Naoko Tajima

Summary

Affiliation: Jikei University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy
    Masaya Sakamoto
    Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Circ Res 99:1411-8. 2006
  2. pmc LDL-cholesterol and body mass index among Japanese schoolchildren: a population-based cross-sectional study
    Takako Shirasawa
    Department of Public Health, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8555, Japan
    Lipids Health Dis 12:77. 2013
  3. ncbi request reprint Epidemiology of childhood diabetes mellitus in Japan
    Naoko Tajima
    The Jikei University School of Medicine, Tokyo, Japan
    Pediatr Endocrinol Rev 10:44-50. 2012
  4. doi request reprint Pravastatin reduces the risk for cardiovascular disease in Japanese hypercholesterolemic patients with impaired fasting glucose or diabetes: diabetes subanalysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (
    Naoko Tajima
    Department of Internal Medicine, Jikei University School of Medicine 3 25 8, Nishi Shimbashi, Minato ku, 105 8461 Tokyo, Japan
    Atherosclerosis 199:455-62. 2008
  5. pmc Prospective randomized study for optimal insulin therapy in type 2 diabetic patients with secondary failure
    Yumi Miyashita
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 7:16. 2008
  6. ncbi request reprint Childhood obesity and its relation to serum adiponectin and leptin: a report from a population-based study
    Rimei Nishimura
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Res Clin Pract 76:245-50. 2007
  7. doi request reprint Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study)
    Kyoichi Mizuno
    Department of Internal Medicine, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Circulation 117:494-502. 2008
  8. ncbi request reprint Suppression of body weight gain preserves acute insulin response to glucose in the portal vein of spontaneously type 2 diabetic rats with visceral obesity
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Japan
    Endocrine 26:139-46. 2005
  9. ncbi request reprint The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats
    Atsushi Gojo
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishi Shimbashi Minato ku, Tokyo, 105 8461, Japan
    Eur J Pharmacol 568:242-7. 2007
  10. pmc Continuous glucose monitoring with Humalog Mix 25 versus Humalog Mix 50, twice daily: a comparative pilot study -results from the Jikei-EValuation of insulin Lispro mixture on pharmacodynamics and glycemic VariancE (J-EVOLVE) study
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 9:16. 2010

Detail Information

Publications105 found, 100 shown here

  1. ncbi request reprint Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy
    Masaya Sakamoto
    Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Circ Res 99:1411-8. 2006
    ..These results suggest that HSF1 plays a critical role in the transition between adaptive and maladaptive hypertrophy...
  2. pmc LDL-cholesterol and body mass index among Japanese schoolchildren: a population-based cross-sectional study
    Takako Shirasawa
    Department of Public Health, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8555, Japan
    Lipids Health Dis 12:77. 2013
    ..The aim of the present study was to investigate the relationship between LDL-C and body mass index (BMI) in population-based Japanese schoolchildren...
  3. ncbi request reprint Epidemiology of childhood diabetes mellitus in Japan
    Naoko Tajima
    The Jikei University School of Medicine, Tokyo, Japan
    Pediatr Endocrinol Rev 10:44-50. 2012
    ..The establishment of an ongoing population-based national T1DM and T2DM registry system is critical for identifying risk factors associated with diabetes and its complications...
  4. doi request reprint Pravastatin reduces the risk for cardiovascular disease in Japanese hypercholesterolemic patients with impaired fasting glucose or diabetes: diabetes subanalysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (
    Naoko Tajima
    Department of Internal Medicine, Jikei University School of Medicine 3 25 8, Nishi Shimbashi, Minato ku, 105 8461 Tokyo, Japan
    Atherosclerosis 199:455-62. 2008
    ..In conclusion, pravastatin reduces the risk of CVD in subjects with hypercholesterolemia and abnormal fasting glucose in the primary prevention setting in Japan...
  5. pmc Prospective randomized study for optimal insulin therapy in type 2 diabetic patients with secondary failure
    Yumi Miyashita
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 7:16. 2008
    ..Therefore it may achieve the blood glucose control as same as that of BB therapy and prevent the diabetic complications including macroangiopathy...
  6. ncbi request reprint Childhood obesity and its relation to serum adiponectin and leptin: a report from a population-based study
    Rimei Nishimura
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Res Clin Pract 76:245-50. 2007
    ..A large-scale, population-based study revealed that AD was lower and LP higher in obese children, and that the obese status in G2 was related to a worse metabolic profile than the case in G1...
  7. doi request reprint Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study)
    Kyoichi Mizuno
    Department of Internal Medicine, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Circulation 117:494-502. 2008
    ..We conducted an exploratory analysis of the effect of diet plus pravastatin therapy on the primary prevention of cardiovascular events in women with data from a large-scale primary prevention trial with pravastatin...
  8. ncbi request reprint Suppression of body weight gain preserves acute insulin response to glucose in the portal vein of spontaneously type 2 diabetic rats with visceral obesity
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Japan
    Endocrine 26:139-46. 2005
    ..Acute insulin response to glucose decreased with advancing age and the suppression of body weight gain preserved the response in spontaneously type 2 diabetic rats with visceral fat obesity...
