Tetsuya Yamamoto

Summary

Affiliation: Hyogo College of Medicine
Country: Japan

Publications

  1. ncbi request reprint 21-hydroxylase deficiency associated with male infertility: report of 2 cases with gene analyses
    Chihiro Sumida
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Japan
    Intern Med 50:1317-21. 2011
  2. pmc Abnormal haemoglobins, Hb Takamatsu and Hb G-Szuhu, detected during the analysis of glycated haemoglobin (HbA1C) by high performance liquid chromatography
    Y Moriwaki
    Third Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    J Clin Pathol 53:854-7. 2000
  3. ncbi request reprint Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid)
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1 Nishinomiya, Hyogo 663 8501, Japan
    Clin Chim Acta 356:35-57. 2005
  4. ncbi request reprint Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu
    T Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Horm Metab Res 36:231-7. 2004
  5. doi request reprint Relationship between plasma uridine and insulin resistance in patients with non-insulin-dependent diabetes mellitus
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Japan
    Nucleosides Nucleotides Nucleic Acids 29:504-8. 2010
  6. ncbi request reprint A simple method of selecting gout patients for treatment with uricosuric agents, using spot urine and blood samples
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Japan
    J Rheumatol 29:1937-41. 2002
  7. doi request reprint Biochemistry of uridine in plasma
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Clin Chim Acta 412:1712-24. 2011
  8. ncbi request reprint Human xanthine dehydrogenase cDNA sequence and protein in an atypical case of type I xanthinuria in comparison with normal subjects
    T Yamamoto
    Third Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    Clin Chim Acta 304:153-8. 2001
  9. ncbi request reprint Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol
    T Yamamoto
    Third Department of Internal Medicine, Hyogo College of Medicine, Japan
    J Rheumatol 28:2294-7. 2001
  10. ncbi request reprint Effect of beer on the plasma concentrations of uridine and purine bases
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Metabolism 51:1317-23. 2002

Collaborators

Detail Information

Publications58

  1. ncbi request reprint 21-hydroxylase deficiency associated with male infertility: report of 2 cases with gene analyses
    Chihiro Sumida
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Japan
    Intern Med 50:1317-21. 2011
    ..Dexamethasone and then clomiphene were administered in Case 1, and dexamethasone in Case 2. Spermatogenesis was somewhat improved in both patients and pregnancy achieved in Case 2, though spontaneous abortion later occurred...
  2. pmc Abnormal haemoglobins, Hb Takamatsu and Hb G-Szuhu, detected during the analysis of glycated haemoglobin (HbA1C) by high performance liquid chromatography
    Y Moriwaki
    Third Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    J Clin Pathol 53:854-7. 2000
    ..However, HbA1C concentrations measured by latex immunoagglutination and fructosamine concentrations were within the normal range...
  3. ncbi request reprint Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid)
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1 Nishinomiya, Hyogo 663 8501, Japan
    Clin Chim Acta 356:35-57. 2005
    ....
  4. ncbi request reprint Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu
    T Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Horm Metab Res 36:231-7. 2004
    ....
  5. doi request reprint Relationship between plasma uridine and insulin resistance in patients with non-insulin-dependent diabetes mellitus
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Japan
    Nucleosides Nucleotides Nucleic Acids 29:504-8. 2010
    ..Therefore, we investigated whether plasma uridine was correlated with HOMA-R in patients with non-insulin-dependent diabetes mellitus (NIDDM)...
  6. ncbi request reprint A simple method of selecting gout patients for treatment with uricosuric agents, using spot urine and blood samples
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Japan
    J Rheumatol 29:1937-41. 2002
    ..To develop a simple means of selecting gout patients for treatment with uricosuric agents...
  7. doi request reprint Biochemistry of uridine in plasma
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Clin Chim Acta 412:1712-24. 2011
    ..In contrast, factors that decrease the plasma concentration of uridine are associated with accelerated uridine uptake by cells via the nucleoside transport pathway and decreased pyrimidine synthesis...
