K Suda

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. ncbi Duodenal wall cysts may be derived from a ductal component of ectopic pancreatic tissue
    K Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Histopathology 41:351-6. 2002
  2. ncbi Autoimmune pancreatitis can be classified into early and advanced stages
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 33:345-50. 2006
  3. ncbi Histopathologic difference between chronic pancreatitis animal models and human chronic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 28:e86-9. 2004
  4. ncbi Activated perilobular, not periacinar, pancreatic stellate cells contribute to fibrogenesis in chronic alcoholic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    Pathol Int 57:21-5. 2007
  5. ncbi Histopathologic characteristics of autoimmune pancreatitis based on comparison with chronic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 30:355-8. 2005
  6. ncbi Pathogenesis and progression of human pancreatic fibrosis
    K Suda
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Med Electron Microsc 33:200-6. 2000
  7. ncbi Histopathologic and immunohistochemical studies on the mechanism of interlobular fibrosis of the pancreas
    K Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Arch Pathol Lab Med 124:1302-5. 2000
  8. ncbi Pre-existing histological type and developmental mechanism of mucinous noncystic carcinoma of pancreas
    K Suda
    Juntendo University School of Medicine, Department of Pathology 2 1 1 Hongo, Bunkyo ku, Tokyo, Japan
    Pathol Oncol Res 6:125-9. 2000
  9. ncbi Histopathological study on mechanism and background of tumor-forming pancreatitis
    M Takase
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pathol Int 51:349-54. 2001
  10. ncbi Pancreatic ductal myofibroblasts. Proliferative patterns in various pathologic situations
    M Izumi
    Department of Internal Medicine, Jikei University, School of Medicine, Tokyo, Japan
    Virchows Arch 438:442-50. 2001

Detail Information

Publications59

  1. ncbi Duodenal wall cysts may be derived from a ductal component of ectopic pancreatic tissue
    K Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Histopathology 41:351-6. 2002
    ..To clarify the mechanism of origin of duodenal wall cysts in patients with chronic pancreatitis, developing into duodenal stenosis...
  2. ncbi Autoimmune pancreatitis can be classified into early and advanced stages
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 33:345-50. 2006
    ..Here, we propose a pathological staging for AIP lesions...
  3. ncbi Histopathologic difference between chronic pancreatitis animal models and human chronic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 28:e86-9. 2004
    ..We compared the histologic features of some animal models of pancreatic fibrosis/chronic pancreatitis and chronic pancreatitis in humans...
  4. ncbi Activated perilobular, not periacinar, pancreatic stellate cells contribute to fibrogenesis in chronic alcoholic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    Pathol Int 57:21-5. 2007
    ..85% (range 0.90-9.57%; SD, 2.22%). Fibrosis also immunostained positive for collagen types I and III. In conclusion, activated perilobular, not periacinar, pancreatic stellate cell contribute to fibrogenesis in chronic pancreatitis...
  5. ncbi Histopathologic characteristics of autoimmune pancreatitis based on comparison with chronic pancreatitis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 30:355-8. 2005
    ..To clarify the histopathologic characteristics of autoimmune pancreatitis (AIP), based on comparison with both chronic alcoholic pancreatitis (CAP) and chronic obstructive pancreatitis (COP)...
  6. ncbi Pathogenesis and progression of human pancreatic fibrosis
    K Suda
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Med Electron Microsc 33:200-6. 2000
    ..Therefore, myofibroblasts play an important role in both the mechanism and progression of pancreatic fibrosis...
  7. ncbi Histopathologic and immunohistochemical studies on the mechanism of interlobular fibrosis of the pancreas
    K Suda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Arch Pathol Lab Med 124:1302-5. 2000
    ..To elucidate the mechanism of interlobular fibrosis of the pancreas, which is categorized as chronic alcoholic pancreatitis...
