Detail Information
Publications
Dilated cardiomyopathy: a disease of the myocardiumAtsushi Sanbe
Department of Pharmacotherapeutics, School of Pharmacy, Iwate Medical University, Iwate 028 3694, Japan
Biol Pharm Bull 36:18-22. 2013..Thus, effective prognostic determination and appropriate cardiac care depend on accurate molecular and genetic diagnoses...
Cardioprotective effect of nicorandil, a mitochondrial ATP-sensitive potassium channel opener, prolongs survival in HSPB5 R120G transgenic miceAtsushi Sanbe
Department of Pharmacotherapeutics, School of Pharmacy, Iwate Medical University, Iwate, Japan
PLoS ONE 6:e18922. 2011..It is also known that progressive mitochondrial abnormalities and apoptotic cell death occur in the hearts of R120G TG mice. The role of mitochondrial dysfunction and apoptosis in disease progression, however, remains uncertain...
Molecular mechanisms of α-crystallinopathy and its therapeutic strategyAtsushi Sanbe
Department of Pharmacotherapeutics, School of Pharmacy, Iwate Medical University, Iwate, Japan
Biol Pharm Bull 34:1653-8. 2011..Moreover, recent findings have indicated that enhancement of HSP induction and inhibition of apoptotic cell death by mitochondrial protection may be a new therapeutic strategy for patients with crystallinopathy...
