Research Topics
| S IdeiSummaryAffiliation: Jichi Medical School Country: Japan Publications
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Detail Information
Publications
Postoperative endocrine alterations and clinical outcome of infertile women with polycystic ovary syndrome after transvaginal hydrolaparoscopic ovarian drillingHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan
Fertil Steril 85:244-6. 2006..Postoperative endocrinological alterations following THLOD show significant decrease of serum LH and testosterone concentrations...
Methods for direct and indirect antisperm antibody testingHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, and Center for Reproductive Medicine, Jichi Medical University Hospital, Shimotsuke, Tochigi, Japan
Methods Mol Biol 927:51-60. 2013..In males, an immunobead test or a mixed antiglobulin reaction test, which detects ASA directly on the sperm surface, is a screening test because of the nonspecific reaction...
Prediction of pregnancy by intrauterine insemination using CASA estimates and strict criteria in patients with male factor infertilityHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan
Int J Androl 27:63-8. 2004..These variables would be helpful when counselling patients before they make the decision to proceed with in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)-ET...
Serum matrix metalloproteinase and tissue inhibitor of metalloproteinase concentrations in infertile women achieved pregnancy following IVF-ETHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachimachi, Kawachi gun, Tochigi 329 0498, Japan
Am J Reprod Immunol 54:186-92. 2005..This study was performed to compare serum MMP and TIMP concentrations between patients with and without the establishment of pregnancy following ET...
Relationship between level of serum sperm immobilizing antibody and its inhibitory effect on sperm migration through cervical mucus in immunologically infertile womenHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, Tochigi, Japan
Am J Reprod Immunol 57:142-6. 2007..The aim of this study was to investigate whether the 50% sperm immobilization unit (SI50) titer, a quantitative measure of sperm immobilizing antibody, in patients' sera was correlated with the result of PCT...
Increase of multiple pregnancies caused by ovulation induction with gonadotropin in combination with metformin in infertile women with polycystic ovary syndromeHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, Tochigi, Japan
Fertil Steril 87:1487-90. 2007..After the introduction of metformin treatment for such cases, the use of gonadotropin in combination with metformin significantly increased the incidence of multiple pregnancies...
Establishment of criteria for elective single embryo transfer at day 2 or day 3 by analyzing cases with successful implantation of all embryos transferredHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, Japan
J Obstet Gynaecol Res 33:501-5. 2007..In the present study, criteria for elective single embryo transfer (eSET) at day 2 or day 3 were established by analyzing cases with successful implantation of all embryos transferred...
Major complications and outcome of diagnostic and operative transvaginal hydrolaparoscopyHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University and Center for Reproductive Medicine, Jichi Medical University Hospital, Yakushiji, Shimotsuke, Tochigi, Japan
J Obstet Gynaecol Res 33:705-9. 2007..The purpose of the present study was to examine the risk of diagnostic and operative THL according to two case studies with a literature review...
Diagnosis and treatment of immunologically infertile women with sperm-immobilizing antibodies in their seraHiroaki Shibahara
Department of Obstetrics and Gynecology, School of Medicine, Jichi Medical University, and Center for Reproductive Medicine, Jichi Medical University Hospital, Shimotisuke, Tochigi, Japan
J Reprod Immunol 83:139-44. 2009..Characterization of sperm-immobilizing antibodies may help in the identification and characterization of sperm specific antigens that can be used as candidate antigens for the development of sperm based contraceptive vaccines...
Relationships between Chlamydia trachomatis antibody titers and tubal pathology assessed using transvaginal hydrolaparoscopy in infertile womenHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Kawachi gun, Tochigi, Japan
Am J Reprod Immunol 50:7-12. 2003..This study was performed to investigate the relationships between Chlamydia trachomatis antibody titers and tubal pathology assessed using THL in infertile women...
Clinical significance of the Acridine Orange test performed as a routine examination: comparison with the CASA estimates and strict criteriaHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Kawachi gun, Tochigi, Japan
Int J Androl 26:236-41. 2003..The information obtained using the AO test was indicated to be useful in planning treatment strategy for infertile couples...
Analysis of factors associated with multinucleate formation in human IVFHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Kawachi gun, Tochigi, Japan
Int J Androl 26:211-4. 2003..However, prevention of multinucleate formation seems to be unnecessary because a higher successful IVF-ET outcome is expected as a result of the excellent fertilization rate in these patients...
Relationships between sperm motility characteristics assessed by the computer-aided sperm analysis (CASA) and fertilization rates in vitroY Hirano
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1, Yakushiji, Minamikawachi Machi, Tochigi 329 0498, Japan
J Assist Reprod Genet 18:213-8. 2001..This study was carried out to investigate the relationships between the CASA estimates and fertilization rates in vitro...
Usefulness of transvaginal hydrolaparoscopy in investigating infertile women with Chlamydia trachomatis infectionH Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1, Yakushiji, Minamikawachi Machi, Kawachi gun, Tochigi 329 0498, Japan
Hum Reprod 16:1690-3. 2001..This study was performed to investigate the usefulness of THL to evaluate Chlamydia trachomatis tubal infertility...
Activity of testis angiotensin converting enzyme (ACE) in ejaculated human spermatozoaH Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1 Yakushiji, Minami Kawachi Machi, Kawachi gun, Tochigi 329 0498, Japan
Int J Androl 24:295-9. 2001..05). These findings suggest that testicular ACE is released from normal functional spermatozoa for them to have fertilizing ability...
Two-dimensional electrophoretic analysis of sperm antigens recognized by sperm immobilizing antibodies detected in infertile womenHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1 Minamikawachi machi, Kawachi gun, Tochigi 329 0498, Japan
J Reprod Immunol 53:1-12. 2002..The coordinates of 4 prominent immunoreactive sperm proteins were considered as possibly relevant to antibody mediated female infertility...
Diversity of antisperm antibodies bound to sperm surface in male immunological infertilityHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan
Am J Reprod Immunol 47:146-50. 2002..This study was performed to investigate if there is diversity of ASA bound to sperm surface using immunobead test (IBT) combined with complement dependent sperm immobilization test (SIT)...
Effect of sperm-immobilizing antibodies bound to the surface of ejaculated human spermatozoa on sperm motility in immunologically infertile menHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan
Fertil Steril 79:641-2. 2003
Chemokine bioactivity of RANTES is elevated in the sera of infertile women with past Chlamydia trachomatis infectionHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan
Am J Reprod Immunol 49:169-73. 2003..Recently, association between some inflammatory diseases and chemokines has been investigated. This study was performed to clarify the relationship between chemokines in the sera of infertile women and past C. trachomatis infection...
Diversity of the inhibitory effects on fertilization by anti-sperm antibodies bound to the surface of ejaculated human spermHiroaki Shibahara
Department of Obstetrics and Gynecology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi Machi, Kawachi gun, Tochigi 329 0498, Japan
Hum Reprod 18:1469-73. 2003..However, it has been shown that there is a diversity of ASA bound to the sperm surface. This study was performed to investigate the inhibitory effects on fertilization by ASA in males...
Prediction of unexpectedly poor fertilization and pregnancy outcome using the strict criteria for sperm morphology before and after sperm separation in IVF-ETH Obara
Department of Obstetrics and Gynaecology, Jichi Medical School, Tochigi, Japan
Int J Androl 24:102-8. 2001..These results indicate that the strict criteria provide a reliable estimation of the fertilizing ability of human spermatozoa. ICSI might be considered in Category A patients to avoid poor fertilization and pregnancy outcome...