  8. ncbi Pre-existing histological type and developmental mechanism of mucinous noncystic carcinoma of pancreas
    K Suda
    Juntendo University School of Medicine, Department of Pathology 2 1 1 Hongo, Bunkyo ku, Tokyo, Japan
    Pathol Oncol Res 6:125-9. 2000
    ..These two pre-existing types of MC involved mucin overproduction and mucinous degeneration. MUC immunoreactivity in MC revealed three patterns, which may be related to variable outcomes...
  9. ncbi Histopathological study on mechanism and background of tumor-forming pancreatitis
    M Takase
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pathol Int 51:349-54. 2001
    ....
  10. ncbi Pancreatic ductal myofibroblasts. Proliferative patterns in various pathologic situations
    M Izumi
    Department of Internal Medicine, Jikei University, School of Medicine, Tokyo, Japan
    Virchows Arch 438:442-50. 2001
    ..In conclusion, proliferation of myofibroblasts plays an important role in ductal changes in various pathological situations...
  11. ncbi Role of fibrosis-related genes and pancreatic duct obstruction in rat pancreatitis models: implications for chronic pancreatitis
    M Miyauchi
    Department of Pathology, Juntendo University School of Medicine, Bunkyo ku, Tokyo, Japan
    Histol Histopathol 22:1119-27. 2007
    ..Gene expressions of prolyl hydroxylase and tissue inhibitors of matrix metalloproteinase-2 were elevated...
  12. ncbi COX-2+ myofibroblasts may play a key role in marked stromal fibrosis in strictured colorectal carcinomas
    S Kasamaki
    Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Histopathology 44:445-52. 2004
    ..To elucidate the mechanism of marked stromal fibrosis in strictured colorectal carcinomas (SC) that cause complete ileus...
  13. ncbi Small vessel vasculitis limited to pleuropulmonary manifestations, possibly induced by endotoxin
    T Kumasaka
    Department of Pathology I, School of Medicine, Juntendo University, Tokyo, Japan
    Histopathology 43:189-93. 2003
    ..We investigated a rare case of small vessel vasculitis (SVV) limited to pleuropulmonary manifestations, possibly induced by endotoxin, to determine the activation of immuno-mediated cells and endothelia in the pleuropulmonary circulation...
  14. ncbi Periacinar collagenization in patients with chronic alcoholism
    J Kuroda
    Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Pathol Int 48:857-68. 1998
    ....
  15. ncbi Detection of tumor cells in blood using CD45 magnetic cell separation followed by nested mutant allele-specific amplification of p53 and K-ras genes in patients with colorectal cancer
    H Iinuma
    Second Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan
    Int J Cancer 89:337-44. 2000
    ..Our results suggest that the method may be useful for reliable detection of tumor cells circulating in the blood and may help to identify patients at high risk for relapse...
  16. ncbi Monotypic epithelioid angiomyolipoma of the liver
    S Yamasaki
    Department of First Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Histopathology 36:451-6. 2000
    ..We report here the first case of monotypic epithelioid angiomyolipoma arising in the liver...
  17. ncbi Induction of pancreatic islet cell tumors in rats by repeated intravenous administration of 4-hydroxyaminoquinoline 1-oxide
    T Imazawa
    Division of Pathology, National Institute of Health Sciences, Tokyo, Japan
    Toxicol Pathol 29:320-7. 2001
    ..Thus our results indicate that repeated intravenous administration of 4HAQO to rats is useful for the induction of islet cell tumors at high incidence...
  18. ncbi Involvement of vacuolar H+ -ATPase in incorporation of risedronate into osteoclasts
    M Takami
    Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan
    Bone 32:341-9. 2003
    ....
  19. ncbi Isolated necrotizing arteritis (localized polyarteritis nodosa): examination of the histological process and disease entity based on the histological classification of stage and histological differences from polyarteritis nodosa
    Toshiharu Matsumoto
    First Department of Pathology, Juntendo University, Tokyo 113 8421, Japan
    Cardiovasc Pathol 16:92-7. 2007
    ..Therefore, we examined the disease entity of INA based on the histological comparison of both diseases. In addition, a histological classification of INA, in which the histological process of INA is included, was described...
