F Yamakura

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. ncbi Effects of substrate analogues and pH on manganese superoxide dismutases
    Leandro C Tabares
    Service de Bioenergetique, DBJC, CNRS URA 2096, CEA Saclay, 91191 Gif sur Yvette, France
    Biochemistry 45:1919-29. 2006
  2. ncbi In vitro preparation of iron-substituted human manganese superoxide dismutase: possible toxic properties for mitochondria
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 1606, Japan
    Free Radic Biol Med 43:423-30. 2007
  3. ncbi Modification of tryptophan and tryptophan residues in proteins by reactive nitrogen species
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, 1 1 Hiragagakuendai, Inba, Chiba 270 1606, Japan
    Nitric Oxide 14:152-61. 2006
  4. ncbi 6-Nitrotryptophan: a specific reaction product of tryptophan residue in human Cu, Zn-SOD treated with peroxynitrite
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 1695, Japan
    Adv Exp Med Biol 527:745-9. 2003
  5. ncbi Pronounced conversion of the metal-specific activity of superoxide dismutase from Porphyromonas gingivalis by the mutation of a single amino acid (Gly155Thr) located apart from the active site
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba 270 1695, Japan
    Biochemistry 42:10790-9. 2003
  6. ncbi Post-translational modifications of superoxide dismutase
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Health Care and Nursing, Japan
    Biochim Biophys Acta 1804:318-25. 2010
  7. ncbi Modification of a single tryptophan residue in human Cu,Zn-superoxide dismutase by peroxynitrite in the presence of bicarbonate
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba, Japan
    Biochim Biophys Acta 1548:38-46. 2001
  8. ncbi A change of the metal-specific activity of a cambialistic superoxide dismutase from Porphyromonas gingivalis by a double mutation of Gln-70 to Gly and Ala-142 to Gln
    B Y Hiraoka
    Department of Oral Biochemistry, Matsumoto Dental University, Shiojiri 399 0781, Japan
    Biochem J 345:345-50. 2000
  9. ncbi Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 16, Japan
    J Biol Chem 273:14085-9. 1998
  10. ncbi Inactivation and destruction of conserved Trp159 of Fe-superoxide dismutase from Porphyromonas gingivalis by hydrogen peroxide
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba, Japan
    Eur J Biochem 253:49-56. 1998

Collaborators

  • K Murayama
  • Shinzaburo Takamiya
  • T Matsumoto
  • S Kudo
  • A Takeya
  • K Uchida
  • Kazuo Kobayashi
  • K Taguchi
  • Eiji Watanabe
  • O Hosomi
  • Y Kubohara
  • T Aoki
  • Saiko Kazuno
  • G G Petsko
  • Sun Un
  • Takaji Fujimura
  • B Yukihiro Hiraoka
  • Muneaki Hashimoto
  • Takehiro Yokota
  • Masaki Osawa
  • Hiroko Kimura
  • Toshiaki Hara
  • Shigetoshi Sugio
  • Yoshitaka Nakajima
  • Keiichi Ikeda
  • Satoshi Furukawa
  • Leandro C Tabares
  • Yukiko Ozawa
  • Daijiro Ohmori
  • Hiroshi Kohno
  • T Imai
  • Nobuko Kon
  • B Y Hiraoka
  • Kimiko Murakami-Murofushi
  • Masahiro Mukaida
  • Kazuko Matsumoto
  • Kazuhiro Yamada
  • Hirohito Sone
  • Masashi Mihara
  • Yuichiro Okubo
  • Rie Hiramatsu
  • Osamu Takikawa
  • Fumihiko Nagase
  • Ken ichi Isobe
  • Tsutomu Kawabe
  • Ken-Ichi Isobe
  • Kenji Takamori
  • Hideaki Iwai
  • Reiko Mineki
  • Hikari Taka
  • Hideoki Ogawa
  • Néstor Cortez
  • Daisuke Yasujima
  • Akio Urushiyama
  • Takeo Imai
  • Takahiro Nakamura
  • Natsu Kamata
  • Hisashi Naito
  • D Ohmori
  • Kazutoshi Minamitani
  • A Urushiyama
  • Y Ogawara
  • H Ikezawa
  • S Sugio
  • K Nakayama
  • T Isobe
  • D Muno
  • T Okuyama
  • Y I Fang

