Kazuo Eguchi

Summary

Affiliation: Jichi Medical School
Country: Japan

Publications

  1. ncbi request reprint Smoking is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population
    Kazuo Eguchi
    Department of Cardiology, Shioya General Hospital, Tochigi, Japan
    Hypertens Res 27:747-54. 2004
  2. ncbi request reprint Type 2 diabetes is associated with left ventricular concentric remodeling in hypertensive patients
    Kazuo Eguchi
    Department of Cardiology, Shioya General Hospital, Tochigi, Japan Department of Cardiology, Jichi Medical School, Tochigi ken, Japan
    Am J Hypertens 18:23-9. 2005
  3. ncbi request reprint Nocturnal hypoxia is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Am J Hypertens 18:1489-95. 2005
  4. ncbi request reprint Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Hypertens Res 27:235-41. 2004
  5. ncbi request reprint Comparison of valsartan and amlodipine on ambulatory and morning blood pressure in hypertensive patients
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi, Kawachi, Tochigi 329 0498, Japan
    Am J Hypertens 17:112-7. 2004
  6. ncbi request reprint Greater impact of coexistence of hypertension and diabetes on silent cerebral infarcts
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, 3311 1, Yakushiji, Minamikawachi, Kawachi, Tochigi, 329 0498, Japan
    Stroke 34:2471-4. 2003
  7. ncbi request reprint Comparison of candesartan with lisinopril on ambulatory blood pressure and morning surge in patients with systemic hypertension
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Am J Cardiol 92:621-4. 2003
  8. ncbi request reprint A case of vertebral artery dissection associated with morning blood pressure surge
    Kazuo Eguchi
    Department of Internal Medicine, Shioya General Hospital, Tochigi, Japan
    Hypertens Res 28:847-51. 2005
  9. ncbi request reprint Impact of blood pressure vs. glycemic factors on target organ damage in patients with type 2 diabetes mellitus
    Kazuo Eguchi
    Behavioral Cardiovascular Health and Hypertension Program, Columbia University Medical Center, New York, NY 10032, USA
    J Clin Hypertens (Greenwich) 8:404-10. 2006
  10. doi request reprint Monitoring of the central pulse pressure is useful for detecting cardiac overload during antiadrenergic treatment: the Japan Morning Surge 1 study
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 26:1928-34. 2008

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Smoking is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population
    Kazuo Eguchi
    Department of Cardiology, Shioya General Hospital, Tochigi, Japan
    Hypertens Res 27:747-54. 2004
    ..045) and SBP (beta =0.196, p =0.011) were independent determinants of the increased number of SCIs. In conclusion, smoking status was an independent determinant of multiple SCIs in a high-risk Japanese community-dwelling population...
  2. ncbi request reprint Type 2 diabetes is associated with left ventricular concentric remodeling in hypertensive patients
    Kazuo Eguchi
    Department of Cardiology, Shioya General Hospital, Tochigi, Japan Department of Cardiology, Jichi Medical School, Tochigi ken, Japan
    Am J Hypertens 18:23-9. 2005
    ..In this study, we investigated the impact of diabetes and ambulatory blood pressure (BP) on LV geometric remodeling in hyptensives with/without diabetes...
  3. ncbi request reprint Nocturnal hypoxia is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Am J Hypertens 18:1489-95. 2005
    ..The objective of this study was to investigate the relationship between nocturnal hypoxia and silent cerebral infarct (SCI) in the general population...
  4. ncbi request reprint Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Hypertens Res 27:235-41. 2004
    ..In conclusion, hypertensive patients with greater change of postural BP (OHT and OHYPO) were shown to have increased risk of advanced silent brain lesions and greater cardiac burden...
  5. ncbi request reprint Comparison of valsartan and amlodipine on ambulatory and morning blood pressure in hypertensive patients
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi, Kawachi, Tochigi 329 0498, Japan
    Am J Hypertens 17:112-7. 2004
    ..We aimed to study the effects of monotherapy with the long-acting angiotensin II receptor blocker valsartan compared with the long-acting calcium antagonist amlodipine on ambulatory and morning blood pressure (BP)...
  6. ncbi request reprint Greater impact of coexistence of hypertension and diabetes on silent cerebral infarcts
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, 3311 1, Yakushiji, Minamikawachi, Kawachi, Tochigi, 329 0498, Japan
    Stroke 34:2471-4. 2003
    ..The aim of this study was to evaluate the prevalence and determinants of SCI in hypertensives with or without diabetes mellitus (DM)...
  7. ncbi request reprint Comparison of candesartan with lisinopril on ambulatory blood pressure and morning surge in patients with systemic hypertension
    Kazuo Eguchi
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Am J Cardiol 92:621-4. 2003
    ....
  8. ncbi request reprint A case of vertebral artery dissection associated with morning blood pressure surge
    Kazuo Eguchi
    Department of Internal Medicine, Shioya General Hospital, Tochigi, Japan
    Hypertens Res 28:847-51. 2005
    ..We speculated that the acute rise of blood pressure in the early morning might have contributed to the dissection of the vertebral artery...