  20. ncbi Multilocular thymic cyst associated with follicular hyperplasia: clinicopathologic study of 4 resected cases
    Hiroshi Izumi
    Department of First Pathology, Juntendo University, School of Medicine, Tokyo 113 8421, Japan
    Hum Pathol 36:841-4. 2005
    ..The pathological findings, together with clinical courses of our cases, suggest that inflammation accompanied by autoimmune diseases may play, in part, an important role in the development of MTCs...
  21. ncbi Lymphangiogenesis-mediated shedding of LAM cell clusters as a mechanism for dissemination in lymphangioleiomyomatosis
    Toshio Kumasaka
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Am J Surg Pathol 29:1356-66. 2005
    ....
  22. ncbi Pancreatic, hepatic, splenic, and mesenteric mucinous cystic neoplasms (MCN) are lumped together as extra ovarian MCN
    Saori Shiono
    First Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pathol Int 56:71-7. 2006
    ..In conclusion, MCN in various organs should be lumped together as 'extra ovarian' MCN. The OLS was identified on the basis of myofibroblastic proliferation both in response to neoplastic development and dependent on hormones...
  23. ncbi Expression of transforming growth factor beta1, beta2, and beta3 in chronic, cancer-associated, obstructive pancreatitis
    Yuki Fukumura
    Department of Pathology I, Juntendo University, School of Medicine, Tokyo, Japan
    Arch Pathol Lab Med 130:356-61. 2006
    ..The potent fibrogenic capacities of transforming growth factor betas (TGF-betas) have been emphasized in vitro and in animal studies. However, the roles of TGF-betas in human chronic pancreatitis have not been fully clarified...
  24. ncbi Human papillomavirus localization in cervical adenocarcinoma and adenosquamous carcinoma using in situ polymerase chain reaction: review of the literature of human papillomavirus detection in these carcinomas
    Kanako Ogura
    Department of Pathology I, School of Medicine, Juntendo University, Tokyo, Japan
    Pathol Int 56:301-8. 2006
    ..HPV infection in the underlying squamous epithelium might be related to the carcinogenesis, even in cervical adenocarcinoma. HPV-DNA localization was different in each component of adenosquamous carcinoma...
  25. ncbi Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal
    Kazuichi Okazaki
    The Third Department of Internal Medicine, Kansai Medical University, Moriguchi, Japan
    J Gastroenterol 41:626-31. 2006
  26. ncbi Expression of transforming growth factor beta by small duct epithelium in chronic, cancer-associated, obstructive pancreatitis: an in situ hybridization study and review of the literature
    Yuki Fukumura
    Department of Pathology I, School of Medicine, Juntendo University, Hongo, Bunkyo ku, Tokyo, Japan
    Pancreas 35:353-7. 2007
    ..The objective of this study was to identify cellular sources of TGF-beta mRNA and compare the results with previous immunohistochemical/in situ hybridization studies...
  27. ncbi Review of the cytologic features of noninvasive ductal carcinomas of the pancreas: differences from invasive ductal carcinoma
    Hitoshi Hara
    Division of Pathology, Clinical Laboratory, Yamanashi Prefectural Central Hospital, Japan
    Am J Clin Pathol 129:115-29. 2008
    ..To preoperatively differentiate noninvasive IPMC and PanIN-3 from IDAP, these features would be clinically very useful...
  28. ncbi Intraductal carcinoma with complex fusion of tubular glands without macroscopic mucus in main pancreatic duct: dilemma in classification
    Takeshi Hisa
    Department of Internal Medicine, Saku Central Hospital, Nagano, Japan
    Pathol Int 57:741-5. 2007
    ....
  29. ncbi A clinicopathological and immunohistochemical comparison of squamous cell carcinoma arising in scars versus nonscar SCC in Japanese patients
    Akiko Ueda
    First Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Am J Dermatopathol 28:472-7. 2006
    ..In this study, the follow-up time was short and the number of patients was small, and for these reasons it might not have been possible to obtain evidence that scar carcinoma is aggressive...
