Koichi Kato

Summary

Affiliation: Institute for Molecular Science
Country: Japan

Publications

  1. Satoh T, Kato K. Structural Aspects of ER Glycoprotein Quality-Control System Mediated by Glucose Tagging. Adv Exp Med Biol. 2018;1104:149-169 pubmed publisher
  2. Morita K, Yamamoto Y, Hori A, Obata T, Uno Y, Shinohara K, et al. Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus Chaetomium thermophilum. Int J Mol Sci. 2018;19: pubmed publisher
    ..Finally, we have shown the transfer of actin from CtPFD to CtCCT. The study of the folding pathway formed by CtPFD and CtCCT should provide important information on mechanisms of the eukaryotic prefoldin⁻chaperonin system. ..
  3. Satoh T, Yamaguchi T, Kato K. Emerging structural insights into glycoprotein quality control coupled with N-glycan processing in the endoplasmic reticulum. Molecules. 2015;20:2475-91 pubmed publisher
    ..These complementary views provide new insights into glycoprotein recognition in quality control coupled with N-glycan processing. ..
  4. Inagaki K, Satoh T, Yagi Utsumi M, Le Gulluche A, Anzai T, Uekusa Y, et al. Redox-coupled structural changes of the catalytic a' domain of protein disulfide isomerase. FEBS Lett. 2015;589:2690-4 pubmed publisher
    ..Based on these findings, we propose that this conformational transition triggers the domain segregation coupled with the exposure of the hydrophobic surface. ..
  5. Sikdar A, Satoh T, Kawasaki M, Kato K. Crystal structure of archaeal homolog of proteasome-assembly chaperone PbaA. Biochem Biophys Res Commun. 2014;453:493-7 pubmed publisher
    ..These findings offer deeper insights into the molecular evolution relationships between the proteasome-assembly chaperones and the proteasome activators. ..
  6. Satoh T, Sumiyoshi A, Yagi Utsumi M, Sakata E, Sasakawa H, Kurimoto E, et al. Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activity. FEBS Lett. 2014;588:4422-30 pubmed publisher
    ..Our results help to elucidate how the substrate is recognized by the Josephin domain and properly positioned for an endo-type deubiquitination reaction. ..
  7. Kato K, Yamaguchi T. Paramagnetic NMR probes for characterization of the dynamic conformations and interactions of oligosaccharides. Glycoconj J. 2015;32:505-13 pubmed publisher
    ..These techniques can be applied to the characterization of transient, non-stoichiometric interactions and will contribute to the visualization of dynamic biomolecular processes involving sugar chains. ..
  8. Kicuntod J, Sangpheak K, Mueller M, Wolschann P, Viernstein H, Yanaka S, et al. Theoretical and Experimental Studies on Inclusion Complexes of Pinostrobin and β-Cyclodextrins. Sci Pharm. 2018;86: pubmed publisher
    ..Both PNS and its complexes significantly exerted a lowering effect on the IL-6 secretion in LPS-stimulated macrophages and showed a moderate cytotoxic effect against MCF-7 and HeLa cancer cell lines in vitro. ..
  9. Satoh T, Toshimori T, Noda M, Uchiyama S, Kato K. Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control. Protein Sci. 2016;25:2095-2101 pubmed publisher
    ..Here, we determined the structure of a complex formed between GIIα and the GIIα-binding domain of GIIβ, thereby providing a structural basis underlying the functional extension of this unique GH31 enzyme. ..

More Information

Publications19

  1. Yanaka S, Yagi H, Yogo R, Yagi Utsumi M, Kato K. Stable isotope labeling approaches for NMR characterization of glycoproteins using eukaryotic expression systems. J Biomol NMR. 2018;71:193-202 pubmed publisher
    ..Perspectives regarding the development of techniques for tailoring glycoform designs and isotope labeling of recombinant glycoproteins are also discussed. ..
  2. Cheng X, Yang B, Liu G, Olofsson T, Li H, Yanaka S, et al. A Total Bounded Variation Approach to Low Visibility Estimation on Expressways. Sensors (Basel). 2018;18: pubmed publisher
    ..Besides, the big video data are collected from the Tongqi expressway, Jiangsu, China. A total of 1,782,000 frames were used and the relative errors of the approach proposed are less than 10%. ..
  3. Kitazawa S, Yagi Utsumi M, Kato K, Kitahara R. Interactions Controlling the Slow Dynamic Conformational Motions of Ubiquitin. Molecules. 2017;22: pubmed publisher
    ..Identifying the interactions controlling specific motions of a protein will facilitate molecular design to achieve functional dynamics beyond native state dynamics. ..
  4. Kato K, Satoh T. Structural insights on the dynamics of proteasome formation. Biophys Rev. 2018;10:597-604 pubmed publisher
    ..This knowledge, in turn, provides a guiding principle in designing molecular machineries using protein engineering approaches and de novo synthesis of artificial molecular systems. ..
  5. Yagi H, Yan G, Suzuki T, Tsuge S, Yamaguchi T, Kato K. Lewis X-Carrying Neoglycolipids Evoke Selective Apoptosis in Neural Stem Cells. Neurochem Res. 2018;43:212-218 pubmed publisher
    ..This serendipitous finding may offer a new strategy for controlling neural cell fates using artificial glycoclusters. ..
  6. Takagi K, Saeki Y, Yashiroda H, Yagi H, Kaiho A, Murata S, et al. Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome ?-ring formation. Biochem Biophys Res Commun. 2014;450:1110-4 pubmed publisher
    ..Furthermore, our structure-guided mutational data demonstrate that the Pba3-Pba4 heterodimer acts as molecular matchmaker reinforcing the interaction between ?4 and ?5, which is the crucial step in the ?-ring formation. ..
  7. Yanaka S, Yamazaki T, Yogo R, Noda M, Uchiyama S, Yagi H, et al. NMR Detection of Semi-Specific Antibody Interactions in Serum Environments. Molecules. 2017;22: pubmed publisher
  8. Satoh T, Song C, Zhu T, Toshimori T, Murata K, Hayashi Y, et al. Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT. Sci Rep. 2017;7:12142 pubmed publisher
  9. Satoh T, Saeki Y, Hiromoto T, Wang Y, Uekusa Y, Yagi H, et al. Structural basis for proteasome formation controlled by an assembly chaperone nas2. Structure. 2014;22:731-43 pubmed publisher
    ..Thus, Nas2 operates as a proteasome activation blocker, offering a checkpoint during the formation of the 19S ATPase prior to its docking onto the proteolytic 20S core particle. ..
  10. Yagi H, Kato K. Functional roles of glycoconjugates in the maintenance of stemness and differentiation process of neural stem cells. Glycoconj J. 2017;34:757-763 pubmed publisher
    ..In this review, we outline current knowledge of the possible functional mechanisms of glycoconjugates to determine cell fates, which are associated with their expression pattern and structural characteristic features. ..