Chiharu Tabata

Summary

Affiliation: Hyogo College of Medicine
Country: Japan

Publications

  1. doi request reprint Serum HMGB1 as a diagnostic marker for malignant peritoneal mesothelioma
    Chiharu Tabata
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Clin Gastroenterol 47:684-8. 2013
  2. doi request reprint Serum thioredoxin-1 as a diagnostic marker for malignant peritoneal mesothelioma
    Chiharu Tabata
    Department of Internal Medicine, Division of Respiratory Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Clin Gastroenterol 47:e7-11. 2013
  3. pmc The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice
    C Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Clin Exp Immunol 162:560-7. 2010
  4. ncbi request reprint All-trans-retinoic acid inhibits tumour growth of malignant pleural mesothelioma in mice
    C Tabata
    Division of Respiratory Medicine, Dept of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501 Japan
    Eur Respir J 34:1159-67. 2009
  5. doi request reprint A novel clinical role for angiopoietin-1 in malignant pleural mesothelioma
    C Tabata
    Division of Respiratory Medicine, Dept of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501 Japan
    Eur Respir J 36:1099-105. 2010
  6. ncbi request reprint Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice
    Chiharu Tabata
    Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Immunol 179:708-14. 2007
  7. pmc Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma
    Chiharu Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo, 663 8501, Japan
    BMC Cancer 13:205. 2013
  8. ncbi request reprint Clinical significance of serum vascular endothelial growth factor in malignant pleural mesothelioma
    Akihiro Yasumitsu
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Thorac Oncol 5:479-83. 2010
  9. doi request reprint A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells
    Tai Ichiro Otsuki
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Japan
    Cell Physiol Biochem 30:210-20. 2012
  10. doi request reprint All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production
    Shigeo Hisamori
    Department of Gastrointestinal Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Liver Int 28:1217-25. 2008

