Makoto Sasaki

Summary

Affiliation: Iwate Medical University
Country: Japan

Publications

  1. doi request reprint Penumbral imaging by using perfusion computed tomography and perfusion-weighted magnetic resonance imaging: current concepts
    Makoto Sasaki
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Nishitokuta, Yahaba, Japan Electronic address
    J Stroke Cerebrovasc Dis 22:1212-5. 2013
  2. doi request reprint Assessment of the accuracy of a Bayesian estimation algorithm for perfusion CT by using a digital phantom
    Makoto Sasaki
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 2 1 1 Nishitokuta, Yahaba, 028 3694, Japan
    Neuroradiology 55:1197-203. 2013
  3. pmc Prediction of infarct volume and neurologic outcome by using automated multiparametric perfusion-weighted magnetic resonance imaging in a primate model of permanent middle cerebral artery occlusion
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, Morioka, Japan
    J Cereb Blood Flow Metab 31:448-56. 2011
  4. ncbi request reprint Visual discrimination among patients with depression and schizophrenia and healthy individuals using semiquantitative color-coded fast spin-echo T1-weighted magnetic resonance imaging
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neuroradiology 52:83-9. 2010
  5. ncbi request reprint Combining time-resolved and single-phase 3D techniques in contrast-enhanced carotid MR angiography
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, Morioka, Japan
    Magn Reson Med Sci 1:1-6. 2002
  6. ncbi request reprint Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 50:117-22. 2008
  7. ncbi request reprint Standardizing display conditions of diffusion-weighted images using concurrent b0 images: a multi-vendor multi-institutional study
    Makoto Sasaki
    Department of Radiology, Iwate Medical University School of Medicine, Morioka, Japan
    Magn Reson Med Sci 6:133-7. 2007
  8. ncbi request reprint High-field MRI of the central nervous system: current approaches to clinical and microscopic imaging
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Magn Reson Med Sci 2:133-9. 2003
  9. ncbi request reprint Enhancement effects and relaxivities of gadolinium-DTPA at 1.5 versus 3 Tesla: a phantom study
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, School of Medicine, Morioka, Japan
    Magn Reson Med Sci 4:145-9. 2005
  10. ncbi request reprint Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Radiology 249:624-30. 2008

Detail Information

Publications101 found, 100 shown here

  1. doi request reprint Penumbral imaging by using perfusion computed tomography and perfusion-weighted magnetic resonance imaging: current concepts
    Makoto Sasaki
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Nishitokuta, Yahaba, Japan Electronic address
    J Stroke Cerebrovasc Dis 22:1212-5. 2013
    ..These research initiatives can promote further multicenter trials on recanalization therapies by providing accurate inclusion/exclusion criteria for appropriate patient selection. ..
  2. doi request reprint Assessment of the accuracy of a Bayesian estimation algorithm for perfusion CT by using a digital phantom
    Makoto Sasaki
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 2 1 1 Nishitokuta, Yahaba, 028 3694, Japan
    Neuroradiology 55:1197-203. 2013
    ..Hence, we compared the accuracy of the Bayesian and deconvolution algorithms by using a digital phantom...
  3. pmc Prediction of infarct volume and neurologic outcome by using automated multiparametric perfusion-weighted magnetic resonance imaging in a primate model of permanent middle cerebral artery occlusion
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, Morioka, Japan
    J Cereb Blood Flow Metab 31:448-56. 2011
    ..At optimum threshold, AT, CBV, TTP, T(max), and deconvolution CBF can accurately predict the final infarct volume and neurologic outcome in monkeys with permanent MCA occlusion...
  4. ncbi request reprint Visual discrimination among patients with depression and schizophrenia and healthy individuals using semiquantitative color-coded fast spin-echo T1-weighted magnetic resonance imaging
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neuroradiology 52:83-9. 2010
    ..We investigated whether visual interpretation of semiquantitative color maps can be used for discriminating between depressive and schizophrenic patients and healthy individuals...
  5. ncbi request reprint Combining time-resolved and single-phase 3D techniques in contrast-enhanced carotid MR angiography
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, Morioka, Japan
    Magn Reson Med Sci 1:1-6. 2002
    ..The combined use of time-resolved and single-phase 3D MRA is a feasible technique for obtaining selective arterial images without the use of special applications or hardware...
  6. ncbi request reprint Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 50:117-22. 2008
    ....
  7. ncbi request reprint Standardizing display conditions of diffusion-weighted images using concurrent b0 images: a multi-vendor multi-institutional study
    Makoto Sasaki
    Department of Radiology, Iwate Medical University School of Medicine, Morioka, Japan
    Magn Reson Med Sci 6:133-7. 2007
    ..To establish a practical method that uses concurrent b0 images to standardize the display conditions for diffusion-weighted images (DWI) that vary among institutions and interpreters...
  8. ncbi request reprint High-field MRI of the central nervous system: current approaches to clinical and microscopic imaging
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Magn Reson Med Sci 2:133-9. 2003
    ..Technological advances tailored to high-field systems, as well as the accumulation of scientific evidence, will be necessary to establish its predominance over conventional MRI...