  8. ncbi request reprint Human xanthine dehydrogenase cDNA sequence and protein in an atypical case of type I xanthinuria in comparison with normal subjects
    T Yamamoto
    Third Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    Clin Chim Acta 304:153-8. 2001
    ....
  9. ncbi request reprint Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol
    T Yamamoto
    Third Department of Internal Medicine, Hyogo College of Medicine, Japan
    J Rheumatol 28:2294-7. 2001
    ..To investigate whether fenofibrate increases the clearance of purine bases (hypoxanthine, xanthine, uric acid) and oxypurinol...
  10. ncbi request reprint Effect of beer on the plasma concentrations of uridine and purine bases
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Metabolism 51:1317-23. 2002
    ....
  11. doi request reprint Relationship between plasma uridine and urinary urea excretion
    Tuneyoshi Ka
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo 663 6801, Japan
    Metabolism 59:441-5. 2010
    ..These results suggest that an increase in de novo pyrimidine synthesis leads to an increased concentration of uridine in plasma via nitrogen catabolism in healthy subjects with normouricemia and normal blood pressure...
  12. ncbi request reprint Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases
    Tuneyoshi Ka
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Rheumatol 30:1036-42. 2003
    ..To investigate the effects of exercise and beer ingestion separately and combined on the plasma concentration of purine bases...
  13. ncbi request reprint Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise
    Mitsuharu Kaya
    First Department of Physiology, Hyogo College of Medicine, Nishinomiya, Hyogo 663 8501, Japan
    Metabolism 55:103-7. 2006
    ..In addition, they suggest that oxypurinol does not significantly inhibit the exercise-induced increase in plasma concentration of urate...
  14. ncbi request reprint Effect of sauna bathing and beer ingestion on plasma concentrations of purine bases
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Metabolism 53:772-6. 2004
    ....
  15. ncbi request reprint Relationship between serum allantoin and urate in healthy subjects and effects of benzbromarone in gout patients
    Masafumi Kurajoh
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Kinki Central Hospital, Japan
    Int J Clin Pharmacol Ther 50:265-71. 2012
    ..In addition, since uric acid has both pro- and antioxidant actions, a decrease in the serum concentration of uric acid may have an effect on the pro-oxidant-antioxidant balance...
  16. ncbi request reprint Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Metabolism 52:1501-4. 2003
    ..Such findings have not been previously reported for patients with xanthinuria type II...
  17. ncbi request reprint Effects of exercise and grape juice ingestion in combination on plasma concentrations of purine bases and uridine
    Masao Ohno
    Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Clin Chim Acta 388:167-72. 2008
    ....
  18. ncbi request reprint Effects of angiotensin II infusion on renal excretion of purine bases and oxypurinol
    Yuji Moriwaki
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Metabolism 51:893-5. 2002
    ..Accordingly, the hypouricemic effect of allopurinol may be exaggerated in hypertensive gout patients with an enhanced renin-angiotensin system, since an increased biological half-life of oxypurinol is expected in these patients...
  19. doi request reprint Effects of allopurinol on beer-induced increases in plasma concentrations of purine bases and uridine
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Nucleosides Nucleotides Nucleic Acids 27:601-3. 2008
    ....
  20. ncbi request reprint Effect of inosine on the plasma concentration of uridine and purine bases
    Tetsuya Yamamoto
    Third Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Metabolism 51:438-42. 2002
    ....
  21. ncbi request reprint Identification of a new point mutation in hypoxanthine phosphoribosyl transferase responsible for hyperuricemia in a female patient
    Taku Inokuchi
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo 663 8501, Japan
    Metabolism 53:1500-2. 2004
    ..Such results have not been previously reported in a female with partial HPRT deficiency...
  22. ncbi request reprint Effect of octreotide acetate on the plasma concentration and urinary excretion of uridine and purine bases
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Endocr J 49:139-44. 2002
    ....