  9. ncbi request reprint The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats
    Atsushi Gojo
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishi Shimbashi Minato ku, Tokyo, 105 8461, Japan
    Eur J Pharmacol 568:242-7. 2007
    ..We conclude that suppression of the Rho/Rho-kinase pathway could be a new strategy for the treatment of diabetic nephropathy...
  10. pmc Continuous glucose monitoring with Humalog Mix 25 versus Humalog Mix 50, twice daily: a comparative pilot study -results from the Jikei-EValuation of insulin Lispro mixture on pharmacodynamics and glycemic VariancE (J-EVOLVE) study
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 9:16. 2010
    ..To evaluate glycemic variability associated with two different premixed insulin analogue formulations when used in a twice-daily regimen...
  11. pmc Secular trends in blood pressure among Japanese schoolchildren: a population-based annual survey from 1994 to 2010
    Takako Shirasawa
    Department of Public Health, Showa University School of Medicine, Tokyo, Japan
    J Epidemiol 22:448-53. 2012
    ..We investigated secular trends in BP using data from population-based annual screenings of Japanese schoolchildren...
  12. ncbi request reprint Role of hypoadiponectinemia in the metabolic syndrome and its association with post-glucose challenge hyper-free fatty acidemia: a study in prediabetic Japanese males
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 29:357-61. 2006
    ....
  13. ncbi request reprint Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina
    Tamotsu Yokota
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 51:424-30. 2007
    ..To examine the role played by the Rho/Rho kinase pathway in the platelet-derived growth factor BB (PDGF-BB)-induced expression of vascular endothelial growth factor (VEGF) in the diabetic rat retina...
  14. doi request reprint Daily glucose profiles in Japanese people with normal glucose tolerance as assessed by continuous glucose monitoring
    Daisuke Tsujino
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
    Diabetes Technol Ther 11:457-60. 2009
    ..Little information is available regarding glucose fluctuations in postprandial states and during the oral glucose tolerance test (OGTT) in Japanese people with normal glucose tolerance (NGT)...
  15. ncbi request reprint The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia
    Toshitsugu Ishikawa
    Occupational Health Department, Sony Corporation, Tokyo, Japan
    Circ J 72:1576-82. 2008
    ..The present analysis determined the risk factors for CHD in the MEGA Study, a large primary prevention trial with pravastatin in Japanese with hypercholesterolemia...
  16. ncbi request reprint Low prevalence of metabolic syndrome and its components in rural Japan
    Aya Morimoto
    Department of Internal Medicine, Division of Diabetes, Metabolism and Endocrinology, Jikei University School of Medicine, Tokyo, Japan
    Tohoku J Exp Med 216:69-75. 2008
    ..The lower prevalence of MetS and its components in Tsunan may be due to the consumption of traditional Japanese food, which is still commonly eaten there, and the higher levels of regular physical activity of farmers...
  17. ncbi request reprint Association of urinary albumin excretion with insulin resistance in Japanese subjects: impact of gender difference on insulin resistance
    Kazunori Utsunomiya
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Intern Med 48:1621-7. 2009
    ..To investigate the relationship between homeostasis model assessment for insulin resistance (HOMA-R) and urinary albumin excretion in Japanese and clarify gender difference in albuminuria-related insulin resistance...
  18. ncbi request reprint Sleep duration and overweight among elementary schoolchildren: a population-based study in Japan
    Hirotaka Ochiai
    Department of Public Health, Showa University School of Medicine, Shinagawa ku, Tokyo, Japan
    Acta Med Okayama 66:93-9. 2012
    ..These findings suggested that it is important to consider sleep duration as part of any program to prevent overweight among elementary schoolchildren, especially among boys...
  19. ncbi request reprint Angiotensin II receptor blockers downsize adipocytes in spontaneously type 2 diabetic rats with visceral fat obesity
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi gun, Tochigi, Japan
    Am J Hypertens 20:431-6. 2007
    ....
  20. ncbi request reprint Effects of pioglitazone vs glibenclamide on postprandial increases in glucose and triglyceride levels and on oxidative stress in Japanese patients with type 2 diabetes
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 29:143-8. 2006
    ..Our study results suggest that PG suppresses increases in postprandial glucose and TG levels, and improves insulin resistance; and, in addition, that PG may have a favorable impact on oxidative stress in type 2 diabetic patients...
  21. ncbi request reprint Effects of nateglinide on the elevation of postprandial remnant-like particle triglyceride levels in Japanese patients with type 2 diabetes assessment by meal tolerance test
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 25:203-6. 2004
    ..These results suggest that, in a clinical setting, the early insulin response is closely associated with both postprandial glucose and postprandial lipid metabolism in Japanese patients with type 2 diabetes...
