A Oohira

Summary

Affiliation: Institute for Developmental Research
Country: Japan

Publications

  1. ncbi request reprint Effects of lipid-derivatized glycosaminoglycans (GAGs), a novel probe for functional analyses of GAGs, on cell-to-substratum adhesion and neurite elongation in primary cultures of fetal rat hippocampal neurons
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Kasugai, Aichi, Japan
    Arch Biochem Biophys 378:78-83. 2000
  2. ncbi request reprint Molecular interactions of neural chondroitin sulfate proteoglycans in the brain development
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi, 480 0392, Japan
    Arch Biochem Biophys 374:24-34. 2000
  3. ncbi request reprint Developmentally regulated expression of a brain specific species of chondroitin sulfate proteoglycan, neurocan, identified with a monoclonal antibody IG2 in the rat cerebrum
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi, Japan
    Neuroscience 60:145-57. 1994
  4. ncbi request reprint Occurrence of a N-terminal proteolytic fragment of neurocan, not a C-terminal half, in a perineuronal net in the adult rat cerebrum
    F Matsui
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    Brain Res 790:45-51. 1998
  5. ncbi request reprint Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incision
    F Matsui
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    Neuroscience 112:773-81. 2002
  6. ncbi request reprint Genomic organization and expression pattern of mouse neuroglycan C in the cerebellar development
    S Aono
    Departments of Perinatology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi 480 0392, Japan
    J Biol Chem 275:337-42. 2000
  7. ncbi request reprint Regulation of neuregulin expression in the injured rat brain and cultured astrocytes
    Y Tokita
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    J Neurosci 21:1257-64. 2001
  8. ncbi request reprint Two types of brain chondroitin sulfate proteoglycan: their distribution and possible functions in the rat embryo
    R Katoh-Semba
    Department of Perinatology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Japan
    Neurosci Res 31:273-82. 1998
  9. ncbi request reprint Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module
    Y Yasuda
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi, Japan
    Neurosci Res 32:313-22. 1998
  10. ncbi request reprint Neuroglycan C, a novel membrane-spanning chondroitin sulfate proteoglycan that is restricted to the brain
    E Watanabe
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi, Japan
    J Biol Chem 270:26876-82. 1995