  23. doi request reprint Effects of ethanol on monosodium urate crystal-induced inflammation
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    Cytokine 42:198-204. 2008
    ..These results strongly suggest that ethanol suppresses the secretion of inflammatory cytokines induced by MSU crystals via a pathway including MAPK (p38, JNK, and ERK1/2, especially p38) and NF-kappaB...
  24. ncbi request reprint Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats
    Yuji Moriwaki
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, 663 8501 Hyogo, Japan
    Acta Diabetol 44:215-8. 2007
    ..These results suggest a role of TNF-alpha in the pathogenesis of diabetic nephropathy and show that TNF-alpha inhibition is a potential therapeutic strategy...
  25. ncbi request reprint Oxidized low-density lipoprotein autoantibodies in patients with primary gout: effect of urate-lowering therapy
    Zenta Tsutsumi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo, 663 8501, Japan
    Clin Chim Acta 339:117-22. 2004
    ..The objective of this work was to determine the degree of LDL oxidation in gout and the effect of allopurinol on LDL oxidation...
  26. ncbi request reprint Effects of sucrose on plasma concentrations and urinary excretion of purine bases
    Terumi Kobayashi
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo, 663 8501, Japan
    Metabolism 56:439-43. 2007
    ..In addition, in the control experiment, all parameters did not change significantly. These results indicate that purine degradation enhanced by sucrose plays a major role in the increased plasma concentration of uric acid...
  27. ncbi request reprint Plasma interleukin (IL)-18 (interferon-gamma-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa cho 1 1, Nishinomiya, Hyogo 663 8501, Japan
    Cytokine 33:21-7. 2006
    ..Further, they suggest that MSU crystals accelerate the processing of IL-18 from an inactive to active form via the activation of caspase 1...
  28. ncbi request reprint Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, and Department of Urology, Nishinomiya Municipal Central Hospital, Hyogo, Japan
    Magn Reson Imaging 24:1389-93. 2006
    ..We considered that elucidation of the characteristic features of a schwannoma would provide helpful preoperative information for diagnosis...
  29. doi request reprint Increased frequency of metabolic syndrome and its individual metabolic abnormalities in Japanese patients with primary gout
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    J Clin Rheumatol 16:109-12. 2010
    ..Gout patients are frequently complicated with hypertension, obesity, dyslipidemia, and/or impaired glucose tolerance, which are components of the metabolic syndrome and risks for atherosclerotic diseases...
  30. ncbi request reprint Compound heterozygous mutation of aquaporin 2 gene in woman patient with congenital nephrogenic diabetes insipidus
    Zenta Tsutsumi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya
    Intern Med 48:437-40. 2009
    ....
  31. ncbi request reprint Autoimmune thyroid disease (Graves' disease and hashimoto's thyroiditis) in two patients with Crohn's disease: case reports and literature review
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya
    Intern Med 44:303-6. 2005
    ..Some immunological processes are suggested to be implicated in the pathogenesis of this association, however, the exact mechanism remains unclear...
  32. ncbi request reprint Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy
    Yuji Moriwaki
    Department of Internal Medicine and the Laboratory of Host Defenses Institute for Advanced Medical Sciences, Hyogo College of Medicine, Nishinomiya, Japan
    Metabolism 52:605-8. 2003
    ..41 pg/mL v 1.94 +/- 0.18 pg/mL; IL-6, 1.64 +/- 1.11 pg/mL v 0.51 +/- 0.05 pg/mL, P <.05, respectively). These results suggest that serum levels of IL-18, TNF-alpha, and IL-6 may have some etiopathogenic roles in diabetic nephropathy...
  33. ncbi request reprint [Effect of ethanol on uric acid level]
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine
    Nihon Rinsho 61:143-7. 2003
  34. ncbi request reprint Coexistent B-cell lymphoma and cutaneous T-cell lymphoma
    Taku Inokuchi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya
    Intern Med 45:641-7. 2006
    ..Autopsy findings showed that the right adrenal and soft tissue masses had an identical B-cell origin. Although the exact mechanism remains unclear, the pathogenesis of this rare association is discussed...
