Takaaki Beppu

Summary

Affiliation: Iwate Medical University
Country: Japan

Publications

  1. doi request reprint Standardized uptake value in high uptake area on positron emission tomography with 18F-FRP170 as a hypoxic cell tracer correlates with intratumoral oxygen pressure in glioblastoma
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, 020 8505, Japan
    Mol Imaging Biol 16:127-35. 2014
  2. pmc Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol 259:1698-705. 2012
  3. doi request reprint Prediction of malignancy grading using computed tomography perfusion imaging in nonenhancing supratentorial gliomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurooncol 103:619-27. 2011
  4. ncbi request reprint Primary granulomatous angiitis of the central nervous system: findings of magnetic resonance spectroscopy and fractional anisotropy in diffusion tensor imaging prior to surgery. Case report
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurosurg 107:873-7. 2007
  5. ncbi request reprint Choice of posterior subtemporal transtentorial approach for tumor resection in deep anteromedial superior cerebellum
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 49:42-6. 2009
  6. ncbi request reprint Utility of three-dimensional anisotropy contrast magnetic resonance axonography for determining condition of the pyramidal tract in glioblastoma patients with hemiparesis
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1, Uchimaru, 020 8505 Morioka, Japan
    J Neurooncol 73:137-44. 2005
  7. doi request reprint Desmoplastic infantile astrocytoma and characteristics of the accompanying cyst. Case report
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurosurg Pediatr 1:148-51. 2008
  8. ncbi request reprint Fractional anisotropy value by diffusion tensor magnetic resonance imaging as a predictor of cell density and proliferation activity of glioblastomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medicl university, Morioka 020 8505, Japan
    Surg Neurol 63:56-61; discussion 61. 2005
  9. doi request reprint Assessment of damage to cerebral white matter fiber in the subacute phase after carbon monoxide poisoning using fractional anisotropy in diffusion tensor imaging
    Takaaki Beppu
    Departments of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, 020 8505, Japan
    Neuroradiology 52:735-43. 2010
  10. doi request reprint 1H-magnetic resonance spectroscopy indicates damage to cerebral white matter in the subacute phase after CO poisoning
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol Neurosurg Psychiatry 82:869-75. 2011

