Shigeki Machida

Summary

Affiliation: Iwate Medical University
Country: Japan

Publications

  1. ncbi Macular function evaluated by focal macular electroretinograms after reduced fluence photodynamic therapy in eyes with polypoidal choroidal vasculopathy
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Doc Ophthalmol 124:91-8. 2012
  2. ncbi Idiopathic choroidal neovascularization as an early manifestation of inflammatory chorioretinal diseases
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Retina 28:703-10. 2008
  3. ncbi Sensitivity and specificity of photopic negative response of focal electoretinogram to detect glaucomatous eyes
    S Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Br J Ophthalmol 94:202-8. 2010
  4. ncbi Photopic negative response of focal electoretinograms in glaucomatous eyes
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 49:5636-44. 2008
  5. ncbi Correlation between photopic negative response and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes
    Shigeki Machida
    Department of Ophthalmology, School of Medicine, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate, Japan
    Invest Ophthalmol Vis Sci 49:2201-7. 2008
  6. ncbi Melanoma-associated retinopathy associated with intranasal melanoma
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Uchimaru, Morioka, Japan
    Doc Ophthalmol 122:191-7. 2011
  7. ncbi Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation
    Tomoharu Nishimura
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 52:7610-7. 2011
  8. ncbi The Effect of intravitreal N-methyl-DL-aspartic acid on the electroretinogram in Royal College of surgeons rats
    Takayuki Ohzeki
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Jpn J Ophthalmol 51:165-74. 2007
  9. ncbi Protective effect of hepatocyte growth factor against degeneration of the retinal pigment epithelium and photoreceptor in sodium iodate-injected rats
    Kouji Ohtaka
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Curr Eye Res 31:347-55. 2006
  10. ncbi Functional changes in rod and cone pathways after photoreceptor loss in light-damaged rats
    Tomomi Takahashi
    Department of Ophthalmology, Iwate Medical University, School of Medicine, Morioka, Iwate, Japan
    Curr Eye Res 30:703-13. 2005