  9. ncbi request reprint Impact of blood pressure vs. glycemic factors on target organ damage in patients with type 2 diabetes mellitus
    Kazuo Eguchi
    Behavioral Cardiovascular Health and Hypertension Program, Columbia University Medical Center, New York, NY 10032, USA
    J Clin Hypertens (Greenwich) 8:404-10. 2006
    ..BP may be more important than glycemic factors for predicting future cardiovascular complications...
  10. doi request reprint Monitoring of the central pulse pressure is useful for detecting cardiac overload during antiadrenergic treatment: the Japan Morning Surge 1 study
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 26:1928-34. 2008
    ..We assessed the hypothesis that the change in the central PP is more useful than that in the brachial PP in the assessment of the change in cardiac load...
  11. doi request reprint Controlling evening BP as well as morning BP is important in hypertensive patients with prediabetes/diabetes: the JMS-1 study
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 23:522-7. 2010
    ..We aimed to test the hypotheses that home BP is more closely associated with target-organ damage than clinic BP, and that the presence of prediabetes/T2DM enhances the impact of home BP measurement...
  12. ncbi request reprint Adrenergic blockade improved insulin resistance in patients with morning hypertension: the Japan Morning Surge-1 Study
    Seiichi Shibasaki
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    J Hypertens 27:1252-7. 2009
    ..It has been demonstrated that insulin resistance is associated with morning hypertension. We investigated the hypothesis that the lowering of morning blood pressure (BP) can improve insulin resistance in patients with morning hypertension...
  13. doi request reprint An alpha-adrenergic blocker titrated by self-measured blood pressure recordings lowered blood pressure and microalbuminuria in patients with morning hypertension: the Japan Morning Surge-1 Study
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 26:1257-65. 2008
    ..The impact on microalbuminuria of strict treatment aimed at lowering of self-measured morning blood pressure using an adrenergic blockade is unclear...
  14. ncbi request reprint Cardiovascular risks of dipping status and chronic kidney disease in elderly Japanese hypertensive patients
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 10:787-94. 2008
    ..081). Patients with CKD have an increased risk of cardiovascular events. CKD and other cardiovascular risk factors may account for some of the increased risk in nondippers, but it does not explain the higher risk in extreme dippers...
  15. ncbi request reprint Age-specific impact of self-monitored pulse pressure on hypertensive target organ damage in treated hypertensive patients
    Kazuo Eguchi
    Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 9:522-9. 2007
    ..In the very old (older than 75 years), however, there were no consistent associations between pulse pressure measures and BNP. More studies are needed in the evaluation of cardiac risk with hemodynamic measures in the very old...
  16. ncbi request reprint Determinants of exaggerated difference in morning and evening blood pressure measured by self-measured blood pressure monitoring in medicated hypertensive patients: Jichi Morning Hypertension Research (J-MORE) Study
    Joji Ishikawa
    Division of Cardiology, Jichi Medial School, Tochigi, Japan
    Am J Hypertens 18:958-65. 2005
    ..We studied the determinants of the morning minus evening systolic BP difference (ME difference) in self-measured BP monitoring, as a possible risk factor for stroke in medicated hypertensive patients...
  17. ncbi request reprint Impact of arterial stiffness reduction on urinary albumin excretion during antihypertensive treatment: the Japan morning Surge-1 study
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 28:1752-60. 2010
    ..The aim of this study was to assess the association of the change in pulse wave velocity (PWV) with that in urinary albumin excretion as a measure of renal damage...
  18. doi request reprint Maximum value of home blood pressure: a novel indicator of target organ damage in hypertension
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, 3311 1 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
    Hypertension 57:1087-93. 2011
    ..002 and P<0.001, respectively). These findings indicate that assessment of the maximum home SBP, in addition to the mean home SBP, might increase the predictive value of hypertensive TOD in the heart and artery...
  19. ncbi request reprint Smoking and antihypertensive medication: interaction between blood pressure reduction and arterial stiffness
    Yoshio Matsui
    Department of Internal Medicine, Miwa Municipal Hospital, Yamaguchi, Japan
    Hypertens Res 28:631-8. 2005
    ..In the short term, cigarette smoking blunts the effect of amlodipine on the reduction of arterial stiffness, independently of the mean BP level...
  20. ncbi request reprint Effect of doxazosin on the left ventricular structure and function in morning hypertensive patients: the Japan Morning Surge 1 study
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 26:1463-71. 2008
    ..Doxazosin is reported to increase the incidence of congestive heart failure. The benefits of doxazosin, for controlling morning blood pressure as well as its effect on the left ventricular structure and function, are herein examined...
  21. pmc Night time blood pressure variability is a strong predictor for cardiovascular events in patients with type 2 diabetes
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan
    Am J Hypertens 22:46-51. 2009
    ....
