Hidekatsu Yanai

Summary

Affiliation: Jikei University School of Medicine
Country: Japan

Publications

  1. pmc Myositis, Vasculitis, Hepatic Dysfunction in Adult-Onset Still's Disease
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, The Jikei University School of Medicine, 163 1, Kashiwashita, Kashiwa, Chiba 277 8567, Japan
    Case Report Med 2009:504897. 2009
  2. pmc A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance
    Hidekatsu Yanai
    Department of Internal Medicine, Jikei University School of Medicine, Chiba, Japan
    Diabetes Metab Syndr Obes 3:1-6. 2010
  3. pmc Antihypertensive effects of astaxanthin
    Hidekatsu Yanai
    Department of Internal Medicine
    Integr Blood Press Control 1:1-3. 2008
  4. pmc Diacylglycerol oil for the metabolic syndrome
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Nutr J 6:43. 2007
  5. doi request reprint Effects of diacylglycerol on glucose, lipid metabolism, and plasma serotonin levels in lean Japanese
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Obesity (Silver Spring) 16:47-51. 2008
  6. ncbi request reprint Atherosclerosis imaging in statin intervention trials
    H Yanai
    Department of Internal Medicine, Jikei University School of Medicine, Chiba 277 8567, Japan
    QJM 100:253-62. 2007
  7. pmc Attenuated aerobic exercise capacity in CD36 deficiency
    Hidekatsu Yanai
    Department of Laboratory Medicine, Hokkaido University School of Medicine, Sapporo 060 8648, Japan
    J Med Genet 44:445-7. 2007
  8. ncbi request reprint The possible contribution of a general glycosphingolipid transporter, GM2 activator protein, to atherosclerosis
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, Kashiwa Hospital, The Jikei University School of Medicine, Chiba, Japan
    J Atheroscler Thromb 13:281-5. 2006
  9. ncbi request reprint Severe hypoglycemia in a patient with anorexia nervosa
    H Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba 277 8567, Japan
    Eat Weight Disord 13:e1-3. 2008
  10. pmc The underlying mechanisms for development of hypertension in the metabolic syndrome
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Nutr J 7:10. 2008