Collaborators

Detail Information

Publications36

  1. ncbi Macular function evaluated by focal macular electroretinograms after reduced fluence photodynamic therapy in eyes with polypoidal choroidal vasculopathy
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Doc Ophthalmol 124:91-8. 2012
    ..The macular function was retained after RFPDT without a transient decrease in visual function. Further study is needed to determine the long-term efficacy of RFPDT for eyes with PCV...
  2. ncbi Idiopathic choroidal neovascularization as an early manifestation of inflammatory chorioretinal diseases
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Retina 28:703-10. 2008
    ..We describe four patients with idiopathic choroidal neovascularization (ICNV) who developed inflammatory chorioretinal diseases in the ipsilateral or contralateral eye...
  3. ncbi Sensitivity and specificity of photopic negative response of focal electoretinogram to detect glaucomatous eyes
    S Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Br J Ophthalmol 94:202-8. 2010
    ..To determine the sensitivity and specificity of the photopic negative response (PhNR) of the focal electroretinograms (ERG; focal PhNR) to detect glaucomatous eyes with different degrees of visual field defects...
  4. ncbi Photopic negative response of focal electoretinograms in glaucomatous eyes
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 49:5636-44. 2008
    ..To determine the clinical importance of the photopic negative response (PhNR) of the focal electoretinogram (fERG) for diagnosing glaucoma...
  5. ncbi Correlation between photopic negative response and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes
    Shigeki Machida
    Department of Ophthalmology, School of Medicine, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate, Japan
    Invest Ophthalmol Vis Sci 49:2201-7. 2008
    ..To investigate whether there is a significant correlation between the photopic negative response (PhNR) of the electroretinogram (ERG) and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes...
  6. ncbi Melanoma-associated retinopathy associated with intranasal melanoma
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Uchimaru, Morioka, Japan
    Doc Ophthalmol 122:191-7. 2011
    ..To present a case of melanoma-associated retinopathy (MAR) associated with an intranasal melanoma...
  7. ncbi Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation
    Tomoharu Nishimura
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 52:7610-7. 2011
    ..To determine how the different stages of retinal processing change after photoreceptor degeneration in rabbits carrying the Pro347Leu rhodopsin mutation (Tg rabbits)...
  8. ncbi The Effect of intravitreal N-methyl-DL-aspartic acid on the electroretinogram in Royal College of surgeons rats
    Takayuki Ohzeki
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Jpn J Ophthalmol 51:165-74. 2007
    ..To investigate how the third-order neuronal response contributes to shaping the electroretinogram (ERG) in the Royal College of Surgeons (RCS) rat...
  9. ncbi Protective effect of hepatocyte growth factor against degeneration of the retinal pigment epithelium and photoreceptor in sodium iodate-injected rats
    Kouji Ohtaka
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Curr Eye Res 31:347-55. 2006
    ..This suggests that HGF could be used as a therapeutic agent for degeneration of photoreceptors as well as RPE...
  10. ncbi Functional changes in rod and cone pathways after photoreceptor loss in light-damaged rats
    Tomomi Takahashi
    Department of Ophthalmology, Iwate Medical University, School of Medicine, Morioka, Iwate, Japan
    Curr Eye Res 30:703-13. 2005
    ..The functional loss from the photoreceptor death had a greater effect on the cone pathway than on the rod pathway when the retinal function was assessed by the b-wave...
  11. ncbi Relationship between the s-wave amplitude of the multifocal electroretinogram and the retinal nerve fiber layer thickness in glaucomatous eyes
    Junfuku Nitta
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
    Jpn J Ophthalmol 49:481-90. 2005
    ....
  12. ncbi Correlation between photopic negative response of focal electroretinograms and local loss of retinal neurons in glaucoma
    Kunifusa Tamada
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka Iwate, Japan
    Curr Eye Res 35:155-64. 2010
    ..To determine the relationship between the photopic negative response of the focal electroretinogram and the structural parameters of the inner retina and optic nerve head in glaucoma...
  13. ncbi Pharmacological dissection of multifocal electroretinograms of rabbits with Pro347Leu rhodopsin mutation
    Daisuke Yokoyama
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Jpn J Ophthalmol 54:458-66. 2010
    ..To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons...
  14. ncbi Photopic negative response of full-field and focal macular electroretinograms in patients with optic nerve atrophy
    Kunifusa Tamada
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Jpn J Ophthalmol 53:608-14. 2009
    ..To determine alterations of the photopic negative response (PhNR) in the full-field and focal macular electroretinograms (ERGs) of patients with optic nerve atrophy (ONA)...
  15. ncbi Decrease of blue cone sensitivity in acute idiopathic blind spot enlargement syndrome
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Am J Ophthalmol 138:296-9. 2004
    ..To determine the sensitivity of the blue cone system by static perimetry in patients with unilateral acute idiopathic blind spot enlargement (AIBSE) syndrome...
  16. ncbi Choroidal circulatory disturbance in ocular sarcoidosis without the appearance of retinal lesions or loss of visual function
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
    Jpn J Ophthalmol 48:392-6. 2004
    ..We report a case of ocular sarcoidosis representing a choroidal circulatory disturbance without the appearance of retinal lesions or loss of retinal function...
  17. ncbi Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction
    Mineo Kondo
    Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    PLoS ONE 6:e19911. 2011
    ..The purpose of the current study is to investigate whether there are autoantibodies against TRPM1 in the sera of PR patients exhibiting ON bipolar cell dysfunction...
  18. ncbi High prevalence of myopia in Japanese patients with idiopathic focal subretinal neovascularization
