Masaharu Ishihara

..Several modalities have been developed and primary percutaneous intervention with stent is the current preferred strategy for patients with AMI...

..However, the optimal management goal of glucose levels for patients with acute hyperglycemia remains uncertain. Further studies are warranted into the appropriate management in patients with AMI and acute hyperglycemia...

..Progress in management of acute myocardial infarction (AMI) might have changed the effect of gender on mortality...

..In conclusion, optimal glucose level on admission may be different between diabetic and nondiabetic patients with AMI...

..Admission hyperglycemia and diabetes should be treated as 2 distinct disease states...

..This study was undertaken to assess the relationship between acute hyperglycemia and left ventricular function after reperfusion therapy for acute myocardial infarction (AMI)...

..These findings suggested that a simple combination of WBC count and PG level might provide further information for predicting outcomes in patients with AMI...

..Patients with new diabetes have poor outcomes, despite their lower HbA1c levels...

..We also assessed outcome of patients with a history of diabetes mellitus in the PCI era...

..Recent experiments have reported that the beneficial effect of ischemic preconditioning are reversed in the aged heart...

..Recent experimental studies have reported that preconditioning has anti-inflammatory effect...

..To assess the influence of diabetes on long term prognosis after reperfusion treatment and its interaction with multivessel disease...

..This study was undertaken to assess whether prodromal angina could have beneficial effects in diabetic patients with acute myocardial infarction (AMI)...

..2% and 5.5%, respectively; p=0.002). Stenting is now the most frequently chosen treatment for AMI and sustained TIMI grade 3 flow is obtained in most of the cases, with the result that mortality has reduced by 50% in the past decade...

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..To investigate whether admission hyperglycaemia in non-diabetic patients with acute myocardial infarction (AMI) is a surrogate for previously undiagnosed abnormal glucose tolerance...

..These findings suggest that prodromal angina might favorably alter the relation between time to reperfusion and outcomes after AMI. However, prodromal angina did not afford any benefits if reperfusion was not achieved...

..Serum UA level is a suitable marker for predicting AMI-related future adverse events, and the combination of Killip's class and serum UA level after AMI is a good predictor of mortality in patients who have AMI...

..Follow-up echocardiography 9 days later showed mild hypokinesia of the anterior wall with an ejection fraction of 77%. He was discharged with no neurologic complications 18 days later...

..Previous studies in the prethrombolytic or thrombolytic era have reported that right bundle-branch block (RBBB) is associated with poor clinical outcome in patients with acute myocardial infarction (AMI)...

..It remains unclear whether spontaneous anterograde flow preserves myocardial fatty acid metabolism in patients with acute myocardial infarction (AMI)...

..The purpose of this study was to assess the usefulness of electrocardiogram on admission to predict short-term prognosis in patients with acute myocardial infarction (AMI) associated with left main coronary artery (LMCA)...

..We investigated a potential explanation for the association between acute hyperglycemia and adverse outcomes after acute myocardial infarction...

..8% vs 15.9%, p = 0.04). CONCLUSION: These findings suggest that lack of microvascular reperfusion following revascularization may be one of the mechanisms of a poor clinical outcome in diabetic patients with AMI...

..Electrocardiologists should recognize atrioventricular crosstalk during a stimulation threshold test to avoid repositioning the atrial lead unnecessarily or inducing ventricular arrhythmia...

..The time course of the electrocardiographic (ECG) changes in patients with tako-tsubo syndrome remains unknown...

..09, 95% confidence interval 0.53 to 2.24). In conclusion, female gender was associated with in-hospital mortality after acute myocardial infarction in patients ≥ 70 years old but not in patients < 70 years old...

..Because atrioventricular block recurred or persisted even after the resolution of takotsubo cardiomyopathy, the patients received permanent pacemakers...

..In patients with diabetes mellitus, collateral circulation, but not prodromal angina pectoris, was associated with higher predischarge LVEF...

..The long-term safety and efficacy of drug-eluting stents for patients with acute myocardial infarction (AMI) remain controversial...

..He was treated with aspiration thrombectomy...

..This study was undertaken to assess the neointimal coverage and thrombus formation after SES implantation between patients with STEMI and those with stable angina pectoris (SAP)...

..Follow-up cardiac catheterization after 16 days showed normal wall motion with no pressure gradients. However, dobutamine stress (10 microg/kg/min) caused a pressure gradient of 60 mmHg between the left ventricular apex and the aorta...

..However, it is probable that patients with tako-tsubo cardiomyopathy have an incidental CAD because most patients are elderly. We assessed the prevalence of incidental CAD...

..To investigate the impact of a history of diabetes mellitus on the neurologic outcome in comatose survivors of cardiac arrest of cardiac origin treated with mild hypothermia...

..54; follow-up: 86+/-22 ml/m(2) vs 83+/-18 ml/m(2), p=0.60). These data suggest that IABP enhances the improvement in LVEF independent of remodeling in AMI patients with persistent ST elevation after revascularization...

..The data suggest that coronary stenting did not influence microvascular circulation (improvement or detriment) in patients with reperfused AMI...

..They had persistent left ventricular dysfunction even during their convalescence...

