Toshiyuki Yamada

Summary

Affiliation: Jichi Medical School
Country: Japan

Publications

  1. ncbi request reprint AA amyloid quantification in biopsy samples from the stomach
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical University, Yakushiji, Shimotsuke, Tochigi, Japan
    Ann Clin Lab Sci 42:3-6. 2012
  2. ncbi request reprint [Current status regarding detection of monoclonal component in Japan]
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke 329 0498, Japan
    Rinsho Byori 58:397-400. 2010
  3. ncbi request reprint The correlation between serum amyloid A and reactive oxygen metabolites in a young Mongolian population
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke City, Tochigi, Japan
    Ethn Dis 22:329-34. 2012
  4. ncbi request reprint The correlation between CVR-R and carotid atherosclerosis in type 2 diabetes mellitus patients with diabetic neuropathy
    Michiaki Miyamoto
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
    J Physiol Anthropol 29:149-52. 2010
  5. pmc The relationship between oxidized lipoprotein(a) and carotid atherosclerosis in asymptomatic subjects: a comparison with native lipoprotein(a)
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Lipids Health Dis 10:174. 2011
  6. doi request reprint Comparative study of the cardio-ankle vascular index and ankle-brachial index between young Japanese and Mongolian subjects
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Hypertens Res 32:140-4. 2009
  7. ncbi request reprint Influence of atorvastatin on serum amyloid A-low density lipoprotein complex in hypercholesterolemic patients
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi 320 0498, Japan
    Pharmacol Rep 64:212-6. 2012
  8. pmc The association between blood glucose and oxidized lipoprotein(a) in healthy young women
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Lipids Health Dis 9:103. 2010
  9. ncbi request reprint Determinants of carotid atherosclerosis in the general Mongolian population
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Ethn Dis 20:257-60. 2010
  10. doi request reprint The effects of lifestyle modification on a new oxidized low-density lipoprotein marker, serum amyloid A-LDL, in subjects with primary lipid disorder
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi 329 0498, Japan
    Clin Chim Acta 409:67-9. 2009

