Akira Matsuda

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. ncbi Basophils in the giant papillae of chronic allergic keratoconjunctivitis
    A Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Br J Ophthalmol 94:513-8. 2010
  2. ncbi Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 51:151-5. 2010
  3. ncbi The role of interleukin-33 in chronic allergic conjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:4646-52. 2009
  4. ncbi Hyperexpression of the high-affinity IgE receptor-beta chain in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:2871-7. 2009
  5. ncbi Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 17:965-70. 2011
  6. ncbi Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts
    Kanji Hori
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1846-51. 2012
  7. ncbi Patterns of aquaporin expression in the canine eye
    Kaoru Karasawa
    Tokyo University of Agriculture and Technology, Tokyo, Japan
    Vet J 190:e72-7. 2011
  8. ncbi Lattice corneal dystrophy type IV (p.Leu527Arg) is caused by a founder mutation of the TGFBI gene in a single Japanese ancestor
    Hideki Fukuoka
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 51:4523-30. 2010
  9. ncbi Role of TGF-β in tissue eosinophilia associated with vernal keratoconjunctivitis
    Kaori Ohtomo
    Department of Ophthalmology, Juntendo University School of Medicine, 3 1 3 Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Exp Eye Res 91:748-54. 2010
  10. ncbi Retinal degeneration and rd1 mutation in NC/Tnd mice-a human atopic dermatitis model
    Kaoru Karasawa
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Curr Eye Res 36:350-7. 2011