  9. ncbi request reprint Enhancement effects and relaxivities of gadolinium-DTPA at 1.5 versus 3 Tesla: a phantom study
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, School of Medicine, Morioka, Japan
    Magn Reson Med Sci 4:145-9. 2005
    ..5 and 3 Tesla (T) and to elucidate the contribution of the high magnetic field to contrast enhancement in spin-echo (SE) and gradient-echo (GRE) images...
  10. ncbi request reprint Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Radiology 249:624-30. 2008
    ..To determine whether and to what degree absolute apparent diffusion coefficient (ADC) values vary between different imagers, vendors, field strengths, and intraimager conditions...
  11. doi request reprint Monoamine neurons in the human brain stem: anatomy, magnetic resonance imaging findings, and clinical implications
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, Uchimaru, Morioka, Japan
    Neuroreport 19:1649-54. 2008
    ..This technique seems to be promising for the noninvasive evaluation of the pathological or functional changes in the monoamine system that occur in degenerative and psychiatric disorders...
  12. ncbi request reprint Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, Morioka, Japan
    Neuroreport 17:1215-8. 2006
    ....
  13. ncbi request reprint Disorganised unilateral cerebellar folia: a mild form of cerebellar cortical dysplasia?
    M Sasaki
    Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neuroradiology 43:151-5. 2001
    ..These patients have no cerebellar neurological deficit. This rare abnormality is probably a maldevelopment of the hemispheric part of the posterior lobe of the developing cerebellum, and no clinical significance can be elicited...
  14. doi request reprint Tracer delay-insensitive algorithm can improve reliability of CT perfusion imaging for cerebrovascular steno-occlusive disease: comparison with quantitative single-photon emission CT
    M Sasaki
    Advanced Medical Research Center, Iwate Medical University, Morioka, Japan
    AJNR Am J Neuroradiol 30:188-93. 2009
    ....
  15. ncbi request reprint Discriminating between silent cerebral infarction and deep white matter hyperintensity using combinations of three types of magnetic resonance images: a multicenter observer performance study
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, Uchimaru, Morioka, Japan
    Neuroradiology 50:753-8. 2008
    ....
  16. ncbi request reprint MRI identification of dorsal hippocampus homologue in human brain
    Makoto Sasaki
    Department of Radiology, Iwate Medical University, Morioka 020 8505, Japan
    Neuroreport 15:2173-6. 2004
    ..These data may help in understanding phylogenetic, and in correlating results from animal experiments with clinical findings on the functions and pathologies of the human hippocampus...
  17. doi request reprint Brain temperature measured by using proton MR spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy
    Toshiyuki Murakami
    Department of Neurosurgery and Advanced Medical Research Center, Iwate Medical University, Morioka 020 8505, Japan
    Radiology 256:924-31. 2010
    ..To determine whether brain temperature measured by using preoperative proton magnetic resonance (MR) spectroscopy could help identify patients at risk for cerebral hyperperfusion after carotid endarterectomy (CEA)...
  18. doi request reprint Assessment of damage to cerebral white matter fiber in the subacute phase after carbon monoxide poisoning using fractional anisotropy in diffusion tensor imaging
    Takaaki Beppu
    Departments of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, 020 8505, Japan
    Neuroradiology 52:735-43. 2010
    ..We examined whether diffusion tensor imaging can sensitively represent damage to fibers of the centrum semiovale in the subacute phase after CO intoxication...
  19. ncbi request reprint Preoperative single-slab 3D time-of-flight magnetic resonance angiography predicts development of new cerebral ischemic events after carotid endarterectomy. Clinical article
    Taro Suzuki
    Department of Neurosurgery, Advanced Medical Center, Iwate Medical University, Morioka, Japan
    J Neurosurg 111:141-6. 2009
    ..The purpose of the present study was to determine whether, on preoperative MR angiography, the signal intensity of the MCA can be used to identify patients at risk for development of cerebral ischemic events after CEA...
  20. doi request reprint Intentional hypertension during dissection of carotid arteries in endarterectomy prevents postoperative development of new cerebral ischemic lesions caused by intraoperative microemboli
    Masakazu Kobayashi
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    Neurosurgery 69:301-7. 2011
    ....
  21. doi request reprint Differences in CT perfusion maps generated by different commercial software: quantitative analysis by using identical source data of acute stroke patients
    Kohsuke Kudo
    Advanced Medical Research Center, Iwate Medical University 19 1 Uchimaru, Morioka 020 8505, Japan
    Radiology 254:200-9. 2010
    ....
  22. doi request reprint Postoperative increase in cerebral white matter fractional anisotropy on diffusion tensor magnetic resonance imaging is associated with cognitive improvement after uncomplicated carotid endarterectomy: tract-based spatial statistics analysis
    Yuiko Sato
    Department of Neurosurgery, Iwate Medical University School of Medicine, Morioka, Japan Division of Ultra High Field MRI and Department of Radiology, Iwate Medical University School of Medicine, Morioka, Japan Department of Disaster Medicine, Iwate Medical University School of Medicine, Morioka, Japan
    Neurosurgery 73:592-8; discussion 598-9. 2013
    ..Fractional anisotropy (FA) values in the cerebral white matter derived from diffusion tensor magnetic resonance imaging (DTI) correlate with cognitive function in patients with various central nervous system diseases...
