T Onaka

Summary

Affiliation: Jichi Medical School
Country: Japan

Publications

  1. ncbi request reprint [Stress and its neural mechanisms]
    Tatsushi Onaka
    Nihon Yakurigaku Zasshi 126:170-3. 2005
  2. doi request reprint Roles of oxytocin neurones in the control of stress, energy metabolism, and social behaviour
    T Onaka
    Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University, Shinotsuke shi, Tochigi ken, Japan
    J Neuroendocrinol 24:587-98. 2012
  3. ncbi request reprint Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus
    Tatsushi Onaka
    Department of Physiology, Jichi Medical School, Tochigi Ken 329 0498, Japan
    Eur J Neurosci 18:3018-26. 2003
  4. ncbi request reprint Neural pathways controlling central and peripheral oxytocin release during stress
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 16:308-12. 2004
  5. ncbi request reprint Involvement of N-methyl-D-aspartic acid receptor activation in oxytocin and vasopressin release after osmotic stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 13:166-74. 2001
  6. ncbi request reprint Catecholaminergic mechanisms underlying neurohypophysial hormone responses to unconditioned or conditioned aversive stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Tochigi ken, Japan
    Exp Physiol 85:101S-110S. 2000
  7. ncbi request reprint Galanin-like peptide stimulates vasopressin, oxytocin and adrenocorticotropic hormone release in rats
    Tatsushi Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi Ken 329 0498, Japan
    Neuroreport 16:243-7. 2005
  8. ncbi request reprint Role of noradrenergic projections to the bed nucleus of the stria terminalis in neuroendocrine and behavioral responses to fear-related stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi Ken 329 0498, Japan
    Brain Res 788:287-93. 1998
  9. ncbi request reprint Intermittent footshock facilitates dendritic vasopressin release but suppresses vasopressin synthesis within the rat supraoptic nucleus
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 15:629-32. 2003
  10. doi request reprint Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats
    H Suzuki
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Neuroendocrinol 21:183-90. 2009

Collaborators

Detail Information

Publications53

  1. ncbi request reprint [Stress and its neural mechanisms]
    Tatsushi Onaka
    Nihon Yakurigaku Zasshi 126:170-3. 2005
  2. doi request reprint Roles of oxytocin neurones in the control of stress, energy metabolism, and social behaviour
    T Onaka
    Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University, Shinotsuke shi, Tochigi ken, Japan
    J Neuroendocrinol 24:587-98. 2012
    ..Stress, obesity and social isolation are major risk factors for mortality in humans. Thus, the oxytocin-oxytocin receptor system is a therapeutic target for the promotion of human health...
  3. ncbi request reprint Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus
    Tatsushi Onaka
    Department of Physiology, Jichi Medical School, Tochigi Ken 329 0498, Japan
    Eur J Neurosci 18:3018-26. 2003
    ..These data suggest that dendritic oxytocin facilitates activation of oxytocin neurons, at least in part by augmentation of noradrenaline release via a presynaptic action...
  4. ncbi request reprint Neural pathways controlling central and peripheral oxytocin release during stress
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 16:308-12. 2004
    ..Roles of dendritic oxytocin release during stress and metabolic factors affecting stress pathways are also discussed...
  5. ncbi request reprint Involvement of N-methyl-D-aspartic acid receptor activation in oxytocin and vasopressin release after osmotic stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 13:166-74. 2001
    ..p.) facilitated glutamic acid release in and near the OVLT. The results support the view that NMDA receptor in the AV3V region modulates in a facilitative fashion the AV3V inputs to the supraoptic neurosecretory neurones...
  6. ncbi request reprint Catecholaminergic mechanisms underlying neurohypophysial hormone responses to unconditioned or conditioned aversive stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Tochigi ken, Japan
    Exp Physiol 85:101S-110S. 2000
    ..It is also suggested that noradrenergic neurones are functionally heterogeneous in the control of oxytocin release...
  7. ncbi request reprint Galanin-like peptide stimulates vasopressin, oxytocin and adrenocorticotropic hormone release in rats
    Tatsushi Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi Ken 329 0498, Japan
    Neuroreport 16:243-7. 2005
    ..It is possible that galanin-like peptide is involved in vasopressin, oxytocin and adrenocorticotropic hormone release from the pituitary during stress...
  8. ncbi request reprint Role of noradrenergic projections to the bed nucleus of the stria terminalis in neuroendocrine and behavioral responses to fear-related stimuli in rats
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi Ken 329 0498, Japan
    Brain Res 788:287-93. 1998
    ....