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..The current case implies that a Brugada-type ST-segment elevation, which is thought to be false in acute pericarditis, may be true in some patients with asymptomatic Brugada syndrome...

..Intravascular ultrasound revealed an atherosclerotic plaque in the segment immediately proximal to the myocardial bridging, but did not reveal any plaque within or distal to the site. He was discharged 12 days later...

..Recent studies have demonstrated that stress-induced Tako-tsubo cardiomyopathy is likely to occur in elderly female patients...

..This study was undertaken to investigate the effect of prodromal AP on infarct progression after the onset of acute myocardial infarction (AMI)...

..We assessed angioscopic findings after everolimus-eluting stents (EES) implantation, compared with sirolimus-eluting stents (SES)...

..In the percutaneous coronary intervention (PCI) era, the impact of initial ST-segment elevation magnitude on left ventricular (LV) function in patients with acute myocardial infarction (AMI) remains unclear...

..Four months after the operation, a solid thrombus (48x30 mm) appeared again at the same site despite anticoagulant treatment. The patient died of both left and right heart failure 33 months after the operation...

..Even after stoppage of 25 h overdride pacing, it never recurred. Temporary overdrive pacing is an easy and feasible therapy for a drug-resistant electrical storm associated with AMI and should be performed in the early stage...

..This study compared the outcomes of IHCA and out-of-hospital cardiac arrest (OHCA) patients treated with ECLS...

..The serum lipoprotein (a) [Lp(a)] level is genetically determined and remains consistent during a person's life. Previous cohort studies have reported that subjects with a high Lp(a) level are at high risk of cardiac events...

..In conclusion, cardiologists should recognize that takotsubo cardiomyopathy can occur even after successful resuscitation of cardiac arrest. Early diagnosis and appropriate intensive care are essential in these critically ill patients...

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..10, p=0.04). CONCLUSIONS: Our data demonstrated that absence of persistent ischemic chest pain appears to be a simple and reliable marker which predicts left ventricular dilation after late reperfused AMI...

..Intravenous bolus administration of nicorandil was consistently effective to relieve his symptoms. Anginal attack was finally prevented by massive oral nicorandil in addition to conventional treatment...

..Her clinical course suggested that the transient cerebral ischemic attack was caused by embolism of the left ventricular thrombus associated with 'tako-tsubo-like left ventricular dysfunction'...

..The purpose of this study was to evaluate the effect of aortic valve replacement on electrocardiogram (ECG) in patients with aortic valve stenosis...

..Follow-up transthoracic echocardiography 13 days later showed normal left ventricular wall motion with no pressure gradient through the left ventricular outflow tract...

..CONCLUSIONS: Tako-tsubo cardiomyopathy can occur despite treatment with calcium channel blockers, nitrates or beta-blockers, suggesting limitation of these medications to prevent tako-tsubo cardiomyopathy...

..Careful follow-up is required to be sure that the system continues to function according to its design specifications...

..quot; Our aim was to evaluate its clinical features and causes...

..In conclusion, therapeutic hypothermia with a temperature of 34.0 degrees C can be used safely in Brugada syndrome...

..The results indicated a considerable improvement in DSA image quality; thus, the coronary arteries, carotid artery, and vein were clearly enhanced...

..20-10.6; p = 0.04) and elderly patients (odds ratio 3.04; 95%CI 1.06-18.1; p = 0.04). CONCLUSIONS: Angina within the 24 h before AMI is associated with better in-hospital outcomes in elderly and nonelderly patients...

..However, the relationship between WBC count and prognosis after AMI has not been investigated since coronary intervention was introduced...

..CONCLUSIONS: In-patients undergoing PCI for AMI, admission hyperglycemia, irrespective of the presence or absence of diabetes, is associated with increased in-hospital mortality, whereas diabetes without admission hyperglycemia is not...

..However, it is unclear whether the same is true in Japan, which has a different healthcare system...

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..The impact of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) remains unclear...

..Beneficial effects of preinfarction angina on infarct size and in-hospital outcome are evident in patients with anterior infarction, but not in those with nonanterior infarction...

..We diagnosed her as having tako-tsubo cardiomyopathy. She was discharged well 10 days later...

..ST-segment elevation was obvious in leads V1-3 rather than in leads V4-6. Because ST-segment elevation is absent in left precordial leads, cardiologists should take care not to fail to diagnose variant form of tako-tsubo cardiomyopathy...

..She was diagnosed as having tako-tsubo cardiomyopathy. Follow-up left ventriculography showed marked improvement of the left ventricular function (ejection fraction=74%) during only 41 h. She was discharged 3 days later...

..Patients who have acute myocardial infarction remain at major risk of cardiovascular events. We aimed to assess the effects of either human atrial natriuretic peptide or nicorandil on infarct size and cardiovascular outcome...

..We designed and investigated the efficacy of a novel percutaneous catheter therapy, rotational bidirectional thrombectomy (ROBOT), for PE...

..Clinicians should recognize that tako-tsubo cardiomyopathy is one of etiologies of chest symptom after automobile accident. It can occur due to emotional stress even if patients have no external injury...