  23. doi request reprint Postoperative cerebral white matter damage associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: a diffusion tensor magnetic resonance imaging study
    Takamasa Nanba
    Advanced Research Center, Iwate Medical University, Morioka, Japan
    Cerebrovasc Dis 34:358-67. 2012
    ....
  24. ncbi request reprint Proton magnetic resonance spectroscopy and diffusion-weighted imaging of tumefactive demyelinating plaque
    Kazuki Masu
    Department of Neurosurgery, Iwate Medical University, Morioka, Iwate
    Neurol Med Chir (Tokyo) 49:430-3. 2009
    ....
  25. ncbi request reprint Use of neuromelanin-sensitive MRI to distinguish schizophrenic and depressive patients and healthy individuals based on signal alterations in the substantia nigra and locus ceruleus
    Eri Shibata
    Department of Neuropsychiatry, Iwate Medical University School of Medicine, Morioka, Japan
    Biol Psychiatry 64:401-6. 2008
    ....
  26. ncbi request reprint Improved geometric distortion in coronal diffusion-weighted and diffusion tensor imaging using a whole-brain isotropic-voxel acquisition technique at 3 Tesla
    Shunrou Fujiwara
    Advanced Medical Research Center, Iwate Medical University, Takizawa, Iwate, Japan
    Magn Reson Med Sci 6:127-32. 2007
    ..We used a whole-brain, isotropic-voxel acquisition technique to improve the geometric distortion in diffusion-weighted (DWI) and diffusion tensor imaging (DTI) in coronal directions, which is remarkable at high magnetic fields...
  27. ncbi request reprint Diffusion anisotropy color-coded map of cerebral white matter: quantitative comparison between orthogonal anisotropic diffusion-weighted imaging and diffusion tensor imaging
    Ikuko Uwano
    Division of Ultra High Field, Institute for Biomedical Sciences, Iwate Medical University, Uchimaru, Morioka, Japan
    J Neuroimaging 23:197-201. 2013
    ..Hence, we attempted to determine whether 3DAC is comparable to a diffusion tensor imaging (DTI) color map...
  28. doi request reprint CT and MR perfusion can discriminate severe cerebral hypoperfusion from perfusion absence: evaluation of different commercial software packages by using digital phantoms
    Ikuko Uwano
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 54:467-74. 2012
    ..Hence, we examined whether commercial software can visualize very low cerebral blood flow (CBF) and cerebral blood volume (CBV) by creating and using digital phantoms...
  29. doi request reprint Mapping of cerebral oxygen extraction fraction changes with susceptibility-weighted phase imaging
    Yuri Zaitsu
    Department of Radiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiology 261:930-6. 2011
    ..To develop a map to detect changes in oxygen extraction fraction (OEF) utilizing susceptibility-weighted (SW) phase images and to correlate such changes in OEF with those in cerebral blood flow (CBF)...
  30. ncbi request reprint Quantitative analysis of magnetic resonance imaging susceptibility artifacts caused by neurosurgical biomaterials: comparison of 0.5, 1.5, and 3.0 Tesla magnetic fields
    Hideki Matsuura
    Department of Neurosurgery, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 45:395-8; discussion 398-9. 2005
    ..The artifacts caused by biomaterials except ceramic increase with the magnetic field strength. Ceramic instrumentation will minimize artifacts in all magnetic fields...
  31. doi request reprint Prediction of malignancy grading using computed tomography perfusion imaging in nonenhancing supratentorial gliomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurooncol 103:619-27. 2011
    ..CTP offers a useful method for differentiating between G3 and G2 in nonenhancing gliomas...
  32. pmc Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol 259:1698-705. 2012
    ..The present results suggest that FA in the centrum semiovale offers a quantitative indicator of the extent of demyelination in damaged CWM during the subacute phase in CO-poisoned patients...
  33. pmc Accuracy and reliability assessment of CT and MR perfusion analysis software using a digital phantom
    Kohsuke Kudo
    Division of Ultra High Field MRI and Department of Radiology, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Radiology 267:201-11. 2013
    ....
  34. doi request reprint Clinical and angiographic long-term outcomes of vertebral artery-subclavian artery transposition to treat symptomatic stenosis of vertebral artery origin
    Shunsuke Kakino
    Departments of Neurosurgery, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    J Neurosurg 110:943-7. 2009
    ..Therefore, the authors assessed the long-term clinical and angiographic outcomes in patients after VA-subclavian artery (SA) transposition...
  35. doi request reprint Preoperative cerebrovascular reactivity to acetazolamide measured by brain perfusion SPECT predicts development of cerebral ischemic lesions caused by microemboli during carotid endarterectomy
    Kenta Aso
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka, 020 8505, Japan
    Eur J Nucl Med Mol Imaging 36:294-301. 2009
    ....
