Masaaki Seki

Summary

Affiliation: Japan BCG Central Laboratory
Country: Japan

Publications

  1. doi request reprint The effect of passages during Japanese BCG vaccine production on genetic stability and protective efficacy
    Masaaki Seki
    Japan BCG Laboratory, Japan
    Vaccine 30:1460-4. 2012
  2. doi request reprint Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guérin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains
    Masaaki Seki
    Japan BCG Laboratory, Research of Product, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 27:1710-6. 2009
  3. ncbi request reprint Modified multiplex PCR for identification of Bacillus Calmette-Guérin substrain Tokyo among clinical isolates
    Masaaki Seki
    Japan BCG Laboratory, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 23:3099-102. 2005
  4. ncbi request reprint Identification of two subpopulations of Bacillus Calmette-Guérin (BCG) Tokyo172 substrain with different RD16 regions
    Ikuro Honda
    Central Laboratory, Japan BCG Laboratory, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 24:4969-74. 2006
  5. ncbi request reprint Epididymo-orchitis caused by intravesically instillated bacillus Calmette-Guérin: genetically proven using a multiplex polymerase chain reaction method
    Hiroshi Harada
    Department of Urology, Sapporo City General Hospital, Sapporo, Japan
    Int J Urol 13:183-5. 2006
  6. pmc Multiplex PCR-identified cutaneous tuberculosis evoked by Mycobacterium bovis BCG vaccination in a healthy baby
    Tatsuma Okazaki
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    J Clin Microbiol 43:523-5. 2005
  7. ncbi request reprint [Surgical site infection by bacillus Calmette-Guerin (BCG) after radical cystectomy, occurring after intravesical bcg therapy: a case report]
    Takashi Muranaka
    Department of Urology, Sapporo Medical University
    Hinyokika Kiyo 53:581-4. 2007
  8. doi request reprint Report of an international collaborative study to establish the suitability of using modified ATP assay for viable count of BCG vaccine
    Mei M Ho
    Bacteriology Division, NIBSC, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Vaccine 26:4754-7. 2008
  9. ncbi request reprint Quantitative analyses of mRNA and protein levels of neurotrophin-3 in the rat retina during postnatal development and aging
    Masaaki Seki
    Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951 8585, Japan
    Jpn J Ophthalmol 48:460-4. 2004
  10. ncbi request reprint BDNF is upregulated by postnatal development and visual experience: quantitative and immunohistochemical analyses of BDNF in the rat retina
    Masaaki Seki
    Department of Molecular Neurobiology, Brain Research Institute, and Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Invest Ophthalmol Vis Sci 44:3211-8. 2003

Collaborators

Detail Information

Publications10

  1. doi request reprint The effect of passages during Japanese BCG vaccine production on genetic stability and protective efficacy
    Masaaki Seki
    Japan BCG Laboratory, Japan
    Vaccine 30:1460-4. 2012
    ....
  2. doi request reprint Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guérin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains
    Masaaki Seki
    Japan BCG Laboratory, Research of Product, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 27:1710-6. 2009
    ..These findings are useful for better understanding of the genetic differences in BCG substrains due to in vitro evolution of BCG...
  3. ncbi request reprint Modified multiplex PCR for identification of Bacillus Calmette-Guérin substrain Tokyo among clinical isolates
    Masaaki Seki
    Japan BCG Laboratory, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 23:3099-102. 2005
    ..Our method clearly identified BCG substrain (BCG Tokyo 172) among clinical isolates and easily distinguished between M. tuberculosis and wild-type Mycobacterium bovis...
  4. ncbi request reprint Identification of two subpopulations of Bacillus Calmette-Guérin (BCG) Tokyo172 substrain with different RD16 regions
    Ikuro Honda
    Central Laboratory, Japan BCG Laboratory, 3 1 5 Matsuyama, Kiyose City, Tokyo 204 0022, Japan
    Vaccine 24:4969-74. 2006
    ..It was suggested that types I and II constituted independent subpopulations within the Tokyo172 substrain. Type I was shown to have a growth advantage over type II both on culture media and in mice organs...
  5. ncbi request reprint Epididymo-orchitis caused by intravesically instillated bacillus Calmette-Guérin: genetically proven using a multiplex polymerase chain reaction method
    Hiroshi Harada
    Department of Urology, Sapporo City General Hospital, Sapporo, Japan
    Int J Urol 13:183-5. 2006
    ..Our report illustrates the efficacy of this method to detect the responsible microbe that is thought to be transmitted from the instillated BCG strain...
  6. pmc Multiplex PCR-identified cutaneous tuberculosis evoked by Mycobacterium bovis BCG vaccination in a healthy baby
    Tatsuma Okazaki
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Seiryo machi 1 1, Aoba ku, Sendai 980 8574, Japan
    J Clin Microbiol 43:523-5. 2005
    ..A healthy baby with a developing abscess is described. A multiplex PCR identified the abscess as originating from M. bovis BCG Tokyo 172...
  7. ncbi request reprint [Surgical site infection by bacillus Calmette-Guerin (BCG) after radical cystectomy, occurring after intravesical bcg therapy: a case report]
    Takashi Muranaka
    Department of Urology, Sapporo Medical University
    Hinyokika Kiyo 53:581-4. 2007
    ..He recovered from the SSI soon after anti-tuberculosis chemotherapy was begun. We discuss the requirements for more prompt diagnosis of SSI by BCG by analysis of this case...
  8. doi request reprint Report of an international collaborative study to establish the suitability of using modified ATP assay for viable count of BCG vaccine
    Mei M Ho
    Bacteriology Division, NIBSC, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Vaccine 26:4754-7. 2008
    ..A collaborative study will be carried out using this modified ATP assay in parallel with the cultural viable count method in the establishment of the replacement of the WHO International Reference Preparation of BCG vaccine...
  9. ncbi request reprint Quantitative analyses of mRNA and protein levels of neurotrophin-3 in the rat retina during postnatal development and aging
    Masaaki Seki
    Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951 8585, Japan
    Jpn J Ophthalmol 48:460-4. 2004
    ..In this study, we sought to elucidate changes in the levels of neurotrophin-3 (NT-3) in the rat retina throughout postnatal development and aging...
  10. ncbi request reprint BDNF is upregulated by postnatal development and visual experience: quantitative and immunohistochemical analyses of BDNF in the rat retina
    Masaaki Seki
    Department of Molecular Neurobiology, Brain Research Institute, and Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Invest Ophthalmol Vis Sci 44:3211-8. 2003
    ..This study sought to elucidate changes in the levels and distribution of brain-derived neurotrophic factor (BDNF) in the retina throughout aging and depending on visual experience...