Akira Matsuda

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. doi request reprint Basophils in the giant papillae of chronic allergic keratoconjunctivitis
    A Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Br J Ophthalmol 94:513-8. 2010
  2. doi request reprint Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 51:151-5. 2010
  3. doi request reprint The role of interleukin-33 in chronic allergic conjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:4646-52. 2009
  4. doi request reprint Hyperexpression of the high-affinity IgE receptor-beta chain in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:2871-7. 2009
  5. doi request reprint Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy
    Koji Kitazawa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 54:5701-11. 2013
  6. doi request reprint Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells
    Satoshi Iwamoto
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 54:2465-73. 2013
  7. pmc Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 17:965-70. 2011
  8. ncbi request reprint The epithelium takes center stage in allergic keratoconjunctivitis
    Nobuyuki Ebihara
    From the Department of Ophthalmology and Allergy Research Center, Juntendo University School of Medicine, Tokyo, Japan
    Cornea 29:S41-7. 2010
  9. doi request reprint Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts
    Kanji Hori
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1846-51. 2012
  10. doi request reprint Patterns of aquaporin expression in the canine eye
    Kaoru Karasawa
    Tokyo University of Agriculture and Technology, Tokyo, Japan
    Vet J 190:e72-7. 2011

Collaborators

Detail Information

Publications40

  1. doi request reprint Basophils in the giant papillae of chronic allergic keratoconjunctivitis
    A Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Br J Ophthalmol 94:513-8. 2010
    ..The aim of this present study was to analyse the in situ immunolocalisation of basophils and other relevant inflammatory cells in chronic allergic keratoconjunctivitis...
  2. doi request reprint Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 51:151-5. 2010
    ..This study was undertaken to investigate the expression of TSLP in the giant papillae obtained from patients with vernal keratoconjunctivitis (VKC) or atopic keratoconjunctivitis (AKC), and its functional roles were analyzed...
  3. doi request reprint The role of interleukin-33 in chronic allergic conjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:4646-52. 2009
    ..Recently, a novel Th2 cytokine, interleukin-33 (IL-33), was discovered to be a specific ligand for ST2L. The authors investigated the role of IL-33 in chronic allergic conjunctivitis...
  4. doi request reprint Hyperexpression of the high-affinity IgE receptor-beta chain in chronic allergic keratoconjunctivitis
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:2871-7. 2009
    ....
  5. doi request reprint Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy
    Koji Kitazawa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 54:5701-11. 2013
    ..The exact mechanism of this disease has yet to be elucidated. No fundamental treatment exists. This study was conducted to establish an immortalized corneal epithelial cell line to be used as a GDLD disease model...
  6. doi request reprint Interaction between conjunctival epithelial cells and mast cells induces CCL2 expression and piecemeal degranulation in mast cells
    Satoshi Iwamoto
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 54:2465-73. 2013
    ..We examined the roles of interaction between the conjunctival epithelial cells and mast cells...
  7. pmc Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 17:965-70. 2011
    ..To report two novel mutation of the tumor-associated calcium signal transducer 2 (TACSTD2) gene in 3 Japanese patients with gelatinous drop-like corneal dystrophy (GDLD)...
  8. ncbi request reprint The epithelium takes center stage in allergic keratoconjunctivitis
    Nobuyuki Ebihara
    From the Department of Ophthalmology and Allergy Research Center, Juntendo University School of Medicine, Tokyo, Japan
    Cornea 29:S41-7. 2010
    ..To investigate the role of the epithelium in severe allergic conjunctivitis...
  9. doi request reprint Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts
    Kanji Hori
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1846-51. 2012
    ....
  10. doi request reprint Patterns of aquaporin expression in the canine eye
    Kaoru Karasawa
    Tokyo University of Agriculture and Technology, Tokyo, Japan
    Vet J 190:e72-7. 2011
    ..The observations suggested that several subtypes of the AQP family are involved in the regulation of water homeostasis in the canine eye...
  11. doi request reprint Lattice corneal dystrophy type IV (p.Leu527Arg) is caused by a founder mutation of the TGFBI gene in a single Japanese ancestor
    Hideki Fukuoka
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 51:4523-30. 2010
    ..Although LCD type I has been reported worldwide, LCD4 has been reported only in the Japanese population. In the present study, a haplotype analysis was performed to investigate whether this LCD subtype is caused by a founder mutation...
  12. pmc A molecular targeting against nuclear factor-κB, as a chemotherapeutic approach for human malignant mesothelioma
    Sho Nishikawa
    Cooperative Major in Advanced Health Science, Graduate School of Bio Applications and System Engineering, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan
    Cancer Med 3:416-25. 2014
    ..These results indicate that a targeted drug against NF-κB might have therapeutic efficacy in the treatment of human malignant mesothelioma. ..