  36. doi request reprint 1H-magnetic resonance spectroscopy indicates damage to cerebral white matter in the subacute phase after CO poisoning
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol Neurosurg Psychiatry 82:869-75. 2011
    ..The authors examined whether (1)H-magnetic resonance spectroscopy (MRS) can identify damage to the centrum semiovale in the subacute phase after CO exposure...
  37. ncbi request reprint Intraoperative microemboli and low middle cerebral artery blood flow velocity are additive in predicting development of cerebral ischemic events after carotid endarterectomy
    Kuniaki Ogasawara
    Department of Neurosurgery, School of Medicine, Iwate Medical University, Morioka, Japan
    Stroke 39:3088-91. 2008
    ..The purpose of this study was to determine whether these events correlate with middle cerebral artery blood flow velocity...
  38. doi request reprint Changes in substantia nigra and locus coeruleus in patients with early-stage Parkinson's disease using neuromelanin-sensitive MR imaging
    Chigumi Ohtsuka
    Department of Neurology and Gerontology, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neurosci Lett 541:93-8. 2013
    ....
  39. ncbi request reprint Quantitative assessment of changes in carotid plaques during cilostazol administration using three-dimensional ultrasonography and non-gated magnetic resonance plaque imaging
    Mao Yamaguchi
    Department of Neurology and Gerontology, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 54:939-45. 2012
    ..Hence, we quantitatively investigated the changes that occur within carotid plaques during cilostazol administration using three-dimensional (3D) ultrasonography (US) and non-gated magnetic resonance (MR) plaque imaging...
  40. doi request reprint Detecting damaged regions of cerebral white matter in the subacute phase after carbon monoxide poisoning using voxel-based analysis with diffusion tensor imaging
    Shunrou Fujiwara
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neuroradiology 54:681-9. 2012
    ....
  41. pmc Hemorrhagic infarction at 33 days after birth in a healthy full-term neonate
    Yoshitaka Kubo
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    Vasc Health Risk Manag 7:667-70. 2011
    ..Patent foramen ovale may have been present and this may have led to spontaneous paradoxical cerebral embolism followed by hemorrhagic infarction...
  42. ncbi request reprint Preoperative imaging of superficially located glioma resection using short inversion-time inversion recovery images in high-field magnetic resonance imaging
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimau, Morioka 020 8505, Japan
    Clin Neurol Neurosurg 109:327-34. 2007
    ..The aim of the present study is to evaluate the effectiveness of STIR in imaging tumor involvement of the cortical surface and intra-axial structures, its usefulness in the resection of superficially located gliomas...
  43. doi request reprint Difference in tracer delay-induced effect among deconvolution algorithms in CT perfusion analysis: quantitative evaluation with digital phantoms
    Kohsuke Kudo
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Radiology 251:241-9. 2009
    ..bSVD was superior to sSVD and dSVD for avoiding the tracer delay-induced effects in CT perfusion imaging...
  44. ncbi request reprint Age-related changes in locus ceruleus on neuromelanin magnetic resonance imaging at 3 Tesla
    Eri Shibata
    Department of Radiology, Iwate Medical University, Morioka, Japan
    Magn Reson Med Sci 5:197-200. 2006
    ..To investigate age-related changes in the locus ceruleus (LC) in healthy subjects using neuromelanin magnetic resonance (MR) imaging at 3 Tesla...
  45. doi request reprint Non-invasive measurement of oxygen saturation in the spinal vein using SWI: quantitative evaluation under conditions of physiological and caffeine load
    Noriyuki Fujima
    Department of Radiology, Hokkaido University Graduate School of Medicine, Hokkaido, Japan
    Neuroimage 54:344-9. 2011
    ..We showed changes in oxygen saturation under physiological as well as caffeine load and suggest that this method is a useful tool for the clinical evaluation of spinal cord oxygenation...
  46. ncbi request reprint Bayesian analysis of perfusion-weighted imaging to predict infarct volume: comparison with singular value decomposition
    Kohsuke Kudo
    Division of Ultrahigh Field MRI, Institute of Biomedical Sciences, Iwate Medical University
    Magn Reson Med Sci 13:45-50. 2014
    ....
  47. pmc Susceptibility of Tmax to tracer delay on perfusion analysis: quantitative evaluation of various deconvolution algorithms using digital phantoms
    Kohsuke Kudo
    Advanced Medical Research Center, Iwate Medical University, Uchimaru, Morioka, Japan
    J Cereb Blood Flow Metab 31:908-12. 2011
    ..The T(max) is a parameter highly dependent on tracer delays and deconvolution algorithm...
  48. doi request reprint Carotid plaque signal differences among four kinds of T1-weighted magnetic resonance imaging techniques: a histopathological correlation study
    Ayumi Saito
    Department of Neurology and Gerontology, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 54:1187-94. 2012
    ..Here, we directly compared four kinds of T1-weighted (T1W) imaging techniques with pathological findings in patients with carotid stenosis...
  49. ncbi request reprint Noninvasive evaluation of collateral blood flow through circle of willis in cervical carotid stenosis using selective magnetic resonance angiography
    Kenji Ito
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Yahaba, Japan
    J Stroke Cerebrovasc Dis 23:1019-23. 2014
    ..Hence, by using a newly developed selective MRA technique, we attempted to visualize collaterals via the circle of Willis in patients with ICA stenosis...