  9. ncbi request reprint Intermittent footshock facilitates dendritic vasopressin release but suppresses vasopressin synthesis within the rat supraoptic nucleus
    T Onaka
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    J Neuroendocrinol 15:629-32. 2003
    ..The data also suggest differential control of dendritic vasopressin release and synthesis in the hypothalamus...
  10. doi request reprint Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats
    H Suzuki
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Neuroendocrinol 21:183-90. 2009
    ..These results suggest that the increases in the concentrations of ACTH and corticosterone in AA rats are induced by hypothalamic AVP, based on data from AVP-eGFP transgenic rats...
  11. ncbi request reprint A selective role of brainstem noradrenergic neurons in oxytocin release from the neurohypophysis following noxious stimuli in the rat
    T Onaka
    Department of Physiology, Jichi Medical School, Tochigi ken, Japan
    Neurosci Res 25:67-75. 1996
    ..These results demonstrate that brainstem noradrenergic neurons mediate oxytocin release following noxious stimuli in the rat and suggest that responsible noradrenergic neurons are the A1 cells in the caudal ventrolateral medulla...
  12. ncbi request reprint Medullary A1 noradrenergic neurones may mediate oxytocin release after noxious stimuli
    T Onaka
    Department of Physiology, Division of Endocrinology and Metabolism, Jichi Medical School, Minamikawachi-machi, Tochigi-Ken 329-0498, Japan
    Neuroreport 12:2499-502. 2001
    ..From these and reported data, we conclude that the medullary A1 noradrenergic neurones contribute, at least in part, to oxytocin release from the pituitary after noxious stimuli...
  13. ncbi request reprint Role of NMDA receptors in the emotional memory associated with neuroendocrine responses to conditioned fear stimuli in the rat
    K Yagi
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan
    Neurosci Res 30:279-86. 1998
    ..The results suggest that an activation of NMDA receptors are required to acquire and recall but not to consolidate or retain the emotional memory associated with VP, OT and PRL responses to conditioned fear stimuli...
  14. ncbi request reprint Chronic osmotic stimuli increase salusin-beta-like immunoreactivity in the rat hypothalamo-neurohypophyseal system: possible involvement of salusin-beta on [Ca2+]i increase and neurohypophyseal hormone release from the axon terminals
    T Saito
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Neuroendocrinol 20:207-19. 2008
    ..Our results suggest that salusin-beta may be involved in the regulation of body fluid balance by stimulating neurohypophyseal hormone release from nerve endings by an autocrine/paracrine mechanism...
  15. ncbi request reprint Facilitation of Ca2+ store-dependent noradrenaline release after an N-methyl-D-aspartate receptor antagonist in the rat supraoptic nucleus
    X Liu
    Department of Physiology, Jichi Medical School, Minamikawachi-machi, Tochigi-ken, Japan
    J Neuroendocrinol 13:894-904. 2001
    ..These data are consistent with the hypothesis that activation of an NMDA receptor inhibits an intracellular Ca2+ store-dependent noradrenaline release from nerve terminals in the SON...
  16. ncbi request reprint Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats
    M Kawasaki
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    J Neuroendocrinol 19:54-65. 2007
    ..p. administration of 2-B4O may be associated with the inhibition of AA in rats...
  17. ncbi request reprint Facilitative role of prolactin-releasing peptide neurons in oxytocin cell activation after conditioned-fear stimuli
    L L Zhu
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi Ken 329 0498, Japan
    Neuroscience 118:1045-53. 2003
    ..From these data, we conclude that PrRP neurons in the dorsomedial medulla that project to the hypothalamus play a facilitative role in oxytocin release after emotional stimuli in rats...
  18. ncbi request reprint Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleus
    T Mera
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Kitakyushu 807 8555, Japan
    Neuroscience 141:1069-86. 2006
    ..These results suggest that prolactin-releasing peptide is a potent and important mediator of the stress response in the brain through the hypothalamic paraventricular nucleus...
  19. ncbi request reprint Vasopressin differentially modulates noradrenaline release in the rat supraoptic nucleus
    T Yamashita
    Department of Physiology, Jichi Medical School, Tochigi-Ken 329-0498, Japan
    Neuroreport 12:3509-11. 2001
    ..The results suggest that dendritically released vasopressin modulates noradrenaline release within the supraoptic nucleus in a bimodal fashion...