  22. doi request reprint Masked hypertension defined by ambulatory blood pressure monitoring is associated with an increased serum glucose level and urinary albumin-creatinine ratio
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University, School of Medicine, 3311 1 Yakushiji, Shimotsuke, Tochigi, Japan
    J Clin Hypertens (Greenwich) 12:578-87. 2010
    ..009). Masked hypertension defined by 24-hour ambulatory BP is associated with an increased serum glucose level and urinary albumin-creatinine ratio, but these relationships are not observed in masked hypertension defined by HBP...
  23. ncbi request reprint Sleep pulse pressure and awake mean pressure as independent predictors for stroke in older hypertensive patients
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical School, 3311 1 Yakushiji, Minami Kawachi, Kawachi, Tochigi 329 0498, Japan
    Am J Hypertens 17:439-45. 2004
    ..It remains uncertain which is the stronger predictor for stroke in older hypertensives, ambulatory pulse pressure (PP) or mean blood pressure (MBP)...
  24. doi request reprint Is home blood pressure variability itself an interventional target beyond lowering mean home blood pressure during anti-hypertensive treatment?
    Satoshi Hoshide
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    Hypertens Res 35:862-6. 2012
    ..003) but was not associated with that of s.d. of home SBP or that of maximum home SBP. Home BP variability is not itself an interventional target beyond lowering mean home BP during anti-hypertensive treatment...
  25. pmc Short sleep duration as an independent predictor of cardiovascular events in Japanese patients with hypertension
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, Japan
    Arch Intern Med 168:2225-31. 2008
    ..It is not known whether short duration of sleep is a predictor of future cardiovascular events in patients with hypertension...
  26. doi request reprint Differential effects between a calcium channel blocker and a diuretic when used in combination with angiotensin II receptor blocker on central aortic pressure in hypertensive patients
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, 3311 1 Yakushiji, Shimotsuke, Tochigi, Japan
    Hypertension 54:716-23. 2009
    ..0 mg) and hydrochlorothiazide (12.5 mg), despite the lack of a significant difference in brachial systolic BP reduction between the 2 treatments...
  27. ncbi request reprint Relationship between morning hypertension identified by home blood pressure monitoring and brain natriuretic peptide and estimated glomerular filtration rate: the Japan Morning Surge 1 (JMS-1) Study
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 10:34-42. 2008
    ....
  28. pmc Ambulatory blood pressure is a better marker than clinic blood pressure in predicting cardiovascular events in patients with/without type 2 diabetes
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    Am J Hypertens 21:443-50. 2008
    ..The prognostic significance of ambulatory blood pressure (ABP) has not been established in patients with type 2 diabetes (T2DM)...
  29. doi request reprint Effect of dosing time of angiotensin II receptor blockade titrated by self-measured blood pressure recordings on cardiorenal protection in hypertensives: the Japan Morning Surge-Target Organ Protection (J-TOP) study
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    J Hypertens 28:1574-83. 2010
    ..To study the impact of the dosing time of an angiotensin II receptor blocker (ARB) titrated by self-measured home blood pressure (HBP) on cardiorenal damage in hypertensives...
  30. ncbi request reprint Changes in self-monitored pulse pressure correlate with improvements in B-type natriuretic Peptide and urinary albumin in treated hypertensive patients
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 20:1268-75. 2007
    ..We assessed the hypothesis that changes in PP during antihypertensive therapy correlate with changes in surrogate markers of target-organ damage...
  31. doi request reprint Association between aldosterone induced by antihypertensive medication and arterial stiffness reduction: the J-CORE study
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, 3311 1 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
    Atherosclerosis 215:184-8. 2011
    ..We aimed to investigate the association of the change in plasma aldosterone concentration (PAC) by antihypertensive medication with the change in aortic pulse wave velocity (aPWV)...
  32. ncbi request reprint Collagen metabolism in extracellular matrix may be involved in arterial stiffness in older hypertensive patients with left ventricular hypertrophy
    Joji Ishikawa
    Division of Cardiology, Jichi Medial School, Tochigi, Japan
    Hypertens Res 28:995-1001. 2005
    ..05). In conclusion, arterial stiffness in high-risk older hypertensive patients may involve ECM collagen metabolism...
  33. doi request reprint Change in high-sensitive cardiac troponin T on hypertensive treatment
    Satoshi Hoshide
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    Clin Exp Hypertens 35:40-4. 2013
    ..05), but such a reduction was not found in the LOS/HCTZ group in the upper half group of Hs-cTnT level at baseline. Amlodipine had a more beneficial effect than LOS/HCTZ in patients with high Hs-cTnT levels...
  34. doi request reprint Association between asleep blood pressure and brain natriuretic peptide during antihypertensive treatment: the Japan Morning Surge-Target Organ Protection (J-TOP) study
    Motohiro Shimizu
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 30:1015-21. 2012
    ..This study investigated the correlation of brain natriuretic peptide (BNP) to asleep BP during antihypertensive treatment...