  50. ncbi request reprint Intensity inhomogeneity correction for magnetic resonance imaging of human brain at 7T
    Ikuko Uwano
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Yahaba, Iwate 028 3694, Japan
    Med Phys 41:022302. 2014
    ..To evaluate the performance and efficacy for intensity inhomogeneity correction of various sequences of the human brain in 7T MRI using the extended version of the unified segmentation algorithm...
  51. doi request reprint 3D neuromelanin-sensitive magnetic resonance imaging with semi-automated volume measurement of the substantia nigra pars compacta for diagnosis of Parkinson's disease
    Kimihiro Ogisu
    Department of Radiology, Hokkaido University Graduate School of Medicine, N 15, W 7, Kita ku, Sapporo, Hokkaido 060 8638, Japan
    Neuroradiology 55:719-24. 2013
    ..In this study, we aimed to apply a 3D turbo field echo (TFE) sequence for neuromelanin-sensitive MRI and to evaluate the diagnostic performance of semi-automated method for measurement of SNc volume in patients with PD...
  52. ncbi request reprint Evaluating middle cerebral artery atherosclerotic lesions in acute ischemic stroke using magnetic resonance T1-weighted 3-dimensional vessel wall imaging
    Tatsunori Natori
    Department of Neurology and Gerontology, Iwate Medical University, Morioka, Japan Electronic address
    J Stroke Cerebrovasc Dis 23:706-11. 2014
    ..Here, we used a 3-dimensional vessel wall imaging (3D-VWI) technique to evaluate intracranial arterial wall changes in acute stroke...
  53. doi request reprint Proton magnetic resonance spectroscopic images in preterm infants with bilirubin encephalopathy
    Atsushi Kamei
    Department of Pediatrics, School of Medicine, Iwate Medical University, Morioka, Japan
    J Pediatr 160:342-4. 2012
    ..An increased glutamate/glutamine complex/creatine ratio was found in the basal ganglia. Chemical metabolic abnormalities of the basal ganglia were clearly demonstrated by color-coded metabolite images...
  54. doi request reprint High-resolution diffusion tensor imaging for the detection of diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia caused by neurovascular compression
    Shunrou Fujiwara
    Advanced Medical Research Center, Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neuroimaging 21:e102-8. 2011
    ..To detect diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia (TN) caused by neurovascular compression (NVC) by using a high-resolution diffusion tensor imaging (HR-DTI) technique...
  55. doi request reprint Magnetic resonance imaging in patients with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy
    Ryounoshin Hirooka
    Department of Neurosurgery, Tochinai Daini Hospital, Morioka, Japan
    J Neurosurg 108:1178-83. 2008
    ..The purpose of the present study is to investigate structural brain damage seen on magnetic resonance (MR) images obtained in patients with cerebral hyperperfusion and cognitive impairment after CEA...
  56. ncbi request reprint Brain temperature measured using proton MR spectroscopy detects cerebral hemodynamic impairment in patients with unilateral chronic major cerebral artery steno-occlusive disease: comparison with positron emission tomography
    Daiya Ishigaki
    Advanced Research Center, School of Medicine, Iwate Medical University, Morioka, Japan
    Stroke 40:3012-6. 2009
    ....
  57. ncbi request reprint Early revascularization in a patient with perfusion computed tomography/diffusion-weighted magnetic resonance imaging mismatch secondary to acute vertebral artery occlusion. Case report
    Kuniaki Ogasawara
    Department of Neurosurgery, Iwate Medical University, Uchimaru, Morioka, Japan
    Neurol Med Chir (Tokyo) 45:306-10. 2005
    ..Early revascularization in a patient with perfusion CT/diffusion-weighted MR imaging mismatch following acute vertebrobasilar stroke can lead to improvement in cerebral perfusion and neurological function...
  58. ncbi request reprint The substantia nigra in Parkinson disease: proton density-weighted spin-echo and fast short inversion time inversion-recovery MR findings
    Hirobumi Oikawa
    Department of Radiology, Iwate Medical University, Uchimaru, Morioka, Japan
    AJNR Am J Neuroradiol 23:1747-56. 2002
    ....
  59. ncbi request reprint Reduced signal of locus ceruleus in depression in quantitative neuromelanin magnetic resonance imaging
    Eri Shibata
    Department of Radiology, Center for EM and Bio Imaging Research, Iwate Medical University, Morioka, Japan
    Neuroreport 18:415-8. 2007
    ..Neuromelanin-magnetic resonance imaging can be used to visualize abnormalities in the locus ceruleus of depressive patients...
  60. ncbi request reprint Differentiation of early-stage parkinsonisms using neuromelanin-sensitive magnetic resonance imaging
    Chigumi Ohtsuka
    Department of Neurology and Gerontology, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan Electronic address
    Parkinsonism Relat Disord 20:755-60. 2014
    ....