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Retina 26:170-5. 2006
    ..To determine whether myopia is more prevalent in Japanese patients with idiopathic focal subretinal neovascularization (IFSN) than in normal control subjects...
  19. ncbi Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 49:442-52. 2008
    ....
  20. ncbi Predominant loss of the photopic negative response in central retinal artery occlusion
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University, School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Am J Ophthalmol 137:938-40. 2004
    ..To determine how the photopic negative response (PhNR) is affected in central retinal artery occlusion (CRAO)...
  21. ncbi Third-order neuronal responses contribute to shaping the negative electroretinogram in sodium iodate-treated rats
    Michiko Tanaka
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan
    Curr Eye Res 30:443-53. 2005
    ..The relative preservation of the third-order neuronal response plays a role in shaping the negative ERGs in this model...
  22. ncbi Punctate outer retinal toxoplasmosis with multiple choroidal neovascularizations
    Takamitsu Fujiwara
    Department of Ophthalmology, Iwate Medical University, School of Medicine, Morioka, Iwate, Japan
    Retina 26:360-2. 2006
  23. ncbi Neuroprotective effect of hepatocyte growth factor against photoreceptor degeneration in rats
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Invest Ophthalmol Vis Sci 45:4174-82. 2004
    ..To determine whether hepatocyte growth factor (HGF) has a neuroprotective effect against photoreceptor degeneration in rats...
  24. ncbi Changes of oscillatory potentials and photopic negative response in patients with early diabetic retinopathy
    Junya Kizawa
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Jpn J Ophthalmol 50:367-73. 2006
    ..The amplitudes and implicit times of the OPs are better indicators than those of the PhNR in detecting functional decreases in patients with early diabetic retinopathy...
  25. ncbi Mutton fat-like subretinal precipitates associated with Vogt-Koyanagi-Harada disease
    Kuniko Hamabata
    Department of Ophthalmology, Iwate Medical University, School of Medicine, Morioka 020 8505, Japan
    Ocul Immunol Inflamm 18:44-5. 2010
    ..To report a case of Vogt-Koyanagi-Harada (VKH) disease presenting mutton fat like subretinal precipitates...
  26. ncbi Selective loss of the photopic negative response in patients with optic nerve atrophy
    Yasutaka Gotoh
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Arch Ophthalmol 122:341-6. 2004
    ..879; P<.001). CONCLUSIONS: Selective reduction and loss of the PhNR amplitude was found in eyes with optic nerve atrophy, which suggests that the PhNR can be used to evaluate the function of ganglion cells or their axons...
  27. ncbi A case of herpetic epithelial keratitis after triamcinolone acetonide subtenon injection
    Kouhei Hashizume
    Department of Ophthalmology, Iwate Medical University, School of Medicine, Iwate, Japan
    Cornea 28:463-4. 2009
    ..We report a case of herpes simplex virus (HSV) epithelial keratitis that developed after a subtenon triamcinolone acetonide (TA) injection...
  28. ncbi Asymmetry of focal macular photopic negative responses (PhNRs) in monkeys
    Yukihide Kurimoto
    Department of Ophthalmology, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Exp Eye Res 88:92-8. 2009
    ..These results suggest that the upper-lower and nasal-temporal asymmetries of PhNR in the primate retina are mainly caused by TTX-sensitive spiking activities of inner retinal neurons...
  29. ncbi Correlation of retinal function with retinal histopathology following ischemia-reperfusion in rat eyes
    Yasuko Mukaida
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Curr Eye Res 28:381-9. 2004
    ..However, if one selects the stimulus intensity at the dip, the functional loss would be exaggerated in spite of the presence of cells in the INL...
  30. ncbi Vitreous levels of vascular endothelial growth factor in eyes with anterior hyaloidal fibrovascular proliferation
    Takaki Kobayashi
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Clin Ophthalmol 4:1043-6. 2010
    ..To determine the intravitreal levels of vascular endothelial growth factor (VEGF) in eyes with anterior hyaloidal fibrovascular proliferation (AHFVP)...
  31. ncbi Retinal ganglion cell function after repeated intravitreal injections of ranibizumab in patients with age-related macular degeneration
    Tomoharu Nishimura
    Department of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Clin Ophthalmol 6:1073-82. 2012
    ..The purpose of this study was to evaluate the safety of intravitreal ranibizumab injection in patients with age-related macular degeneration...
  32. ncbi Monozygotic twins with polypoidal choroidal vasuculopathy
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine
    Clin Ophthalmol 4:793-800. 2010
    ..To present the first findings in the set of monozygotic twins with polypoidal choroidopathy (PCV)...
  33. ncbi Observation of the ocular fundus by an infrared-sensitive video camera after vitreoretinal surgery assisted by indocyanine green
    Shigeki Machida
    Department of Ophthalmology, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Retina 23:183-91. 2003
    ..To investigate how long indocyanine green (ICG) dye remains in the ocular fundus and how the remaining dye interferes with ICG angiographic findings after vitreoretinal surgery assisted by ICG...
  34. ncbi Choroidal findings in idiopathic uveal effusion syndrome
    Tomomi Harada
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Clin Ophthalmol 5:1599-601. 2011
    ..We report choroidal findings by means of enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) in a patient with idiopathic uveal effusion syndrome (IUES)...
  35. ncbi Ophthalmoplegia associated with transorbital penetrating brainstem injury by broken fishing pole
    Aki Kaneko-Ohtaki
    Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan
    Clin Ophthalmol 5:927-9. 2011
    ..The eye position and eye movements fully recovered within 3 months. These findings suggest a good prognosis for this type of trauma unless life-threatening changes develop...
  36. ncbi Case of subretinal hemorrhage that developed from a prepapillary vascular loop
    Takamitsu Fujiwara
    Jpn J Ophthalmol 48:175-7. 2004