Collaborators

Detail Information

Publications38

  1. pmc Myositis, Vasculitis, Hepatic Dysfunction in Adult-Onset Still's Disease
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, The Jikei University School of Medicine, 163 1, Kashiwashita, Kashiwa, Chiba 277 8567, Japan
    Case Report Med 2009:504897. 2009
    ....
  2. pmc A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance
    Hidekatsu Yanai
    Department of Internal Medicine, Jikei University School of Medicine, Chiba, Japan
    Diabetes Metab Syndr Obes 3:1-6. 2010
    ..We studied the molecular mechanisms for DAG-mediated increase in serotonin and EE...
  3. pmc Antihypertensive effects of astaxanthin
    Hidekatsu Yanai
    Department of Internal Medicine
    Integr Blood Press Control 1:1-3. 2008
    ..Astaxanthin has anti-inflammatory, antidiabetic, antihypertensive, and antioxidative activities; therefore, we should perform further studies to elucidate an antiatherogenic effect of astaxanthin...
  4. pmc Diacylglycerol oil for the metabolic syndrome
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Nutr J 6:43. 2007
    ..Further, the therapeutic application of DAG for the metabolic syndrome will be considered...
  5. doi request reprint Effects of diacylglycerol on glucose, lipid metabolism, and plasma serotonin levels in lean Japanese
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Obesity (Silver Spring) 16:47-51. 2008
    ..Further, to reveal the mechanism for increased EE by DAG, we measured plasma serotonin, which is mostly present in the small intestine and mediates peripheral sympathetic thermogenesis...
  6. ncbi request reprint Atherosclerosis imaging in statin intervention trials
    H Yanai
    Department of Internal Medicine, Jikei University School of Medicine, Chiba 277 8567, Japan
    QJM 100:253-62. 2007
  7. pmc Attenuated aerobic exercise capacity in CD36 deficiency
    Hidekatsu Yanai
    Department of Laboratory Medicine, Hokkaido University School of Medicine, Sapporo 060 8648, Japan
    J Med Genet 44:445-7. 2007
    ..FA is a predominant substrate in energy production during light exercise below the anaerobic threshold (AT). We studied whether aerobic exercise capacity in humans could be affected by CD36 deficiency...
  8. ncbi request reprint The possible contribution of a general glycosphingolipid transporter, GM2 activator protein, to atherosclerosis
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, Kashiwa Hospital, The Jikei University School of Medicine, Chiba, Japan
    J Atheroscler Thromb 13:281-5. 2006
    ..Collectively, elevated levels of GM2 activator protein in the aorta may be another feature of human atherosclerosis...
  9. ncbi request reprint Severe hypoglycemia in a patient with anorexia nervosa
    H Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba 277 8567, Japan
    Eat Weight Disord 13:e1-3. 2008
    ..Severe hypoglycemia is an important but uncommon complication of anorexia nervosa. A 35-year-old woman showed severe hypoglycemia after a recovery from severe liver dysfunction due to malnutrition...
  10. pmc The underlying mechanisms for development of hypertension in the metabolic syndrome
    Hidekatsu Yanai
    Department of Internal Medicine, The Jikei University School of Medicine, Chiba, Japan
    Nutr J 7:10. 2008
    ..Here, we will discuss how these factors influence on development of hypertension in the metabolic syndrome...
  11. pmc Clinical, radiological, and biochemical characteristics in patients with diseases mimicking polymyalgia rheumatica
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, The Jikei University School of Medicine, Kashiwa, Japan
    Clin Interv Aging 4:391-5. 2009
    ..Pitting edema of the back of hands and symmetric gallium uptake in MCP joints are characteristic for RS3PE syndrome...
  12. doi request reprint Estimation of lipoprotein profile in patients with type II diabetes and its relevance to remnant lipoprotein cholesterol levels
    Hiroshi Yoshida
    Department of Laboratory Medicine, Jikei University Kashiwa Hospital, 163 1 Kashiwashita Kashiwa, Chiba 277 8567, Japan
    Atherosclerosis 222:541-4. 2012
    ..Remnant lipoprotein (RLP), associated with atherosclerosis progression, is often elevated in diabetes mellitus. The RLP level is estimated by immune-separation method and agarose-gel electrophoresis (AGE)...
  13. ncbi request reprint Effects of supervised aerobic exercise training on serum adiponectin and parameters of lipid and glucose metabolism in subjects with moderate dyslipidemia
    Hiroshi Yoshida
    Department of Laboratory Medicine, Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan
    J Atheroscler Thromb 17:1160-6. 2010
    ..To examine the effects of supervised aerobic exercise training on serum adiponectin and lipids, including triglyceride (TG)-rich lipoproteins, in moderate dyslipidemic subjects...