  13. doi request reprint Production of stem cell factor in canine mast cell tumors
    Yosuke Amagai
    Cooperative Major in Advanced Health Science, Graduate School of Bio Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Res Vet Sci 96:124-6. 2014
    ..These results indicate the broad contribution of SCF autocrine/paracrine mechanism on clinical MCTs, providing the rationale for the clinical use of KIT inhibitors regardless of KIT mutation. ..
  14. doi request reprint Superselective intra-arterial chemoradiation therapy for functional laryngeal preservation in advanced squamous cell carcinoma of the glottic larynx
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan
    Acta Otolaryngol 133:633-40. 2013
    ....
  15. doi request reprint Role of TGF-β in tissue eosinophilia associated with vernal keratoconjunctivitis
    Kaori Ohtomo
    Department of Ophthalmology, Juntendo University School of Medicine, 3 1 3 Hongo, Bunkyo ku, Tokyo 113 8431, Japan
    Exp Eye Res 91:748-54. 2010
    ..This effect of TGF-β(1) and IL-4/IL-13 was inhibited by glucocorticoids, but neither by cyclosporine nor by tacrolimus. In conclusion, TGF-β(1) has an important role in the tissue eosinophilia associated with VKC...
  16. doi request reprint Retinal degeneration and rd1 mutation in NC/Tnd mice-a human atopic dermatitis model
    Kaoru Karasawa
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Curr Eye Res 36:350-7. 2011
    ..The purposes of the current study were to investigate the development of retinal degeneration in NC/Tnd mice...
  17. pmc Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy
    Mina Nakatsukasa
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Am J Pathol 177:1344-55. 2010
    ..These results indicate that loss of function of the TACSTD2 gene impairs epithelial barrier function through decreased expression and altered subcellular localization of tight junction-related proteins in GDLD corneas...
  18. doi request reprint Daily intake of Jeju groundwater improves the skin condition of the model mouse for human atopic dermatitis
    Akane Tanaka
    Laboratories of Comparative Animal Medicine, Tokyo, Japan
    J Dermatol 40:193-200. 2013
    ..The early inflammation and hypersensitivity in the atopic skin was alleviated in mice supplied with Jeju groundwater, suggesting its profitable potential on the daily care of patients with skin troubles including AD...
  19. pmc Topical application of ketoprofen improves gait disturbance in rat models of acute inflammation
    Yosuke Amagai
    Cooperative Major in Advanced Health Science, Graduate School of Bio Applications and System Engineering, Tokyo University of Agriculture and Technology, 3 8 5 Saiwai cho, Fuchu, Tokyo, Japan
    Biomed Res Int 2013:540231. 2013
    ..To the best of our knowledge, this is the first report demonstrating the effectiveness of topical NSAIDs in experimental animal models of acute inflammation...
  20. doi request reprint Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease
    Noriko Okamoto
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    Cardiovasc Res 92:209-17. 2011
    ..In this study, we examined the clinical efficacy of silencing the int6 gene, which encodes a protein that stabilizes hypoxia-inducible factor (HIF)-2α, on angiogenesis in PAD...
  21. ncbi request reprint Vernal keratoconjunctivitis with giant papillae on the inferior tarsal conjunctiva
    Yosuke Asada
    Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan and Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Cornea 33:32-4. 2014
    ..We found 3 cases of giant papillae on the inferior tarsal conjunctiva, and diagnosed them as being VKC based on their clinical and histopathological features...
  22. doi request reprint Suppressive effect of mangosteen rind extract on the spontaneous development of atopic dermatitis in NC/Tnd mice
    Hiroaki Higuchi
    Graduate School of Bio Applications and System Engineering, Cooperative Major in Advanced Health Science, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan Central Laboratory, LOTTE Co, Ltd, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    J Dermatol 40:786-96. 2013
    ..Keratinocyte proliferation was well-controlled by ME application. Oral administration of ME exhibited its suppressive potential on the early development of AD by controlling inflammation, itch and epidermal barrier function...
  23. ncbi request reprint Laryngeal preservation in advanced piriform sinus squamous cell carcinomas using superselective intra-arterial chemoradiation therapy with three agents
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan
    Acta Otolaryngol 133:318-26. 2013
    ..Superselective intra-arterial chemotherapy, which enables local control and laryngeal preservation, is a safe and useful therapy for preservation of nutrition, speech, and swallowing functions...
  24. doi request reprint Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing
    Nobuyuki Ebihara
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 52:8549-57. 2011
    ..To investigate the role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing...
  25. doi request reprint Multidrug resistance in mucoepidermoid carcinoma of the parotid gland--immunohistochemical investigations of P-glycoprotein expression
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    Acta Otolaryngol 133:552-7. 2013
    ..The tumor size-related difference in P-glycoprotein expression was only significant for staining with one antibody, and no significant differences were observed with or without induction chemotherapy...
  26. doi request reprint Alarmins from corneal epithelial cells upregulate CCL11 and VCAM-1 in corneal fibroblasts
    Ken Fukuda
