCC cells via programmed necrosis (necroptosis). ..
  63. doi request reprint Immunoglobulin G4-positive multi-organ lymphoproliferative syndrome with antiphospholipid antibody syndrome
    Nobuyo Kawakami
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
    J Dermatol 39:636-9. 2012
    ..We made a diagnosis of IgG4(+) -MOLPS with APS. To our knowledge, this complication has not been reported previously...
  64. ncbi request reprint Detection and sequences of human papillomavirus DNA in nongenital seborrhoeic keratosis of immunopotent individuals
    Akiyo Gushi
    Faculty of Medicine, Department of Dermatology, Kagoshima University, 8 35 1, Sakuragaoka, 890 8520, Kagoshima, Japan
    J Dermatol Sci 31:143-9. 2003
    ..In the present study, HPVs were frequently detected from genital lesions or hair follicle in immunocompromised host...
  65. ncbi request reprint The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells
    Shigeto Matsushita
    Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890 8520, Japan
    Int J Oncol 36:1193-200. 2010
    ....
  66. ncbi request reprint A pediatric case of sclerodermatous chronic graft-versus-host disease
    Kenjiro Terasaki
    Department of Dermatology, Kagoshima University, Faculty of Medicine, Kagoshima, Japan
    Pediatr Dermatol 20:327-31. 2003
    ..Furthermore, treating this disease is even more difficult in children. In the future, clarification of the pathogenesis of chronic GVHD and establishment of therapy will be necessary...