  20. ncbi request reprint Nicotine facilitates noradrenaline release in the rat supraoptic nucleus
    X Liu
    Department of Physiology, Jichi Medical School, Japan
    Neuroreport 12:641-3. 2001
    ..The results suggest that nicotine acts within the supraoptic nucleus to facilitate noradrenaline release pre-synaptically. This presynaptic action may contribute, in part, to vasopressin release after nicotine...
  21. ncbi request reprint Role of adrenoceptors in vasopressin, oxytocin and prolactin responses to conditioned fear stimuli in the rat
    C J Zou
    Department of Physiology, Jichi Medical School, Japan
    J Neuroendocrinol 10:905-10. 1998
    ..We conclude that alpha1 adrenoceptors play a facilitative role in VP, OT, PRL responses to conditioned fear stimuli...
  22. ncbi request reprint Involvement of medullary A2 noradrenergic neurons in the activation of oxytocin neurons after conditioned fear stimuli
    Lingling Zhu
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi ken, Japan 329 0498
    Eur J Neurosci 16:2186-98. 2002
    ....
  23. ncbi request reprint Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding
    Daisuke Kohno
    Division of Integrative Physiology, Department of Physiology, Jichi Medical University, School of Medicine, Tochigi 329 0498, Japan
    Endocrinology 149:1295-301. 2008
    ..Feeding-activated nesfatin-1 neurons in the PVN and SON could play a role in the postprandial regulation of feeding behavior and energy homeostasis...
  24. ncbi request reprint The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats
    Makoto Kawasaki
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Kitakyushu 807 8555, Japan
    Brain Res 1086:133-41. 2006
    ..p. administration of 2-B4O. These results suggest that a peripherally administered high dose of 2-B4O activates OXT-secreting neurons in the hypothalamus through activation of NTS neurons, possibly as a result of a stress response...
  25. doi request reprint Leptin inhibits and ghrelin augments hypothalamic noradrenaline release after stress
    Akio Kawakami
    Division of Brain and Neurophysiology, Department of Physiology, Tochigi ken, Japan
    Stress 11:363-9. 2008
    ....
  26. doi request reprint Central endogenous vasopressin induced by central salt-loading participates in body fluid homeostasis through modulatory effects on neurones of the paraventricular nucleus in conscious rats
    K Kato
    Department of Physiology, National Defense Medical College, Saitama, Japan
    J Neuroendocrinol 21:921-34. 2009
    ..The parvocellular and magnocellular neurones in the PVN might show different responses to central salt-loading to maintain body fluid homeostasis as a result of the modulatory role of central endogenous AVP...
  27. doi request reprint Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotrophin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus
    M Toriya
    Division of Integrative Physiology, Department of Physiology, Jichi Medical University, Shimostuke, Tochigi, Japan
    J Neuroendocrinol 22:987-95. 2010
    ..These results indicate that the CRH-urocortin-CRH-R2 pathway in the PVN and connected areas mediates the long-term effects of BDNF to depress feeding and promote lipolysis...
  28. doi request reprint Oxytocin receptor-deficient mice developed late-onset obesity
    Yuki Takayanagi
    Department of Physiology, Jichi Medical University, Shimotsuke, Tochigi, Japan
    Neuroreport 19:951-5. 2008
    ..In contrast, brown adipose tissue in Oxtr-/- mice contained large lipid droplets and cold-induced thermogenesis was impaired. This study demonstrates that oxytocin receptor plays essential roles in the regulation of energy homeostasis...
  29. ncbi request reprint The differential effect of cyclosporine on hypnotic response and pain reaction in mice
    Yuki Sato
    Department of Anesthesiology, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
    Anesth Analg 105:1489-93, table of contents. 2007
    ..Recently, calcineurin-inhibitor-induced pain syndrome, characterized by severe pain in the lower limbs, has also been recognized in both organ and stem-cell transplantations...
  30. ncbi request reprint Hyperphagia and obesity in Na,K-ATPase alpha2 subunit-defective mice
    Kiyoshi Kawakami
    Division of Biology, Center for Molecular Medicine, Jichi Medical School, Yakushiji, Minamikawachi, Kawachi, Tochigi 329 0498 Japan
    Obes Res 13:1661-71. 2005
    ..The aim of this study was to examine whether Atp1a2-defective heterozygous mice show obesity and reveal the mechanisms underlying the obesity...