Collaborators

Detail Information

Publications29

  1. ncbi Basophils in the giant papillae of chronic allergic keratoconjunctivitis
    A Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Br J Ophthalmol 94:513-8. 2010
    ..The aim of this present study was to analyse the in situ immunolocalisation of basophils and other relevant inflammatory cells in chronic allergic keratoconjunctivitis...
  2. ncbi Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 51:151-5. 2010
    ..This study was undertaken to investigate the expression of TSLP in the giant papillae obtained from patients with vernal keratoconjunctivitis (VKC) or atopic keratoconjunctivitis (AKC), and its functional roles were analyzed...
  3. ncbi The role of interleukin-33 in chronic allergic conjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:4646-52. 2009
    ..Recently, a novel Th2 cytokine, interleukin-33 (IL-33), was discovered to be a specific ligand for ST2L. The authors investigated the role of IL-33 in chronic allergic conjunctivitis...
  4. ncbi Hyperexpression of the high-affinity IgE receptor-beta chain in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:2871-7. 2009
    ....
  5. ncbi Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 17:965-70. 2011
    ..To report two novel mutation of the tumor-associated calcium signal transducer 2 (TACSTD2) gene in 3 Japanese patients with gelatinous drop-like corneal dystrophy (GDLD)...
  6. ncbi Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts
    Kanji Hori
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1846-51. 2012
    ....
  7. ncbi Patterns of aquaporin expression in the canine eye
    Kaoru Karasawa
    Tokyo University of Agriculture and Technology, Tokyo, Japan
    Vet J 190:e72-7. 2011
    ..The observations suggested that several subtypes of the AQP family are involved in the regulation of water homeostasis in the canine eye...
  8. ncbi Lattice corneal dystrophy type IV (p.Leu527Arg) is caused by a founder mutation of the TGFBI gene in a single Japanese ancestor
    Hideki Fukuoka
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 51:4523-30. 2010
    ..Although LCD type I has been reported worldwide, LCD4 has been reported only in the Japanese population. In the present study, a haplotype analysis was performed to investigate whether this LCD subtype is caused by a founder mutation...
  9. ncbi Role of TGF-β in tissue eosinophilia associated with vernal keratoconjunctivitis
    Kaori Ohtomo
    Department of Ophthalmology, Juntendo University School of Medicine, 3 1 3 Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Exp Eye Res 91:748-54. 2010
    ..This effect of TGF-β(1) and IL-4/IL-13 was inhibited by glucocorticoids, but neither by cyclosporine nor by tacrolimus. In conclusion, TGF-β(1) has an important role in the tissue eosinophilia associated with VKC...
  10. ncbi Retinal degeneration and rd1 mutation in NC/Tnd mice-a human atopic dermatitis model
    Kaoru Karasawa
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Curr Eye Res 36:350-7. 2011
    ..The purposes of the current study were to investigate the development of retinal degeneration in NC/Tnd mice...
  11. ncbi Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Am J Pathol 177:1344-55. 2010
    ..These results indicate that loss of function of the TACSTD2 gene impairs epithelial barrier function through decreased expression and altered subcellular localization of tight junction-related proteins in GDLD corneas...
  12. ncbi Interaction Between Conjunctival Epithelial Cells and Mast Cells Induces CCL2 Expression and Piecemeal Degranulation in Mast Cells
    Satoshi Iwamoto
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 54:2465-73. 2013
    ..We examined the roles of interaction between the conjunctival epithelial cells and mast cells...
  13. ncbi Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease
    Noriko Okamoto
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Cardiovasc Res 92:209-17. 2011
    ..In this study, we examined the clinical efficacy of silencing the int6 gene, which encodes a protein that stabilizes hypoxia-inducible factor (HIF)-2α, on angiogenesis in PAD...
  14. ncbi Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing
    Nobuyuki Ebihara
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 52:8549-57. 2011
    ..To investigate the role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing...
  15. ncbi Daily intake of Jeju groundwater improves the skin condition of the model mouse for human atopic dermatitis
    Akane Tanaka
    Laboratories of Comparative Animal Medicine, Tokyo, Japan
    J Dermatol 40:193-200. 2013
    ..The early inflammation and hypersensitivity in the atopic skin was alleviated in mice supplied with Jeju groundwater, suggesting its profitable potential on the daily care of patients with skin troubles including AD...
  16. ncbi Differences in blast immunophenotypes among disease types in myelodysplastic syndromes: a multicenter validation study
    Kiyoyuki Ogata
    Division of Hematology, Department of Medicine, Nippon Medical School, Tokyo, Japan
    Leuk Res 36:1229-36. 2012
    ..Logistic regression analyses showed that, in addition to myeloblast percentages, the expression of CD7 and B7-H1 on myeloblasts was independently associated with AL-MDS patients...
  17. ncbi Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2
    Akane Tanaka
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, 3 5 8 Saiwai cho, Fuchu, Tokyo, Japan
    Am J Physiol Cell Physiol 301:C1360-7. 2011
    ..This is the first study that provides evidence for a novel role of mast cells in adipogenesis via PPARγ activation...
  18. ncbi Investigation of the corneal filament in filamentary keratitis
    Hidetoshi Tanioka
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:3696-702. 2009
    ..In this study, an immunohistochemical technique was used to clarify the exact composition of the corneal filament in filamentary keratitis. In addition, the mechanisms responsible for filament formation were identified...
  19. ncbi High-affinity IgE receptor-beta chain expression in human mast cells
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Immunol Methods 336:229-34. 2008
    ..Upregulation of beta-chain expression with monomeric IgE treatment suggests possible roles of FcepsilonRI-beta protein as an atopy-related molecule...
  20. ncbi Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II
    Hyunho Lee
    Department of Molecular Cell Immunology and Allergology, Nihon University School of Medicine, Tokyo, Japan
    Arthritis Rheum 65:109-19. 2013
    ..However, IgG receptor expression on human synovial MCs remains uncharacterized. The aim of this study was to identify which IgG receptor(s) on synovial MCs are responsible for MC activation in immune complexes...
  21. ncbi Laryngeal preservation in advanced piriform sinus squamous cell carcinomas using superselective intra-arterial chemoradiation therapy with three agents
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan
    Acta Otolaryngol 133:318-26. 2013
    ..Superselective intra-arterial chemotherapy, which enables local control and laryngeal preservation, is a safe and useful therapy for preservation of nutrition, speech, and swallowing functions...
  22. ncbi Perlecan-deficient mutation impairs corneal epithelial structure
    Takenori Inomata
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1277-84. 2012
    ..To elucidate the role of perlecan (Hspg2), a large multidomain heparan sulfate proteoglycan expressed in the basement membrane, in the structure of the corneal epithelium...
  23. ncbi Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 48:583-9. 2007
    ..This study was conducted to examine the genetic association between the atopy-related genes and patients with ocular complications (ocular AD)...
  24. ncbi Superselective intra-arterial chemotherapy for laryngeal preservation in carcinoma of the anterior oropharyngeal wall
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan
    Acta Otolaryngol 133:194-202. 2013
    ..Superselective intra-arterial chemotherapy, which can provide local control and laryngeal preservation, is safe and useful for preserving pharyngeal and laryngeal functions...
  25. ncbi LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population
    Kazuhiko Mori
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 14:1037-40. 2008
    ..We also quantified LOXL1 mRNA expression in the human lens capsule to examine the possible correlation between LOXL1 expression and XFG pathogenesis...
  26. ncbi Peroxisome proliferator-activated receptor γ-mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice
    Kyungsook Jung
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    J Allergy Clin Immunol 127:420-429.e1-6. 2011
    ..Because peroxisome proliferator-activated receptor (PPAR) γ acts as a negative regulator in immune cells, suppressive properties of PPARγ in allergic responses have been proposed...
  27. ncbi Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL: a 36-month analysis of a phase I and II study
    Kensuke Usuki
    Division of Hematology, NTT Kanto Medical Center, 5 9 22 Higashigotanda, Shinagawa ku, Tokyo, Japan
    Int J Hematol 95:409-19. 2012
    ..These results support the favorable long-term efficacy and tolerability of nilotinib in Japanese patients with imatinib-resistant or -intolerant chronic-phase chronic myeloid leukemia...
  28. ncbi Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: a prospective validation study
    Kiyoyuki Ogata
    Division of Hematology, Department of Medicine, Nippon Medical School, Tokyo, Japan
    Haematologica 94:1066-74. 2009
    ..The diagnosis of myelodysplastic syndromes is not always straightforward when patients lack specific diagnostic markers, such as blast excess, karyotype abnormality, and ringed sideroblasts...
  29. ncbi Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium
    Kazuhiko Yoshida
    Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo, Japan
    Invest Ophthalmol Vis Sci 43:364-70. 2002
    ..To examine the expression of the p27(KIP1)in the normal and epithelial-scraped cornea and whether degradation of p27(KIP1)by Skp2 is involved in the regulation of cell proliferation in response to wounding of the corneal epithelium...