Mamoru Kawahara

Summary

Affiliation: Japan BCG Central Laboratory
Country: Japan

Publications

  1. doi request reprint Recombinant Mycobacterium bovis BCG vector system expressing SIV Gag protein stably and persistently induces antigen-specific humoral immune response concomitant with IFN gamma response, even at three years after immunization
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Clin Immunol 129:492-8. 2008
  2. ncbi request reprint Intradermal and oral immunization with recombinant Mycobacterium bovis BCG expressing the simian immunodeficiency virus Gag protein induces long-lasting, antigen-specific immune responses in guinea pigs
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Tokyo 162 8640, Japan
    Clin Immunol 119:67-78. 2006
  3. ncbi request reprint Combined intrarectal/intradermal inoculation of recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces enhanced immune responses against the inserted HIV-1 V3 antigen
    Mamoru Kawahara
    AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Vaccine 21:158-66. 2002
  4. ncbi request reprint Oral recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing HIV-1 antigens as a freeze-dried vaccine induces long-term, HIV-specific mucosal and systemic immunity
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo, 162 8640, Japan
    Clin Immunol 105:326-31. 2002
  5. pmc Dynamics of gamma interferon, interleukin-12 (IL-12), IL-10, and transforming growth factor beta mRNA expression in primary Mycobacterium bovis BCG infection in guinea pigs measured by a real-time fluorogenic reverse transcription-PCR assay
    Mamoru Kawahara
    National Institute of Infectious Diseases, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 70:6614-20. 2002

Detail Information

Publications5

  1. doi request reprint Recombinant Mycobacterium bovis BCG vector system expressing SIV Gag protein stably and persistently induces antigen-specific humoral immune response concomitant with IFN gamma response, even at three years after immunization
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Clin Immunol 129:492-8. 2008
    ..This suggests that the rBCG vector system expressing an appropriate size of foreign antigen gene should be suited for the induction of the antigen-specific humoral immunity concomitant with an IFN gamma response...
  2. ncbi request reprint Intradermal and oral immunization with recombinant Mycobacterium bovis BCG expressing the simian immunodeficiency virus Gag protein induces long-lasting, antigen-specific immune responses in guinea pigs
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Tokyo 162 8640, Japan
    Clin Immunol 119:67-78. 2006
    ....
  3. ncbi request reprint Combined intrarectal/intradermal inoculation of recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces enhanced immune responses against the inserted HIV-1 V3 antigen
    Mamoru Kawahara
    AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Vaccine 21:158-66. 2002
    ..Thus, inoculation with rBCG-HIV by combined routes represents an effective vaccination strategy to elicit high levels of HIV-1-specific immune responses...
  4. ncbi request reprint Oral recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing HIV-1 antigens as a freeze-dried vaccine induces long-term, HIV-specific mucosal and systemic immunity
    Mamoru Kawahara
    National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo, 162 8640, Japan
    Clin Immunol 105:326-31. 2002
    ....
  5. pmc Dynamics of gamma interferon, interleukin-12 (IL-12), IL-10, and transforming growth factor beta mRNA expression in primary Mycobacterium bovis BCG infection in guinea pigs measured by a real-time fluorogenic reverse transcription-PCR assay
    Mamoru Kawahara
    National Institute of Infectious Diseases, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 70:6614-20. 2002
    ..Thus, our quantitative assay would be of use for the development of vaccines using guinea pig models...