Hiromichi Tsurui

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Seven-color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition
    H Tsurui
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Histochem Cytochem 48:653-62. 2000
  2. ncbi request reprint Prediction of T-cell epitope
    Hiromichi Tsurui
    Department of Pathology, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    J Pharmacol Sci 105:299-316. 2007
  3. ncbi request reprint IL-4Ralpha polymorphism in regulation of IL-4 synthesis by T cells: implication in susceptibility to a subset of murine lupus
    Wakana Shiroiwa
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Int Immunol 19:175-83. 2007
  4. doi request reprint Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic element for murine systemic lupus erythematosus
    Qingshun Lin
    Department of Pathology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Autoimmun 34:356-63. 2010
  5. ncbi request reprint Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus
    Qingshun Lin
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Immunol 177:1646-54. 2006
  6. doi request reprint Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice
    Shinya Kawano
    Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Eur J Immunol 43:770-8. 2013
  7. ncbi request reprint Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in systemic lupus erythematosus pathogenesis
    Kazuyuki Tsukamoto
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Immunol 180:4530-9. 2008
  8. ncbi request reprint Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Mol Biol 363:345-54. 2006
  9. ncbi request reprint Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus
    Na Li
    Second Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Hum Mol Genet 13:171-9. 2004
  10. ncbi request reprint Transgene-mediated hyper-expression of IL-5 inhibits autoimmune disease but increases the risk of B cell chronic lymphocytic leukemia in a model of murine lupus
    Xiangshu Wen
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Eur J Immunol 34:2740-9. 2004

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Seven-color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition
    H Tsurui
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Histochem Cytochem 48:653-62. 2000
    ..Analyses of mouse thymic tissues stained with seven different fluorescent dyes provided clear independent images, and any combination of two or three individual dye images could be used for constructing multicolor images...
  2. ncbi request reprint Prediction of T-cell epitope
    Hiromichi Tsurui
    Department of Pathology, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    J Pharmacol Sci 105:299-316. 2007
    ....
  3. ncbi request reprint IL-4Ralpha polymorphism in regulation of IL-4 synthesis by T cells: implication in susceptibility to a subset of murine lupus
    Wakana Shiroiwa
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Int Immunol 19:175-83. 2007
    ....
  4. doi request reprint Inhibitory IgG Fc receptor promoter region polymorphism is a key genetic element for murine systemic lupus erythematosus
    Qingshun Lin
    Department of Pathology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Autoimmun 34:356-63. 2010
    ..Thus, the Fcgr2b polymorphism is a key genetic element for not only Yaa-related but also Yaa-unrelated lupus...
  5. ncbi request reprint Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus
    Qingshun Lin
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Immunol 177:1646-54. 2006
    ....
  6. doi request reprint Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice
    Shinya Kawano
    Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Eur J Immunol 43:770-8. 2013
    ..Thus, our model is useful to clarify the shared and the disease-specific mechanisms underlying the clinically distinct systemic autoimmune diseases RA and SLE...
  7. ncbi request reprint Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in systemic lupus erythematosus pathogenesis
    Kazuyuki Tsukamoto
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    J Immunol 180:4530-9. 2008
    ..Thus, this NZW allele may be a candidate of the NZW modifiers that act to promote (NZB x NZW)F(1) disease...
  8. ncbi request reprint Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Mol Biol 363:345-54. 2006
    ..Thus, maintaining proper serotonin levels during childhood may be important for mature sensorimotor gating in adulthood...
  9. ncbi request reprint Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus
    Na Li
    Second Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Hum Mol Genet 13:171-9. 2004
    ..Our findings suggest that these polymorphic LTKs cause up-regulation of the PI3K pathway and possibly form one genetic component of susceptibility to abnormal proliferation of self-reactive B cells in SLE...
  10. ncbi request reprint Transgene-mediated hyper-expression of IL-5 inhibits autoimmune disease but increases the risk of B cell chronic lymphocytic leukemia in a model of murine lupus
    Xiangshu Wen
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Eur J Immunol 34:2740-9. 2004
    ..Thus, this model may provide a clue to the pathogenesis of both SLE and B-CLL...
  11. pmc Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic recombination
    Danqing Zhang
    Second Department of Pathology and Atopy Research Center, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    Proc Natl Acad Sci U S A 101:13838-43. 2004
    ..Our mouse models are useful for analyzing the molecular mechanisms by which MHC class II regions regulate the process of autoimmune responses...
  12. pmc CD3 and immunoglobulin G Fc receptor regulate cerebellar functions
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    Mol Cell Biol 27:5128-34. 2007
    ..In the two knockout mice, enhanced paired-pulse facilitation of parallel fiber-Purkinje cell synapses was shared. These results indicate that diverse immune molecules play critical roles in the functional establishment in the cerebellum...
  13. doi request reprint Presumptive role of 129 strain-derived Sle16 locus in rheumatoid arthritis in a new mouse model with Fcγ receptor type IIb-deficient C57BL/6 genetic background
    Aya Sato-Hayashizaki
    Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Arthritis Rheum 63:2930-8. 2011
    ..We undertook this study to examine the effect of the Sle16 locus on autoimmune disease in FcγRIIb-deficient B6 mice...
  14. pmc Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice
    Akiko Okamoto
    Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Immunol 181:5264-71. 2008
    ..These results indicate that autoantigen presentation by splenic phagocytes including macrophages significantly contributes to autoantibody production and disease progression in lupus-prone mice...
  15. ncbi request reprint Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Neurosci 26:530-4. 2006
    ..Considering an involvement of developmental brain disturbance in psychiatric disorders, TPH1 may act specifically on development of 5-HT neurons, and thereby influence behavior later in life...
  16. pmc A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class I that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model
    Shuji Matsuoka
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Exp Med 198:497-503. 2003
    ....
  17. doi request reprint FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone BXSB mice
    Seiichiro Ando
    Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Biochem Biophys Res Commun 394:804-10. 2010
    ..These results suggest that FTY720 ameliorates lupus nephritis by inhibiting the end-stage inflammatory process following IC deposition in glomeruli...
  18. ncbi request reprint Transcriptional regulation of Fcgr2b gene by polymorphic promoter region and its contribution to humoral immune responses
    Yan Xiu
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Immunol 169:4340-6. 2002
    ....
  19. pmc Role of a serotonin precursor in development of gut microvilli
    Kazuhiro Nakamura
    Department of Biosciences, Teikyo University of Science and Technology, Uenohara 409 0193, Japan
    Am J Pathol 172:333-44. 2008
    ..Thus, 5-HTP and serotonin contribute to distinct cell-type-specific functions via common mediators. Our study might create an opportunity to explore the effects of exogenously applied 5-HTP in humans...