  22. ncbi request reprint Gender differences in the relationship between percent body fat (%BF) and body mass index (BMI) in Japanese children
    Aya Morimoto
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8 Nishishinbashi, Tokyo, Japan
    Diabetes Res Clin Pract 78:123-5. 2007
    ..Further study will be necessary to ascertain whether the strong correlation seen among girls will be observed in different age or ethnic groups, and to ascertain the mechanism that produces this gender difference...
  23. pmc Relationship of body mass index to percent body fat and waist circumference among schoolchildren in Japan--the influence of gender and obesity: a population-based cross-sectional study
    Hirotaka Ochiai
    Department of Public Health, Showa University School of Medicine, Tokyo, Japan
    BMC Public Health 10:493. 2010
    ..The aim of the present study was to investigate the relationship of BMI to %BF and WC and to examine the influence of gender and obesity on these relationships among Japanese schoolchildren...
  24. doi request reprint Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system
    Keiichi Ikeda
    Department of Pharmacology, Jikei University School of Medicine, Tokyo, Japan
    Hypertens Res 31:693-706. 2008
    ....
  25. pmc Changes in body mass index, leptin and adiponectin in Japanese children during a three-year follow-up period: a population-based cohort study
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 8:30. 2009
    ..The study examined changes in and relationship between body mass index (BMI), leptin and adiponectin levels over a 3-year period in a pediatric population-based cohort...
  26. ncbi request reprint Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study
    Seibu Mochizuki
    Division of Cardiology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Lancet 369:1431-9. 2007
    ..We aimed to investigate whether addition of an angiotensin receptor blocker, valsartan, to conventional cardiovascular treatment was effective in Japanese patients with cardiovascular disease...
  27. pmc High-molecular-weight adiponectin and anthropometric variables among elementary schoolchildren: a population-based cross-sectional study in Japan
    Hirotaka Ochiai
    Department of Public Health, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku 142 8555, Tokyo, Japan
    BMC Pediatr 12:139. 2012
    ....
  28. ncbi request reprint Japanese IGT subjects with high insulin response are far more frequently associated with the metabolic syndrome than those with low insulin response
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 29:351-5. 2006
    ..It is also shown in middle-aged Japanese males that of the two forms of IGT, IGT with high insulin response is more closely linked to the pathogenesis of atherosclerotic cardiovascular disease...
  29. pmc Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography
    Masami Nemoto
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Cardiovasc Diabetol 6:23. 2007
    ..This study evaluated the effect of genetic polymorphism of enzymes producing or responsible for reducing ROS on coronary artery calcification in type 2 diabetes (T2D)...
  30. ncbi request reprint Short-term effect of bezafibrate on the expression of adiponectin mRNA in the adipose tissues: a study in spontaneously type 2 diabetic rats with visceral obesity
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Japan
    Endocrine 25:247-51. 2004
    ..Findings from this study suggest that in type 2 diabetes with insulin resistance, hypertriglyceridemia is closely linked to adiponectin...
  31. ncbi request reprint In vitro and pathological investigations of MODY5 with the R276X-HNF1beta (TCF2) mutation
    Kei Fujimoto
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Endocr J 54:757-64. 2007
    ..Analysis with light and electron microscopy on biopsied kidney specimens suggested that the origin of the cysts might be glomeruli but the primary lesion could be tubules...
  32. ncbi request reprint Telmisartan improves lipid metabolism and adiponectin production but does not affect glycemic control in hypertensive patients with type 2 diabetes
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Adv Ther 24:146-53. 2007
    ....
  33. ncbi request reprint Glycated albumin is low in obese, type 2 diabetic patients
    Yumi Miyashita
    Division of Diabetes Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Res Clin Pract 78:51-5. 2007
    ..In conclusion, the current analysis demonstrated a need of careful evaluation of GA values in obese diabetic patients in daily practice. Further researches are required to elucidate the underlying mechanisms...
  34. ncbi request reprint Association of polymorphism of estrogen receptor-alpha gene with circulating levels of adiponectin in postmenopausal women with type 2 diabetes
    Rie Yoshihara
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo 105 8461, Japan
    J Atheroscler Thromb 16:250-5. 2009
    ..454-397T>C) might influence circulating levels of adipokines and inflammatory cytokines in postmenopausal women with type 2 diabetes...
  35. doi request reprint Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance
    Ryuzo Kawamori
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Lancet 373:1607-14. 2009
    ..We therefore assessed whether voglibose, an alpha-glucosidase inhibitor, could prevent the development of type 2 diabetes in high-risk Japanese individuals with impaired glucose tolerance...
  36. doi request reprint Comparing the efficacy of α-glucosidase inhibitors in suppressing postprandial hyperglycemia using continuous glucose monitoring: a pilot study-the MAJOR study
    Daisuke Tsujino
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Technol Ther 13:303-8. 2011
    ..This study aimed to compare glucose variability in patients given the α-glucosidase inhibitors miglitol and acarbose using continuous glucose monitoring (CGM)...
