Takashi Yashiro


Affiliation: Jichi Medical School
Country: Japan


  1. Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kouki T, Kikuchi M, et al. Folliculostellate cell interacts with pericyte via TGF?2 in rat anterior pituitary. J Endocrinol. 2016;229:159-70 pubmed publisher
    ..TGF?2-mediated folliculostellate cell-pericyte interaction appears to be essential for collagen synthesis in rat anterior pituitary. This finding sheds new light on local cell-ECM interactions in the gland. ..
  2. request reprint
    Tofrizal A, Fujiwara K, Yashiro T, Yamada S. Alterations of collagen-producing cells in human pituitary adenomas. Med Mol Morphol. 2016;49:224-232 pubmed
    ..These results suggest that changes in the number and type of collagen-producing cells influence ECM arrangement, which may in turn reflect pathologic characteristics in pituitary adenomas. ..
  3. Jindatip D, Fujiwara K, Sarachana T, Mutirangura A, Yashiro T. Characteristics of pericytes in diethylstilbestrol (DES)-induced pituitary prolactinoma in rats. Med Mol Morphol. 2018;51:147-155 pubmed publisher
    ..This study is the first to clarify fine structural changes of pericytes in rat prolactinomas and improves our understanding of the function of pericytes under pathological conditions. ..
  4. Fujiwara K, Yatabe M, Tofrizal A, Jindatip D, Yashiro T, Nagai R. Identification of M2 macrophages in anterior pituitary glands of normal rats and rats with estrogen-induced prolactinoma. Cell Tissue Res. 2017;368:371-378 pubmed publisher
    ..Moreover, the number of M2 macrophages was greatly increased in rats with DES-induced prolactinoma. Future studies should attempt to characterize the functional role of M2 macrophages in the gland. ..
  5. Tofrizal A, Fujiwara K, Azuma M, Kikuchi M, Jindatip D, Yashiro T, et al. Tissue inhibitors of metalloproteinase-expressing cells in human anterior pituitary and pituitary adenoma. Med Mol Morphol. 2017;50:145-154 pubmed publisher
    ..These results suggest that TIMPs are important in the maintenance of ECM in human pituitary and that TIMP expressions are altered in fibrosis associated with pituitary adenoma. ..