Yutaka Nakashima

Summary

Affiliation: Japanese Red Cross
Country: Japan

Publications

  1. doi request reprint Risk factors for coronary atherosclerosis in a general Japanese population: the Hisayama study
    Yutaka Nakashima
    Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pathol Res Pract 205:700-8. 2009
  2. doi request reprint Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans
    Yutaka Nakashima
    Division of Pathology, Fukuoka Red Cross Hospital, 3 1 1 Ogusu, Fukuoka 815 8555, Japan
    Cardiovasc Res 79:14-23. 2008
  3. ncbi request reprint Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration
    Yutaka Nakashima
    Graduate School of Medical Sciences, Kyushu University, Japan
    Arterioscler Thromb Vasc Biol 27:1159-65. 2007
  4. doi request reprint Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study
    Jingyu Song
    Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Atherosclerosis 202:573-81. 2009
  5. ncbi request reprint Immunohistochemical alpha- and beta-catenin and E-cadherin expression and their clinicopathological significance in human lung adenocarcinoma
    Nobuyoshi Nozawa
    Department of Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Pathol Res Pract 202:639-50. 2006
  6. ncbi request reprint Interleukin-10 expression is positively correlated with oxidized LDL deposition and inversely with T-lymphocyte infiltration in atherosclerotic intimas of human coronary arteries
    Shinji Sumiyoshi
    Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pathol Res Pract 202:141-50. 2006
  7. ncbi request reprint Angiogenesis and lymphangiogenesis and expression of lymphangiogenic factors in the atherosclerotic intima of human coronary arteries
    Toshiaki Nakano
    Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 36:330-40. 2005
  8. doi request reprint Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study
    Toshiaki Nakano
    1 Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2 Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Kidney Int 84:373-80. 2013
  9. ncbi request reprint [Pathological characteristics of diabetic macro-angiopathy]
    Katsuo Sueishi
    Division of Pathophysiology and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University
    Nihon Rinsho 64:2005-11. 2006
  10. ncbi request reprint Immune and non-immune factors in cryopreserved tissues
    Yukihiro Tomita
    Department of Cardiovascular Surgery, Faculty of Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    J Heart Lung Transplant 22:560-7. 2003