  61. ncbi request reprint Detection of active plaques in multiple sclerosis using susceptibility-weighted imaging: comparison with gadolinium-enhanced MR imaging
    Masako Suzuki
    Department of Neurology, Iwate Medical University, Morioka, Japan
    Magn Reson Med Sci 10:185-92. 2011
    ..We evaluated active plaque detection by SW compared with contrast-enhanced MR imaging...
  62. doi request reprint Detection of normal spinal veins by using susceptibility-weighted imaging
    Kinya Ishizaka
    Department of Radiology, Hokkaido University Hospital, Sapporo, Japan
    J Magn Reson Imaging 31:32-8. 2010
    ..To evaluate the visualization of the spinal veins using susceptibility-weighted imaging (SWI)...
  63. ncbi request reprint Utility of three-dimensional anisotropy contrast magnetic resonance axonography for determining condition of the pyramidal tract in glioblastoma patients with hemiparesis
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1, Uchimaru, 020 8505 Morioka, Japan
    J Neurooncol 73:137-44. 2005
    ..This study evaluated condition of the pyramidal tract using 3DAC in glioblastoma patients with hemiparesis...
  64. doi request reprint Altered carotid plaque signal among different repetition times on T1-weighted magnetic resonance plaque imaging with self-navigated radial-scan technique
    Shinsuke Narumi
    Department of Neurology and Gerontology, Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 52:285-90. 2010
    ..Hence, we investigated whether differences in TR causes signal alterations of the carotid plaque by using a non-gated plaque imaging technique...
  65. ncbi request reprint Quantification of susceptibility artifacts produced on high-field magnetic resonance images by various biomaterials used for neurosurgical implants. Technical note
    Hideki Matsuura
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurosurg 97:1472-5. 2002
    ..Little difference was observed between the artifact diameters associated with pure titanium and titanium alloy. Ceramics are the most suitable biomaterials for minimizing artifacts in high-field MR imaging...
  66. ncbi request reprint [Neuroimaging using ultrahigh-field magnetic resonance imaging at 7 tesla: current concepts]
    Makoto Sasaki
    Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Iwate, Japan
    Brain Nerve 64:1057-62. 2012
    ....
  67. ncbi request reprint Substantia innominata: MR findings in Parkinson's disease
    Hirobumi Oikawa
    Iwate Medical University, 19 1 Uchimaru, Morioka, Japan
    Neuroradiology 46:817-21. 2004
    ..Atrophy of the substantia innominata was demonstrated, especially in PD patients with cognitive impairment, on coronal MR images, and this is compatible with the previous pathological reports...
  68. ncbi request reprint Improvement in image quality of noncontrast head images in multidetector-row CT by volume helical scanning with a three-dimensional denoising filter
    Tadashi Sasaki
    Center for Radiological Sciences, Iwate Medical University Hospital, 19 1 Uchimaru, Morioka, 020 8505, Japan
    Radiat Med 25:368-72. 2007
    ..We applied a technique combining volume helical scanning with a three-dimensional (3D) denoising filter...
  69. ncbi request reprint Feasibility of 1.6-mm isotropic voxel diffusion tensor tractography in depicting limbic fibers
    Shunrou Fujiwara
    Advanced Medical Research Center, Iwate Medical University, Takizawa, Japan
    Neuroradiology 50:131-6. 2008
    ..We attempted to assess the feasibility of a 1.6-mm isotropic voxel diffusion tensor imaging (DTI) tractography at 3T in visualizing nerve bundles in the limbic system...
  70. ncbi request reprint [Pitfalls in the interpretation of central nervous system disorders from structural magnetic resonance images]
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Brain Nerve 62:469-75. 2010
    ..However, these 2 techniques may cause artifacts in which the signal intensity of the subarachnoid space is increased and a false diagnosis of SAH can be obtained under certain inappropriate scanning parameters, which should be avoided...
  71. pmc Identification of Abiotrophia adiacens and Abiotrophia defectiva by 16S rRNA gene PCR and restriction fragment length polymorphism analysis
    Y Ohara-Nemoto
    Department of Microbiology, School of Dentistry, Iwate Medical University, Morioka, Japan
    J Clin Microbiol 35:2458-63. 1997
    ..1 pg of genomic DNA, as assessed by using the digoxigenin-labeling DNA detection system. Thus, the PCR-RFLP analysis that we developed is applicable for the routine detection of Abiotrophia from clinical specimens...
  72. ncbi request reprint Virtual CT endoscopy of ossicles in the middle ear
    T Nakasato
    Department of Radiology, Iwate Medical University, School of Medicine, 19 1 Uchimaru, Morioka 020 8505, Iwate, Japan
    Clin Imaging 25:171-7. 2001
    ....
  73. ncbi request reprint The circuit of Papez in mesial temporal sclerosis: MRI
    H Oikawa
    Department of Radiology, Iwate Medical University, Morioka, Japan
    Neuroradiology 43:205-10. 2001
    ..Changes in the parahippocampal gyrus, including the entorhinal cortex and subiculum, in which forniceal fibres originate, may be crucial in causing abnormalities more distally in the circuit...