  37. ncbi request reprint Coefficient of variation of R-R intervals in electrocardiogram is a sensitive marker of anemia induced by autonomic neuropathy in type 1 diabetes
    Takatoshi Saito
    Department of Medicine, Division of Diabetes and Endocrinology, The Jikei University School of Medicine, 3 25 8 Nishishimbashi, Tokyo, Japan
    Diabetes Res Clin Pract 78:60-4. 2007
    ..We conclude that CVR-R has the strong relationship on anemia without overt nephropathy in type 1 diabetes, indicating that autonomic failure contributes on the progression of anemia via a poor response of EPO to anemia...
  38. doi request reprint Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R
    Tsuyoshi Isaka
    Department of Internal Medicine, Division of Diabetes and Endocrinology, Jikei University School of Medicine, Tokyo, Japan
    Eur J Pharmacol 605:49-52. 2009
    ..On the basis of these findings, azelnidipine appears to suppress steroid biosynthesis in H295R cells beyond the blockade of L-type calcium channels...
  39. pmc Relationship between hemoglobin A1c and cardiovascular disease in mild-to-moderate hypercholesterolemic Japanese individuals: subanalysis of a large-scale randomized controlled trial
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo 105 8461, Japan
    Cardiovasc Diabetol 10:58. 2011
    ..We analyzed this relation using clinical data on Japanese individuals with hypercholesterolemia...
  40. ncbi request reprint Waist circumference estimation from BMI in Japanese children
    Aya Morimoto
    Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8 Nishishimbashi, Tokyo 105 8461, Japan
    Diabetes Res Clin Pract 75:96-8. 2007
    ..This estimation could be an alternative way and useful in detecting childhood metabolic syndrome or obesity disease in which a waist circumference figure is necessary...
  41. doi request reprint Relationship among A1C, hypoglycemia, and hyperglycemia in Japanese with type 2 diabetes--results from continuous glucose monitoring data
    Aya Morimoto
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Technol Ther 13:667-70. 2011
    ....
  42. ncbi request reprint Dietary diacylglycerol reduces postprandial hyperlipidemia and ameliorates glucose intolerance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsumomiya National Hospital, Tochigi, Japan
    Nutrition 21:933-9. 2005
    ..The aim of the present study was to determine the effects of dietary diacylglycerol (DG) on the metabolism of lipids and glucose in type II diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats...
  43. doi request reprint A crossover comparison of glycemic variations in Japanese patients with type 1 diabetes receiving insulin glargine versus insulin detemir twice daily using continuous glucose monitoring (CGM): J COLLECTION (Jikei COmparison of Lantus and LEvemir with Cgm
    Daisuke Tsujino
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Technol Ther 14:596-601. 2012
    ..This study aimed to compare glycemic variations seen among Japanese patients with type 1 diabetes treated with insulin glargine versus insulin detemir using continuous glucose monitoring (CGM) in a crossover design...
  44. doi request reprint Analysis of 24-hour glycemic excursions in patients with type 1 diabetes by using continuous glucose monitoring
    Kentaro Taki
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Technol Ther 12:523-8. 2010
    ..Little information is available regarding postprandial glycemic excursions and hypoglycemia in Japanese patients with type 1 diabetes (T1D)...
  45. ncbi request reprint Ratio of high-, medium-, and low-molecular weight serum adiponectin to the total adiponectin value in children
    Rimei Nishimura
    Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    J Pediatr 151:545-7, 547.e1-2. 2007
    ..A lower total adiponectin value was associated with a lower ratio of HMW adiponectin...
  46. doi request reprint The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cells
    Yasushi Kanazawa
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Japan
    Exp Neurol 247:438-46. 2013
    ..Fasudil, through its effect on the distribution of the adhesion-related molecules, might prevent slowing of the MNCV. ..
  47. doi request reprint Raised fasting plasma glucose a better predictor of diabetes than the IDF definition of the metabolic syndrome
    Tomoko Nakagami
    Diabetes Centre, Tokyo Women s Medical University, Tokyo, Japan
    Diabetes Res Clin Pract 85:e19-21. 2009
    ..Raised FPG was better at identifying future diabetes than either IDF MetS or a constellation of risk factors except for raised FPG with and without abdominal adiposity. This should shed light on a screening program for future DM in Japan...
  48. ncbi request reprint High blood pressure in obese and nonobese Japanese children: blood pressure measurement is necessary even in nonobese Japanese children
    Takako Shirasawa
    Department of Public Health, Showa University School of Medicine, Shinagawa ku, Tokyo, Japan
    J Epidemiol 20:408-12. 2010
    ..We evaluated the prevalences of HT and high-normal blood pressure (HNBP), and examined the relationship between blood pressure (BP) and body mass index (BMI), in Japanese children...
  49. doi request reprint Regulation of urocortin I and its related peptide urocortin II by inflammatory and oxidative stresses in HL-1 cardiomyocytes
    Keiichi Ikeda
    Department of Pharmacology, The Jikei University School of Medicine, Tokyo, Japan
    J Mol Endocrinol 42:479-89. 2009
    ..In conclusion, the Ucn-CRH receptor system may be regulated by two major forms of cardiac stresses, i.e. oxidative and inflammatory stress, and may play a critical role in cardiac stress adaptation in heart diseases...