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Effects of lipid-derivatized glycosaminoglycans (GAGs), a novel probe for functional analyses of GAGs, on cell-to-substratum adhesion and neurite elongation in primary cultures of fetal rat hippocampal neurons
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Kasugai, Aichi, Japan
    Arch Biochem Biophys 378:78-83. 2000
    ..These findings suggest that GAGs serve as a modulator for neurite elongation during neuronal network formation in the developing central nervous system...
  2. ncbi request reprint Molecular interactions of neural chondroitin sulfate proteoglycans in the brain development
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi, 480 0392, Japan
    Arch Biochem Biophys 374:24-34. 2000
    ..In addition, this review briefly covers potential functions of other neural chondroitin sulfate proteoglycans such as decorin, testican, NG2 proteoglycan, and amyloid precursor protein (APP) in developing and injured brains...
  3. ncbi request reprint Developmentally regulated expression of a brain specific species of chondroitin sulfate proteoglycan, neurocan, identified with a monoclonal antibody IG2 in the rat cerebrum
    A Oohira
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi, Japan
    Neuroscience 60:145-57. 1994
    ....
  4. ncbi request reprint Occurrence of a N-terminal proteolytic fragment of neurocan, not a C-terminal half, in a perineuronal net in the adult rat cerebrum
    F Matsui
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    Brain Res 790:45-51. 1998
    ..The presence of neurocan-130 in a limited number of glial cells may reflect some functional heterogeneity of the glia...
  5. ncbi request reprint Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incision
    F Matsui
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    Neuroscience 112:773-81. 2002
    ....
  6. ncbi request reprint Genomic organization and expression pattern of mouse neuroglycan C in the cerebellar development
    S Aono
    Departments of Perinatology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi 480 0392, Japan
    J Biol Chem 275:337-42. 2000
    ..This finding suggests the involvement of NGC in the differential adhesion and synaptogenesis of the climbing and parallel fibers with the Purkinje cell dendrites...
  7. ncbi request reprint Regulation of neuregulin expression in the injured rat brain and cultured astrocytes
    Y Tokita
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi 480 0392, Japan
    J Neurosci 21:1257-64. 2001
    ..The neuregulin expressed on reactive astrocytes may stimulate their proliferation and support the survival of neurons surrounding cortical brain wounds in vivo...
  8. ncbi request reprint Two types of brain chondroitin sulfate proteoglycan: their distribution and possible functions in the rat embryo
    R Katoh-Semba
    Department of Perinatology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Japan
    Neurosci Res 31:273-82. 1998
    ..No immunostaining with monoclonal antibody 6B4 was observed in cells that had incorporated bromodeoxyuridine in vivo. Possible functions of 6B4 proteoglycan in the rat embryo are discussed...
  9. ncbi request reprint Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module
    Y Yasuda
    Department of Perinatology, Institute for Developmental Research, Kasugai, Aichi, Japan
    Neurosci Res 32:313-22. 1998
    ..3 band, where the Sotos syndrome has been mapped. Involvement of the NGC gene in the etiology of the Sotos syndrome remains to be examined...
  10. ncbi request reprint Neuroglycan C, a novel membrane-spanning chondroitin sulfate proteoglycan that is restricted to the brain
    E Watanabe
    Department of Perinatology and Neuroglycoscience, Institute for Developmental Research, Aichi, Japan
    J Biol Chem 270:26876-82. 1995
    ..The sequence of the proteoglycan did not exhibit significant homology to any other known protein, indicating that the proteoglycan, designated neuroglycan C, is a novel integral membrane proteoglycan...
  11. ncbi request reprint Biochemical comparison of brain glycosaminoglycans between normal and reeler mutant mice
    F Matsui
    Department of Perinatology, Institute for Developmental Research, Aichi, Japan
    Neurosci Res 16:287-92. 1993
    ..The rate of synthesis and/or degradation of brain GAGs may be affected in the mutant mouse brain...
  12. ncbi request reprint Neuroglycan C, a neural tissue-specific transmembrane chondroitin sulfate proteoglycan, in retinal neural network formation
    M Inatani
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Tenri Hospital, Osaka, Japan
    Invest Ophthalmol Vis Sci 41:4338-46. 2000
    ..In the current study the expression pattern and characterization of NGC during the development of the retina were investigated...
  13. ncbi request reprint Expression of brain specific chondroitin sulfate proteoglycans, neurocan and phosphacan, in the developing and adult hippocampus of Ihara's epileptic rats
    S Kurazono
    Faculty of Health Sciences, Okayama University Medical School, 5-1 Shikatacho, 700-8558, Okayama, Japan
    Brain Res 898:36-48. 2001
    ....
  14. ncbi request reprint Inhibitory effects of neurocan and phosphacan on neurite outgrowth from retinal ganglion cells in culture
    M Inatani
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Japan
    Invest Ophthalmol Vis Sci 42:1930-8. 2001
    ....
  15. ncbi request reprint Upregulated expression of N-syndecan, a transmembrane heparan sulfate proteoglycan, in differentiated neural stem cells
    M Inatani
    Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Brain Res 920:217-21. 2001
    ..Our data indicate that N-syndecan may be involved in the differentiation of neural stem cells...
  16. ncbi request reprint Neuronal expression of the chondroitin sulfate proteoglycans receptor-type protein-tyrosine phosphatase beta and phosphacan
    N Hayashi
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Neuroscience 131:331-48. 2005
    ....
  17. ncbi request reprint Construction of perineuronal net-like structure by cortical neurons in culture
    S Miyata
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Neuroscience 136:95-104. 2005
    ..These results indicate that cultured cortical neurons are able to construct perineuronal net-like structure without glial cells...
  18. ncbi request reprint Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice
    K Ohyama
    Department of Anatomy, Keio University, School of Medicine, Tokyo 160, Japan
    Brain Res Dev Brain Res 107:219-26. 1998
    ..These results suggest that the heterophilic interaction between 6B4 proteoglycan on the neurons and L1 on the fibers is involved in the lateral migration of mesencephalic DA neurons in mice...