Masayuki Kurosaki

Summary

Affiliation: Japanese Red Cross
Country: Japan

Publications

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
  2. doi request reprint Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino, Tokyo 180 8610, Japan
    J Gastroenterol 46:401-9. 2011
  3. doi request reprint Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Antivir Ther 17:35-43. 2012
  4. doi request reprint Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Hepatology 55:20-9. 2012
  5. doi request reprint Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Gastroenterology 134:1396-405. 2008
  6. ncbi request reprint Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C
    Yasuhiro Asahina
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino shi, Tokyo 180 8610, Japan
    J Hepatol 43:623-9. 2005
  7. doi request reprint Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Hepatol 56:602-8. 2012
  8. doi request reprint Sequences in the interferon sensitivity-determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG-interferon plus ribavirin: data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Med Virol 83:445-52. 2011
  9. doi request reprint Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Hepatology 52:518-27. 2010
  10. doi request reprint Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C
    Masayuki Kurosaki
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Med Virol 85:449-58. 2013

Collaborators

Detail Information

Publications31

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
    ....
  2. doi request reprint Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino, Tokyo 180 8610, Japan
    J Gastroenterol 46:401-9. 2011
    ..This study aimed to develop a model for the pre-treatment prediction of sustained virological response (SVR) to peg-interferon plus ribavirin therapy in chronic hepatitis C...
  3. doi request reprint Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Antivir Ther 17:35-43. 2012
    ..This study aimed to define factors associated with relapse among responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in chronic hepatitis C...
  4. doi request reprint Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Hepatology 55:20-9. 2012
    ..IPS-1 down-regulation in IL28B minor patients was confirmed by western blotting, and the extent of IPS-1 protein cleavage was associated with the variable treatment response...
  5. doi request reprint Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Gastroenterology 134:1396-405. 2008
    ..The aim is to elucidate the mechanisms underlying resistance to antiviral therapy and predictive usefulness of gene quantification in chronic hepatitis C (CH-C)...
  6. ncbi request reprint Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C
    Yasuhiro Asahina
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino shi, Tokyo 180 8610, Japan
    J Hepatol 43:623-9. 2005
    ..To elucidate whether ribavirin acts as a mutagen in the clinical setting and to clarify the relationship between ribavirin-induced mutations and virological response to combined therapy...
  7. doi request reprint Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Hepatol 56:602-8. 2012
    ..We aimed to build a simple model for the identification of patients at high risk of developing HCC...
  8. doi request reprint Sequences in the interferon sensitivity-determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG-interferon plus ribavirin: data mining analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Med Virol 83:445-52. 2011
    ..A decision-tree model that includes these viral factors as predictors could identify patients with a high probability of sustained virological response...
  9. doi request reprint Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Hepatology 52:518-27. 2010
    ..Hepatitis C viral eradication had a smaller effect on hepatocarcinogenesis in older patients. Patients should therefore be identified at an earlier age and treatment should be initiated...
  10. doi request reprint Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C
    Masayuki Kurosaki
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Med Virol 85:449-58. 2013
    ..In conclusion, a predictive model incorporating the ITPA genotype could identify patients with a high risk of anemia and reduced probability of sustained virological response...
  11. ncbi request reprint Development of hepatocellular carcinoma after interferon therapy in chronic hepatitis C. Is it possible to reduce the incidence by ribanirin and IFN combination therapy?
    Namiki Izumi
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Intervirology 48:59-63. 2005
    ..The aim of this study is to investigate the risk factors for the development of HCC after IFN in chronic hepatitis C as well as whether the incidence of HCC will be reduced by ribavirin and IFN combination therapy or not...
  12. doi request reprint Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Antivir Ther 16:685-94. 2011
    ..The aim of this study was to replicate this finding in an independent Japanese cohort and to define a method to allow pretreatment prediction of anaemia in combination with other factors...
  13. doi request reprint Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Musashino shi, Tokyo, Japan
    J Hepatol 54:439-48. 2011
    ..Recent studies revealed an association between the IL28B genotype and treatment response. We aimed to develop a model for the pre-treatment prediction of response using host and viral factors...
  14. ncbi request reprint [A case of systemic amyloidosis with cholangiectasis diagnosed by liver biopsy]
    Yuji Kawano
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Japan
    Nihon Shokakibyo Gakkai Zasshi 110:1030-7. 2013
    ..Oral administration of melphalan and dexamethasone improved his clinical features and CT findings. We consider this case as rare in that the deposition of amyloid protein caused cholangiectasis...
  15. doi request reprint α-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C
    Yasuhiro Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan Department of Liver Disease Control, Tokyo Medical and Dental University, Tokyo, Japan
    Hepatology 58:1253-62. 2013
    ..Measurement of these values is useful for predicting future HCC risk after IFN treatment. Suppression of these values after IFN therapy reduces HCC risk even in patients without HCV eradication...
  16. ncbi request reprint Polymerase domain B mutation is associated with hepatitis relapse during long-term lamivudine therapy for chronic hepatitis B