Collaborators

Detail Information

Publications29

  1. ncbi request reprint AA amyloid quantification in biopsy samples from the stomach
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical University, Yakushiji, Shimotsuke, Tochigi, Japan
    Ann Clin Lab Sci 42:3-6. 2012
    ..Among the amyloid-positive patients, the AA values correlated significantly with histological findings. This method may be useful for the quantitative evaluation of AA amyloidosis...
  2. ncbi request reprint [Current status regarding detection of monoclonal component in Japan]
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke 329 0498, Japan
    Rinsho Byori 58:397-400. 2010
    ..The detection of BJP in urine is still important. Capillary electrophoresis combined with immunoabsorption can detect BJP in non-concentrated urine. It may be time to take such new methods into consideration in Japan...
  3. ncbi request reprint The correlation between serum amyloid A and reactive oxygen metabolites in a young Mongolian population
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke City, Tochigi, Japan
    Ethn Dis 22:329-34. 2012
    ..Our study investigated the correlation among the d-ROMs test (a measure of the total oxidant capacity of blood), serum amyloid A (SAA) and high-sensitivity C-reactive protein (hs-CRP) levels in a young Mongolian population...
  4. ncbi request reprint The correlation between CVR-R and carotid atherosclerosis in type 2 diabetes mellitus patients with diabetic neuropathy
    Michiaki Miyamoto
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
    J Physiol Anthropol 29:149-52. 2010
    ..042), but not CVR-R(rest) or CVR-R(breath), in multivariate analyses adjusted for all the data. Therefore, the CVR-R(dif) may serve as a clinical index for the diabetic autonomic neuropathy-atherosclerosis relation in type 2 DM patients...
  5. pmc The relationship between oxidized lipoprotein(a) and carotid atherosclerosis in asymptomatic subjects: a comparison with native lipoprotein(a)
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Lipids Health Dis 10:174. 2011
    ..This study aimed to investigate the association between the serum oxLp(a) and carotid artery intima-media thickness (CIMT), in comparison to the serum Lp(a) levels, among asymptomatic subjects...
  6. doi request reprint Comparative study of the cardio-ankle vascular index and ankle-brachial index between young Japanese and Mongolian subjects
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Hypertens Res 32:140-4. 2009
    ..28) showed a correlation in the Japanese subjects. These results suggest that Mongolian subjects may be at higher risk of CVD, even among younger individuals, than Japanese subjects...
  7. ncbi request reprint Influence of atorvastatin on serum amyloid A-low density lipoprotein complex in hypercholesterolemic patients
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi 320 0498, Japan
    Pharmacol Rep 64:212-6. 2012
    ..The results suggest that atorvastatin may beneficially reduce SAA-LDL, and SAA-LDL may be a sensitive measure for monitoring the efficacy and antioxidant functions of atorvastatin...
  8. pmc The association between blood glucose and oxidized lipoprotein(a) in healthy young women
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Lipids Health Dis 9:103. 2010
    ..The aim of this study was to investigate the association between circulating oxLp(a) and cardiometabolic variables including blood glucose in healthy volunteers within the normal range of blood glucose...
  9. ncbi request reprint Determinants of carotid atherosclerosis in the general Mongolian population
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Ethn Dis 20:257-60. 2010
    ..The present population-based survey was a cross-sectional investigation of the determinants of carotid IMT in the general Mongolian population...
  10. doi request reprint The effects of lifestyle modification on a new oxidized low-density lipoprotein marker, serum amyloid A-LDL, in subjects with primary lipid disorder
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi 329 0498, Japan
    Clin Chim Acta 409:67-9. 2009
    ..Our aim was to investigate the effects of lifestyle modification on serum amyloid A-LDL (SAA-LDL), a new oxLDL, in subjects with primary lipid disorder...
  11. doi request reprint Association between reactive oxygen metabolites and paraoxonase 1 activity during a physical activity increase intervention with older Japanese people
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Australas J Ageing 31:222-6. 2012
    ....
  12. doi request reprint The correlation between the cardio-ankle vascular index (CAVI) and serum amyloid A in asymptomatic Japanese subjects
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
    Heart Vessels 27:499-504. 2012
    ..SAA may be a positive inflammatory factor associated with arterial stiffness, and the clinical relevance and the biological mechanism for this relationship should be established in future studies...
  13. ncbi request reprint [Common carotid arterial diameter and coronary artery disease]
    Michiaki Miyamoto
    Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke 329 0498, Japan
    Rinsho Byori 59:643-8. 2011
    ..50 (95% confidence interval = 1.71-11.84, p < 0.01), and the ratio were not largely altered in multivariate logistic regression analyses. The CCA diameter may therefore serve as a useful predictive marker for CAD in men...
  14. doi request reprint The relationship between serum C-reactive protein and daily physical activity in Japanese hypertensive patients
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Clin Exp Hypertens 32:517-22. 2010
    ..05). The data suggest that regular physical activity could reduce the CRP levels in HT patients, thereby maybe preventing CVD...
  15. doi request reprint Oxidative stress and metabolic syndrome in a Japanese female population
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Australas J Ageing 31:124-7. 2012