  30. ncbi Histopathological study of invasive ductal carcinoma (IDC) of the pancreas without associated cancerous occlusion of the main pancreatic duct
    Yoshiki Naito
    Department of Pathology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan
    J Hepatobiliary Pancreat Surg 13:556-61. 2006
    ..CONCLUSIONS: Our findings suggested that these two types of IDC could have different biological features...
  31. ncbi Invasive ductal adenocarcinoma of the pancreas may originate from the larger pancreatic duct: a study of 13 tumors less than 2 cm in diameter
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Tokyo 113 8421, Japan
    J Hepatobiliary Pancreat Surg 14:283-8. 2007
    ..We aimed to elucidate the origin/primary site of invasive ductal adenocarcinoma of the pancreas, based on the distribution of intraductal carcinoma components. These components were identified by a mural elastic fiber cuff...
  32. ncbi Different patterns of p16INK4A and p53 protein expressions in intraductal papillary-mucinous neoplasms and pancreatic intraepithelial neoplasia
    Keiko Abe
    Department of Pathology I, Juntendo University School of Medicine, Tokyo, Japan
    Pancreas 34:85-91. 2007
    ..To examine aberrations and differences of cell cycle regulatory proteins between intraductal papillary-mucinous neoplasms (IPMNs) and pancreatic intraepithelial neoplasias (PanINs)...
  33. ncbi [The relationship with human papilloma virus DNA in cervical adenocarcinoma]
    Kanako Ogura
    Department of Pathology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo 113-8421
    Rinsho Byori 52:115-9. 2004
    ..Therefore, HPV infection plays a very important role in not only squamous cell carcinoma but also adenocarcinoma in uterine cervix...
  34. ncbi Pleomorphic adenoma in nasal cavity: immunohistochemical study of three cases
    Shu Hirai
    First Department of Pathology, Juntendo University, School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Auris Nasus Larynx 29:291-5. 2002
    ..Therefore, immunoreactivity of the tumor cells were the same among the intranasal pleomorphic adenoma having various histological components...
  35. ncbi Adult-onset familial pulmonary fibrosis in Japanese brothers
    Yasuko Yoshioka
    Department of Respiratory Medicine, Juntendo University, School of Medicine, Tokyo, Japan
    Pathol Int 54:41-6. 2004
    ..It is necessary to clarify the presence of novel gene mutations of SP-C or other genes to explain these particular pathological findings and the low DLCO observed in this family...
  36. ncbi Intraductal spread of pancreatic cancer. Clinicopathologic study of 54 pancreatectomized patients
    Shigetaka Yamasaki
    First Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Pancreatology 2:407-12. 2002
    ..Invasive ductal adenocarcinoma of the pancreas (IDAP) also spreads through the pancreatic ductal tree. The aim of this study was to clarify the clinicopathologic features of IDAP with intraductal spread...
  37. ncbi alpha-Smooth muscle actin immunoreactivity may change in nature in interlobular fibrosis of the pancreas in patients with congenital biliary dilatation
    Kenro Matsubara
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pathol Int 54:498-502. 2004
    ..In conclusion, biliary pancreatitis is not likely to evolve into chronic pancreatitis/more progressive state because 'pre-existing'alpha-SMA immunoreactivity in the interlobular area may change in nature...
  38. ncbi Carcinosarcoma of the esophagus characterized by myoepithelial and ductal differentiations
    Masahiko Ohtaka
    Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Pathol Int 52:657-63. 2002
    ..The histogenesis of this tumor may be associated with a totipotent stem cell of esophageal mucosa, which has the potential to differentiate into squamous cells, ductal cells or myoepithelial cells...
  39. ncbi Uterine tumors resembling ovarian sex-cord tumors producing parathyroid hormone-related protein of the uterine cervix
    Chikako Suzuki
    First Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Pathol Int 52:164-8. 2002
    ..Furthermore, in this tumor, production of PTH-rP was demonstrated by normalization of serum PTH-rP after the tumorectomy and immunoreactivity for PTH-rP in the tumor cells...