  50. ncbi request reprint Clinical characteristics of nateglinide response as assessed by insulinogenic indices: preliminary study to determine an optimal indication for nateglinide
    Yutaka Mori
    Department of Internal Medicine, National Higashi Utsunomiya Hospital, Tochigi, Japan
    Adv Ther 20:352-9. 2003
    ....
  51. ncbi request reprint Differential effect of PPARgamma2 variants in the development of type 2 diabetes between native Japanese and Japanese Americans
    Masami Nemoto
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishishinbashi, Minato ku, Tokyo 105 8461, Japan
    Diabetes Res Clin Pract 57:131-7. 2002
    ..The data with emigrants suggests the possible interaction of gene-environment in the development of type 2 diabetes...
  52. ncbi request reprint Differences in the pathology of the metabolic syndrome with or without visceral fat accumulation: a study in pre-diabetic Japanese middle-aged men
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 29:149-53. 2006
    ....
  53. ncbi request reprint Association between postprandial remnant-like particle triglyceride (RLP-TG) levels and carotid intima-media thickness (IMT) in Japanese patients with type 2 diabetes: assessment by meal tolerance tests (MTT)
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 28:157-63. 2005
    ....
  54. doi request reprint Importance of high-density lipoprotein cholesterol control during pravastatin treatment in hypercholesterolemic Japanese with type 2 diabetes mellitus: a post hoc analysis of MEGA study
    Rimei Nishimura
    Jikei University School of Medicine, Tokyo, Japan
    Diabetes Res Clin Pract 100:e31-3. 2013
    ..A significant risk reduction in CVD was found only in diabetic patients who had both a reduction in LDL-C and an increase in HDL-C...
  55. pmc Number of siblings, birth order, and childhood overweight: a population-based cross-sectional study in Japan
    Hirotaka Ochiai
    Department of Public Health, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, 142 8555, Tokyo, Japan
    BMC Public Health 12:766. 2012
    ....
  56. ncbi request reprint Prevalence of metabolic syndrome and optimal waist circumference cut-off values in Japan
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishishinbashi, Tokyo, Japan
    Diabetes Res Clin Pract 78:77-84. 2007
    ..Based on the new values, the prevalence of MetS was found to be 22.8% for males and 19.2% for females. The present study revealed that optimal waist circumference cut-off value was much shorter than that previously proposed in females...
  57. ncbi request reprint Enhanced insulin secretion from engineered 3T3-L1 preadipocytes by induction of cellular differentiation
    Kei Fujimoto
    Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Mol Cell Biochem 268:1-8. 2005
    ..Results of our present study will provide important information on cell-based therapy using undifferentiated progenitors and tissue stem cells...
  58. doi request reprint Possible involvement of corticotropin-releasing factor receptor signaling on vascular inflammation
    Yuri Inada
    Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8, Nishishinbashi, Minato ku, Tokyo, 105 8461, Japan
    Peptides 30:365-72. 2009
    ..In addition, because of up-regulation of CRF-R1 mRNA by pitavastatin with or without TNF-alpha, CRF-R1 may be involved in the vasoprotective effects of pitavastatin...
  59. ncbi request reprint Clinical efficacy of magnesium supplementation in patients with type 2 diabetes
    Kuninobu Yokota
    Department of Internal Medicine, Jikei University School of Medicine, 3 15 8 Nishi shinbashi, Minato ku 105 0003, Japan
    J Am Coll Nutr 23:506S-509S. 2004
    ..01), diastolic (p = 0.0038), and mean (p < 0.01) blood pressure. The salt lake water supplement, MAG21, exerted clinical benefit as a Mg supplement in patients with mild type 2 diabetes mellitus...
  60. ncbi request reprint Is pubertal onset a risk factor for blindness and renal replacement therapy in childhood-onset type 1 diabetes in Japan?
    Aya Morimoto
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 3 25 8 Nishishinbashi, Minato ku, Tokyo, 105 8461, Japan
    Diabetes Care 30:2338-40. 2007
  61. doi request reprint Efficacy of combined use of miglitol in Type 2 diabetes patients receiving insulin therapy-placebo-controlled double-blind comparative study
    Masami Nemoto
    Department of General Internal Medicine, Jikei University School of Medicine Aoto Hospital, Aoto 6 41 2, Katsushika ku, Tokyo, Japan
    Acta Diabetol 48:15-20. 2011
    ..The frequency of nocturnal hypoglycemia events tended to be reduced in Group M. Combined use of insulin and miglitol is useful for postprandial glucose regulation and improves glycemic control...
  62. ncbi request reprint A case of prolactin deficiency with familial puerperal alactogenesis accompanying impaired ACTH secretion
    Takatoshi Saito
    Department of Medicine, Division of Diabetes and Endocrinology, The Jikei University School of Medicine, Tokyo, Japan
    Endocr J 54:59-62. 2007
    ..This evidence suggests that familial puerperal alactogenesis and PRL deficiency can be induced by other causes such as via disorders of unknown transcription factors or molecules that contribute to translation of PRL gene...
