Keiichi Okano

Summary

Affiliation: Kagawa Medical University
Country: Japan

Publications

  1. ncbi request reprint Omental flap wrapping with fixation to the cut surface of the liver for reducing delayed gastric emptying after left-sided hepatectomy
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    Surg Today 43:1425-32. 2013
  2. doi request reprint Pancreatic thickness as a predictive factor for postoperative pancreatic fistula after distal pancreatectomy using an endopath stapler
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Surg Today 43:141-7. 2013
  3. doi request reprint Hand-assisted laparoscopic partial splenectomy using an endopath monopolar sealer
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Surg Laparosc Endosc Percutan Tech 21:e291-4. 2011
  4. pmc Hepatic resection for metastatic tumors from gastric cancer
    Keiichi Okano
    First Department of Surgery, Kagawa Medical University, Kagawa, Japan
    Ann Surg 235:86-91. 2002
  5. ncbi request reprint Slow parenchymal flattening technique for distal pancreatectomy using an endopath stapler: simple and safe technical management
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1, Ikenobe, Kita gun, Miki cho, Kagawa 761 0793, Japan
    Hepatogastroenterology 57:1309-13. 2010
  6. pmc 18F-fluorodeoxyglucose positron emission tomography in the diagnosis of small pancreatic cancer
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa 761 0793, Japan
    World J Gastroenterol 17:231-5. 2011
  7. ncbi request reprint (18)F-FDG accumulations in primary malignant melanoma of the esophagus
    Keiichi Okano
    Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Surgery 140:118-9. 2006
  8. doi request reprint Hepatic venous outflow reconstruction using an external iliac vein graft for hepatic malignancies (with video)
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    J Hepatobiliary Pancreat Sci 19:85-90. 2012
  9. ncbi request reprint Lymphocytic infiltration surrounding liver metastases from colorectal cancer
    Keiichi Okano
    First Department of Surgery, Kagawa Medical University, Kagawa, Japan
    J Surg Oncol 82:28-33. 2003
  10. doi request reprint Jun activation domain binding protein 1 is overexpressed from the very early stages of hepatocarcinogenesis
    Shinichi Yachida
    Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Ann Surg Oncol 17:3386-93. 2010

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Omental flap wrapping with fixation to the cut surface of the liver for reducing delayed gastric emptying after left-sided hepatectomy
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    Surg Today 43:1425-32. 2013
    ..The goal of this study was to clarify the clinical implications of an omental flap wrapping procedure that includes fixation to the cut surface of the liver to reduce the incidence of DGE after left-sided hepatectomy...
  2. doi request reprint Pancreatic thickness as a predictive factor for postoperative pancreatic fistula after distal pancreatectomy using an endopath stapler
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Surg Today 43:141-7. 2013
    ..No consistent risk factor has yet been established for the development of pancreatic fistula (PF) after distal pancreatectomy (DP) with a stapler...
  3. doi request reprint Hand-assisted laparoscopic partial splenectomy using an endopath monopolar sealer
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Surg Laparosc Endosc Percutan Tech 21:e291-4. 2011
    ..The hand-assisted laparoscopic approach allows partial splenectomy as a safe and bloodless surgery for select patients...
  4. pmc Hepatic resection for metastatic tumors from gastric cancer
    Keiichi Okano
    First Department of Surgery, Kagawa Medical University, Kagawa, Japan
    Ann Surg 235:86-91. 2002
    ..To assess the surgical results and clinicopathologic features of hepatic metastases from gastric adenocarcinoma to identify patients with a better probability of survival...
  5. ncbi request reprint Slow parenchymal flattening technique for distal pancreatectomy using an endopath stapler: simple and safe technical management
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1, Ikenobe, Kita gun, Miki cho, Kagawa 761 0793, Japan
    Hepatogastroenterology 57:1309-13. 2010
    ..To describe a safer and simple distal pancreatectomy using an endopath stapler, with special emphasis on the slow parenchymal flattening technique...
  6. pmc 18F-fluorodeoxyglucose positron emission tomography in the diagnosis of small pancreatic cancer
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa 761 0793, Japan
    World J Gastroenterol 17:231-5. 2011
    ..To investigate the role of (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the diagnosis of small pancreatic cancer...