Detail Information

Publications26

  1. ncbi Effects of substrate analogues and pH on manganese superoxide dismutases
    Leandro C Tabares
    Service de Bioenergetique, DBJC, CNRS URA 2096, CEA Saclay, 91191 Gif sur Yvette, France
    Biochemistry 45:1919-29. 2006
    ..coli and the Gly155Thr mutant of the cambialistic SOD from Porphyromonas gingivalis. A model for anion binding and the observed pK involving tyrosine-34 is presented...
  2. ncbi In vitro preparation of iron-substituted human manganese superoxide dismutase: possible toxic properties for mitochondria
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 1606, Japan
    Free Radic Biol Med 43:423-30. 2007
    ....
  3. ncbi Modification of tryptophan and tryptophan residues in proteins by reactive nitrogen species
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, 1 1 Hiragagakuendai, Inba, Chiba 270 1606, Japan
    Nitric Oxide 14:152-61. 2006
    ....
  4. ncbi 6-Nitrotryptophan: a specific reaction product of tryptophan residue in human Cu, Zn-SOD treated with peroxynitrite
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 1695, Japan
    Adv Exp Med Biol 527:745-9. 2003
    ..Among these new peptides, the peptide C showed thesame visible absorption spectrum as that of 6-nitrotryptophan. We conclude 6-nitrotryptophan is one of the reaction products between tryptophan residue in Cu, Zn-SOD and peroxynitrite...
  5. ncbi Pronounced conversion of the metal-specific activity of superoxide dismutase from Porphyromonas gingivalis by the mutation of a single amino acid (Gly155Thr) located apart from the active site
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba 270 1695, Japan
    Biochemistry 42:10790-9. 2003
    ..A possible contribution of the structural differences to the conversion of the metal-specific activity through rearrangement of the hydrogen bond network among Trp123, Gln70, Tyr35, and the metal-coordinated solvent is discussed...
  6. ncbi Post-translational modifications of superoxide dismutase
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Health Care and Nursing, Japan
    Biochim Biophys Acta 1804:318-25. 2010
    ..Finally we briefly introduce a metal insertion system of SOD, focusing particularly on the iron misincorporation of nSOD, as a part of post-translational modifications...
  7. ncbi Modification of a single tryptophan residue in human Cu,Zn-superoxide dismutase by peroxynitrite in the presence of bicarbonate
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba, Japan
    Biochim Biophys Acta 1548:38-46. 2001
    ....
  8. ncbi A change of the metal-specific activity of a cambialistic superoxide dismutase from Porphyromonas gingivalis by a double mutation of Gln-70 to Gly and Ala-142 to Gln
    B Y Hiraoka
    Department of Oral Biochemistry, Matsumoto Dental University, Shiojiri 399 0781, Japan
    Biochem J 345:345-50. 2000
    ..We conclude that a difference in configuration of the Gln residues of P. gingivalis SOD partially accounts for the metal-specific activity of the enzyme...
  9. ncbi Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 16, Japan
    J Biol Chem 273:14085-9. 1998
    ..We found that tyrosine 34 of the enzyme was exclusively nitrated to 3-nitrotyrosine by peroxynitrite. This residue is located near manganese and in a substrate O-2 gateway in Mn-SOD...
  10. ncbi Inactivation and destruction of conserved Trp159 of Fe-superoxide dismutase from Porphyromonas gingivalis by hydrogen peroxide
    F Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba, Japan
    Eur J Biochem 253:49-56. 1998
    ....
  11. ncbi Nitrated and oxidized products of a single tryptophan residue in human Cu,Zn-superoxide dismutase treated with either peroxynitrite-carbon dioxide or myeloperoxidase-hydrogen peroxide-nitrite
    Fumiyuki Yamakura
    Department of Chemistry, Juntendo University School of Medicine, Inba, Chiba 270 1695
    J Biochem 138:57-69. 2005
    ..The tryptophan residue in the modified human Cu,Zn-superoxide dismutase gave the same spectra for the products including 6-nitrotryptophan as the major nitrated product with the two different modification systems...
  12. ncbi Conversion of the metal-specific activity of Escherichia coli Mn-SOD by site-directed mutagenesis of Gly165Thr
    Masaki Osawa
    Department of Hard Tissue Research, Graduate School of Oral Medicine, Matsumoto Dental University, Shiojiri 3990781, Japan
    Biochim Biophys Acta 1804:1775-9. 2010
    ..It was concluded that Gly at position 165 plays a catalytic role in maintaining the integrity of the metal specificity of Mn-SOD...
  13. ncbi Ascaris suum NADH-methemo(myo)globin reductase systems recovering differential functions of hemoglobin and myoglobin, adapting to environmental hypoxia
    Shinzaburo Takamiya
    Department of Molecular and Cellular Parasitology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Parasitol Int 58:278-84. 2009
    ..Differential roles of A. suum perienteric hemoglobin and body wall myoglobin are also discussed from the viewpoint of oxygen homeostasis under hypoxic conditions...
  14. ncbi Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension
    Hiroko Kimura
    Department of Forensic Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Clin Exp Hypertens 32:407-15. 2010
