Genomes and Genes


Hisakazu Iwana


Affiliation: Kagawa University
Country: Japan


  1. Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, et al. Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients. Int J Mol Sci. 2018;19: pubmed publisher
    ..In conclusion, high serum miR-6126 levels during Peg-IFN therapy predicted the HBsAg 1-log drop 48 weeks after the completion of therapy. In vitro assays revealed that miR-6126 was able to suppress HBsAg production and HBV replication. ..
  2. Iwama H, Hori Y, Matsumoto K, Murao K, Ishida T. ReAlignerV: web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequences. BMC Bioinformatics. 2008;9:112 pubmed publisher
    ..ReAlignerV can be accessed through and downloaded from ..
  3. Iwama H, Murao K, Imachi H, Ishida T. Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development. BMC Genomics. 2011;12:228 pubmed publisher
    ..This is the first report showing that the DAR-FFC is a significant network motif. ..
  4. Iwama H. Coordinated networks of microRNAs and transcription factors with evolutionary perspectives. Adv Exp Med Biol. 2013;774:169-87 pubmed publisher
  5. Iwama H, Kato K, Imachi H, Murao K, Masaki T. Human microRNAs originated from two periods at accelerated rates in mammalian evolution. Mol Biol Evol. 2013;30:613-26 pubmed publisher
  6. Fujita K, Iwama H, Oura K, Tadokoro T, Samukawa E, Sakamoto T, et al. Cancer Therapy Due to Apoptosis: Galectin-9. Int J Mol Sci. 2017;18: pubmed publisher
    ..In this review, the molecular characteristics, history and apoptosis-inducing potential of galectin-9 are described. ..