Research Topics
| Yutaka NakashimaSummaryAffiliation: Japanese Red Cross Country: Japan Publications
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Detail Information
Publications
Risk factors for coronary atherosclerosis in a general Japanese population: the Hisayama studyYutaka Nakashima
Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Pathol Res Pract 205:700-8. 2009....
Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycansYutaka Nakashima
Division of Pathology, Fukuoka Red Cross Hospital, 3 1 1 Ogusu, Fukuoka 815 8555, Japan
Cardiovasc Res 79:14-23. 2008....
Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltrationYutaka Nakashima
Graduate School of Medical Sciences, Kyushu University, Japan
Arterioscler Thromb Vasc Biol 27:1159-65. 2007..The present study was designed to clarify the morphological features of early human atherosclerosis and to determine whether specific extracellular matrix proteoglycans play a role in early atherogenesis...
Overexpression of heme oxygenase-1 in coronary atherosclerosis of Japanese autopsies with diabetes mellitus: Hisayama studyJingyu Song
Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Atherosclerosis 202:573-81. 2009..The association of HO-1 overexpression with a greater extent of intraplaque angiogenesis suggests a multi-faceted role for HO-1 in modulating the progression of atherosclerosis...
Immunohistochemical alpha- and beta-catenin and E-cadherin expression and their clinicopathological significance in human lung adenocarcinomaNobuyoshi Nozawa
Department of Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
Pathol Res Pract 202:639-50. 2006..Moreover, the immunohistochemical expression of beta-catenin by cancer cells and MIB-1 index are considered useful prognostic factors for lung adenocarcinoma...
Interleukin-10 expression is positively correlated with oxidized LDL deposition and inversely with T-lymphocyte infiltration in atherosclerotic intimas of human coronary arteriesShinji Sumiyoshi
Department of Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Pathol Res Pract 202:141-50. 2006..01). These findings suggest that IL-10 expression, seen mainly in macrophages, was possibly upregulated with oxLDL, and was inversely correlated with T-lymphocytic function in atherosclerotic coronary intimas...
Angiogenesis and lymphangiogenesis and expression of lymphangiogenic factors in the atherosclerotic intima of human coronary arteriesToshiaki Nakano
Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
Hum Pathol 36:330-40. 2005..Imbalance of angiogenesis and lymphangiogenesis may be a factor contributing to sustained inflammatory reaction during human coronary atherogenesis...
[Pathological characteristics of diabetic macro-angiopathy]Katsuo Sueishi
Division of Pathophysiology and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University
Nippon Rinsho 64:2005-11. 2006....
Distributions of diffuse intimal thickening in human arteries: preferential expression in atherosclerosis-prone arteries from an early ageYutaka Nakashima
Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Virchows Arch 441:279-88. 2002..Thus, DIT was strongly expressed from an early age in arteries that are considered to be prone to atherosclerosis. These findings suggest that the development of atherosclerosis depends at least partly on the degree of DIT...
Immune and non-immune factors in cryopreserved tissuesYukihiro Tomita
Department of Cardiovascular Surgery, Faculty of Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
J Heart Lung Transplant 22:560-7. 2003..Although cryopreserved tissues are used clinically, the effects of cryopreservation on antigenicity leading to immune and non-immune responses are not well known...
Clinicopathologic relevance of apoptotic and proliferative factors in human lung adenocarcinoma: Fas expression correlates with the histologic subtype, but not with the degree of apoptosisSepideh Mojtahedzadeh
Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Pathol Res Pract 198:645-54. 2002..Based on these data, intracytoplasmic expression of Fas in cancer cells may participate in the development of resistance to fas-mediated apoptosis...
Objective response with lapatinib in patients with meningitis carcinomatosa derived from HER2/HER1-negative breast cancerHideya Onishi
Department of Cancer Therapy and Research, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
Int J Clin Oncol 16:718-21. 2011..Here, we report the first case in which lapatinib has been used to effectively treat meningitis carcinomatosa in HER2(-)/HER1(-) relapsed breast cancer...
A case of lymphangioleiomyomatosis affecting the supraclavicular lymph nodesTakeshi Kamitani
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Comput Assist Tomogr 30:279-82. 2006..The common sites of extrapulmonary LAM include retroperitoneal and mediastinal lymph nodes; however, supraclavicular lymph node involvement is extremely rare...
Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitisJunji Umeno
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gastrointest Endosc 67:1185-91. 2008..Although some cases of collagenous colitis have been induced by lansoprazole (LPZ), the clinicopathologic features of LPZ-associated collagenous colitis have not been elucidated...
A decrease in AFP level related to administration of interferon in patients with chronic hepatitis C and a high level of AFPShiro Murashima
Department of Internal Medicine, Kurume Medical Center, Kurume, Fukuoka, Japan
Dig Dis Sci 51:808-12. 2006..Since AFP is a significant predictor for HCC, therapeutic strategies for hepatitis C, e.g., long-term low-dose IFN treatment, may reduce hepatocarcinogenesis...
Plaque-stabilizing effect of pitavastatin in Watanabe heritable hyperlipidemic (WHHL) rabbitsHideo Suzuki
Tokyo New Drug Research Laboratories I, Pharmaceutical Division, Kowa Co Ltd, 2 17 43 Noguchi cho, Higashi murayama, Tokyo 189 0022, Japan
J Atheroscler Thromb 10:109-16. 2003..1, 40.6 and 52.3%, respectively. These results indicated that pitavastatin had an excellent lipid-lowering effect in WHHL rabbits, suppressing the progression of atherosclerosis and stabilizing atherosclerotic plaque...