Collaborators

Detail Information

Publications36

  1. doi request reprint Standardized uptake value in high uptake area on positron emission tomography with 18F-FRP170 as a hypoxic cell tracer correlates with intratumoral oxygen pressure in glioblastoma
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, 020 8505, Japan
    Mol Imaging Biol 16:127-35. 2014
    ..The aim of this study was to clarify the reliability of positron emission tomography (PET) using a new hypoxic cell tracer, 1-(2-[(18)F]fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole ((18)F-FRP170)...
  2. pmc Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol 259:1698-705. 2012
    ..The present results suggest that FA in the centrum semiovale offers a quantitative indicator of the extent of demyelination in damaged CWM during the subacute phase in CO-poisoned patients...
  3. doi request reprint Prediction of malignancy grading using computed tomography perfusion imaging in nonenhancing supratentorial gliomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurooncol 103:619-27. 2011
    ..CTP offers a useful method for differentiating between G3 and G2 in nonenhancing gliomas...
  4. ncbi request reprint Primary granulomatous angiitis of the central nervous system: findings of magnetic resonance spectroscopy and fractional anisotropy in diffusion tensor imaging prior to surgery. Case report
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurosurg 107:873-7. 2007
    ..Although the low FA value in the present case enabled the authors to rule out a diagnosis of glioblastoma, FA values in inflammatory lesions require careful interpretation...
  5. ncbi request reprint Choice of posterior subtemporal transtentorial approach for tumor resection in deep anteromedial superior cerebellum
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 49:42-6. 2009
    ..Scrupulous evaluation using preoperative neuroimaging is crucial when deciding on the surgical approach...
  6. ncbi request reprint Utility of three-dimensional anisotropy contrast magnetic resonance axonography for determining condition of the pyramidal tract in glioblastoma patients with hemiparesis
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1, Uchimaru, 020 8505 Morioka, Japan
    J Neurooncol 73:137-44. 2005
    ..To estimate extent of pyramidal tract destruction, fractional anisotropy (FA) values using diffusion tensor magnetic resonance imaging were examined for both the responsible and non-pathological pyramidal tracts...
  7. doi request reprint Desmoplastic infantile astrocytoma and characteristics of the accompanying cyst. Case report
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurosurg Pediatr 1:148-51. 2008
    ....
  8. ncbi request reprint Fractional anisotropy value by diffusion tensor magnetic resonance imaging as a predictor of cell density and proliferation activity of glioblastomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medicl university, Morioka 020 8505, Japan
    Surg Neurol 63:56-61; discussion 61. 2005
    ....
  9. doi request reprint Assessment of damage to cerebral white matter fiber in the subacute phase after carbon monoxide poisoning using fractional anisotropy in diffusion tensor imaging
    Takaaki Beppu
    Departments of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, 020 8505, Japan
    Neuroradiology 52:735-43. 2010
    ..We examined whether diffusion tensor imaging can sensitively represent damage to fibers of the centrum semiovale in the subacute phase after CO intoxication...
  10. doi request reprint 1H-magnetic resonance spectroscopy indicates damage to cerebral white matter in the subacute phase after CO poisoning
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka 020 8505, Japan
    J Neurol Neurosurg Psychiatry 82:869-75. 2011
    ..The authors examined whether (1)H-magnetic resonance spectroscopy (MRS) can identify damage to the centrum semiovale in the subacute phase after CO exposure...
  11. ncbi request reprint Measurement of fractional anisotropy using diffusion tensor MRI in supratentorial astrocytic tumors
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurooncol 63:109-16. 2003
    ..Measurement of FA value using DTI will allow prediction of histological characteristics such as cellularity, vascularity and/or fiber structure in astrocytic tumors...
  12. ncbi request reprint Change of oxygen pressure in glioblastoma tissue under various conditions
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurooncol 58:47-52. 2002
    ..It is possible that the pO2 level in peritumoral tissue is affected by intracranial pressure, whereas that in the intratumoral tissue is usually low. HBO was the optimal procedure for oxygenation, but its benefit was reduced over time...
  13. ncbi request reprint A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurooncol 61:161-70. 2003