  7. ncbi request reprint (18)F-FDG accumulations in primary malignant melanoma of the esophagus
    Keiichi Okano
    Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Surgery 140:118-9. 2006
  8. doi request reprint Hepatic venous outflow reconstruction using an external iliac vein graft for hepatic malignancies (with video)
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    J Hepatobiliary Pancreat Sci 19:85-90. 2012
    ..We present our approach to hepatic venous reconstruction using an external iliac vein (EIV) graft for patients with hepatic malignancies...
  9. ncbi request reprint Lymphocytic infiltration surrounding liver metastases from colorectal cancer
    Keiichi Okano
    First Department of Surgery, Kagawa Medical University, Kagawa, Japan
    J Surg Oncol 82:28-33. 2003
    ..Although several studies reported TILs surrounding metastatic liver tumors, to the authors' knowledge few evaluations of the clinical significance of such features in patients with colorectal liver metastases have been carried out...
  10. doi request reprint Jun activation domain binding protein 1 is overexpressed from the very early stages of hepatocarcinogenesis
    Shinichi Yachida
    Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Ann Surg Oncol 17:3386-93. 2010
    ..Recently, we reported that a high level of p27(Kip1) expression is evident from the very early stages of hepatocarcinogenesis...
  11. doi request reprint Hepatic preconditioning using lipopolysaccharide: association with specific negative regulators of the Toll-like receptor 4 signaling pathway
    Takanori Sano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Transplantation 91:1082-9. 2011
    ..We investigated the molecular mechanism of protection induced by LPS preconditioning against hepatic IRI...
  12. ncbi request reprint [A case of Stage IV AFP producing gastric cancer with long-term survival treated by adjuvant chemotherapy with S-1]
    Takanori Sano
    Dept of Gastroenterological Surgery, Faculty of Medicine, Kagawa University
    Gan To Kagaku Ryoho 37:521-6. 2010
    ..In several cases, however, aggressive treatments for AFP producing gastric cancer may result in a better prognosis. This is a long survival case of AFP producing gastric cancer successfully treated with S-1 after surgery...
  13. doi request reprint A simple and safe pancreas transection using a stapling device for a distal pancreatectomy
    Keiichi Okano
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kida gun, Kagawa 761 0793, Japan
    J Hepatobiliary Pancreat Surg 15:353-8. 2008
    ..These findings support the advantages of using a stapler closure in distal pancreatectomy. This method, using a new stapler device, is considered to be a simple and safe alternative to the standard suture closure technique...
  14. doi request reprint Pilot feasibility study of neoadjuvant chemoradiotherapy with S-1 in patients with locally advanced gastric cancer featuring adjacent tissue invasion or JGCA bulky N2 lymph node metastases
    Tatsushi Inoue
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Ann Surg Oncol 19:2937-45. 2012
    ..Therefore, a prospective trial was conducted to explore the feasibility and safety of NACRT with oral S-1 in a series of cases...
  15. doi request reprint p27(Kip1)is overexpressed in very early stages of hepatocarcinogenesis
    Shinichi Yachida
    Department of Surgery, Kagawa University, Kita gun, Kagawa, Japan
    Cancer Sci 99:2152-9. 2008
    ..In addition, Skp2 expression correlates with tumor dedifferentiation and may contribute to biological aggression in HCC...
  16. doi request reprint Hand-assisted laparoscopic splenectomy for thrombocytopenia in patients with cirrhosis
    Keitaro Kakinoki
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kida gun, Kagawa, 761 0793, Japan
    Surg Today 43:883-8. 2013
    ..The present study evaluated the outcomes of HALS splenectomy for cirrhotic patients...
  17. ncbi request reprint Neutrophil elastase inhibitor (sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery
    Shintaro Akamoto
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kita, Kagawa 761 0793, Japan
    Surg Today 37:359-65. 2007
    ..To examine the effects of the administration of perioperative sivelestat, a selective neutrophil elastase inhibitor, on tumor immunity and inflammatory mediators in patients who undergo major surgery...