  14. ncbi request reprint [Therapeutic application of diacylglycerol oil for the metabolic syndrome]
    Hidekatsu Yanai
    Department of Internal Medicine, International Medical Center of Japan Kohnodai Hospital, Ichikawa, Chiba 272 8516, Japan
    Rinsho Byori 58:39-44. 2010
    ..Our studies presented DAG-mediated amelioration in postprandial TG-rich lipoprotein, insulin, and energy metabolism, indicating the therapeutic application of DAG for the metabolic syndrome...
  15. pmc Characteristic comparison of triglyceride-rich remnant lipoprotein measurement between a new homogenous assay (RemL-C) and a conventional immunoseparation method (RLP-C)
    Hiroshi Yoshida
    Department of Laboratory Medicine, Jikei University Kashiwa Hospital, Japan
    Lipids Health Dis 7:18. 2008
    ....
  16. doi request reprint Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia
    Hiroshi Yoshida
    Department of Laboratory Medicine, Jikei University Kashiwa Hospital, Chiba, Japan Department of General Medicine, Jikei University Kashiwa Hospital, Chiba, Japan
    Atherosclerosis 226:161-4. 2013
    ..The effects of potent statins on oxidized lipoprotein biomarkers are not well defined...
  17. doi request reprint Relevance of intermediate-density lipoprotein cholesterol to Framingham risk score of coronary heart disease in middle-aged men with increased non-HDL cholesterol
    Kumie Ito
    Department of Internal Medicine, Jikei University Kashiwa Hospital, Chiba, Japan Tobu Medical Center, Shizuoka, Japan Institute of Clinical Medicine and Research, Jikei University School of Medicine, Chiba, Japan
    Int J Cardiol 168:3853-8. 2013
    ..The present study investigated the relevance of TG-rich lipoproteins (IDL, VLDL, CM) to Framingham risk score (FRS) predictive of 10-year CHD risk...
  18. doi request reprint Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia
    Hiroshi Yoshida
    Department of Laboratory Medicine, Jikei University Kashiwa Hospital, Chiba, Japan
    Atherosclerosis 209:520-3. 2010
    ..Astaxanthin has been reported to improve dyslipidemia and metabolic syndrome in animals, but such effects in humans are not well known...
  19. ncbi request reprint Comparative study between anion-exchange HPLC and homogeneous assay methods in regard to the accuracy of high- and low-density lipoprotein cholesterol measurement
    Hideo Kurosawa
    Department of Laboratory Medicine, Jikei University Hospital, Japan
    Clin Biochem 40:1291-6. 2007
    ..The present study was performed to compare this HPLC method to homogenous assay in regard to measurement accuracy of HDL and LDL cholesterol...
  20. ncbi request reprint [Environmental factors associated with the onset of lipid metabolism disorders]
    Hidekatsu Yanai
    Division of General Medicine, Department of Internal Medicine, The Jikei University School of Medicine, Kashiwa Hospital
    Nihon Rinsho 65:136-40. 2007
  21. ncbi request reprint Unique character and metabolism of high density lipoprotein (HDL) in fetus
    Hironori Nagasaka
    Department of Pediatrics, Hokkaido University School of Medicine, N15 W7, Sapporo 060 8638, Japan
    Atherosclerosis 161:215-23. 2002
    ..These results indicate that, in fetus, the character and metabolism of HDL, especially of apo E-rich HDL cholesterol, are distinct from those in adults...
  22. ncbi request reprint Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury
    Hiroshi Yoshida
    Department of Internal Medicine, Division of General Medicine, Kashiwa Hospital, Jikei University School of Medicine, Kashiwa, Chiba, Japan
    CNS Drug Rev 12:9-20. 2006
    ..The combination therapy (a thrombolytic plus edaravone) is likely to target brain edema, reduce stroke death and improve the recovery from neurological deficits in stoke patients...
  23. pmc Correlations of non-exercise activity thermogenesis to metabolic parameters in Japanese patients with type 2 diabetes
    Hidetaka Hamasaki
    Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan
    Diabetol Metab Syndr 5:26. 2013
    ..Non-exercise activity thermogenesis (NEAT) is the energy expenditure due to physical activities besides active sports-like exercise and resistance training in daily life...
  24. pmc Hyperinsulinemia and insulin resistance in a patient with type 2 diabetes complicated with myelofibrosis
    Hidetaka Hamasaki
    Hidetaka Hamasaki, Shuichi Mishima, Hidekatsu Yanai, Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba 272 8516, Japan
    World J Diabetes 3:156-7. 2012
    ..However, an association between myelofibrosis and insulin resistance has not ever been discussed anywhere. Here we report a case of type 2 diabetes showing remarkable hyperinsulinemia and insulin resistance possibly due to myelofibrosis...