    Hiroyuki Nakanishi
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Intervirology 48:381-8. 2005
    ..In conclusion, genotypic assays for the rt180M mutation after viral breakthrough may be useful in predicting the risk of breakthrough hepatitis and in deciding when to initiate alternative or additive nucleoside analogue therapy...
  17. doi request reprint Early decrease in α-fetoprotein, but not des-γ-carboxy prothrombin, predicts sorafenib efficacy in patients with advanced hepatocellular carcinoma
    Teiji Kuzuya
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Musashino, Tokyo, Japan
    Oncology 81:251-8. 2011
    ....
  18. doi request reprint Changes in hepatitis C viral load during first 14 days can predict the undetectable time point of serum viral load by pegylated interferon and ribavirin therapy
    Jun Itakura
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan Abbott Molecular, Des Plaines, Illinois, USA
    Hepatol Res 41:217-24. 2011
    ..An early response reflects sensitivity to therapy, and the estimation of an undetectable time point would be useful for determining the optimal duration of treatment for chronic hepatitis C patients...
  19. doi request reprint Expression of keratin 19 is related to high recurrence of hepatocellular carcinoma after radiofrequency ablation
    Kaoru Tsuchiya
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Oncology 80:278-88. 2011
    ..We investigated the clinical usefulness of K19 positivity in patients who had received curative radiofrequency ablation (RFA)...
  20. doi request reprint Changes in plasma vascular endothelial growth factor at 8 weeks after sorafenib administration as predictors of survival for advanced hepatocellular carcinoma
    Kaoru Tsuchiya
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Cancer 120:229-37. 2014
    ..In the current study, the authors examined changes in plasma VEGF concentrations during sorafenib treatment and determined the clinical significance of VEGF as a prognostic indicator in patients with HCC...
  21. ncbi request reprint A predictive model of response to peginterferon ribavirin in chronic hepatitis C using classification and regression tree analysis
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino shi, Tokyo 180 8610, Japan
    Hepatol Res 40:251-60. 2010
    ....
  22. pmc Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study
    Namiki Izumi
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Musashino, Japan
    J Gastroenterol 48:382-90. 2013
    ..We investigated whether the administration of maintenance doses of interferon prevented hepatocellular carcinoma (HCC) in patients with chronic hepatitis C...
  23. ncbi request reprint Repeated radiofrequency ablation for the distant recurrence in the liver in patients with chronic hepatitis C virus infection achieving long-term survival
    Namiki Izumi
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Musashinoshi, Tokyo, Japan
    Hepatol Res 37:S254-63. 2007
    ..It is a point of controversy when liver transplantation should be recommended in HCC patients with liver cirrhosis of Child-Pugh A classification having chronic HCV infection because of the high incidence of recurrence...
  24. pmc Hyperglycemia is a significant prognostic factor of hepatocellular carcinoma after curative therapy
    Takanori Hosokawa
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo 180 8610, Japan
    World J Gastroenterol 19:249-57. 2013
    ..To evaluate whether metabolic factors are related to distant recurrence of hepatocellular carcinoma (HCC) and survival after curative treatment...
  25. ncbi request reprint Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha
    Yoko Tanabe
    Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan
    J Infect Dis 189:1129-39. 2004
    ..Our results suggest that the direct effects of ribavirin on the genetic stability of the HCV subgenome and its synergistic action combined, with IFN-alpha, may explain the improved clinical responses to combination therapy...
  26. doi request reprint The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino shi, Tokyo, Japan
    J Hepatol 48:736-42. 2008
    ..The aim of the present study was to define factors associated with progression of fibrosis in patients who do not achieve a SVR...
  27. doi request reprint Reproducibility and usability of chronic virus infection model using agent-based simulation; comparing with a mathematical model
    Jun Itakura
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, 1 26 1 Kyonan cho, Musashino shi, Tokyo 180 8610, Japan
    Biosystems 99:70-8. 2010
    ..These agent-based simulation models reproducibly provide a visual representation of the disease, and enable a simulation that encompasses parameters those are difficult to account for in a mathematical model...
  28. ncbi request reprint A comparison of the exponential decay slope between PEG-IFN alfa-2b/ribavirin and IFN alfa-2b/ribavirin combination therapy in patients with chronic hepatitis C genotype 1b infection and a high viral load
    Namiki Izumi
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Intervirology 47:102-7. 2004
    ..Viral dynamics have been utilized for the evaluation of antiviral effects, especially the exponential second decay slope, which represents the elimination of infected cells...
  29. ncbi request reprint [Analysis of replicating hepatitis C virus quasispecies in hepatocellular carcinoma tissues]
    Masayuki Kurosaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital
    Nihon Rinsho 62:624-8. 2004
  30. pmc Predictors of virological response to a combination therapy with pegylated interferon plus ribavirin including virus and host factors
    Namiki Izumi
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Kyonancho 1 26 1, Musashinoshi, 180 8610 Tokyo, Japan
    Hepat Res Treat 2010:703602. 2010
    ..Since new anti-HCV agents are under development, it will be necessary in the future to select the patients who have a high possibility of achieving SVR if treatment is performed with standard regimen...
  31. ncbi request reprint Hepatitis C virus nonstructural protein 5A inhibits tumor necrosis factor-alpha-mediated apoptosis in Huh7 cells
    Yuka Miyasaka
    Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan
    J Infect Dis 188:1537-44. 2003
    ..These findings suggest that the NS5A protein inhibits the apoptotic effect of TNF-alpha upstream of caspase-8 in the apoptosis cascade...