    Department of Ophthalmology, Kochi Medical School, Nankoku City, Kochi, Japan
    Invest Ophthalmol Vis Sci 54:5817-23. 2013
    ....
  27. doi request reprint Differences in blast immunophenotypes among disease types in myelodysplastic syndromes: a multicenter validation study
    Kiyoyuki Ogata
    Division of Hematology, Department of Medicine, Nippon Medical School, Tokyo, Japan
    Leuk Res 36:1229-36. 2012
    ..Logistic regression analyses showed that, in addition to myeloblast percentages, the expression of CD7 and B7-H1 on myeloblasts was independently associated with AL-MDS patients...
  28. doi request reprint Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2
    Akane Tanaka
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, 3 5 8 Saiwai cho, Fuchu, Tokyo, Japan
    Am J Physiol Cell Physiol 301:C1360-7. 2011
    ..This is the first study that provides evidence for a novel role of mast cells in adipogenesis via PPARγ activation...
  29. pmc High-affinity IgE receptor-beta chain expression in human mast cells
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Immunol Methods 336:229-34. 2008
    ..Upregulation of beta-chain expression with monomeric IgE treatment suggests possible roles of FcepsilonRI-beta protein as an atopy-related molecule...
  30. ncbi request reprint Investigation of the corneal filament in filamentary keratitis
    Hidetoshi Tanioka
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 50:3696-702. 2009
    ..In this study, an immunohistochemical technique was used to clarify the exact composition of the corneal filament in filamentary keratitis. In addition, the mechanisms responsible for filament formation were identified...
  31. doi request reprint Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II
    Hyunho Lee
    Department of Molecular Cell Immunology and Allergology, Nihon University School of Medicine, Tokyo, Japan
    Arthritis Rheum 65:109-19. 2013
    ..However, IgG receptor expression on human synovial MCs remains uncharacterized. The aim of this study was to identify which IgG receptor(s) on synovial MCs are responsible for MC activation in immune complexes...
  32. doi request reprint Perlecan-deficient mutation impairs corneal epithelial structure
    Takenori Inomata
    Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 53:1277-84. 2012
    ..To elucidate the role of perlecan (Hspg2), a large multidomain heparan sulfate proteoglycan expressed in the basement membrane, in the structure of the corneal epithelium...
  33. ncbi request reprint Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts
    Akira Matsuda
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 48:583-9. 2007
    ..This study was conducted to examine the genetic association between the atopy-related genes and patients with ocular complications (ocular AD)...
  34. doi request reprint Superselective intra-arterial chemotherapy for laryngeal preservation in carcinoma of the anterior oropharyngeal wall
    Tohru Furusaka
    Department of Otolaryngology Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan
    Acta Otolaryngol 133:194-202. 2013
    ..Superselective intra-arterial chemotherapy, which can provide local control and laryngeal preservation, is safe and useful for preserving pharyngeal and laryngeal functions...
  35. pmc LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population
    Kazuhiko Mori
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Mol Vis 14:1037-40. 2008
    ..We also quantified LOXL1 mRNA expression in the human lens capsule to examine the possible correlation between LOXL1 expression and XFG pathogenesis...
  36. doi request reprint Peroxisome proliferator-activated receptor γ-mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice
    Kyungsook Jung
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
    J Allergy Clin Immunol 127:420-429.e1-6. 2011
    ..Because peroxisome proliferator-activated receptor (PPAR) γ acts as a negative regulator in immune cells, suppressive properties of PPARγ in allergic responses have been proposed...
  37. pmc IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis
    Wakako Nakanishi
    Department of Otolaryngology Head and Neck Surgery, The University of Tokyo, Tokyo, Japan
    PLoS ONE 8:e78099. 2013
    ..These observations suggest that IL-33 neutralization may be a potential approach for treatment of HDM-induced AR in humans. ..
  38. doi request reprint Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL: a 36-month analysis of a phase I and II study
    Kensuke Usuki
    Division of Hematology, NTT Kanto Medical Center, 5 9 22 Higashigotanda, Shinagawa ku, Tokyo, Japan
    Int J Hematol 95:409-19. 2012
    ..These results support the favorable long-term efficacy and tolerability of nilotinib in Japanese patients with imatinib-resistant or -intolerant chronic-phase chronic myeloid leukemia...
  39. pmc Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: a prospective validation study
    Kiyoyuki Ogata
    Division of Hematology, Department of Medicine, Nippon Medical School, Tokyo, Japan
    Haematologica 94:1066-74. 2009
    ..The diagnosis of myelodysplastic syndromes is not always straightforward when patients lack specific diagnostic markers, such as blast excess, karyotype abnormality, and ringed sideroblasts...
  40. ncbi request reprint Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium
    Kazuhiko Yoshida
    Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo, Japan
    Invest Ophthalmol Vis Sci 43:364-70. 2002
    ..To examine the expression of the p27(KIP1)in the normal and epithelial-scraped cornea and whether degradation of p27(KIP1)by Skp2 is involved in the regulation of cell proliferation in response to wounding of the corneal epithelium...