Taiji Furukawa

Summary

Affiliation: Jichi Medical School
Country: Japan

Publications

  1. ncbi request reprint Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Kawachi gun, Tochigi, Japan
    Cancer 94:911-20. 2002
  2. ncbi request reprint An early stage small bowel adenocarcinoma with microsatellite instability phenotype in a case of hereditary nonpolyposis colorectal cancer
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Yakushiji 3311 1, Minamikawachi Machi, 329 0498, Tochigi, Japan
    Int J Colorectal Dis 18:267-70. 2003
  3. ncbi request reprint Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas
    Koji Koinuma
    Department of Surgery, Jichi Medical School, Tochigi, Japan
    Int J Cancer 108:237-42. 2004
  4. ncbi request reprint Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis
    Kazuhisa Shitoh
    Department of Surgery, Jichi Medical School, Tochigi ken, Japan
    Dig Dis Sci 49:1631-3. 2004
  5. ncbi request reprint Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Minamikawachimachi, Tochigi, Japan
    Genes Chromosomes Cancer 35:1-10. 2002
  6. ncbi request reprint The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration
    Nobuyuki Takemoto
    Department of Surgery, Omiya Medical Center, Jichi Medical School, Saitama, Japan
    Jpn J Clin Oncol 34:90-8. 2004
  7. ncbi request reprint Overexpression in colorectal carcinoma of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis
    Toshihiko Tsukamoto
    Department of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
    Cancer 106:1489-97. 2006

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Kawachi gun, Tochigi, Japan
    Cancer 94:911-20. 2002
    ..In this article, the authors evaluate retrospectively whether the JCC are adequate to diagnose HNPCC compared with the Bethesda guidelines (BG) and also investigated useful screening methods for HNPCC...
  2. ncbi request reprint An early stage small bowel adenocarcinoma with microsatellite instability phenotype in a case of hereditary nonpolyposis colorectal cancer
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Yakushiji 3311 1, Minamikawachi Machi, 329 0498, Tochigi, Japan
    Int J Colorectal Dis 18:267-70. 2003
    ..Small bowel carcinoma is included in the tumor spectrum of HNPCC, but the frequency of occurrence of this tumor in HNPCC patients is comparatively rare...
  3. ncbi request reprint Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas
    Koji Koinuma
    Department of Surgery, Jichi Medical School, Tochigi, Japan
    Int J Cancer 108:237-42. 2004
    ..PM or NM; p < 0.0001). These findings suggest that BRAF activation may participate in the carcinogenesis of sporadic CRCs with hMLH1 hypermethylation in the proximal colon, independently of KRAS activation...
  4. ncbi request reprint Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis
    Kazuhisa Shitoh
    Department of Surgery, Jichi Medical School, Tochigi ken, Japan
    Dig Dis Sci 49:1631-3. 2004
    ..Our results may support this report and suggest that some colorectal cancers with beta-catenin mutation will progress without K-ras mutation. Further study may disclose a new pathway or new mechanism of colorectal tumorigenesis...
  5. ncbi request reprint Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers
    Taiji Furukawa
    Department of Surgery, Jichi Medical School, Minamikawachimachi, Tochigi, Japan
    Genes Chromosomes Cancer 35:1-10. 2002
    ..5% (22/37). Overall, our data suggested that the type 1 methylation pattern may affect MLH1 mRNA expression, such that the majority of MSI-H cases in sporadic CRC, especially proximal colon cancer, exhibited type 1 methylation...
  6. ncbi request reprint The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration
    Nobuyuki Takemoto
    Department of Surgery, Omiya Medical Center, Jichi Medical School, Saitama, Japan
    Jpn J Clin Oncol 34:90-8. 2004
    ..However, there has been no fully adequate comparison of these two categories, especially analysis in relation to microsatellite instability (MSI)...
  7. ncbi request reprint Overexpression in colorectal carcinoma of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis
    Toshihiko Tsukamoto
    Department of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
    Cancer 106:1489-97. 2006
    ..Increased CLN2 activity has been reported in breast carcinoma and the antiapoptotic effect of another causative gene of NCL, ceroid lipofuscinosis, neuronal 1 (CLN1), is known...