  25. pmc A teenager with abdominal pain and soft-tissue emphysema
    Hidekatsu Yanai
    Department of Emergency Medicine, Jikei University School of Medicine, Kashiwa, Japan
    CMAJ 174:624. 2006
  26. ncbi request reprint Prevalence and in-hospital mortality of gastrostomy and jejunostomy in Japan: a retrospective study with a national administrative database
    Akahito Sako
    Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, Japan
    Gastrointest Endosc 80:88-96. 2014
    ..PEG is widely used; however, large-scale data for PEG have been lacking...
  27. pmc A patient with Graves' disease showing only psychiatric symptoms and negativity for both TSH receptor autoantibody and thyroid stimulating antibody
    Hidetaka Hamasaki
    Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan
    Thyroid Res 5:19. 2012
    ..abstract:..
  28. pmc Effects of 6-month sitagliptin treatment on glucose and lipid metabolism, blood pressure, body weight and renal function in type 2 diabetic patients: a chart-based analysis
    Hidekatsu Yanai
    Department of Internal Medicine, National Center for Global Health and Medicine, Kohnodai Hospital, Chiba 272 8516, Japan
    J Clin Med Res 4:251-8. 2012
    ..We retrospectively studied effects of 6-month-treatment with sitagliptin on glucose and lipid metabolism, blood pressure, body weight and renal function in patients with type 2 diabetes by a chart-based analysis...
  29. pmc The Underlying Mechanisms for Olanzapine-induced Hypertriglyceridemia
    Hiroki Adachi
    Department of Internal Medicine, National Center for Global Health and Medicine, Kohnodai Hospital, Chiba 272 8516, Japan
    J Clin Med Res 4:206-8. 2012
    ..The cessation of olanzapine significantly decreased high-sensitivity C-reactive protein and increased adiponectin, proposing that inflammation and reduced adiponectin level may be associated with olanzapin-induced hypertriglyceridemia...
  30. ncbi request reprint Effect of ascorbate on serum lipids and urate metabolism during exhaustive training
    Hidekatsu Yanai
    Department of Internal Medicine, Sapporo Self Defense Hospital, Sapporo 062 8610, Japan
    Clin Sci (Lond) 106:107-9. 2004
    ..In conclusion, our results suggested that ascorbate may contribute to the desirable changes in serum lipids during exhaustive training and suggest the significant association between ascorbate and urate under intense training...
  31. ncbi request reprint Metabolic changes in human CD36 deficiency displayed by glucose loading
    H Yanai
    Department of Laboratory Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Thromb Haemost 86:995-9. 2001
    ..Impaired fast FA clearance by muscle and consequently increased hepatic FA uptake seem to underlie these changes. We conclude that human CD36 deficiency causes systemic metabolic changes...
  32. doi request reprint Elevated plasma plasminogen activator inhibitor-1 in CD36 deficiency
    Hidekatsu Yanai
    Diabetes Care 31:e72. 2008
  33. ncbi request reprint Expression of cholesterol sulfotransferase (SULT2B1b) in human skin and primary cultures of human epidermal keratinocytes
    Yuko Higashi
    Section on Steroid Regulation, Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
    J Invest Dermatol 122:1207-13. 2004
    ..Additionally, 88% of cholesterol sulfate in NHEK was membrane-associated further suggesting a cellular location for cholesterol sulfate action...
  34. ncbi request reprint Oxidized low density lipoprotein elevates platelet serotonin release
    Hidekatsu Yanai
    Am J Hematol 82:686-7. 2007
  35. ncbi request reprint Expression of cholesterol sulfotransferase (SULT2B1b) in human platelets
    Hidekatsu Yanai
    Section on Steroid Regulation, Endocrinology, and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 4510, USA
    Circulation 109:92-6. 2004
    ..Among its many demonstrated regulatory actions is its ability to influence blood clotting and fibrinolysis. Additionally, cholesterol sulfate is a constituent of human platelets, where it has been shown to support platelet aggregation...
  36. ncbi request reprint [Hypertriglyceridemia]
    Hiroshi Yoshida
    Department of Laboratory Medicine, The Jikei University School of Medicine Kashiwa Hospital
    Nihon Rinsho 64:378-84. 2006
  37. ncbi request reprint Evaluation of risk for atherosclerosis in Alagille syndrome and progressive familial intrahepatic cholestasis: two congenital cholestatic diseases with different lipoprotein metabolisms
    Hironori Nagasaka
    Division of Metabolism, Chiba Children s Hospital, Japan
    J Pediatr 146:329-35. 2005
    ..To evaluate the risk for atherosclerosis in Alagille syndrome (AGS) and progressive familial intrahepatic cholestasis (PFIC) on the basis of lipoprotein metabolism and by ultrasonography...