  31. ncbi request reprint Activation of orexin neurones after noxious but not conditioned fear stimuli in rats
    Lingling Zhu
    Department of Physiology, Jichi Medical School, Minamikawachi Machi, Tochigi 329 0498, Japan
    Neuroreport 13:1351-3. 2002
    ..This finding is consistent with an idea that orexin neurones are involved in stress-induced food intake...
  32. ncbi request reprint Centrally administered neuromedin U activates neurosecretion and induction of c-fos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat
    Yumi Ozaki
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807 8555, Japan
    Endocrinology 143:4320-9. 2002
    ..These results suggest that centrally administered NMU activates OXTergic cells in the PVN and SON predominantly as well as hypothalamo-pituitary adrenal axis...
  33. pmc Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary
    Akiko Katoh
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
    J Endocrinol 204:275-85. 2010
    ..These results suggest that our new transgenic rats are a valuable new tool to identify OXT-producing neurones and their terminals...
  34. ncbi request reprint Neuromedin U facilitates oxytocin release from the pituitary via beta adrenoceptors
    Kumiko Rokkaku
    Department of Medicine, Jichi Medical School, Tochigi ken, Japan
    Neuroreport 14:1997-2000. 2003
    ..All theses data suggest that neuromedin U stimulates oxytocin release from the pituitary, at least in part, via activation of beta adrenoceptors...
  35. ncbi request reprint Salt loading reduces hypothalamic noradrenaline release after noxious stimuli
    Yuki Takayanagi
    Department of Physiology, Jichi Medical School, Kawachi gun, Tochigi Ken 329 0498, Japan
    Neurosci Lett 391:22-7. 2005
    ..These data suggest that salt loading presynaptically suppresses noradrenaline release in the hypothalamus and oxytocin release into the blood after footshocks...
  36. pmc Endogenous prolactin-releasing peptide regulates food intake in rodents
    Yuki Takayanagi
    Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University, Shimotsuke, Tochigi, Japan
    J Clin Invest 118:4014-24. 2008
    ..These data suggest that PrRP relays satiety signals within the brain and that selective disturbance of this system can result in obesity and associated metabolic disorders...
  37. ncbi request reprint Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway
    Daisuke Kohno
    Department of Physiology, Division of Integrative Physiology, Jichi Medical University, School of Medicine, Tochigi 329 0498, Japan
    Endocrinology 148:2251-63. 2007
    ..This interaction may play an important role in regulating ARC NPY neuron activity and, thereby, feeding...
  38. doi request reprint Centrally administered relaxin-3 induces Fos expression in the osmosensitive areas in rat brain and facilitates water intake
    Hiroki Otsubo
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Peptides 31:1124-30. 2010
    ..These results suggest that icv administered relaxin-3 activates osmosensitive areas in the brain and plays an important role in the regulation of body fluid balance...
  39. pmc Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake
    M Yamashita
    Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University, Shimotsuke shi, Japan
    J Neuroendocrinol 25:455-65. 2013
    ..These findings suggest that PrRP mediates, at least in part, the activation of oxytocin neurones in response to food intake, and that the CCK-PrRP-oxytocin pathway plays an important role in the control of the termination of each meal...
  40. ncbi request reprint Effects of cholecystokinin (CCK)-8 on hypothalamic oxytocin-secreting neurons in rats lacking CCK-A receptor
    Hirofumi Hashimoto
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Auton Neurosci 121:16-25. 2005
    ..These results suggest that peripheral administration of CCK-8 may selectively activate the hypothalamic OXT-secreting neurons and brainstem neurons through CCK-A receptor in rats...
  41. ncbi request reprint Malfunction of respiratory-related neuronal activity in Na+, K+-ATPase alpha2 subunit-deficient mice is attributable to abnormal Cl- homeostasis in brainstem neurons
    Keiko Ikeda
    Division of Biology, Center for Molecular Medicine, Jichi Medical School, Kawachi, Tochigi 329 0498, Japan
    J Neurosci 24:10693-701. 2004
    ..Based on these results, we propose a model for functional coupling between the Na+, K+-ATPase alpha2 subunit and KCC2, which excludes Cl- from the cytosol in respiratory center neurons...
  42. ncbi request reprint Impact of cyclosporine upon emotional and social behavior in mice
    Yuki Sato
    Department of Anesthesiology, Jichi Medical University, Tochigi ken, Japan
    Transplantation 83:1365-70. 2007
    ..Cyclosporine induces psychological side effects but its mechanisms of action remain to be elucidated...
