Affiliation: Jichi Medical School
- The role of chromatin reorganization in the process of cellular senescenceKaoru Tominaga
Division of Functional Biochemistry, Department of Biochemistry, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
Curr Drug Targets 13:1593-602. 2012..Here, we review the molecular basis of the cell cycle arrest in cellular senescence, focusing on chromatin regulation. We also summarize our current knowledge of the role of cellular senescence in vivo...