  18. ncbi request reprint A patient with unresectable advanced pancreatic cancer achieving long-term survival with gemcitabine chemotherapy
    Yoshiki Okamoto
    Department of Gastroenterological Surgery, Kagawa University, Miki cho, Kita gun, Kagawa 7610793, Japan
    World J Gastroenterol 14:6876-80. 2008
    ..Abdominal CT revealed a complete response (CR) after 3 treatments. Therefore, weekly chemotherapy was stopped and was changed to monthly administration. To date, for 4 years after chemotherapy, the tumor has not reappeared...
  19. ncbi request reprint Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines
    Hisashi Usuki
    First Department of Surgery, Kagawa Medical University, 1750 1 Ikenobe, Miki cho, Kagawa 761 0793, Japan
    Gastric Cancer 6:66-70. 2003
    ..We studied the efficacy of DIF (tegafur + uracil UFT], tegafur + gimeracil + osteracil [S-1 (TS-1)]) relative to DPD activity, with other fluoropyrimidines as controls...
  20. doi request reprint Immunohistochemically detected expression of 3 major genes (CDKN2A/p16, TP53, and SMAD4/DPC4) strongly predicts survival in patients with resectable pancreatic cancer
    Minoru Oshima
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Ann Surg 258:336-46. 2013
    ..The goal of this retrospective study was to clarify the clinical implications of the status of the 3 major genes (CDKN2A/p16, TP53, and SMAD4/DPC4)...
  21. pmc Role of 18F-fluorodeoxyglucose positron emission tomography imaging in surgery for pancreatic cancer
    Hisao Wakabayashi
    Department of Gastroenterological Surgery, Kagawa University, Miki cho, Kita gun, Kagawa 761 0793, Japan
    World J Gastroenterol 14:64-9. 2008
    ....
  22. doi request reprint Attenuation of the systemic inflammatory response and infectious complications after gastrectomy with preoperative oral arginine and omega-3 fatty acids supplemented immunonutrition
    Yoshiki Okamoto
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    World J Surg 33:1815-21. 2009
    ....
  23. doi request reprint Detection of hepatocellular carcinoma using 11C-choline PET: comparison with 18F-FDG PET
    Yuka Yamamoto
    Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan
    J Nucl Med 49:1245-8. 2008
    ..The purpose of this study was to retrospectively investigate the feasibility of 11C-choline PET, compared with 18F-FDG PET, for the detection of hepatocellular carcinoma (HCC)...
  24. doi request reprint Surgical approach for extrahepatic metastasis of HCC in the abdominal cavity
    Takanori Sano
    Department of Surgery, Takamatsu Hospital, Kagawa, Japan
    Hepatogastroenterology 58:2067-70. 2011
    ..Despite recent development of therapeutic strategies for intrahepatic lesions, standard guidelines for treatment of extrahepatic metastases of hepatocellular carcinoma have not been established...
  25. ncbi request reprint The discrepancy in thymidylate synthase and dihydropyrimidine dehydrogenase expression depending on measurement methodologies in stage 4 gastric cancer
    Shintaro Akamoto
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Hepatogastroenterology 55:1882-6. 2008
    ..The aim of this study was to investigate whether there is a discrepancy in the TS and DPD expression depending on measuring method...
  26. ncbi request reprint Application of preoperative portal vein embolization before major hepatic resection in patients with normal or abnormal liver parenchyma
    Hisao Wakabayashi
    First Department of Surgery, Kagawa Medical University, Japan
    Surgery 131:26-33. 2002
    ....
  27. pmc Protective effect of lipopolysaccharide preconditioning in hepatic ischaemia reperfusion injury
    Takanori Sano
    Department of Gastroenterological Surgery, Federation of Public Services and Affiliated Personnel Aid Associations, Takamatsu Hospital, Kagawa, Japan
    HPB (Oxford) 12:538-45. 2010
    ..We examined the liver protective mechanism and correlated signalling pathway of LPS preconditioning in mice...
  28. doi request reprint Extraperitoneal colostomy in laparoscopic abdominoperineal resection using a laparoscopic retractor
    Shintaro Akamoto
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Surg Today 43:580-2. 2013
    ..This paper describes a laparoscopic extraperitoneal sigmoid colostomy using the Endo Retract™ Maxi instrument. This surgical technique is easy, and helps to prevent the development of parastomal hernias...