  43. ncbi request reprint Downregulation of prolactin-releasing peptide gene expression in the hypothalamus and brainstem of diabetic rats
    Takashi Mera
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Peptides 28:1596-604. 2007
    ..The diabetic condition and insulin-treatment may affect the regulation of PrRP gene expression via leptin and other factors, such as plasma glucose level. The diabetic condition may not impair the role of PrRP as a stress mediator...
  44. ncbi request reprint Galanin-like peptide stimulates food intake via activation of neuropeptide Y neurons in the hypothalamic dorsomedial nucleus of the rat
    Motoki Kuramochi
    Department of Physiology, Division of Integrative Physiology, Jichi Medical School, Minamikawachi, Kawachi, Tochigi, Japan
    Endocrinology 147:1744-52. 2006
    ..These data show that icv GALP injection induces a potent short-term stimulation of food intake mainly via activation of NPY-containing neurons in the DMN...
  45. ncbi request reprint Galanin-like peptide and ghrelin increase cytosolic Ca2+ in neurons containing growth hormone-releasing hormone in the arcuate nucleus
    Motoki Kuramochi
    Department of Physiology, Division of Integrative Physiology, Jichi Medical School, School of Medicine, Minamikawachi, Kawachi, Tochigi 329 0498, Japan
    Regul Pept 126:85-9. 2005
    ..The former action may be involved in the orexigenic effect of GALP and the latter in the GH-releasing and/or orexigenic effects ghrelin...
  46. doi request reprint Impairment of social and emotional behaviors in Cadm1-knockout mice
    Yuki Takayanagi
    Department of Physiology, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke shi, Tochigi Ken 329 0498, Japan
    Biochem Biophys Res Commun 396:703-8. 2010
    ....
  47. ncbi request reprint Involvement of novel feeding-related peptides in neuroendocrine response to stress
    Yoichi Ueta
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807 8555, Japan
    Exp Biol Med (Maywood) 228:1168-74. 2003
    ..The possible involvement of novel feeding-related peptides in neuroendocrine responses to stress is reviewed here...
  48. doi request reprint Metabolic and stress-related roles of prolactin-releasing peptide
    Tatsushi Onaka
    Department of Physiology, Jichi Medical University, Shimotsuke shi, Tochigi Ken 329 0498, Japan
    Trends Endocrinol Metab 21:287-93. 2010
    ..This review describes how prolactin-releasing peptide neurons receive information concerning both internal metabolic states and environmental conditions, and play a key role in energy homeostasis and stress responses...
  49. doi request reprint Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway
    Yuko Maejima
    Division of Integrative Physiology, Department of Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329 0498, Japan
    Cell Metab 10:355-65. 2009
    ..The present results reveal the nesfatin-1-operative oxytocinergic signaling in the PVN that triggers leptin-independent melanocortin-mediated anorexia...
  50. ncbi request reprint Degeneration of the amygdala/piriform cortex and enhanced fear/anxiety behaviors in sodium pump alpha2 subunit (Atp1a2)-deficient mice
    Keiko Ikeda
    Department of Biology Jichi Medical School, Kawachi, Tochigi 329 0498, Japan
    J Neurosci 23:4667-76. 2003
    ....
  51. ncbi request reprint Possible inhibitory role of prolactin-releasing peptide for ACTH release associated with running stress
    Nao Ohiwa
    Laboratory of Exercise Biochemistry, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Ibaraki, Japan
    Am J Physiol Regul Integr Comp Physiol 292:R497-504. 2007
    ..Here we provide a novel perspective on understanding of PrRP in the endocrine-metabolic response associated with running stress...
  52. ncbi request reprint Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats
    Makoto Kawasaki
    Departments of Physiology, University of Occupational and Environmental Health, Kitakyushu 807 8555, Japan
    J Endocrinol 190:213-23. 2006
    ..c.v. administration of NPW30 (2.8 nmol/rat). These results suggest that central NPW30 may be involved in the regulation of secretion of AVP and OXT in the magnocellular neurosecretory cells in the SON and PVN...
  53. pmc Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
    Yuki Takayanagi
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 1 1 Tsutsumidori Amamiyamachi, Aoba ku, Sendai, Miyagi 981 8555, Japan
    Proc Natl Acad Sci U S A 102:16096-101. 2005
    ..Our studies demonstrate that OXTR plays a critical role in regulating several aspects of social behavior and may have important implications for developmental psychiatric disorders characterized by deficits in social behavior...