Takahisa Hirose

Summary

Affiliation: Juntendo University School of Medicine
Country: Japan

Publications

  1. pmc Glucose monitoring after fruit peeling: pseudohyperglycemia when neglecting hand washing before fingertip blood sampling: wash your hands with tap water before you check blood glucose level
    Takahisa Hirose
    Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Diabetes Care 34:596-7. 2011
  2. pmc Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Diabetes 59:1030-7. 2010
  3. ncbi request reprint Repetitive postprandial hypertriglyceridemia induces monocyte adhesion to aortic endothelial cells in Goto-Kakizaki rats
    Kayoko Motojima
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 55:373-9. 2008
  4. doi request reprint Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension
    Shiho Nakayama
    Department of Medicine, Metabolism, and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Hypertens Res 31:7-13. 2008
  5. ncbi request reprint Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Metabolism 57:1299-306. 2008
  6. ncbi request reprint Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes
    Chie Ohmura
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 56:149-56. 2009
  7. ncbi request reprint Comparison of glycated albumin (GA) and glycated hemoglobin (HbA1c) in type 2 diabetic patients: usefulness of GA for evaluation of short-term changes in glycemic control
    Satomi Takahashi
    Metabolism and Endocrinology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 54:139-44. 2007
  8. ncbi request reprint Long-term efficacy of insulin glargine after switching from NPH insulin as intensive replacement of basal insulin in Japanese diabetes mellitus. Comparison of efficacy between type 1 and type 2 diabetes (JUN-LAN Study 1.2)
    Yoshie Kanazawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 54:975-83. 2007
  9. doi request reprint Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury
    Hiromasa Goto
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Biochem Biophys Res Commun 405:79-84. 2011
  10. doi request reprint Masked hypertension, endothelial dysfunction, and arterial stiffness in type 2 diabetes mellitus: a pilot study
    Kageumi Takeno
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Am J Hypertens 25:165-70. 2012