  74. ncbi request reprint MR angiography and CT angiography of the artery of Adamkiewicz: noninvasive preoperative assessment of thoracoabdominal aortic aneurysm
    Kunihiro Yoshioka
    Department of Radiology, Memorial Heart Center, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Radiographics 23:1215-25. 2003
    ..However, further studies will be needed to assess the efficacy of these modalities in decreasing surgical risk...
  75. ncbi request reprint Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan
    Akira Ogawa
    Iwate Medical University School of Medicine, Morioka, Japan
    Stroke 38:2633-9. 2007
    ..The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT) Japan was organized to determine the safety and clinical efficacy of intraarterial infusion of urokinase (UK) in patients with stroke within 6 hours of onset...
  76. ncbi request reprint [3D CT angiography (CTA)]
    Makoto Sasaki
    Department of Radiology, Iwate Medical University
    Nihon Rinsho 64:323-6. 2006
  77. ncbi request reprint [Neuroimaging of idiopathic normal pressure hydrocephalus--current concepts]
    Makoto Sasaki
    Advanced Medical Research Center, Iwate Medical University, Uchimaru, Morioka 020 8505, Japan
    Brain Nerve 60:241-5. 2008
    ....
  78. ncbi request reprint Transient decrease in cerebral white matter diffusivity on MR imaging in human herpes virus-6 encephalopathy
    Manami Akasaka
    Department of Pediatrics, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Brain Dev 27:30-3. 2005
    ..The transient decrease in the cerebral white matter diffusivity seen in the present case may reflect axonal involvement secondary to the glial or neuronal damage in HHV-6 encephalopathy...
  79. ncbi request reprint Evaluation of vasospasm after subarachnoid hemorrhage by use of multislice computed tomographic angiography
    Yasunari Otawara
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    Neurosurgery 51:939-42; discussion 942-3. 2002
    ....
  80. ncbi request reprint [CT and MRI of the central nervous system: current concepts]
    Makoto Sasaki
    Department of Radiology, Iwate Medical University
    Rinsho Shinkeigaku 47:919-20. 2007
    ..Standardization techniques for the stroke CT and MRI introduced by ASIST-Japan can reduce inter-institutional and intervendor differences, and helps in facilitating multicenter trials concerning acute stroke management...
  81. ncbi request reprint [CT findings of intracerebral hemorrhage]
    Makoto Sasaki
    Department of Radiology, Iwate Medical University
    Nihon Rinsho 64:325-8. 2006
  82. ncbi request reprint Streptococcus anginosus infection in oral cancer and its infection route
    M Sasaki
    Department of Oral Microbiology, Iwate Medical University School of Dentistry, Morioka, Iwate, Japan
    Oral Dis 11:151-6. 2005
    ..To elucidate a possible involvement of Streptococcus anginosus in oral cancer, we assessed the frequency of S. anginosus infection in oral cancer tissues, and investigated its infection route...
  83. ncbi request reprint Antigenic characterisation of a novel Streptococcus anginosus antigen that induces nitric oxide synthesis by murine peritoneal exudate cells
    M Sasaki
    Department of Oral Microbiology, Iwate Medical University School of Dentistry, Morioka, Japan
    J Med Microbiol 50:952-8. 2001
    ..It is suggested that the protein molecule of SAA may exclusively induce NO synthesis, and its carbohydrate component(s) could have a relationship to cytokine production...
  84. ncbi request reprint [Abnormal magnetic resonance imaging in a child with Alice in Wonderland syndrome following Epstein-Barr virus infection]
    Atsushi Kamei
    Department of Pediatrics, Iwate Medical University, Morioka, Iwate
    No To Hattatsu 34:348-52. 2002
    ..We consider that any patient with symptoms of AIWS should have MRI because the abnormal MRI findings may disappear in a short period...
  85. ncbi request reprint Assessment of technetium-99m Technegas scintigraphy for ventilatory impairment in pulmonary emphysema: comparison of planar and SPECT images
    K Satoh
    Department of Radiology, Kagawa Medical University, School of Medicine, Japan
    Ann Nucl Med 11:109-13. 1997
    ..The degree of abnormal findings obtained by SPECT was equivalent to that obtained by CT in severe cases (6 cases, 30%). SPECT should be excluded in advanced stages as indicated by planar images...
  86. ncbi request reprint Air trapping on computed tomography images of healthy individuals: effects of respiration and body mass index
    M Hashimoto
    Department of Radiology, Akita University School of Medicine, Japan
    Clin Radiol 61:883-7. 2006
    ..To evaluate the relationships of changes in the lung area during respiration and of individual body mass index (BMI) to air trapping on expiratory computed tomography (CT) in young non-smoking adults of either gender...
  87. ncbi request reprint Cholangiolocellular carcinoma of the liver: CT and MR findings
    Y Fukukura
    Department of Radiology, Faculty of Medicine, Kagoshima University, Kagoshima City, Japan
    J Comput Assist Tomogr 24:809-12. 2000
    ..Therefore, helical CT and MRI features of these cholangiolocellular carcinomas were thought to be similar to those of cholangiocarcinoma...