    ....
  14. ncbi request reprint Proton magnetic resonance spectroscopy and diffusion-weighted imaging of tumefactive demyelinating plaque
    Kazuki Masu
    Department of Neurosurgery, Iwate Medical University, Morioka, Iwate
    Neurol Med Chir (Tokyo) 49:430-3. 2009
    ....
  15. ncbi request reprint Three-dimensional anisotropy contrast imaging of pontine gliomas: 2 case reports
    Hiroshi Kashimura
    Department of Neurosurgery, Iwate Medical University School of Medicine, Morioka, Iwate 020 8505, Japan
    Surg Neurol 67:156-9; discussion 159. 2007
    ..We describe 2 cases of pontine gliomas who did not present with motor and sensory disturbance...
  16. ncbi request reprint Preoperative imaging of superficially located glioma resection using short inversion-time inversion recovery images in high-field magnetic resonance imaging
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimau, Morioka 020 8505, Japan
    Clin Neurol Neurosurg 109:327-34. 2007
    ..The aim of the present study is to evaluate the effectiveness of STIR in imaging tumor involvement of the cortical surface and intra-axial structures, its usefulness in the resection of superficially located gliomas...
  17. doi request reprint Detecting damaged regions of cerebral white matter in the subacute phase after carbon monoxide poisoning using voxel-based analysis with diffusion tensor imaging
    Shunrou Fujiwara
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    Neuroradiology 54:681-9. 2012
    ....
  18. ncbi request reprint Diffusion tensor imaging for preoperative evaluation of tumor grade in gliomas
    Takashi Inoue
    Department of Neurosurgery, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Clin Neurol Neurosurg 107:174-80. 2005
    ..0002). The MD values were not correlated with the other grades of glioma. FA values can distinguish between high grade and low grade gliomas. This is useful in deciding the surgical strategy or selecting the site of stereotactic biopsy...
  19. ncbi request reprint Changes in cognitive function after carotid endarterectomy in older patients: comparison with younger patients
    Yoshihiro Takahashi
    Department of Neurosurgery, Iwate Medical University, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 53:353-9. 2013
    ....
  20. ncbi request reprint Fusion of magnetic resonance angiography and magnetic resonance imaging for surgical planning for meningioma--technical note
    Hiroshi Kashimura
    Department of Neurosurgery, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 48:418-21; discussion 422. 2008
    ..Fusion of MR angiography and MR imaging can clarify relationships between the intracranial vasculature and meningioma, and may be helpful for surgical planning for meningioma...
  21. ncbi request reprint Ganglioneurocytoma: distinctive variant of central neurocytoma
    Akira Kurose
    Department of Pathology, Iwate Medical University School of Medicine, Morioka, Japan
    Pathol Int 57:799-803. 2007
    ....
  22. ncbi request reprint Use of fractional anisotropy value by diffusion tensor MRI for preoperative diagnosis of astrocytic tumors: case report
    Toshinari Misaki
    Department of Neurosurgery, Iwate Medical University, Morioka, Japan
    J Neurooncol 70:343-8. 2004
    ..In this report, we discuss the relationship between FA and other characteristics of the present tumor, and discuss the utility of FA measurement in astrocytic tumors...
  23. pmc Detection of misery perfusion in the cerebral hemisphere with chronic unilateral major cerebral artery steno-occlusive disease using crossed cerebellar hypoperfusion: comparison of brain SPECT and PET imaging
    Yoshiyasu Matsumoto
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka, 020 8505, Japan
    Eur J Nucl Med Mol Imaging 40:1573-81. 2013
    ....
  24. ncbi request reprint Diffusion tensor imaging for differentiation of recurrent brain tumor and radiation necrosis after radiotherapy--three case reports
    Hiroshi Kashimura
    Department of Neurosurgery, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate, Japan
    Clin Neurol Neurosurg 109:106-10. 2007
    ..The assessment of FA value in enhanced lesions after radiotherapy may be able to differentiate radiation necrosis from tumor recurrence...
  25. ncbi request reprint Lipomatous meningioma with concomitant acute subdural hematoma--case report--
    Hiroshi Kashimura
    Department of Neurosurgery, Iwate Medical University School of Medicine, Morioka, Iwate, Japan
    Neurol Med Chir (Tokyo) 48:466-9. 2008
    ..Longstanding intratumoral congestion probably caused hyaline deposition in the tissue, leading to vessel rupture...
  26. ncbi request reprint [Utility of hyperbaric oxygenation in radiotherapy for malignant brain tumors--a literature review]
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Brain Nerve 61:677-81. 2009