Collaborators

Detail Information

Publications35

  1. pmc Glucose monitoring after fruit peeling: pseudohyperglycemia when neglecting hand washing before fingertip blood sampling: wash your hands with tap water before you check blood glucose level
    Takahisa Hirose
    Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Diabetes Care 34:596-7. 2011
    ..To examine whether hand contamination with fruit results in a false blood glucose (BG) reading using capillary fingertip blood sample...
  2. pmc Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Diabetes 59:1030-7. 2010
    ..The aim of this study was to investigate the effects of GLP-1 on accumulation of monocytes/macrophages on the vascular wall, one of the earliest steps in atherosclerogenesis...
  3. ncbi request reprint Repetitive postprandial hypertriglyceridemia induces monocyte adhesion to aortic endothelial cells in Goto-Kakizaki rats
    Kayoko Motojima
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 55:373-9. 2008
    ..This increased monocyte adhesion is associated with the increased aortic expression of adhesion molecules such as ICAM-1, and connecting segment-1 fibronectin...
  4. doi request reprint Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension
    Shiho Nakayama
    Department of Medicine, Metabolism, and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Hypertens Res 31:7-13. 2008
    ..Our results indicate that olmesartan has more potent arterial blood pressure lowering and anti-inflammatory effects than telmisartan...
  5. ncbi request reprint Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Metabolism 57:1299-306. 2008
    ..Further studies are needed to elucidate the long-term effects on enhanced GLP-1 secretion and anti-atherosclerosis...
  6. ncbi request reprint Aldose reductase inhibitor, epalrestat, reduces lipid hydroperoxides in type 2 diabetes
    Chie Ohmura
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 56:149-56. 2009
    ..Given the importance of measuring lipid hydroperoxides in erythrocytes as an index of oxidative stress, these results highlight the potential usefulness of epalrestat in reducing oxidative stress in type 2 diabetes mellitus...
  7. ncbi request reprint Comparison of glycated albumin (GA) and glycated hemoglobin (HbA1c) in type 2 diabetic patients: usefulness of GA for evaluation of short-term changes in glycemic control
    Satomi Takahashi
    Metabolism and Endocrinology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 54:139-44. 2007
    ..These results demonstrate that, although unknown influences on GA or HbA1c may exist, GA may be a useful marker for monitoring short-term variations of glycemic control during treatment of diabetic patients...
  8. ncbi request reprint Long-term efficacy of insulin glargine after switching from NPH insulin as intensive replacement of basal insulin in Japanese diabetes mellitus. Comparison of efficacy between type 1 and type 2 diabetes (JUN-LAN Study 1.2)
    Yoshie Kanazawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 54:975-83. 2007
    ....
  9. doi request reprint Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injury
    Hiromasa Goto
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Biochem Biophys Res Commun 405:79-84. 2011
    ..Our results suggested that exendin-4 reduced intimal thickening after vascular injury at least in part by the suppression of platelet-derived growth factor-induced smooth muscle cells proliferation...
  10. doi request reprint Masked hypertension, endothelial dysfunction, and arterial stiffness in type 2 diabetes mellitus: a pilot study
    Kageumi Takeno
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Am J Hypertens 25:165-70. 2012
    ..The aim of this study was to assess the relationship between masked hypertension (MHT) and vascular damage in patients with type 2 diabetes...
  11. pmc Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance
    Naoki Kumashiro
    Department of Medicine, Metabolism, and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Diabetes 57:2083-91. 2008
    ..However, whether and how the reduction of ROS levels improves insulin resistance remains to be elucidated. The present study was designed to define this mechanism...
  12. ncbi request reprint Preferable effect of pravastatin compared to atorvastatin on beta cell function in Japanese early-state type 2 diabetes with hypercholesterolemia
    Tomoya Mita
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 54:441-7. 2007
    ..In conclusion, our study suggests that pravastatin has a favorable effect on pancreatic beta cell function compared with atorvastatin...
  13. ncbi request reprint Long-term effect of combination therapy with mitiglinide and once daily insulin glargine in patients who were successfully switched from intensive insulin therapy in short-term study
    Naoki Kumashiro
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 54:163-6. 2007
    ..0 +/- 1.0%). In conclusion, mitiglinide and insulin glargine combination therapy maintained fair glycemic control for as long as 6 months in subpopulation of Japanese patients with type 2 diabetes...
  14. ncbi request reprint Association of C-reactive protein with early-stage carotid atherosclerosis in Japanese patients with early-state type 2 diabetes mellitus
    Tomoya Mita
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    Endocr J 53:693-8. 2006
    ....
  15. doi request reprint Impact of insulin resistance on enhanced monocyte adhesion to endothelial cells and atherosclerogenesis independent of LDL cholesterol level
    Tomoya Mita
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113 8421, Japan
    Biochem Biophys Res Commun 395:477-83. 2010
    ..Decreased insulin signaling in macrophages associated with systemic insulin resistance could be involved, at least in part, in this pathological process...
  16. doi request reprint Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Biochem Biophys Res Commun 390:809-14. 2009
    ..While GLP-1 enhances proliferation of beta-cells in some diabetic mice models, our results suggest that GLP-1 stimulates beta-cell growth only when expansion of beta-cell mass is required to meet metabolic demands...
  17. ncbi request reprint 2-Methoxyestradiol reduces monocyte adhesion to aortic endothelial cells in ovariectomized rats
    Atsuko Kurokawa
    Department of Gynecology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 54:1027-31. 2007
    ..Our data suggested that 2-ME mediates the anti-atherosclerotic actions of estradiol at least in part by preventing monocyte adhesion to the aortic endothelium...
  18. ncbi request reprint Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure
    Chie Ohmura
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 54:805-11. 2007
    ..Our data confirm the usefulness of lipid hydroperoxides in erythrocyte membrane as a marker of oxidative stress in vivo, and indicate that azelnidipine has a unique antioxidative property in human...