  40. ncbi Lymphangiogenesis in lymphangioleiomyomatosis: its implication in the progression of lymphangioleiomyomatosis
    Toshio Kumasaka
    Department of Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 13 8421, Japan
    Am J Surg Pathol 28:1007-16. 2004
    ..Our study is likely to provide a novel point of view on the pathophysiologic significance of lymphangiogenesis in LAM...
  41. ncbi New criterial for cytologic diagnosis of adenoid cystic carcinoma
    Hitoshi Hara
    Department of Biochemistry, Akebono Medical Welfare Center, and Pathology Division, Yamanashi Prefectural Central Hospital, Yamanashi, Japan
    Acta Cytol 49:43-50. 2005
    ..To formulate new criteria for adenoid cystic carcinoma (ADCC)...
  42. ncbi Distended glands or overreplacement of ampullary mucosa at the papilla of Vater
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan
    J Hepatobiliary Pancreat Surg 11:260-5. 2004
    ..They may represent not only malignant change but also an adaptive phenomenon for bile and pancreatic juice flow...
  43. ncbi Case of combined adrenal cortical adenoma and myelolipoma
    Takaharu Matsuda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pathol Int 54:725-9. 2004
    ..We discuss the etiology of myelolipoma and suggest that myelolipoma can develop in the course of endocrine hyperfunction...
  44. ncbi Pathology of autoimmune pancreatitis and tumor-forming pancreatitis
    Koichi Suda
    Department of Human Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 113 8421, Japan
    J Gastroenterol 42:22-7. 2007
    ..These tumorous lesions may be changeable along the disease process...
  45. ncbi Does ampullary carcinoma arise from distended glands in the papilla of Vater?
    Hiroshi Sonoue
    Department of Human Pathology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Hepatobiliary Pancreat Surg 15:161-8. 2008
    ..Glands near the surface of the papilla of Vater may become distended with mucus and become hyperplastic; that is, become distended. In this study, we tried to clarify carcinogenesis in these distended glands...
  46. ncbi Distribution of intraductal lesions in small invasive ductal carcinoma of the pancreas
    Takeshi Hisa
    Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Pancreatology 7:341-6. 2007
    ..To investigate the distribution of intraductal lesions in small invasive ductal carcinoma (IDC) of the pancreas...
  47. ncbi Peritoneal endometriosis in the broad ligament presenting as a large tumor
    Tomoko Itoga
    Department of Obstetrics and Gynecology, Juntendo University, School of Medicine, Tokyo, Japan
    Pathol Int 52:410-5. 2002
    ..In conclusion, this case is rare, but it is important for pathologists to be aware of the phenomenon (that extensive peritoneal endometriosis produces a large tumor) in the histological diagnosis of a tumor in the peritoneum...
  48. ncbi Growth process of small pancreatic carcinoma: a case report with imaging observation for 22 months
    Takeshi Hisa
    Department of Internal Medicine, Saku Central Hospital, 197 Usuda, Saku, Nagano 384 0301, Japan
    World J Gastroenterol 14:1958-60. 2008
    ..The tumor volume doubling time was 252 d. The Ki67 labeling index was 15.9%, similar to that described in previous reports. Hence, IDC may grow slowly while remaining small...
  49. ncbi Cytologic study of noninvasive intraductal papillary-mucinous carcinoma of the pancreas
    Hitoshi Hara
    Department of Biochemistry, Akebono Medical Welfare Center, Pathology Division, Yamanashi Prefectural Central Hospital, Yamanashi, Japan
    Acta Cytol 46:519-26. 2002
    ..Furthermore, the addition of clearly defined cell borders and euchromatin and the presence of some goblet cells are more strongly suggestive of noninvasive IPMC...