  35. ncbi request reprint Diabetic brain damage in hypertension: role of renin-angiotensin system
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical School, Tochigi, Japan
    Hypertension 45:887-93. 2005
    ..In conclusion, brain damage is advanced in DHTs. ARB partly improved the impaired cerebral microvascular function in DHTs...
  36. doi request reprint Poor blood pressure and urinary albumin excretion responses to home blood pressure-based antihypertensive therapy in depressive hypertensive patients
    Tomoyuki Kabutoya
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 12:345-9. 2010
    ..4 vs 10.1 mg/gCr, P<.05). Depressive hypertensive patients required a larger number of antihypertensive drugs to control HBP, and showed a smaller reduction in UACR than nondepressive hypertensives...
  37. doi request reprint Urinary albumin excretion during angiotensin II receptor blockade: comparison of combination treatment with a diuretic or a calcium-channel blocker
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 24:466-73. 2011
    ....
  38. ncbi request reprint Effects of new calcium channel blocker, azelnidipine, and amlodipine on baroreflex sensitivity and ambulatory blood pressure
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY 10032, USA
    J Cardiovasc Pharmacol 49:394-400. 2007
    ..Clinical and awake BPs were similarly reduced by each drug therapy. In conclusion, BRS was increased by azelnidipine therapy, but not by amlodipine therapy. This differential effect may be important in cardiovascular risk reduction...
  39. doi request reprint Association of home and ambulatory blood pressure changes with changes in cardiovascular biomarkers during antihypertensive treatment
    Yuichirou Yano
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 25:306-12. 2012
    ..Our aim was to assess whether home blood pressure (HBP) and ambulatory BP monitoring measurement (ABPM), in addition to office BP (OBP) predict changes of cardiovascular biomarkers during antihypertensive treatment...
  40. doi request reprint Cardiovascular prognosis of sustained and white-coat hypertension in patients with type 2 diabetes mellitus
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan
    Blood Press Monit 13:15-20. 2008
    ....
  41. doi request reprint Determinants of negative white-coat effect in treated hypertensive patients: the Jichi Morning Hypertension Research (J-MORE) study
    Tomoyuki Kabutoya
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 22:35-40. 2009
    ..The negative white-coat effect (WCE), a phenomenon in which out-of-office blood pressure (BP) is higher than clinic BP, has not been well examined, unlike the WCE...
  42. ncbi request reprint Morning blood pressure surge and hypertensive cerebrovascular disease: role of the alpha adrenergic sympathetic nervous system
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical School, Tochigi, Japan
    Am J Hypertens 17:668-75. 2004
    ..The morning surge of blood pressure (BP) is associated with alpha-adrenergic activity. We studied the association between the alpha-adrenergic morning surge in BP and silent cerebrovascular disease in elderly patients with hypertension...
  43. doi request reprint Increased heart rate variability during sleep is a predictor for future cardiovascular events in patients with type 2 diabetes
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan
    Hypertens Res 33:737-42. 2010
    ..In conclusion, increased HR variability during sleep was a predictor for incident CVD in T2DM, but not in non-diabetics. Increased HR variability at night would reflect pathophysiological mechanism of T2DM...
  44. doi request reprint The effect of pulse rate and blood pressure dipping status on the risk of stroke and cardiovascular disease in Japanese hypertensive patients
    Tomoyuki Kabutoya
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    Am J Hypertens 23:749-55. 2010
    ..Background: There have been few reports on the relationship between variation in the diurnal pulse rate (PR) in relation to a nondipper blood pressure (BP) pattern and cardiovascular events in elderly hypertensives...
  45. doi request reprint Is very low dose hydrochlorothiazide combined with candesartan effective in uncontrolled hypertensive patients?
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, School of Medicine, 3311 1 Yakushiji, Shimotsuke, Tochigi, Japan
    Blood Press Monit 15:308-11. 2010
    ..It is controversial whether the combination of very low dose hydrochlorothiazide (HCTZ) and an angiotensin receptor blocker (ARB) is effective in lowering blood pressure (BP)...
  46. ncbi request reprint Metabolic syndrome less strongly associated with target organ damage than syndrome components in a healthy, working population
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health and Hypertension Program, Columbia University Medical Center, New York, NY 10032, USA
    J Clin Hypertens (Greenwich) 9:337-44. 2007
    ..The data suggest that physicians should evaluate blood pressure and high-density lipoprotein cholesterol as well as other cardiovascular risk factors without regard to whether a patient meets the criteria for the MS...
  47. doi request reprint Association of an abnormal blood glucose level and morning blood pressure surge in elderly subjects with hypertension
    Motohiro Shimizu
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Hypertens 22:611-6. 2009
    ..We previously reported that morning blood pressure (BP) surge (MBPS) was an independent risk factor for stroke. We evaluated the determinants of MBPS in hypertensive patients...