Collaborators

Detail Information

Publications43

  1. doi request reprint Serum HMGB1 as a diagnostic marker for malignant peritoneal mesothelioma
    Chiharu Tabata
    Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Clin Gastroenterol 47:684-8. 2013
    ..Here, we investigated serum levels of HMGB1 in patients with MPM and compared them with those of a population that had been exposed to asbestos without developing MPM...
  2. doi request reprint Serum thioredoxin-1 as a diagnostic marker for malignant peritoneal mesothelioma
    Chiharu Tabata
    Department of Internal Medicine, Division of Respiratory Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Clin Gastroenterol 47:e7-11. 2013
    ..Here, we investigated the serum levels of TRX in patients with DMPM and compared them with those of a population that had been exposed to asbestos but did not have DMPM...
  3. pmc The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice
    C Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
    Clin Exp Immunol 162:560-7. 2010
    ..These data suggest the clinical use of Calpeptin for the prevention of pulmonary fibrosis...
  4. ncbi request reprint All-trans-retinoic acid inhibits tumour growth of malignant pleural mesothelioma in mice
    C Tabata
    Division of Respiratory Medicine, Dept of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501 Japan
    Eur Respir J 34:1159-67. 2009
    ..These data may provide a rationale to explore the clinical use of ATRA for the treatment of MPM...
  5. doi request reprint A novel clinical role for angiopoietin-1 in malignant pleural mesothelioma
    C Tabata
    Division of Respiratory Medicine, Dept of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501 Japan
    Eur Respir J 36:1099-105. 2010
    ..We propose the possibility that Ang-1 plays an important role in MPM tumour growth and our data suggest that the serum concentration of Ang-1 could be useful as prognostic factor...
  6. ncbi request reprint Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice
    Chiharu Tabata
    Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Immunol 179:708-14. 2007
    ..These data may provide a rationale to explore clinical use of Thal for the prevention of pulmonary fibrosis...
  7. pmc Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma
    Chiharu Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo, 663 8501, Japan
    BMC Cancer 13:205. 2013
    ..Here, we investigated serum levels of HMGB1 in patients with MPM and compared them with those of a population that had been exposed to asbestos without developing MPM...
  8. ncbi request reprint Clinical significance of serum vascular endothelial growth factor in malignant pleural mesothelioma
    Akihiro Yasumitsu
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    J Thorac Oncol 5:479-83. 2010
    ..Here, we investigated the serum levels of VEGF in patients with MPM in comparison with a population that had been exposed to asbestos without developing MPM...
  9. doi request reprint A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells
    Tai Ichiro Otsuki
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Japan
    Cell Physiol Biochem 30:210-20. 2012
    ..A(3) adenosine receptor mediates apoptosis in cancer cells via diverse signaling pathways. The present study examined A(3) adenosine receptor-mediated apoptosis in Lu-65 cells, a human giant cell lung carcinoma cell line...
  10. doi request reprint All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production
    Shigeo Hisamori
    Department of Gastrointestinal Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Liver Int 28:1217-25. 2008
    ..We have recently reported that all-trans-retinoic acid (ATRA) suppresses the transdifferentiation and proliferation of lung fibroblasts and prevents radiation- or bleomycin-induced lung fibrosis...
  11. doi request reprint Clinical significance of serum angiopoietin-1 in malignant peritoneal mesothelioma
    Koji Mikami
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 1
    Cancer Invest 31:511-5. 2013
    ..This is the first report about the relationship between angiopoietin-1 and peritoneal mesothelioma. ..
  12. ncbi request reprint All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis
    Chiharu Tabata
    Horizontal Medical Research Organization, Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan
    Am J Respir Crit Care Med 174:1352-60. 2006
    ..Pulmonary fibrosis is characterized by progressive worsening in pulmonary function leading to high incidence of death. Currently, however, there has been little progress in effective preventive and therapeutic strategies...
  13. doi request reprint Pleural effusion VEGF levels as a prognostic factor of malignant pleural mesothelioma
    Noriko Hirayama
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501, Japan
    Respir Med 105:137-42. 2011
    ..Here, we investigated the pleural effusion VEGF levels in patients with MPM and compared them to those of a population with a non-malignant pleuritis or lung cancer involving malignant pleural effusion...
  14. doi request reprint Heme oxygenase-1 promoter polymorphism is associated with risk of malignant mesothelioma
    Aki Murakami
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo 663 8501, Japan
    Lung 190:333-7. 2012
    ..The HO-1 gene promoter carries (GT)n repeats whose number is inversely related to transcriptional activity of the HO-1 gene...
  15. doi request reprint Sphingosine suppresses mesothelioma cell proliferation by inhibiting PKC-╬┤ and inducing cell cycle arrest at the G(0)/G(1) phase
    Hisaya Okuwa
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Japan
    Cell Physiol Biochem 30:995-1004. 2012