    ..We reviewed the literature to evaluate the manner in which HBO therapy contributes to clinical fields in cases of RT administration for malignant brain tumors...
  27. ncbi request reprint Three-dimensional anisotropy contrast imaging of gliomatosis cerebri: two case reports
    Takashi Inoue
    Department of Neurosurgery, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Surg Neurol 62:151-4; discussion 154-5. 2004
    ..Magnetic resonance imaging (MRI) can provide a preoperative diagnosis of gliomatosis cerebri, but the findings sometimes do not correspond with the clinical symptoms or histologic findings...
  28. ncbi request reprint Detection of gene amplification and deletion in high-grade gliomas using a genome DNA microarray (GenoSensor Array 300)
    Teruo Sasaki
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    Brain Tumor Pathol 20:59-63. 2003
    ..We conclude that the GenoSensor Array 300 genomic DNA microarray is a useful method for the comprehensive identification of amplified and deleted genes in glioblastoma...
  29. ncbi request reprint [Granulomatous change of the pituitary stalk caused by Rathke's cleft cyst: a case report]
    Nobukazu Komoribayashi
    Department of Neurosurgery, Iwate Medical University School of Medicine, 19 1 Uchimaru, Morioka, Iwate 020 8505, Japan
    No Shinkei Geka 31:1193-6. 2003
    ..In the literature, diabetes inspidus was not improved by surgical procedures. However, we suggest that the mass should be totally resected, because some cases in literature showed visual disturbance or hypo-pituitarism under observation...
  30. doi request reprint Treatment outcomes in glioblastoma patients aged 76 years or older: a multicenter retrospective cohort study
    Takeo Uzuka
    Department of Neurosurgery, Niigata Cancer Center Hospital, 2 15 3 Kawagishi chou, Chuo Ku, Niigata, 951 8566, Japan
    J Neurooncol 116:299-306. 2014
    ..25-0.784, p < 0.001).The findings of this study suggest that postoperative KPS score is an important prognostic factor for glioblastoma patients aged ≥ 76 years, and that these patients may benefit from temozolomide therapy...
  31. ncbi request reprint Alleviation of intracranial air using carbon dioxide gas during intraventricular tumor resection
    Takaaki Beppu
    Department of Neurosurgery, Iwate Medical University, Morioka 020 8505, Japan
    Clin Neurol Neurosurg 108:655-60. 2006
    ..The aim of the present study was to elucidate whether intracranial air after intraventricular surgery could be alleviated safely using CO2, and investigate its clinical usefulness...
  32. ncbi request reprint Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma
    Li Hua Pan
    First Department of Pathology, Iwate Medical University School of Medicine, Morioka, Japan
    Neurol Res 24:677-83. 2002
    ..These findings suggest that CTGF may have the potential to stimulate angiogenesis in glioblastoma and function as an angiogenic factor in the process of tumor growth...
  33. doi request reprint Association of stem cell marker CD133 expression with dissemination of glioblastomas
    Atsushi Sato
    Department of Neurosurgery, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
    Neurosurg Rev 33:175-83; discussion 183-4. 2010
    ..58). The results suggest that CD133 could be a molecular predictor of glioblastoma dissemination, and also give rise to an intriguing idea that CD133-positive cancer stem cells may be implicated in the initiation of disseminated lesions...
  34. ncbi request reprint [A case of multiple cerebral infarction accompanied by a cor triatriatum]
    Hideaki Nishimoto
    Department of Neurosurgery, Iwate Medical University, Uchimaru 19 1, Morioka, Iwate 020 8505, Japan
    No Shinkei Geka 32:257-60. 2004
    ..We suspect that her multiple infarctions were caused by embolism due to a cor triatriatum. Here, we discuss the relationship between her embolic stroke and the cor triatriatum, with references to literature on the subject...
  35. ncbi request reprint [A case of malignant peripheral nerve sheath tumor originating from the cervical vagus nerve]
    Yasutaka Kuzu
    Department of Neurosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka 020 8505, Japan
    No Shinkei Geka 30:523-6. 2002
    ....
  36. ncbi request reprint Spontaneous Recovery of Reduced Cortical Central Benzodiazepine Receptor Binding Potential on I-123 Iomazenil SPECT in a Patient With Status Epilepticus
    Hiroki Kuroda
    From the Department of Neurosurgery and Cyclotron Research Center, Iwate Medical University, Morioka, Japan
    Clin Nucl Med 35:126-7. 2010
    ..However, 3 months later, repeat studies showed resolution of the reduction in cortical benzodiazepine receptor binding potential, resolution of hyperperfusion, and resolution of crossed cerebellar hypoperfusion...