  48. ncbi request reprint Effect of a novel calcium channel blocker on abnormal nocturnal blood pressure in hypertensive patients
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 15:465-72. 2013
    ..2%±9.6%, P=.617). Cilnidipine partially, but significantly, restored abnormal nocturnal dipping status toward a normal dipping pattern in hypertensive patients. ..
  49. ncbi request reprint Nighttime home blood pressure and the risk of hypertensive target organ damage
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Center for Community and General Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi 329 0498, Japan
    Hypertension 60:921-8. 2012
    ..In conclusion, nighttime home BP is slightly different from (but comparable to) nighttime ambulatory BP. The addition of nighttime home BP to other BP measures improves the association of BP with hypertensive target organ damage...
  50. ncbi request reprint Comparison of the effects of cilnidipine and amlodipine on ambulatory blood pressure
    Satoshi Hoshide
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Hypertens Res 28:1003-8. 2005
    ..27, p<0.05). N-type calcium channel blockade by cilnidipine may not cause reflex tachycardia, and may be useful for hypertensive treatment...
  51. pmc Soluble tumor necrosis factor receptor 1 level is associated with left ventricular hypertrophy: the northern Manhattan study
    Yasuyoshi Takei
    Division of Cardiology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Am J Hypertens 22:763-9. 2009
    ..We sought to evaluate whether inflammatory markers were independently associated with LVH in a multiethnic population in northern Manhattan...
  52. ncbi request reprint Factors associated with baroreflex sensitivity: association with morning blood pressure
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, NY, USA
    Hypertens Res 30:723-8. 2007
    ..In conclusion, impaired BRS evaluated by the Valsalva method was associated with high morning BP level, independent of other confounders. Morning hypertension might be partly mediated by impaired BRS...
  53. ncbi request reprint Can ischemic stroke be caused by acute reduction of blood pressure in the acute phase of cardiovascular disease?
    Satoshi Hoshide
    Division of Cardiovascular Medicine, Jichi Medical University, School of Medicine, 3311 1 Yakushiji, Shimotsuke ku, Tochigi, Japan
    J Clin Hypertens (Greenwich) 10:195-200. 2008
    ..Thus, acute pulmonary edema and diabetes were the most important factors related to ischemic stroke during BP reduction in patients with marked elevations of BP regardless of the rapidity of BP lowering...
  54. ncbi request reprint Masked hypertension defined by home blood pressure monitoring is associated with impaired flow-mediated vasodilatation in patients with cardiovascular risk factors
    Tomoyuki Kabutoya
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 15:630-6. 2013
    ..7±6.7 vs 11.5±8.8 mm × s, P=.048). Home systolic BP and masked hypertension defined by home BP were associated with a decrease in FMD-AUC120...
  55. pmc Nocturnal nondipping of heart rate predicts cardiovascular events in hypertensive patients
    Kazuo Eguchi
    Department of Cardiology, International University of Health and Welfare Hospital, Nasushiobara, Japan
    J Hypertens 27:2265-70. 2009
    ..We performed this study to test the hypothesis that nocturnal nondipping of HR predicts the risk of incident CVD independent of nocturnal blood pressure dipping pattern...
  56. ncbi request reprint U-curve relationship between orthostatic blood pressure change and silent cerebrovascular disease in elderly hypertensives: orthostatic hypertension as a new cardiovascular risk factor
    Kazuomi Kario
    Department of Cardiology, Jichi Medical School, Kawachi, Tochigi, Japan
    J Am Coll Cardiol 40:133-41. 2002
    ..The study investigated the clinical significance and mechanism of orthostatic blood pressure (BP) dysregulation in elderly hypertensive patients...
  57. doi request reprint A home blood pressure monitor equipped with a graphic function facilitates faster blood pressure control than the conventional home blood pressure monitor
    Tomoyuki Kabutoya
    Department of Medicine, Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Clin Hypertens (Greenwich) 11:422-5. 2009
    ..3+/-15.4 vs 147.7+/-10.8 mm Hg; P<.05); its reduction was significantly larger in the former group (11.9 vs 5.6 mm Hg; P<.05). Using an HBP device with a graphic display could accelerate the achievement of BP control...
  58. doi request reprint Association between the morning-evening difference in home blood pressure and cardiac damage in untreated hypertensive patients
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    J Hypertens 27:712-20. 2009
    ..The present study investigated whether the morning-evening difference in self-measured blood pressure (BP) (MEdif) can be an independent determinant of cardiac damage in untreated hypertensive patients...
  59. pmc Association between diabetes mellitus and left ventricular hypertrophy in a multiethnic population
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Am J Cardiol 101:1787-91. 2008
    ..Presence of T2DM increased the risk of LV hypertrophy by about 1.5-fold, and it possibly interacted with central obesity...
  60. doi request reprint Reproducibility of ambulatory blood pressure in treated and untreated hypertensive patients
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 28:918-24. 2010
    ..We tested the reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reduction in hypertensive patients...