    ..Sphingosine regulates cellular differentiation, cell growth, and apoptosis. The present study aimed at understanding sphingosine-regulated mesothelioma cell proliferation...
  16. ncbi request reprint All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice
    Kae Okoshi
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Surg Res 150:53-9. 2008
    ..We have recently reported that all-trans-retinoic acid (ATRA) prevents radiation- or bleomycin-induced lung fibrosis. Here, we examined the impact of ATRA on the mouse model of radiation-induced intestinal fibrosis...
  17. doi request reprint Is serum thioredoxin-1 a useful clinical marker for malignant pleural mesothelioma?
    Risa Maeda
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    Antioxid Redox Signal 15:685-9. 2011
    ..The difference in overall survival between the groups with lower and higher serum TRX levels was significant. Our data suggest that serum TRX concentration could be a useful clinical marker for MPM...
  18. ncbi request reprint Newly synthesized anticancer drug HUHS1015 is effective on malignant pleural mesothelioma
    Yoshiko Kaku
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Japan
    Cancer Sci 105:883-9. 2014
    ..Taken together, the results of the present study indicate that HUHS1015 could be developed as an effective anticancer drug for treatment of malignant pleural mesothelioma. ..
  19. doi request reprint Clinical significance of pleural effusion mesothelin in malignant pleural mesothelioma
    Shusai Yamada
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Clin Chem Lab Med 49:1721-6. 2011
    ..This study investigated the pleural effusion mesothelin levels in patients with MPM and compared them to those of a population with a non-malignant pleuritis or lung cancer involving malignant pleural effusion...
  20. ncbi request reprint All-trans retinoic acid modulates radiation-induced proliferation of lung fibroblasts via IL-6/IL-6R system
    Chiharu Tabata
    Dept of Respiratory Medicine, Graduate School of Medicine, Kyoto Univ 54 Shogoin Kawaharacho, Sakyo ku, Kyoto, Japan 606 8507
    Am J Physiol Lung Cell Mol Physiol 290:L597-606. 2006
    ..ATRA is expected to have an advantage for radiotherapy in its antitumor effects, as reported previously, and to prevent radiotherapy-induced pulmonary injury...
  21. ncbi request reprint A novel PP2A enhancer induces caspase-independent apoptosis of MKN28 gastric cancer cells with high MEK activity
    Ayako Tsuchiya
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya 663 8501, Japan
    Cancer Lett 347:123-8. 2014
    ..Taken together, these results indicate that diDCP-LA-PI induces caspase-independent apoptosis of Lu65 and MKN28 human cancer cells, for the latter cells by suppressing MEK activity through PP2A-catalyzed dephosphorylation. ..
  22. ncbi request reprint Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt
    Eisuke Shibata
    Department of Thoracic Oncology, Hyogo College of Medicine, Nishinomiya, Japan
    Cell Physiol Biochem 32:871-9. 2013
    ..Accumulating evidence has suggested that free fatty acids (FFAs) interact with protein kinases and protein phosphatases. The present study examined the effect of FFAs on protein phosphatases and Akt...
  23. ncbi request reprint Double-hit lymphoma demonstrating t(6;14;18)(p25;q32;q21), suggesting two independent dual-hit translocations, MYC/BCL-2 and IRF4/BCL-2
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan
    J Clin Exp Hematop 53:141-50. 2013
    ..The present rare case arouses interest in view of the possible "dual" activation of both c-MYC and MUM1/IRF4 through two independent dual-translocations, c-MYC/BCL-2 and IRF4/BCL-2...
  24. doi request reprint CD20-negative low-grade B cell lymphoma showing immunophenotypic and genotypic features resembling plasma cell myeloma
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan
    Pathol Res Pract 209:459-62. 2013
    ....
  25. ncbi request reprint Gene therapy using adenovirus against malignant mesothelioma
    Akinobu Gotoh
    Laboratory of Cell and Gene Therapy Institute for Advanced Medical Sciences, Hyogo College of Medicine, Nishinomiya, Japan
    Anticancer Res 32:3743-7. 2012
    ....
  26. doi request reprint Autoimmune pancreatitis associated with myelodysplastic syndrome
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan
    Int Arch Allergy Immunol 151:168-72. 2010
    ....
  27. doi request reprint AMP converted from intracellularly transported adenosine upregulates p53 expression to induce malignant pleural mesothelioma cell apoptosis
    Yoshitaka Nogi
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, Mukogawa cho, Nishinomiya, Japan
    Cell Physiol Biochem 30:61-74. 2012
    ..The present study investigated adenosine-induced apoptosis in human malignant pleural mesothelioma cells...
  28. doi request reprint C reactive protein as a predictor of neutrophil recovery in autoimmune neutropenia
    Chiharu Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 6 8 17 Minamitsukaguchi, Amagasaki, Hyogo, Japan
    Int Immunopharmacol 11:774-7. 2011
    ..We propose the important part of CRP as a predictor of granulopoiesis in patients with neutropenia...
  29. doi request reprint Nodal marginal zone B cell lymphoma with prominent follicular colonization with deletion of chromosome 13
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan
    Pathol Res Pract 208:679-82. 2012
    ..This type of chromosomal abnormality has not been previously reported and may be related to good prognosis in the present case...
  30. doi request reprint Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells
    Ryoji Eguchi