    ..The aim of the present study was to investigate the possible association between oxidative stress as evaluated by the d-ROMs test and the MetS component number, in a Japanese female population...
  16. doi request reprint Differential affinity of serum amyloid A1 isotypes for high-density lipoprotein
    Toshiyuki Yamada
    Department of Clinical and Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Amyloid 16:196-200. 2009
    ..5 allele at the SAA1 locus. These results suggest that the relatively high affinity of SAA1.5 may cause the high serum concentration and may be related to the low susceptibility to amyloidosis...
  17. ncbi request reprint Educational courses for physiological function examination at Jichi Medical University: practical trainings in ultrasonography
    Kiyoka Omoto
    1st Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama 330 8503, Japan
    Rinsho Byori 59:776-80. 2011
    ..The aims and the specifics of the trainings adopted in the seminar of ultrasound and the required or the optional subjects of Bedside Learning (BSL) at Jichi Medical University are reported...
  18. pmc The association between adiponectin, HDL-cholesterol and α1-antitrypsin-LDL in female subjects without metabolic syndrome
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Lipids Health Dis 9:147. 2010
    ..The aim of the present study was to investigate the association between AT-LDL and anti-atherosclerotic variables such as HDL-cholesterol and adiponectin in subjects with and without metabolic syndrome (MetS)...
  19. doi request reprint Oxidized lipoprotein(a) and cardio-ankle vascular index (CAVI) in hypertensive subjects
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, 329 0498, Japan
    Heart Vessels 28:461-6. 2013
    ..These findings suggest that the oxidative modification of Lp(a) may be associated with arterial stiffness in hypertensive, but not non-hypertensive, female subjects...
  20. ncbi request reprint Arterial wall elasticity measured using the phased tracking method and atherosclerotic risk factors in patients with type 2 diabetes
    Michiaki Miyamoto
    Department of Clinical Laboratory Medicine, Jichi Medical University
    J Atheroscler Thromb 20:678-87. 2013
    ..Conclusions: Upper limb AWE measurement can reflect the degree of atherosclerosis risk overload and may be useful for evaluating vascular complications in T2DM patients. ..
  21. pmc Influence of Physical Activity Intervention on Circulating Soluble Receptor for Advanced Glycation end Products in Elderly Subjects
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    J Clin Med Res 3:252-7. 2011
    ....
  22. doi request reprint Relationship between reactive oxygen metabolites and carotid intima-media thickness in subjects with hypercholesterolemia
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Med Princ Pract 19:496-8. 2010
    ..It was the aim of this study to investigate whether there is any relationship between oxidative stress, as assessed by the diacron reactive oxygen metabolite (d-ROM) test, and carotid atherosclerosis among hypercholesterolemic patients...
  23. doi request reprint Serum amyloid A upsurge precedes standard biomarkers of hepatotoxicity in ritodrine-injected mice
    Hiroyoshi Tsuchiya
    Division of Molecular Pharmacology, Department of Pharmacology, Jichi Medical University, Tochigi 329 0498, Japan
    Toxicology 305:79-88. 2013
    ..Therefore, our study provides a method for sensitive and early detection of hepatic injury, and may thus help preclude serious liver damage due to ritodrine use in preterm labor...
  24. pmc Serum cholesterol concentration associated with aspirin esterase activity in older people: preliminary data
    Kazuhiko Kotani
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    Int J Med Sci 7:90-3. 2010
    ..The objective of this study was to investigate the effects of cardio-metabolic variables such as cholesterol on serum aspirin esterase activity in older people who participated in an intervention study on physical activity...
  25. doi request reprint Oxidized high-density lipoprotein is associated with increased plasma glucose in non-diabetic dyslipidemic subjects
    Kazuhiko Kotani
    Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto City, Kyoto 612 8555, Japan
    Clin Chim Acta 414:125-9. 2012
    ..This study investigated the association of oxHDL with plasma glucose (PG) and the other atherosclerotic risk variables in non-diabetic dyslipidemic subjects...
  26. ncbi request reprint [Serum amyloid A (SAA)--pathogenicity and implication of appearance in plasma]
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical School, Shimotsuke, Tochigi 329 0498
    Rinsho Byori 54:509-12. 2006
    ..Therefore, it is possible that some parts of SAA in non-inflamed plasma are derived from extrahepatic sites such as adipose tissues and cells in the vascular wall...
  27. ncbi request reprint Immunotargeting of apolipoprotein E in amyloid: an initial trial in mice
    Toshiyuki Yamada
    Department of Clinical Laboratory Medicine, Jichi Medical University, 3311 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
    Ann Clin Lab Sci 39:134-7. 2009
    ..The results of this initial study are encouraging, but considerable improvement is necessary, particularly in regard to development of a high affinity antibody...
  28. ncbi request reprint Comparative study of atherosclerotic parameters in Mongolian and Japanese patients with hypertension and diabetes mellitus
    Shuumarjav Uurtuya
    Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Japan
    J Atheroscler Thromb 17:181-8. 2010
    ..Our study objective was to examine atherosclerotic profiles in HT and DM patients in both countries...
  29. ncbi request reprint Serum amyloid A (SAA) concentration varies among rheumatoid arthritis patients estimated by SAA/CRP ratio
    Masae Kokubun
    Department of Clinical Laboratory Medicine, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960 1247, Japan
    Clin Chim Acta 360:97-102. 2005
    ..SAA levels are generally higher and vary more among individuals. The significance of the SAA/CRP ratio was evaluated in the estimation of SAA...