  63. ncbi request reprint Coexistence of aldosterone-producing adrenocortical adenoma and pheochromocytoma in an ipsilateral adrenal gland
    Noriko Sakamoto
    Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
    Endocr J 56:213-9. 2009
    ..Risk of operation against undiagnosed PC is very high and, therefore, it must be diagnosed before surgery. Herein, we present an extremely rare case of the simultaneous occurrence of both APA and PC in an ipsilateral adrenal gland...
  64. ncbi request reprint Glycated albumin is low in obese, non-diabetic children
    Rimei Nishimura
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8 Nishishimbashi, Minato ku, Tokyo 105 8461, Japan
    Diabetes Res Clin Pract 71:334-8. 2006
    ..This is the first report to reveal that GA levels are low in obese, non-diabetic children. Additional data collection and an experimental approach are necessary to reveal the reasons behind lower GA levels in obese children...
  65. ncbi request reprint Bezafibrate-induced changes over time in the expression of uncoupling protein (UCP) mRNA in the tissues: a study in spontaneously type 2 diabetic rats with visceral obesity
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, 2160 Shimookamoto, Kawachi machi, Kawachi gun, Tochigi 329 1193, Japan
    J Atheroscler Thromb 11:224-31. 2004
    ..We thus conclude that the PPAR-alpha-mediated effects of BF on the expression of liver UCP2 may be one of the factors that helped to decrease insulin levels...
  66. ncbi request reprint Screen-detected diabetes, hypertension and hypercholesterolemia as predictors of cardiovascular mortality in five populations of Asian origin: the DECODA study
    Tomoko Nakagami
    Diabetes Center, Tokyo Women s Medical University, Tokyo, Japan
    Eur J Cardiovasc Prev Rehabil 13:555-61. 2006
    ..The aims of this study were to assess the predictive value of glucose tolerance status as a risk factor for CVD and identify a high-risk group for fatal CVD in population-based studies of Asians...
  67. ncbi request reprint Slowly progressive insulin-dependent diabetes mellitus associated with pernicious anemia
    Jun Kinoshita
    Department of Internal Medicine, Kawaguchi Municipal Medical Center, Kawaguchi
    Intern Med 49:155-9. 2010
    ..We report this case because patients with pernicious anemia and SPIDDM in the absence of PGAS are rare in Japan...
  68. ncbi request reprint Comparison of voglibose and nateglinide for their acute effects on insulin secretion and free fatty acid levels in OLETF rat portal blood after sucrose loading
    Yutaka Mori
    Department of Internal Medicine, National Higashi Utsunomiya Hospital, Kawachi gun, Tochigi, Japan
    Endocrine 23:39-43. 2004
    ..Short-term hypoglycemic effects of single dose voglibose and nateglinide were compared after sucrose loading in spontaneously diabetic Otsuka Long-Evans Tokushima fatty (OLETF) rats...
  69. ncbi request reprint Effects of urocortin II on neonatal rat cardiac myocytes and non-myocytes
    Keiichi Ikeda
    Department of Pharmacology I, Jikei University School of Medicine, 3 25 8 Nishishinbashi, Tokyo 105 8461, Japan
    Peptides 26:2473-81. 2005
    ..These results indicate that Ucn II may be another endogenous cardiovascular substance that acts via CRH-R2 and the cAMP-dependent PKA pathway...
  70. pmc Long-term mortality in nationwide cohorts of childhood-onset type 1 diabetes in Japan and Finland
    Keiko Asao
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Diabetes Care 26:2037-42. 2003
    ..This study compares mortality from type 1 diabetes in Japan and Finland and examines the effects of sex, age at diagnosis, and calendar time period of diagnosis on mortality...
  71. ncbi request reprint Painless thyroiditis complicated by acromegaly
    Takatoshi Saito
    Division of Diabetes, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo
    Intern Med 49:167-70. 2010
    ....
  72. ncbi request reprint 5-hydroxytryptamine synthesis in HL-1 cells and neonatal rat cardiocytes
    Keiichi Ikeda
    Department of Pharmacology I, Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Biochem Biophys Res Commun 328:522-5. 2005
    ..These findings definitively demonstrate that 5-HT is secreted from the myocytes of the heart and strongly implied that 5-HT might play a certain role in cardiac physiology...
  73. ncbi request reprint Identification and functional analysis of the novel S179R POU1F1 mutation associated with combined pituitary hormone deficiency
    Ichiro Miyata
    Department of Pediatrics, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Tokyo 105 8461, Japan
    J Clin Endocrinol Metab 91:4981-7. 2006
    ..Several mutations of the human gene (called POU1F1) have been shown to be responsible for a phenotype of combined pituitary hormone deficiency involving GH, prolactin (PRL), and TSH...