  88. doi request reprint Simple assessment of cerebral hemodynamics using single-slab 3D time-of-flight MR angiography in patients with cervical internal carotid artery steno-occlusive diseases: comparison with quantitative perfusion single-photon emission CT
    R Hirooka
    Advanced Medical Research Center, Iwate Medical University, Hirosaki University, Japan
    AJNR Am J Neuroradiol 30:559-63. 2009
    ..The goal of this study was to compare the signal intensity of the MCA on MRA versus CVR quantified by perfusion single-photon emission CT (SPECT)...
  89. ncbi request reprint Refraction contrast 11x-magnified X-ray imaging of large objects by MIRRORCLE-type table-top synchrotron
    Toru Hirai
    Faculty of Science and Engineering, Ritsumeikan University, 1 1 1 Nojihigashi, Kusatsu, Shiga 525 8577, Japan
    J Synchrotron Radiat 13:397-402. 2006
    ..Soft tissue becomes highly visible as a natural consequence of refraction contrast when using hard X-rays for imaging. The authors believe that novel imaging provided by MIRRORCLE makes it a superior instrument for medical diagnosis...
  90. ncbi request reprint A hippocampal lesion detected by high-field 3 tesla magnetic resonance imaging in a patient with temporal lobe epilepsy
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Tohoku J Exp Med 205:287-91. 2005
    ..This is the first report detecting a hippocampal lesion by 3 T MRI, which could not be found by conventional 1.5 T MRI...
  91. ncbi request reprint Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)
    Makoto Sasaki
    Department of Biopharmaceutics, School of Pharmaceutical Sciences, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Biol Chem 277:6497-503. 2002
    ..The double-transfected MDCK II monolayer expressing both OATP2 and MRP2 may be used to analyze the hepatic vectorial transport of organic anions and to screen the transport profiles of new drug candidates...
  92. ncbi request reprint Advantages of endoscopic submucosal dissection over conventional endoscopic mucosal resection
    Takaya Shimura
    Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Gastroenterol Hepatol 22:821-6. 2007
    ..The efficacy and problems associated with endoscopic submucosal dissection were evaluated by comparison with conventional endoscopic mucosal resection...
  93. ncbi request reprint More than 13 years of hypereosinophila associated with clonal CD3-CD4+ lymphocytosis of TH2/TH0 type
    Koichi Sugimoto
    Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan
    Int J Hematol 75:281-4. 2002
    ....
  94. ncbi request reprint [Reduction of radiation exposure in CT perfusion study using a quantum de-noising filter]
    Tadashi Sasaki
    Center for Radiological Sciences, Iwate Medical University Hospital
    Nihon Hoshasen Gijutsu Gakkai Zasshi 60:1688-93. 2004
    ..The quantum de-noising filter is considered to be useful to reduce radiation exposure and to improve image quality in CT perfusion study...
  95. ncbi request reprint [H. pylori infection and abdominal symptoms]
    Takashi Joh
    Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences
    Nihon Rinsho 63:251-5. 2005
  96. ncbi request reprint Electron density measurement with dual-energy x-ray CT using synchrotron radiation
    Masami Torikoshi
    National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba shi 263 8555, Japan
    Phys Med Biol 48:673-85. 2003
    ..The tomographic image based on each of the electron densities and the effective atomic number presents a different feature of the material, and its contrast drastically differs from that in a conventional CT image...
  97. ncbi request reprint Serum from patients with multiple sclerosis downregulates occludin and VE-cadherin expression in cultured endothelial cells
    Alireza Minagar
    Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
    Mult Scler 9:235-8. 2003
    ..This downregulation of TJs proteins may, therefore, contribute to the disruption of the BBB in this condition...
  98. ncbi request reprint Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multid
    Soichiro Matsushima
    Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    J Pharmacol Exp Ther 314:1059-67. 2005
    ..This experimental system is very useful for identifying which transporters are involved in the biliary excretion of organic anions that cannot easily penetrate the plasma membrane...
  99. ncbi request reprint Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance as
    Makoto Sasaki
    Department of Biopharmaceutics, School of Pharmaceutical Sciences, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Mol Pharmacol 66:450-9. 2004
    ..The double-transfected MDCK II monolayer may be useful in analyzing the hepatic vectorial transport of organic anions and in predicting in vivo biliary clearance...
  100. ncbi request reprint The honeycomb gallbladder: a new category of acquired pseudo-multiseptate gallbladder
    Makoto Sasaki
    Department of Surgery, NTT West Nagasaki Hospital, 10 40 Oura, 850 0918, Nagasaki, Japan
    J Hepatobiliary Pancreat Surg 11:375-8. 2004
    ..Cholecystectomy should be the choice of treatment for honeycomb gallbladder from the viewpoint of clinical management...
  101. ncbi request reprint Autoimmune sclerosing cholangiopancreatitis with little pancreatic involvements by imaging findings
    Kazuki Hayashi
    Nagoya City University Graduate School of Medical Sciences, Department of Gastroenterology and Metabolism, Mizuho ku, Nagoya, Japan
    Hepatogastroenterology 54:2146-51. 2007
    ..We should recognize some sclerosing cholangitis cases showed no enlargement of the pancreas and no irregular narrowing of main pancreatic duct. We propose the concept of "autoimmune sclerosing cholangiopancreatitis"...