    Laboratory of Cell Transplantation, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Nishinomiya, Hyogo 663 8501, Japan
    Carcinogenesis 33:969-75. 2012
    ..Present study suggests that SFK inhibitors induce caspase-8-dependent apoptosis caused by reduction of Lyn protein in Fyn-deficient mesothelioma cells...
  31. ncbi request reprint [A case of primary lung cancer with cervical tuberculous lymphadenitis]
    Syusai Yamada
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine
    Nihon Kokyuki Gakkai Zasshi 45:720-5. 2007
    ..To our knowledge, there has been no previous report of both primary lung cancer and cervical tuberculous lymphadenitis being present at the time of the first examination. We report this very rare case...
  32. doi request reprint Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells
    Ryoji Eguchi
    Department of Thoracic Oncology, Hyogo College of Medicine, Nishinomiya, Japan
    J Cell Physiol 226:762-8. 2011
    ..These results indicated that As2O3 induces apoptosis of NCI-H2052 cells mainly through JNK1/2 activation, and that ERK1/2 is involved in As2O3-induced apoptosis when JNK1/2 are inactivated...
  33. doi request reprint Disappearing myelodysplastic syndrome-associated hemolytic anemia in leukemic transformation
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan
    Int Arch Allergy Immunol 152:407-12. 2010
    ..Here we report 2 rare cases of acute myeloid leukemia (AML) complicated with hemolytic anemia limited to the myelodysplastic syndrome (MDS) stage, and disappearing in leukemic transformation...
  34. doi request reprint Crosstalk between PI3 kinase/PDK1/Akt/Rac1 and Ras/Raf/MEK/ERK pathways downstream PDGF receptor
    Emma Tabe Eko Niba
    Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Japan
    Cell Physiol Biochem 31:905-13. 2013
    ..The present study was conducted to obtain evidence for this...
  35. ncbi request reprint Immunohistochemical detection of the lymphatic marker podoplanin in diverse types of human cancer cells using a novel antibody
    Tomoya Kono
    Molecular and Cancer Research Unit, HMRO, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int J Oncol 31:501-8. 2007
    ..These findings suggest a potential role of podoplanin in tumor progression in diverse types of human cancers...
  36. doi request reprint Effect of cyclosporine on lymphocytic variant hypereosinophilic syndrome
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, Japan
    Int Immunopharmacol 16:488-91. 2013
    ..Cytotoxic agents may be necessary to cure this serious disease. Moreover, target therapy for IL-8 may be a new strategy for L-HES with high IL-8 and low IL-5 concentrations...
  37. ncbi request reprint Postoperative complications after induction chemoradiotherapy in patients with non-small-cell lung cancer
    Shiro Fujita
    Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, 54 Syogoin Kawaracho, Kyoto 606 8507, Japan
    Eur J Cardiothorac Surg 29:896-901. 2006
    ..This study evaluates the risks of postoperative complications in 124 patients with non-small-cell lung cancer who received pre-operative induction chemoradiotherapy and surgery...
  38. ncbi request reprint Low dose cepharanthine ameliorates immune thrombocytopenic purpura associated with multiple myeloma
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, 6 8 17 Minamitsukaguchi, Amagasaki, Hyogo, Japan
    Int Immunopharmacol 13:242-4. 2012
    ..We propose the usefulness of cepharanthine in management of this rare disease...
  39. doi request reprint Possible prediction of underlying lymphoma by high sIL-2R/ferritin ratio in hemophagocytic syndrome
    Chiharu Tabata
    Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Ann Hematol 91:63-71. 2012
    ..1%. We propose serum sIL-2R/ferritin ratio as a novel useful marker for predicting underlying malignant lymphoma in HPS patients...
  40. ncbi request reprint Hemophagocytic syndrome in elderly patients with underlying autoimmune diseases
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, 6 8 17 Minamitsukaguchi, Amagasaki, Hyogo 661 0012, Japan
    Clin Rheumatol 28:461-4. 2009
    ..We consider the diagnosis of AAHS should be carefully made when macrophages phagocytosing blood cells are observed in BM smear without hyperferritinemia in elderly patients with autoimmune diseases...
  41. ncbi request reprint Adult T-cell lymphoma mimicking Henoch-Sch├Ânlein purpura
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, 6 8 17 Minamitsukaguchi, Amagasaki, Hyogo 661 0012, Japan
    Mod Rheumatol 17:57-62. 2007
    ..Later he developed lymphoma and was treated with chemotherapy. This rare case suggests the importance of skin biopsies to seek the underlying pathology in adult HSP...
  42. ncbi request reprint Expansion of large granular lymphocytes following Pseudomonas infection in a patient with adult-onset Still's disease
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, 6 8 17 Minamitsukaguchi, Amagasaki, 661 0012, Japan
    Mod Rheumatol 16:101-4. 2006
    ..The increased LGL cells were CD3(+)CD8(+), and disappeared promptly after the administration of antibiotics combined with prednisolone, with subsequent stabilization of her general condition...
  43. doi request reprint Management of myocardial infarction in immune thrombocytopenic purpura with anti-phospholipid antibodies
    Rie Tabata
    Department of Internal Medicine, Hyogo Prefectural Tsukaguchi Hospital, 6 8 17 Minamitsukaguchi, Amagasaki, Hyogo, 661 0012, Japan
    J Thromb Thrombolysis 35:115-8. 2013
    ..Since no occlusion or narrowing was observed in CTCA, she has been safely treated as ITP with immunosuppressive agents throughout the course without antiplatelet or antithrombin therapy...