  74. ncbi request reprint Gene and cell-based therapy for diabetes mellitus: endocrine gene therapeutics
    Takashi Sasaki
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Institute of DNA Medicine, Jikei University School of Medicine, 3 25 8, Nishishinbashi, Minato ku, Tokyo 105 8461, Japan
    Endocr Pathol 14:141-4. 2003
    ..This novel approach should provide a feasible method for treatment of diabetes mellitus without the use of any toxic agent or of embryonic stem cells that involve ethical implications...
  75. ncbi request reprint Familial Graves' disease associated with type 1 diabetes
    Keiichiro Matoba
    Department of Internal Medicine, Jikei University School of Medicine, Tokyo
    Intern Med 48:701-4. 2009
    ..Familial clustering of Graves' disease and type 1 diabetes, and their tendency to occur together along with a similar clinical course suggest that their etiology may involve shared genetic factors...
  76. ncbi request reprint PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients
    Junko Yamamoto
    Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Hypertens Res 25:25-9. 2002
    ..In conclusion, no significant association was observed between PPARgamma2 substitution and insulin sensitivity in the present cohort of Japanese hypertensive patients...
  77. doi request reprint Lifestyle modification and prevention of type 2 diabetes in overweight Japanese with impaired fasting glucose levels: a randomized controlled trial
    Toshikazu Saito
    Department of Internal Medicine, Social Insurance Chuo General Hospital, Tokyo, Japan
    Arch Intern Med 171:1352-60. 2011
    ..We investigated the efficacy of lifestyle modification on type 2 diabetes incidence among those with impaired fasting glucose levels...
  78. doi request reprint Immunohistochemical analysis of 11-beta-hydroxysteroid dehydrogenase type 2 and glucocorticoid receptor in subclinical Cushing's disease due to pituitary macroadenoma
    Takanori Ebisawa
    Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8 Nishishinbashi, Minato ku, Tokyo 105 8461, Japan
    Endocr Pathol 19:252-60. 2008
    ....
  79. ncbi request reprint Long-term administration of highly purified eicosapentaenoic acid ethyl ester improves blood coagulation abnormalities and dysfunction of vascular endothelial cells in Otsuka Long-Evans Tokushima fatty rats
    Yutaka Mori
    Department of Internal Medicine, National Higashi Utsunomiya Hospital, Tochigi, Japan
    Endocr J 50:603-11. 2003
    ..These data demonstrate that EPA-E beneficially altered certain factors known to promote thrombosis and atherosclerosis in this animal model...
  80. ncbi request reprint Contribution of Rho A and Rho kinase to platelet-derived growth factor-BB-induced proliferation of vascular smooth muscle cells
    Masumi Kamiyama
    Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, Nishishinbashi, Minato ku, Tokyo 105 8461, Japan
    J Atheroscler Thromb 10:117-23. 2003
    ..On the basis of these data, we conclude that PDGF-BB stimulates the proliferation of VSMCs via the activation of Rho A. Rho kinase plays an important role in this process as an effector of Rho A...
  81. ncbi request reprint Acute liver damage and subsequent hypophosphatemia in malnourished patients: case reports and review of literature
    Takatoshi Saito
    Division of Diabetes and Endocrinology, Department of Medicine, The Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Int J Eat Disord 41:188-92. 2008
    ..The relationship between liver damage and subsequent hypophosphatemia in malnourished patients will be discussed...
  82. ncbi request reprint JIKEI HEART Study--a morbi-mortality and remodeling study with valsartan in Japanese patients with hypertension and cardiovascular disease
    Seibu Mochizuki
    Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo, Japan
    Cardiovasc Drugs Ther 18:305-9. 2004
    ....
  83. doi request reprint Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages
    Kenji Yamashiro
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8510, Japan
    Biochem Biophys Res Commun 398:284-9. 2010
    ....
  84. ncbi request reprint Cardiac expression of urocortin (Ucn) in diseased heart; preliminary results on possible involvement of Ucn in pathophysiology of cardiac diseases
    Keiichi Ikeda
    Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Mol Cell Biochem 252:25-32. 2003
    ....
  85. ncbi request reprint A case of acquired deficiency of pituitary GH, PRL and TSH, associated with type 1 diabetes mellitus
    Takatoshi Saito
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Endocr J 51:287-93. 2004
    ..We report here a rare case of SPIDDM with CPHD which might be caused by lymphocytic hypophysitis...
  86. ncbi request reprint The fasting plasma glucose cut-point predicting a diabetic 2-h OGTT glucose level depends on the phenotype
    Tomoko Nakagami
    Diabetes Res Clin Pract 55:35-43. 2002
    ..1 mmol/l. There seems to be ethnic differences with respect to optimal FPG cut-point, and different screening strategies may be necessary in different parts of the world...
  87. ncbi request reprint Age- and sex-specific prevalence of diabetes and impaired glucose regulation in 11 Asian cohorts
    Qing Qiao
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Diabetes Care 26:1770-80. 2003
    ..To report the age- and sex-specific prevalence of diabetes and impaired glucose regulation (IGR) according to revised World Health Organization criteria for diabetes in Asian populations...