    ..Endurance exercise showed a possible suppressing effect on the arteriosclerosis development by reducing oxidative stress, even after emergence of hypertension...
  15. ncbi Characterization and cloning of an extremely thermostable, Pyrococcus furiosus-type 4Fe ferredoxin from Thermococcus profundus
    T Imai
    Department of Chemistry, College of Science, Rikkyo St Paul s University, Toshima ku, Tokyo 171 8501, Japan
    J Biochem 130:649-55. 2001
    ..Both the anaerobically- and aerobically-purified ferredoxins were found to function as electron acceptors for the pyruvate-ferredoxin oxidoreductase purified from the same archaeon...
  16. ncbi Ascaris suum cytochrome b5, an adult-specific secretory protein reducing oxygen-avid ferric hemoglobin
    Muneaki Hashimoto
    Department of Molecular and Cellular Parasitology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Arch Biochem Biophys 471:42-9. 2008
    ..Therefore, our findings suggest that Ascaris cytochrome b5 is a key redox partner of Ascaris hemoglobin, which acts as an antioxidant...
  17. ncbi Novel oligosaccharide has suppressive activity against human leukemia cell proliferation
    O Hosomi
    Department of Health Science, Juntendo University, Inba gun, Inba mura, Chiba, Japan
    Glycoconj J 26:189-98. 2009
    ..3 kDa) isoform protein (30.8 kDa). The hnRNP A1 protein was also detected from the eluate(s) of the MelNH-agarose column by the immunological method (anti-hnRNP-A1 and HRP-labeled anti-mouse IgG (gamma) antibodies)...
  18. ncbi Amino acid sequence of iron-superoxide dismutase from Pseudomonas ovalis
    T Isobe
    Department of Chemistry, Faculty of Science, Tokyo Metropolitan University, Japan
    FEBS Lett 223:92-6. 1987
    ..The sequence information of the P. ovalis dismutase will facilitate refinement of the X-ray crystallographic data that are now available at 2.9 A resolution...
  19. ncbi Application of the TORO technique of 1H NMR to the structural analysis of cyclic peptide isomers having a slightly distorted symmetry from C2
    Eiji Watanabe
    Department of Chemistry, Rikkyo St Paul s University, Toshima ku, Tokyo 171 8501, Japan
    Magn Reson Chem 42:49-54. 2004
    ..This technique is generally applicable for distinguishing overlapped signals of alpha- and amide protons from the main chains of peptides...
  20. ncbi Contribution of nitric oxide, angiotensin II and superoxide dismutase to exercise-induced attenuation of blood pressure elevation in spontaneously hypertensive rats
    Hiroshi Kohno
    School of Health and Sports Science, Juntendo University School of Medicine, Chiba, Japan
    Jpn Heart J 43:25-34. 2002
    ..We conclude that the combination of these effects with the increased NO formation resulted in the low blood pressure seen in the exercised rats...
  21. ncbi A new assignment technique of 2D-NMR spectra by spin-lock sequence to a tripeptide containing tryptophan in water
    Eiji Watanabe
    Department of Chemistry, Rikkyo University, Toshima ku, Tokyo 171 8501, Japan
    Magn Reson Chem 48:205-9. 2010
    ....
  22. ncbi Manganese(II) zero-field interaction in cambialistic and manganese superoxide dismutases and its relationship to the structure of the metal binding site
    Sun Un
    Service de Bioenergetique, DBJC, CNRS URA 2096, CEA Saclay, 91191 Gif sur Yvette, France
    J Am Chem Soc 126:2720-6. 2004
    ..The relationship between the Mn(II) zero-field interaction and structure of the metal binding site is also discussed...
  23. ncbi Diazotization of kynurenine by acidified nitrite secreted from indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells
    Toshiaki Hara
    Department of Medical Technology, Nagoya University School of Health Sciences, Nagoya, Aichi, Japan
    J Immunol Methods 332:162-9. 2008
    ..An analysis by mass spectrometry showed the new compound to be a diazotization form of Kyn. In conclusion, the deproteinization of samples by acidic treatment should be avoided for the Kyn assay when NO is produced...
  24. ncbi Unique structure of Ascaris suum b5-type cytochrome: an additional alpha-helix and positively charged residues on the surface domain interact with redox partners
    Takehiro Yokota
    Science and Technology Office, Yokohama Center, Mitsubishi Chemical Corporation, 1000 Kamoshida-cho, Aoba, Yokohama 227-8502, Japan
    Biochem J 394:437-47. 2006
    ..suum cytochrome b5 is present in the nematode hypodermis. Based on this histochemical and structural information, the physiological function of A. suum cytochrome b5 and its interaction with nematode metmyoglobin can be hypothesized...
  25. ncbi Detection of 6-nitrotryptophan in proteins by Western blot analysis and its application for peroxynitrite-treated PC12 cells
    Keiichi Ikeda
    The Institute for Environmental and Gender specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279 0021, Japan
    Nitric Oxide 16:18-28. 2007
    ....
  26. ncbi Thermococcus profundus 2-ketoisovalerate ferredoxin oxidoreductase, a key enzyme in the archaeal energy-producing amino acid metabolic pathway
    Yukiko Ozawa
    Department of Life Science and Graduate School of Life Science, and Department of Chemistry and Graduate School of Chemistry, Rikkyo (St. Paul's) University, Toshima-ku, Tokyo 171-8501, Japan
    J Biochem (Tokyo) 137:101-7. 2005
    ....