  61. doi request reprint A bedtime dose of ARB was better than a morning dose in improving baroreflex sensitivity and urinary albumin excretion--the J-TOP study
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Clin Exp Hypertens 34:488-92. 2012
    ..17, P = .26), but were significant in the bedtime-dose group (r = -0.29, P = .04). In conclusion, the improvement of BRS could be one of the mechanisms by which bedtime dosing of ARB confers renal protection...
  62. doi request reprint The time course of flow-mediated vasodilation and endothelial dysfunction in patients with a cardiovascular risk factor
    Tomoyuki Kabutoya
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Am Soc Hypertens 6:109-16. 2012
    ..10, P = .011), after adjustments were made for age, gender, and smoking and drinking status. FMD-AUC120 was associated with cardiovascular risk...
  63. ncbi request reprint Subclinical arterial damage in untreated masked hypertensive subjects detected by home blood pressure measurement
    Yoshio Matsui
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    Am J Hypertens 20:385-91. 2007
    ..The purpose of this study was to investigate the subclinical arterial damage in unmedicated subjects with MHT detected by home BP measurement...
  64. doi request reprint Plasma tissue inhibitor of matrix metalloproteinase-1 level is increased in normotensive non-dippers in association with impaired glucose metabolism
    Joji Ishikawa
    Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, 3311 1 Yakushiji, Shimotsuke 329 0498, Japan
    Hypertens Res 31:2045-51. 2008
    ..Hypertens Res 2008; 31: 2045-2051)...
  65. ncbi request reprint Masked hypertension in diabetes mellitus: a potential risk
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY 10032, USA
    J Clin Hypertens (Greenwich) 9:601-7. 2007
    ..Diabetic patients with MHT showed evidence of brain and kidney damage. Hence, out-of-office monitoring of BP may be indicated in diabetics whose BP is normal in the clinic...
  66. doi request reprint Short sleep duration is an independent predictor of stroke events in elderly hypertensive patients
    Kazuo Eguchi
    Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
    J Am Soc Hypertens 4:255-62. 2010
    ..52; P = 0.001). Shorter sleep duration was an independent risk for future incidence of stroke events in hypertensive patients, especially those with SCIs...
  67. pmc Impaired flow-mediated vasodilatation is associated with increased left ventricular mass in a multiethnic population. The Northern Manhattan Study
    Takuya Hasegawa
    Division of Cardiology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Hypertens 23:413-9. 2010
    ..We tested the hypothesis that impaired flow-mediated vasodilatation (FMD) is associated with increased LV mass in a population-based multiethnic cohort...
  68. pmc Increased low-grade inflammation and plasminogen-activator inhibitor-1 level in nondippers with sleep apnea syndrome
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    J Hypertens 26:1181-7. 2008
    ..We investigated neurohumoral activation and risk factors in relation to nocturnal blood pressure dipping pattern and sleep apnea syndrome...
  69. ncbi request reprint Relationship between the change in left ventricular hypertrophy and asleep blood pressure after sodium restriction and/or diuretic treatment
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Blood Press Monit 16:172-9. 2011
    ....
  70. ncbi request reprint Altered aortic properties in elderly orthostatic hypertension
    Satoshi Hoshide
    Department of Cardiology, Jichi Medical School, Tochigi, Japan
    Hypertens Res 28:15-9. 2005
    ..There was no significant difference in the PWV between the OHT and ONT groups. Orthostatic hypertension was affected by altered aortic properties and associated with augmented wave reflection of arterial pressure...
  71. doi request reprint Prediction of strokes versus cardiac events by ambulatory monitoring of blood pressure: results from an international database
    Thomas Pickering
    Division of General Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Blood Press Monit 12:397-9. 2007
    ..70-0.94, chi2=7.70, d.f.=1, P=0.006] but not of cardiac events. It should not be assumed that one summary measure of ambulatory blood pressure would be the best predictor of different clinical outcomes...
  72. ncbi request reprint Differential effects of a long-acting angiotensin converting enzyme inhibitor (temocapril) and a long-acting calcium antagonist (amlodipine) on ventricular ectopic beats in older hypertensive patients
    Kazuo Eguchi
    Department of Internal Medicine, Nishiarita Kyoritsu Hospital, Saga, Japan
    Hypertens Res 25:329-33. 2002
    ..These results indicate that amlodipine is effective at lowering BP in older hypertensives, although it may increase VEB, especially when given at a high dose...
  73. ncbi request reprint Validation of an oscillometric home blood pressure monitor in an end-stage renal disease population and the effect of arterial stiffness on its accuracy
    Aliza M Thompson
    Department of Medicine, Behavioral Cardiovascular Health and Hypertension Program and Division of Nephrology, Columbia University, New York, New York, USA
    Blood Press Monit 12:227-32. 2007
    ..The purpose of this study was to validate an oscillometric home blood pressure monitor in an end-stage renal disease population and to determine the effect of arterial stiffness on its accuracy...