  50. ncbi [Pathology of intraductal papillary-mucinous tumor of the pancreas]
    Bunsei Nobukawa
    Department of Pathology (I, Juntendo University School of Medicine, Tokyo, Japan
    Nippon Geka Gakkai Zasshi 104:439-42. 2003
    ..In future, differences and/or similarities will be discussed on the basis of molecular analyses of the carcinogensis of both tumors...
  51. ncbi Two cytologic patterns in invasive ductal adenocarcinoma of the pancreas
    Hitoshi Hara
    Department of Biochemistry, Akebono Medical Welfare Center, Nirasaki City, Japan
    Acta Cytol 49:611-20. 2005
    ..To clarify 2 cytologic patterns: severe ductal dysplasia (SD)/carcinoma in situ (CIS) and invasive components of invasive ductal adenocarcinoma of the pancreas (IDAP)...
  52. ncbi Pancreatic segmentation on an embryological and anatomical basis
    Koichi Suda
    Department of Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan
    J Hepatobiliary Pancreat Surg 13:146-8. 2006
    ..These segments are based on the conventional anatomical division of the pancreas, identification of the originating primordium, and distribution of the ventral and dorsal pancreas...
  53. ncbi Intraductal low papillary histological pattern of carcinoma component shows intraductal spread in invasive carcinoma of the pancreas
    Hirofumi Tanase
    Department of Pathology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan
    J Hepatobiliary Pancreat Surg 13:235-8. 2006
    ..CONCLUSIONS: A tubular pattern of intraductal components in IDC of the pancreas indicates intraductal invasion, while a low papillary pattern indicates CIS or carcinoma in another location to which it has spread...
  54. ncbi Relationship between the prostatic tissue components and natural history of benign prostatic hyperplasia
    Takaharu Matsuda
    Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Anal Quant Cytol Histol 28:121-4. 2006
    ..Few reports have been published on the relationship between prostatic tissue components and the natural history of benign prostatic hyperplasia (BPH). The present study was undertaken to evaluate this relationship...
  55. ncbi Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis
    Koichi Suda
    Department of Surgery, School of Medicine, Keio University, Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan
    World J Surg 30:1755-62. 2006
    ..CONCLUSIONS: The present study demonstrates that anti-HMGB1 antibodies are effective in the treatment of severe sepsis in a rat model, thereby supporting the relevance of HMGB1 eradication therapy for severe sepsis...
  56. ncbi Loss of heterozygosity in clonal evolution with genetic progression and divergence in spindle cell carcinoma of the gallbladder
    Atsushi Arakawa
    First Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan
    Hum Pathol 35:418-23. 2004
    ..Furthermore, we showed genetic heterogeneity accompanying the phenotypic divergence, with patterns of genetic alterations that are consistent with both the progression and divergence within the individual tumors...
  57. ncbi Cystic neoplasm of the pancreas: a Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor
    Yutaka Suzuki
    Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan
    Pancreas 28:241-6. 2004
    ..5% in invasive carcinoma cases. In conclusion, IPMT and MCT show distinct clinicopathologic and prognostic differences. The results from this study may contribute to the diagnosis and treatment of IPMT and MCT...
  58. ncbi Prognostic value of CD44 isoform expression in thymic epithelial neoplasms
    Satoshi Sonobe
    Department of General Thoracic Surgery, Juntendo University, School of Medicine, Tokyo, Japan
    Cancer 103:2015-22. 2005
    ..Accordingly, the expression of CD44 isoforms in thymic epithelial neoplasms was investigated using immunohistochemistry to assess their possible value as prognostic indicators...
  59. ncbi G1 arrest and expression of cyclin-dependent kinase inhibitors in tamoxifen-treated MCF-7 human breast cancer cells
    Akira Ichikawa
    Department of Laboratory Medicine, Tochigi Cancer Center, Utsunomiya, and Department of Pathology, Juntendo University School of Medicine, Tokyo, Japan
    Hum Cell 21:28-37. 2008
    ..The proposed mechanism is similar to that underlying the cytotoxic effects of other agents and ionizing irradiation that cause DNA damage...