  19. ncbi request reprint Strict glycemic control ameliorates the increase of carotid IMT in patients with type 2 diabetes
    Masahiko Kawasumi
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 53:45-50. 2006
    ..035 +/- 0.019 vs. 0.036 +/- 0.015 mm, M +/- SEM, p<0.001). These results indicate that further improvement of glycemic control from a good HbA1c value can prevent an increase of IMT in type 2 diabetic patients...
  20. ncbi request reprint Acarbose, an alpha-glucosidase inhibitor, improves endothelial dysfunction in Goto-Kakizaki rats exhibiting repetitive blood glucose fluctuation
    Kosuke Azuma
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Biochem Biophys Res Commun 345:688-93. 2006
    ....
  21. ncbi request reprint Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice
    Jiaqing Shao
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Biochem Biophys Res Commun 344:1224-33. 2006
    ..Our results showed that candesartan partially prevented deterioration of glucose tolerance by providing protection against progressive beta-cell damage in diabetes...
  22. doi request reprint Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance
    Yukiko Toyofuku
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, Hongo, Bunkyo ku, Tokyo, Japan
    Biochem Biophys Res Commun 383:303-7. 2009
    ..Thus, normal islet vascularization does not seem to be essential for expansion of beta cell mass in response to insulin resistance...
  23. pmc Combination of the Framingham risk score and carotid intima-media thickness improves the prediction of cardiovascular events in patients with type 2 diabetes
    Michiko Yoshida
    Department of Medicine, Metabolism, and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Diabetes Care 35:178-80. 2012
    ....
  24. ncbi request reprint Rationale and design of the carotid plaque in human for all evaluations with aggressive rosuvastatin therapy (CHALLENGER trial): evaluation by magnetic resonance imaging
    Katsumi Miyauchi
    Department of Cardiovascular Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Circ J 73:111-5. 2009
    ..However, it is not known whether statin therapy achieves similar quantitative improvement in carotid artery plaque in other ethnic groups...
  25. ncbi request reprint Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy
    Hiroko Abe
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 56:911-3. 2009
    ..In both cases, pioglitazone rapidly improved glycemic control, enhanced adiponectin production, and reduced inflammatory cytokines. These results suggest that pioglitazone may be suitable for these patients...
  26. ncbi request reprint Combined expression of transcription factors induces AR42J-B13 cells to differentiate into insulin-producing cells
    Takeshi Ogihara
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 55:691-8. 2008
    ..1 or MafA induces AR42J-B13 cells to differentiate into insulin-producing cells, supporting the use of these cells as a model system for studying beta-cell differentiation in vitro...
  27. doi request reprint Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway
    Koji Komiya
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Biochem Biophys Res Commun 401:561-7. 2010
    ..Considered together, our study suggested that FFA stimulated functional autophagy possibly through the PKR-JNK1 pathway independent of ER or oxidative stress...
  28. doi request reprint IRS-2 deficiency in macrophages promotes their accumulation in the vascular wall
    Tomoya Mita
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113 8421, Japan
    Biochem Biophys Res Commun 415:545-50. 2011
    ..These results suggest a role for insulin resistance in macrophages in early atherosclerogenesis...
  29. ncbi request reprint Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients
    Toyoyoshi Uchida
    Department of Medicine, Juntendo University, Graduate School, Bunkyo ku, Tokyo, Japan
    Endocr J 57:439-43. 2010
    ..The optimal sensitivity and specificity were 83.7% and 92.3%, respectively, using 45 cm/sec as the cutoff value. In conclusion measurement of STA-PSV by ultrasonography is useful for the diagnosis of thyrotoxicosis in Japanese patients...
  30. ncbi request reprint Glucose homeostasis in a diabetic patient during liver transplantation: a case report
    Masayuki Arakawa
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 54:819-23. 2007
    ..We analyzed the levels of blood glucose, insulin and various other hormones during the anhepatic phase. This could be the first report on glucose homeostasis during the anhepatic phase in a diabetic patient...
  31. ncbi request reprint Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects
    Fumihiko Sato
    Department of Medicine, Metabolism, and Endocrinology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 113 8421, Japan
    J Clin Endocrinol Metab 92:3326-9. 2007
    ..Although moderate weight reduction is recommended as primary therapy of metabolic syndrome, little information is known regarding metabolic changes associated with moderate weight reduction in nondiabetic obese subjects...
  32. ncbi request reprint N-(carboxymethyl)valine residues in hemoglobin (CMV-Hb) reflect accumulation of oxidative stress in diabetic patients
    Satoshi Shimada
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Diabetes Res Clin Pract 69:272-8. 2005
    ..The CMV-Hb level was decreased by antioxidant therapy, whereas HbA1c did not change. These results demonstrate that CMV-Hb may be a useful marker for accumulation of oxidative stress in diabetic patients...
  33. doi request reprint Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice
    Motoyuki Tamaki
    Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Bunkyo ku, Tokyo, Japan
    Islets 1:124-8. 2009
    ..As a conclusion, ZnT8 is expressed in multiple lineages of endocrine cells in the pancreas. Our findings suggest that downregulation of ZnT8 may be associated with impaired function of β-cells in diabetes...
  34. ncbi request reprint Therapeutic efficacy of mitiglinide combined with once daily insulin glargine after switching from multiple daily insulin regimen of aspart insulin and glargine in patients with type 2 diabetes mellitus
    Tomoaki Yoshihara
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, School of Medicine, Tokyo, Japan
    Endocr J 53:67-72. 2006
    ..The long-term effects of such treatment need to be established in future studies...
  35. ncbi request reprint Acute onset and worsening of diabetes concurrent with administration of statins
    Chie Ohmura
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Endocr J 52:369-72. 2005
    ..In the general population, statin does not seem to have critical adverse effects on glucose tolerance, but it may uncommonly modify the natural course of the development of diabetes in certain patients...