  74. ncbi request reprint Reproducibility of arterial stiffness indices (pulse wave velocity and augmentation index) simultaneously assessed by automated pulse wave analysis and their associated risk factors in essential hypertensive patients
    Yoshio Matsui
    Department of Internal Medicine, Miwa Municipal Hospital, Kuga gun, Yamaguchi, Japan
    Hypertens Res 27:851-7. 2004
    ..Automated simultaneous measurement of these arterial stiffness indices may be useful for risk stratification of hypertensives...
  75. ncbi request reprint Low-grade inflammation is a risk factor for clinical stroke events in addition to silent cerebral infarcts in Japanese older hypertensives: the Jichi Medical School ABPM Study, wave 1
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Stroke 38:911-7. 2007
    ....
  76. ncbi request reprint Circadian variation of blood pressure and neurohumoral factors during the acute phase of stroke
    Kazuo Eguchi
    Department of Internal Medicine, Nishiarita Kyoritsu Hospital, Japan
    Clin Exp Hypertens 24:109-14. 2002
    ..In conclusion the abnormal patterns of circadian BP rhythm were frequently observed during the acute phase of stroke. The cause of this abnormality may result from the diminished circadian rhythms of neurohumoral factors...
  77. ncbi request reprint Nocturnal blood pressure elevation predicts progression of albuminuria in elderly people with type 2 diabetes
    Walter Palmas
    Department of Medicine, Columbia University, New York, NY, USA
    J Clin Hypertens (Greenwich) 10:12-20. 2008
    ..In conclusion, nocturnal BP rise on ambulatory monitoring is superior to office BP to predict worsening of albuminuria in elderly individuals with type 2 diabetes and adds to the information provided by 24-hour pulse pressure...
  78. ncbi request reprint Masked nocturnal hypertension and target organ damage in hypertensives with well-controlled self-measured home blood pressure
    Satoshi Hoshide
    Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Japan
    Hypertens Res 30:143-9. 2007
    ..We must rule out masked hypertension using self-measured home BP monitoring, and we might also need to rule out nocturnal masked hypertension using ambulatory BP monitoring...
  79. ncbi request reprint Usefulness of fasting blood glucose to predict vascular outcomes among individuals without diabetes mellitus (from the Northern Manhattan Study)
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, New York, NY, USA
    Am J Cardiol 100:1404-9. 2007
    ..The effects were more apparent for MI than for ischemic stroke; however, FBG was a strong predictor of ischemic stroke among African-American subjects...
  80. doi request reprint Cognitive dysfunction and physical disability are associated with mortality in extremely elderly patients
    Satoshi Hoshide
    Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, 3311 1 Yakushiji, Shimotsuke 329 0498, Japan
    Hypertens Res 31:1331-8. 2008
    ....
  81. doi request reprint Tom Pickering as a clinical scientist: masked hypertension
    Kazuo Eguchi
    Department of Medicine, Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
    Blood Press Monit 15:85-9. 2010
    ..The biggest theme in the field of hypertension is how we can detect masked hypertension. I present two interesting cases of possible masked hypertension in this commentary...
  82. ncbi request reprint [Papillary fibroelastoma in the right ventricular outflow tract: a case report]
    Hidenori Tomizawa
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Yakushiji, Shimotsuke, Tochigi
    J Cardiol 49:199-203. 2007
    ..Histological examination confirmed papillary fibroelastoma. The predominant location of papillary fibroelastoma is the valvular surface. This very rare case of papillary fibroelastoma was located in the right ventricular outflow tract...
  83. ncbi request reprint Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Hypertens Res 30:23-30. 2007
    ..Early intervention with pioglitazone or metformin therapy may reduce the incidence of future cardiovascular disease in subjects with impaired glucose tolerance or early diabetes...
  84. ncbi request reprint Morning hypertension: the strongest independent risk factor for stroke in elderly hypertensive patients
    Kazuomi Kario
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan
    Hypertens Res 29:581-7. 2006
    ....
  85. pmc What is the optimal interval between successive home blood pressure readings using an automated oscillometric device?
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan
    J Hypertens 27:1172-7. 2009
    ..To clarify whether a shorter interval between three successive home blood pressure (HBP) readings (10 s vs. 1 min) taken twice a day gives a better prediction of the average 24-h BP and better patient compliance...
  86. ncbi request reprint Differential impact of left ventricular mass and relative wall thickness on cardiovascular prognosis in diabetic and nondiabetic hypertensive subjects
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tokyo, Japan
    Am Heart J 154:79.e9-15. 2007
    ..Cardiovascular prognostic significance of relative wall thickness (RWT) in patients with diabetes has not been reported although concentric hypertrophy is common in diabetic patients...