  35. ncbi request reprint [Definition and classification of hyperuricemia]
    Tetsuya Yamamoto
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine
    Nihon Rinsho 66:636-40. 2008
    ....
  36. ncbi request reprint [Effect of foods on serum uric acid level]
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine
    Nihon Rinsho 61:134-7. 2003
  37. doi request reprint Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice
    Michiko Imamura
    Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan
    J Hepatol 51:333-41. 2009
    ..Nalp3 inflammasome reportedly controls caspase-1 activation. Here we investigated the roles of MyD88 and TRIF in P. acnes-induced hepatic granuloma formation and LPS-induced caspase-1 activation for IL-18 release...
  38. ncbi request reprint [Influence of sex and age on serum uric acid level]
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine
    Nihon Rinsho 61:131-3. 2003
  39. ncbi request reprint [Development antihyperuricemic candidates]
    Tetsuya Yamamoto
    Department of Internal Medicine, Hyogo College of Medicine
    Nihon Rinsho 61:209-12. 2003
  40. ncbi request reprint Effect of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism in healthy subjects
    Toshihiro Hamada
    Department of Cardiovascular Medicine, Tottori University Hospital, Yonago
    Intern Med 41:793-7. 2002
    ..The acute effects of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism were evaluated...
  41. ncbi request reprint Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats
    Yasutaka Yamamoto
    Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, Yonago, Japan
    Hypertens Res 29:915-21. 2006
    ..In conclusion, uric acid is a potent stimulator of VSMC proliferation, and allopurinol prevented vascular remodeling in SHR at least in part by inhibiting uric acid concentration...
  42. ncbi request reprint Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients
    Toshihiro Hamada
    Department of Cardiovascular Medicine, Graduate School of Medical Science, Tottori University, Yonago, Japan
    Circ J 71:354-6. 2007
    ..The relationship between plasma uridine levels and blood pressure (BP), and indicators of muscular purine degradation and insulin resistance (IR) has been evaluated in hypertensive (HT) patients...
  43. ncbi request reprint [Blood antioxidant capacity in gout]
    Zenta Tsutsumi
    Hyogo College of Medicine
    Nihon Rinsho 61:465-9. 2003
  44. ncbi request reprint Myocilin Gly252Arg mutation and glaucoma of intermediate severity in Caucasian individuals
    Alex W Hewitt
    Clinical Genetics Unit, Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Arch Ophthalmol 125:98-104. 2007
    ..To determine the phenotype of an Australian pedigree with the myocilin (MYOC) Gly252Arg mutation, comparing it with other pedigrees carrying the same mutation...
  45. ncbi request reprint Total plasma homocysteine is not increased in Japanese patients with gout
    Zenta Tsutsumi
    J Rheumatol 29:1805-6. 2002
  46. ncbi request reprint A novel neuroprotectant against retinal ganglion cell damage in a glaucoma model and an optic nerve crush model in the rat
    Kazumi Maeda
    Department of Ophthalmology, Gifu University School of Medicine, Gifu, Japan
    Invest Ophthalmol Vis Sci 45:851-6. 2004
    ....
  47. ncbi request reprint Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts
    Yoshiharu Kinugasa
    Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University, Yonago, Japan
    Circ J 67:781-7. 2003
    ..These findings may lead to the development of new therapeutic strategies for myocardial ischemia - reperfusion injury...
  48. ncbi request reprint Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14
    Tetsuya Yamamoto
    Department of Oral Surgery, Kochi Medical School, Kohasu, Oko cho, Nankoku, Kochi 783 8505, Japan
    Cell Signal 15:861-9. 2003
    ..These results indicate that, through CD59, the LPS signal is transduced into the nucleus via NF-kappaB activation inducing cytokine generation, which may be involved in dermal and mucosal inflammatory diseases...