  29. ncbi request reprint Isolated splenic metastasis of ovarian cancer 20 years after operation: a case report and literature review
    Kunihiko Izuishi
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kita, Kagawa, Japan
    Tumori 96:784-6. 2010
    ..The patient showed no evidence of recurrence until 5 years postoperatively. Splenic metastasis is considered a terminal stage of cancer. However, when the lesion is solitary, surgical treatment is recommended...
  30. doi request reprint Immunohistochemically detected expression of p27(Kip1) and Skp2 predicts survival in patients with intrahepatic cholangiocarcinomas
    Nozomi Hashimoto
    Departments of Gastroenterological Surgery, Kagawa University, Miki cho, Kita gun, Kagawa, Japan
    Ann Surg Oncol 16:395-403. 2009
    ..The results suggest that low p27(Kip1) and high Skp2 expression are associated with aggressive tumor behavior, and these cell-cycle regulators are useful markers to predict outcome of patients with ICC-MF...
  31. ncbi request reprint Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo
    Hisaaki Miyoshi
    Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Int J Oncol 45:322-32. 2014
    ..Our results demonstrate that metformin inhibits the growth of HCC, possibly by inducing G1 cell cycle arrest through the alteration of microRNAs. ..
  32. ncbi request reprint Laparoscopically resected foregut duplication cyst (bronchogenic) of the stomach
    Hisao Wakabayashi
    Department of Gastroenterological Surgery, Kagawa University, Kagawa, Japan
    Dig Dis Sci 52:1767-70. 2007
  33. ncbi request reprint Central venous catheter-related infection diagnosed by CT
    Hisao Wakabayashi
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    Lancet 368:1466. 2006
  34. ncbi request reprint Local expression of tumor necrosis factor-alpha and interleukin-10 on wound healing of intestinal anastomosis during endotoxemia in mice
    Ken Ishimura
    First Department of Surgery, Kagawa Medical University, 1750 1, Ikenobe, Miki, Kita, Kagawa, 761 0793, Japan
    J Surg Res 108:91-7. 2002
    ....
  35. ncbi request reprint Validation of risk assessment scoring systems for an audit of elective surgery for gastrointestinal cancer in elderly patients: an audit
    Hisao Wakabayashi
    Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Int J Surg 5:323-7. 2007
    ..However, if a surgical unit makes appropriate calculations using its own patient series and updates these equations, the POSSUM system can be useful in the risk assessment for surgery in elderly patients...
  36. ncbi request reprint Clinical challenges and images in GI. Image 2. Perforative peritonitis on sclerosing encapsulating peritonitis (abdominal cocoon) in a patient with alcoholic liver cirrhosis
    Hisao Wakabayashi
    Department of Gastroenterological Surgery, Kagawa University, Kagawa, Japan
    Gastroenterology 132:854, 1210. 2007
  37. doi request reprint The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo
    Kiyohito Kato
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Mol Cancer Ther 11:549-60. 2012
    ..The miRNA expression was markedly altered with the treatment of metformin in vitro and in vivo. Various miRNAs altered by metformin also may contribute to tumor growth in vitro and in vivo...
  38. ncbi request reprint Adrenal metastasis from hepatocellular carcinoma through an adrenohepatic fusion
    Keiichi Okano
    J Clin Gastroenterol 38:912. 2004
  39. ncbi request reprint Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver
    Mohammad Akram Hossain
    Kagawa Industry Support Foundation, 2217 16 Hayashi, Takamatsu, Kagawa 761 0301, Japan
    J Biosci Bioeng 101:369-71. 2006
    ..These findings demand further study of the clinical implications of this sugar in view to the advancing fields of liver surgery and transplantation...
  40. doi request reprint Ossifying intramuscular metastases from colon cancer
    Takaaki Yano
    ANZ J Surg 78:516-7. 2008
  41. pmc The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts
    John C Gomez
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Pathol 173:507-17. 2008
    ..The data presented here suggest that Rac2 in hematopoietic cells regulates leukocyte lineage distribution and Rac2 in nonhematopoietic cells might contribute to regulating circulating neutrophil counts...