  87. ncbi request reprint [What is a good marker for better antihypertensive therapy in diabetic patients when coexisting with hypertension]
    Kazuo Eguchi
    Department of Internal Medicine, Nishiarita Kyoritsu Hospital
    Nihon Rinsho 60:679-84. 2002
  88. ncbi request reprint Consistency of blood pressure differences between the left and right arms
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical College, New York, USA
    Arch Intern Med 167:388-93. 2007
    ..It is unclear to what extent interarm blood pressure (BP) differences are reproducible vs the result of random error. The present study was designed to resolve this issue...
  89. ncbi request reprint Two cases of malignant hypertension with reversible diffuse leukoencephalopathy exhibiting a reversible nocturnal blood pressure "riser" pattern
    Kazuo Eguchi
    Department of Internal Medicine, Nishiarita Kyoritsu Hospital, Saga, Japan
    Hypertens Res 25:467-73. 2002
    ..In conclusion, a possible explanation of this phenomenon is that a causative volume overload due to renal dysfunction produced the temporal leukoencephalopathy-like brain edema and "riser" pattern in these cases...
  90. doi request reprint Determinants of self-measured pulse rate profile in medicated hypertensives: the Jichi Morning Surge-1 (JMS-1) study
    Tomoyuki Kabutoya
    Chichibu Municipal Hospital, Saitama, Japan
    Clin Exp Hypertens 30:255-65. 2008
    ..However, the predictor of high PR at home in treated hypertensives is unknown. In this study, we studied the predictor of high PR and evaluated pulse rate variability (PRV)...
  91. doi request reprint Factors associated with incident ischemic stroke in hospitalized heart failure patients: a pilot study
    Takahiro Komori
    Department of Cardiovascular Medicine, Utsunomiya Social Insurance Hospital, Utsunomiya, Japan
    Hypertens Res 31:289-94. 2008
    ..In this pilot study, elevated nocturnal BP and high plasma BNP just before patients left the hospital were significant predictors of stroke events in CHF patients. Further study is needed to confirm this hypothesis...
  92. doi request reprint The influence of wave reflection on left ventricular hypertrophy in hypertensive patients is modified by age and gender
    Yoshio Matsui
    Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan
    Hypertens Res 31:649-56. 2008
    ..The lack of any such association in older hypertensives can be explained by both the plateau in the values of carotid AIx, and the fact that LVM increased with age...
  93. ncbi request reprint [Diagnostic criteria for white-coat hypertension]
    Kazuo Eguchi
    Nihon Naika Gakkai Zasshi 92:202-7. 2003
  94. ncbi request reprint The morning-evening difference in self-measured blood pressure: a potential predictor of cardiovascular disease
    Kazuo Eguchi
    Hypertens Res 30:877-8. 2007
  95. ncbi request reprint Differential impacts of adiponectin on low-grade albuminuria between obese and nonobese persons without diabetes
    Yuichiro Yano
    From the Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan
    J Clin Hypertens (Greenwich) 9:775-82. 2007
    ..20 vs 5.11 microg/min; P<.05), even after adjustment for age, sex, blood pressure level, and glucose level. There was an inverse association between adiponectin and low-grade albuminuria in obese nondiabetic persons...
  96. ncbi request reprint The Japan Morning Surge-1 (JMS-1) study: protocol description
    Joji Ishikawa
    Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Japan
    Hypertens Res 29:153-9. 2006
    ....
  97. ncbi request reprint [Smoking and hypertension]
    Kazuo Eguchi
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine
    Nihon Rinsho 64:242-6. 2006
  98. ncbi request reprint Regular alcohol drinking is a determinant of masked morning hypertension detected by home blood pressure monitoring in medicated hypertensive patients with well-controlled clinic blood pressure: the Jichi Morning Hypertension Research (J-MORE) study
    Joji Ishikawa
    Division of Cardiovascular Medicine, Department of Medicine, Jichi Medial University School of Medicine, Shimotsuke, Japan
    Hypertens Res 29:679-86. 2006
    ..01). In conclusion, regular alcohol drinking is an independent determinant for MMHT detected by home BP monitoring in medicated hypertensive patients with well-controlled clinic BP...
  99. ncbi request reprint Masked hypertension: a review
    Thomas G Pickering
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, New York 10032, USA
    Hypertens Res 30:479-88. 2007
    ..The potential implications of masked hypertension are huge, but the optimal strategy for detecting the condition in the general population is not yet clear...
  100. ncbi request reprint Why is blood pressure so hard to control in patients with type 2 diabetes?
    Kazuo Eguchi
    Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, New York, NY 10032, USA
    J Cardiometab Syndr 2:114-8. 2007
    ....
  101. ncbi request reprint [Beneficial effect of ARB for ischemic stroke]
    Kazuo Eguchi
    Department of Internal Medicine, Nishiarita Kyoritsu Hospital
    Nihon Rinsho 60:1987-91. 2002
    ..This trial is expected to clarify whether early treatment with candesartan during the acute stage of stroke is beneficial for the neurological outcome or prognosis...