  49. ncbi request reprint Ultrasound biomicroscopic classification of zonules in exfoliation syndrome
    Kosuke Inazumi
    Department of Ophthalmology, Gifu University School of Medicine, Japan
    Jpn J Ophthalmol 46:502-9. 2002
    ..In the present study we investigated the usefulness of ultrasound biomicroscopy (UBM) for detecting the early changes of XFS in zonules...
  50. ncbi request reprint Blue light differentially alters cellular redox properties
    Jill B Lewis
    School of Dentistry, Department of Oral Biology and Maxillofacial Pathology, Medical College of Georgia, Augusta, Georgia 30912, USA
    J Biomed Mater Res B Appl Biomater 72:223-9. 2005
    ..The identification of oxidative stress as a mediator of the effects of blue light is a critical first step in defining its biological risks and therapeutic opportunities...
  51. ncbi request reprint Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma
    Wallace L M Alward
    Department of Ophthalmology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    Am J Ophthalmol 136:904-10. 2003
    ..To investigate the association of sequence variations in the optineurin (OPTN) gene in patients with open-angle glaucoma...
  52. ncbi request reprint Neuroprotective effects of R(-)-1-(benzo[b]thiophen-5-yl)-2- [2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588) against retinal ganglion cell death induced by elevated intraocular pressure in rat
    Md Zahidul Karim
    Department of Ophthalmology, Gifu University School of Medicine, Gifu, Japan
    Jpn J Ophthalmol 46:621-6. 2002
    ..We investigated whether T-588 can attenuate retinal ganglion cell (RGC) death induced by elevated intraocular pressure (IOP)...
  53. ncbi request reprint Characteristic cytokine generation patterns in cancer cells and infiltrating lymphocytes in oral squamous cell carcinomas and the influence of chemoradiation combined with immunotherapy on these patterns
    Tetsuya Yamamoto
    Department of Oral Surgery, Kochi Medical School, Nankoku City, Japan
    Oncology 64:407-15. 2003
    ..The objectives of the present study were to investigate cytokine generation patterns in tumor cells and TIL and to examine the influence of cancer therapy on this cytokine production and the cytotoxic activity of TIL...
  54. ncbi request reprint Topographic characteristics of the optic nerve head measured with scanning laser tomography in normal Japanese subjects
    Hideya Uchida
    Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan
    Jpn J Ophthalmol 49:469-76. 2005
    ..In this study, we examined the factors influencing optic disc parameters and hemisphere symmetry obtained with the HRT in normal Japanese subjects...
  55. ncbi request reprint Simple new method for making a rat carotid artery post-angioplasty stenosis model
    Wataro Tsuruta
    Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Neurol Med Chir (Tokyo) 47:525-9. 2007
    ..Homogeneous stenoses due to intimal hyperplasia were demonstrated in cross sections of all cases. This simple and gentle method allows an easily reproducible post-angioplasty stenosis model...
  56. ncbi request reprint A new calcium channel antagonist, lomerizine, alleviates secondary retinal ganglion cell death after optic nerve injury in the rat
    Zahidul Karim
    Department of Ophthalmology, Gifu University Graduate School of Medicine, Japan
    Curr Eye Res 31:273-83. 2006
    ..We investigated whether lomerizine, a new diphenylmethylpiperazine calcium channel blocker, exerted a neuroprotective effect on axonal or retinal damage induced by optic nerve injury in the rat...
  57. ncbi request reprint EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase
    Tetsuya Yamamoto
    Department of Oral Surgery, Faculty of Medicine, Kochi University, Kohasu, Nakoku city, Kochi 783, Japan
    Toxicol Appl Pharmacol 224:318-25. 2007
    ..These results suggest that p57 expression may be an useful indicator for the clinical course of cancers, and could be potentially useful as a target for cancer therapies...
  58. ncbi request reprint A mechanism-based in vitro anticancer drug screening approach for phenolic phytochemicals
    Stephen Hsu
    Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GA 30912 1126, USA
    Assay Drug Dev Technol 1:611-8. 2003
    ..Tumor cell death and normal cell survival are detected simultaneously, in a device that co-cultures normal human cells adjacent to human tumor cells...