Collaborators

Detail Information

Publications17

  1. doi request reprint Risk factors for coronary atherosclerosis in a general Japanese population: the Hisayama study
    Yutaka Nakashima
    Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pathol Res Pract 205:700-8. 2009
    ....
  2. doi request reprint Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans
    Yutaka Nakashima
    Division of Pathology, Fukuoka Red Cross Hospital, 3 1 1 Ogusu, Fukuoka 815 8555, Japan
    Cardiovasc Res 79:14-23. 2008
    ....
  3. ncbi request reprint Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration
    Yutaka Nakashima
    Graduate School of Medical Sciences, Kyushu University, Japan
    Arterioscler Thromb Vasc Biol 27:1159-65. 2007
    ..The present study was designed to clarify the morphological features of early human atherosclerosis and to determine whether specific extracellular matrix proteoglycans play a role in early atherogenesis...
  4. doi request reprint Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama study
    Jingyu Song
    Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Atherosclerosis 202:573-81. 2009
    ..The association of HO-1 overexpression with a greater extent of intraplaque angiogenesis suggests a multi-faceted role for HO-1 in modulating the progression of atherosclerosis...
  5. ncbi request reprint Immunohistochemical alpha- and beta-catenin and E-cadherin expression and their clinicopathological significance in human lung adenocarcinoma
    Nobuyoshi Nozawa
    Department of Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Pathol Res Pract 202:639-50. 2006
    ..Moreover, the immunohistochemical expression of beta-catenin by cancer cells and MIB-1 index are considered useful prognostic factors for lung adenocarcinoma...
  6. ncbi request reprint Interleukin-10 expression is positively correlated with oxidized LDL deposition and inversely with T-lymphocyte infiltration in atherosclerotic intimas of human coronary arteries
    Shinji Sumiyoshi
    Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Pathol Res Pract 202:141-50. 2006
    ..01). These findings suggest that IL-10 expression, seen mainly in macrophages, was possibly upregulated with oxLDL, and was inversely correlated with T-lymphocytic function in atherosclerotic coronary intimas...
  7. ncbi request reprint Angiogenesis and lymphangiogenesis and expression of lymphangiogenic factors in the atherosclerotic intima of human coronary arteries
    Toshiaki Nakano
    Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Hum Pathol 36:330-40. 2005
    ..Imbalance of angiogenesis and lymphangiogenesis may be a factor contributing to sustained inflammatory reaction during human coronary atherogenesis...
  8. doi request reprint Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study
    Toshiaki Nakano
    1 Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2 Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Kidney Int 84:373-80. 2013
    ..73 m(2). Thus, elderly patients with CKD have intimal neoangiogenesis and an increased risk of intraplaque hemorrhage in coronary arteries, possibly favored by local accumulation of oxLDL and VEGF. ..
  9. ncbi request reprint [Pathological characteristics of diabetic macro-angiopathy]
    Katsuo Sueishi
    Division of Pathophysiology and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University
    Nihon Rinsho 64:2005-11. 2006
    ....
  10. ncbi request reprint Immune and non-immune factors in cryopreserved tissues
    Yukihiro Tomita
    Department of Cardiovascular Surgery, Faculty of Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    J Heart Lung Transplant 22:560-7. 2003
    ..Although cryopreserved tissues are used clinically, the effects of cryopreservation on antigenicity leading to immune and non-immune responses are not well known...
  11. ncbi request reprint Clinicopathologic relevance of apoptotic and proliferative factors in human lung adenocarcinoma: Fas expression correlates with the histologic subtype, but not with the degree of apoptosis
    Sepideh Mojtahedzadeh
    Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Pathol Res Pract 198:645-54. 2002
    ..Based on these data, intracytoplasmic expression of Fas in cancer cells may participate in the development of resistance to fas-mediated apoptosis...
  12. ncbi request reprint Distributions of diffuse intimal thickening in human arteries: preferential expression in atherosclerosis-prone arteries from an early age
    Yutaka Nakashima
    Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Virchows Arch 441:279-88. 2002
    ..Thus, DIT was strongly expressed from an early age in arteries that are considered to be prone to atherosclerosis. These findings suggest that the development of atherosclerosis depends at least partly on the degree of DIT...
  13. doi request reprint Objective response with lapatinib in patients with meningitis carcinomatosa derived from HER2/HER1-negative breast cancer
    Hideya Onishi
    Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Int J Clin Oncol 16:718-21. 2011
    ..Here, we report the first case in which lapatinib has been used to effectively treat meningitis carcinomatosa in HER2(-)/HER1(-) relapsed breast cancer...
  14. ncbi request reprint A case of lymphangioleiomyomatosis affecting the supraclavicular lymph nodes
    Takeshi Kamitani
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Comput Assist Tomogr 30:279-82. 2006
    ..The common sites of extrapulmonary LAM include retroperitoneal and mediastinal lymph nodes; however, supraclavicular lymph node involvement is extremely rare...
  15. doi request reprint Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitis
    Junji Umeno
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Gastrointest Endosc 67:1185-91. 2008
    ..Although some cases of collagenous colitis have been induced by lansoprazole (LPZ), the clinicopathologic features of LPZ-associated collagenous colitis have not been elucidated...
  16. ncbi request reprint A decrease in AFP level related to administration of interferon in patients with chronic hepatitis C and a high level of AFP
    Shiro Murashima
    Department of Internal Medicine, Kurume Medical Center, Kurume, Fukuoka, Japan
    Dig Dis Sci 51:808-12. 2006
    ..Since AFP is a significant predictor for HCC, therapeutic strategies for hepatitis C, e.g., long-term low-dose IFN treatment, may reduce hepatocarcinogenesis...
  17. ncbi request reprint Plaque-stabilizing effect of pitavastatin in Watanabe heritable hyperlipidemic (WHHL) rabbits
    Hideo Suzuki
    Tokyo New Drug Research Laboratories I, Pharmaceutical Division, Kowa Co Ltd, 2 17 43 Noguchi cho, Higashi murayama, Tokyo 189 0022, Japan
    J Atheroscler Thromb 10:109-16. 2003
    ..1, 40.6 and 52.3%, respectively. These results indicated that pitavastatin had an excellent lipid-lowering effect in WHHL rabbits, suppressing the progression of atherosclerosis and stabilizing atherosclerotic plaque...