Research Topics
| Tadayuki IwaseSummaryAffiliation: Jikei University School of Medicine Country: Japan Publications
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Detail Information
Publications
Development of a real-time PCR assay for the detection and identification of Staphylococcus capitis, Staphylococcus haemolyticus and Staphylococcus warneriTadayuki Iwase
Department of Microbiology II, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo 105 8461, Japan
J Med Microbiol 56:1346-9. 2007..These results indicate that this method is useful for the identification and quantitative analysis of S. capitis, S. haemolyticus and S. warneri...
Rapid identification and specific quantification of Staphylococcus epidermidis by 5' nuclease real-time polymerase chain reaction with a minor groove binder probeTadayuki Iwase
Department of Bacteriology, The Jikei University School of Medicine, Tokyo 105 8461, Japan
Diagn Microbiol Infect Dis 60:217-9. 2008..This method distinguished S. epidermidis from other staphylococci and specifically quantified the bacterium. This study shows that the method is useful for the identification and quantitative detection of S. epidermidis...
Isolation and identification of ATP-secreting bacteria from mice and humansTadayuki Iwase
Department of Bacteriology, The Jikei University School of Medicine, and Central Clinical Laboratory, Jikei University Hospital, 3 25 8, Nishi Shimbashi, Minato ku, Tokyo, 105 8461 Japan
J Clin Microbiol 48:1949-51. 2010..However, the ATP-secreting bacteria have not been isolated and identified. In the present study, we report that Enterococcus gallinarum, which is a vancomycin-resistant Gram-positive coccus isolated from mice and humans, secretes ATP...
Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonizationTadayuki Iwase
Department of Bacteriology, The Jikei University School of Medicine, Tokyo, 105 8461 Japan
Nature 465:346-9. 2010..These findings indicate that Esp hinders S. aureus colonization in vivo through a novel mechanism of bacterial interference, which could lead to the development of novel therapeutics to prevent S. aureus colonization and infection...
Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interactionShinya Sugimoto
Department of Bacteriology, The Jikei University School of Medicine, Tokyo, Japan
J Bacteriol 195:1645-55. 2013..These results suggest that Esp inhibits S. aureus colonization and biofilm formation by degrading specific proteins that are crucial for biofilm construction and host-pathogen interaction...
Role of fibronectin-binding proteins A and B in in vitro cellular infections and in vivo septic infections by Staphylococcus aureusHitomi Shinji
Department of Bacteriology, The Jikei University School of Medicine, 3 25 8 Nishi shinbashi Minato ku, Tokyo 105 8461, Japan
Infect Immun 79:2215-23. 2011..The results showed that FnBPA is more important for in vitro and in vivo infections; however, cooperation between FnBPA and FnBPB is indispensable for the induction of severe infection resulting in septic death...
Inhibition of endothelial interleukin-8 production and neutrophil transmigration by Staphylococcus aureus beta-hemolysinAkiko Tajima
Department of Bacteriology, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo 105 8461, Japan
Infect Immun 77:327-34. 2009..These results showed that beta-hemolysin produced by S. aureus interferes with inflammatory signaling in endothelial cells and may help S. aureus evade the host immune response...
Expression and distribution of very late antigen-5 in mouse peritoneal macrophages upon ingestion of fibronectin-bound Staphylococcus aureusHitomi Shinji
Department of Microbiology II, The Jikei University School of Medicine, Tokyo, Japan
Microbiol Immunol 51:63-71. 2007..Together with our previous work, these results indicate that, upon ingestion of fibronectin-bound S. aureus, VLA-5 accumulates in the area of phagocytosis in inflammatory macrophages, where it forms adhesion complexes...
Glucose triggers ATP secretion from bacteria in a growth-phase-dependent mannerIppei Hironaka
Department of Bacteriology, The Jikei University School of Medicine, Minato ku, Japan
Appl Environ Microbiol 79:2328-35. 2013..These results suggest that various gut bacteria, including commensals and pathogens, might secrete ATP at any growth phase and modulate immune cell function...