  88. ncbi request reprint Combined use of fasting plasma glucose and glycated hemoglobin A1c in a stepwise fashion to detect undiagnosed diabetes mellitus
    Tomoko Nakagami
    Diabetes Center, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, Tokyo 162 8666, Japan
    Tohoku J Exp Med 213:25-32. 2007
    ..In conclusion, the screening test scenario, in which an OGTT would be followed by the combined use of FPG and HbA1c in a stepwise fashion according to the JNDSP guideline, was not effective in identifying people with undiagnosed DM...
  89. ncbi request reprint [Risk factors for the development of complications and long-term prognosis in childhood diabetes]
    Rimei Nishimura
    Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University, School of Medicine
    Nihon Rinsho 60:712-8. 2002
  90. ncbi request reprint The metabolic syndrome in children and adolescents
    Paul Zimmet
    International Diabetes Institute, Melbourne, Vic, Australia
    Lancet 369:2059-61. 2007
  91. ncbi request reprint Is the measurement of glycated hemoglobin A1c alone an efficient screening test for undiagnosed diabetes? Japan National Diabetes Survey
    Tomoko Nakagami
    Diabetes Center, Tokyo Women s Medical University, 8 1, Kawada cho, Shinjuku ku, Tokyo 162 8666, Japan
    Diabetes Res Clin Pract 76:251-6. 2007
    ..The measurement of HbA1c alone may be efficient to screen undiagnosed DM and the cut-off point of 5.6% might be proper with respect to screening tests properties for undiagnosed DM, and prediction of vascular complications in Japan...
  92. ncbi request reprint Effect of captopril or imidapril on the progression of diabetic nephropathy in Japanese with type 1 diabetes mellitus: a randomized controlled study (JAPAN-IDDM)
    Shigehiro Katayama
    Fourth Department of Medicine, Saitama Medical School, 38 Morohongo, Moroyamacho, Irumagun, Saitama 350 0495, Japan
    Diabetes Res Clin Pract 55:113-21. 2002
    ..to clarify and confirm the renoprotective effects of ACEIs in Japanese type 1 diabetics...
  93. ncbi request reprint The effect of glucose variability on the risk of microvascular complications in type 1 diabetes
    Louis Monnier
    Diabetes Care 30:185-6; author reply 187-8. 2007
  94. ncbi request reprint [Type 1 diabetes mellitus]
    Takashi Sasaki
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
    Nihon Rinsho . 2006
  95. ncbi request reprint Incidence of ESRD and survival after renal replacement therapy in patients with type 1 diabetes: a report from the Allegheny County Registry
    Rimei Nishimura
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Kidney Dis 42:117-24. 2003
    ..Little information is available regarding the long-term incidence of end-stage renal disease (ESRD) and survival after the introduction of renal replacement therapy (RRT) in patients with type 1 diabetes...
  96. ncbi request reprint The metabolic syndrome in children and adolescents - an IDF consensus report
    Paul Zimmet
    International Diabetes Institute, Melbourne, Victoria, Australia
    Pediatr Diabetes 8:299-306. 2007
  97. ncbi request reprint Normocytic normochromic anemia due to automatic neuropathy in type 2 diabetic patients without severe nephropathy: a possible role of microangiopathy
    Takatoshi Saito
    Department of Medicine, Division of Diabetes and Endocrinology, The Jikei University School of Medicine, 3 25 8 Nishishimbashi Minato ku, Tokyo 105 8461, Japan
    Diabetes Res Clin Pract 70:239-47. 2005
    ..Treatment with recombinant erythropoietin increased their hemoglobin and hematocrit levels. These common points have a possibility to be brought about by tubulointerstitial damage and microangiopathy may be involved in it...
  98. ncbi request reprint New body mass index criteria of central obesity for male Japanese
    Naoko Horie
    Department of Exercise Physiology, Utsunomiya University, Mine, Japan
    Tohoku J Exp Med 208:83-6. 2006
    ..It is necessary to lower a cut-off point for central obesity from BMI of 25 kg/m2 to 24 kg/m2...
  99. doi request reprint Guideline for management of postmeal glucose
    Antonio Ceriello
    Warwick Medical School, Clinical Science Research Institute, Clinical Science Building, University Hospital Walsgrave Campus, Clifford Bridge Road, Coventry CV2 2DX, UK
    Nutr Metab Cardiovasc Dis 18:S17-33. 2008
    ..This guideline reviews the evidence on the harmful effects of elevated postmeal glucose and makes recommendations on its treatment, assessment and targets...
  100. ncbi request reprint [Current evidence-based medicine for early intervention in diabetes]
    Hironari Sano
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
    Nihon Rinsho 66:2027-32. 2008
    ..Further studies are expected to show the best point of intervention during diabetic course in preventing from progression of diabetic stage and diabetic complications...
  101. ncbi request reprint The validity of body mass index criteria in obese school-aged children
    Hideaki Komiya
    Department of Exercise Physiology, Utsunomiya University, Utsunomiya, Japan
    Tohoku J Exp Med 214:27-37. 2008
    ....