Kazunari Ishii

Summary

Affiliation: Hyogo Institute for Aging Brain and Cognitive Disorders
Country: Japan

Publications

  1. ncbi request reprint Cerebral blood flow changes in the primary motor and premotor cortices during hyperventilation
    K Ishii
    Division of Neuroimaging Research and Radiology Service, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Ann Nucl Med 12:29-33. 1998
  2. ncbi request reprint Relatively preserved hippocampal glucose metabolism in mild Alzheimer's disease
    K Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders HI ABCD, Himeji, Japan
    Dement Geriatr Cogn Disord 9:317-22. 1998
  3. ncbi request reprint Tc-99m ethyl cysteinate dimer SPECT and 2-[F-18]fluoro-2-deoxy-D-glucose PET in Alzheimer's disease. Comparison of perfusion and metabolic patterns
    K Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Clin Nucl Med 24:572-5. 1999
  4. ncbi request reprint A diagnostic method for suspected Alzheimer's disease using H(2)15O positron emission tomography perfusion Z score
    K Ishii
    Division of Imaging Research, Hyogo Institute for Ageing Brain and Cognitive Disorders, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    Neuroradiology 42:787-94. 2000
  5. ncbi request reprint Comparison of FDG-PET and IMP-SPECT in patients with dementia with Lewy bodies
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Japan
    Ann Nucl Med 18:447-51. 2004
  6. ncbi request reprint Variation in FDG uptakes in different regions in normal human brain as a function of the time (30 and 60 minutes) after injection of FDG
    Kazunari Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Ann Nucl Med 16:299-301. 2002
  7. ncbi request reprint Clinical application of positron emission tomography for diagnosis of dementia
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Ann Nucl Med 16:515-25. 2002
  8. doi request reprint Computer-assisted diagnostic system for neurodegenerative dementia using brain SPECT and 3D-SSP
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    Eur J Nucl Med Mol Imaging 36:831-40. 2009
  9. ncbi request reprint Fully automatic diagnostic system for early- and late-onset mild Alzheimer's disease using FDG PET and 3D-SSP
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo, 670 0981, Japan
    Eur J Nucl Med Mol Imaging 33:575-83. 2006
  10. doi request reprint Voxel-based analysis of gray matter and CSF space in idiopathic normal pressure hydrocephalus
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Dement Geriatr Cogn Disord 25:329-35. 2008

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Cerebral blood flow changes in the primary motor and premotor cortices during hyperventilation
    K Ishii
    Division of Neuroimaging Research and Radiology Service, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Ann Nucl Med 12:29-33. 1998
    ..In the hypocapnic state induced by hyperventilation, the primary motor and premotor CBF shows combined changes with vasoreaction to hypocapnia and increase in activation due to hyperventilation...
  2. ncbi request reprint Relatively preserved hippocampal glucose metabolism in mild Alzheimer's disease
    K Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders HI ABCD, Himeji, Japan
    Dement Geriatr Cogn Disord 9:317-22. 1998
    ....
  3. ncbi request reprint Tc-99m ethyl cysteinate dimer SPECT and 2-[F-18]fluoro-2-deoxy-D-glucose PET in Alzheimer's disease. Comparison of perfusion and metabolic patterns
    K Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Clin Nucl Med 24:572-5. 1999
    ..This study compared Tc-99m ethyl cysteinate dimer (ECD) SPECT images with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG) PET images in the same patients with Alzheimer's disease and determined whether ECD SPECT is as useful as FDG PET clinically...
  4. ncbi request reprint A diagnostic method for suspected Alzheimer's disease using H(2)15O positron emission tomography perfusion Z score
    K Ishii
    Division of Imaging Research, Hyogo Institute for Ageing Brain and Cognitive Disorders, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    Neuroradiology 42:787-94. 2000
    ..946 and 0.584, respectively). These results indicate that a Z map obtained in this way is superior to conventional PET for diagnosing AD...
  5. ncbi request reprint Comparison of FDG-PET and IMP-SPECT in patients with dementia with Lewy bodies
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Japan
    Ann Nucl Med 18:447-51. 2004
    ....
  6. ncbi request reprint Variation in FDG uptakes in different regions in normal human brain as a function of the time (30 and 60 minutes) after injection of FDG
    Kazunari Ishii
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
    Ann Nucl Med 16:299-301. 2002
    ..The authors' goal was to determine whether FDG uptakes in various regions of the brain are different for early and late scanning time in positron emission tomography (PET)...
  7. ncbi request reprint Clinical application of positron emission tomography for diagnosis of dementia
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Ann Nucl Med 16:515-25. 2002
    ..FDG-PET is a very useful tool for the diagnosis of early AD and for the differential diagnosis of dementia. I also describe clinical applications of PET for the diagnosis of dementia in Japan...
  8. doi request reprint Computer-assisted diagnostic system for neurodegenerative dementia using brain SPECT and 3D-SSP
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    Eur J Nucl Med Mol Imaging 36:831-40. 2009
    ..To develop a computer-assisted automated diagnostic system to distinguish among Alzheimer disease (AD), dementia with Lewy bodies (DLB), and other degenerative disorders in patients with mild dementia...
  9. ncbi request reprint Fully automatic diagnostic system for early- and late-onset mild Alzheimer's disease using FDG PET and 3D-SSP
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo, 670 0981, Japan
    Eur J Nucl Med Mol Imaging 33:575-83. 2006
    ..The purpose of this study was to design a fully automatic computer-assisted diagnostic system for early- and late-onset mild Alzheimer's disease (AD)...
  10. doi request reprint Voxel-based analysis of gray matter and CSF space in idiopathic normal pressure hydrocephalus
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Dement Geriatr Cogn Disord 25:329-35. 2008
    ..To investigate regional morphologic changes in idiopathic normal pressure hydrocephalus (INPH) based on diagnosis with INPH Guidelines using voxel-based morphometry...
  11. doi request reprint Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    Eur Radiol 18:2678-83. 2008
    ..Measuring the CA helps in differentiating INPH patients from AD and normally aged subjects...
  12. ncbi request reprint Comparison of the diagnostic performance of FDG-PET and VBM-MRI in very mild Alzheimer's disease
    Takashi Kawachi
    Division of Neuroimaging Research, HIABCD, Himeji, Hyogo, Japan
    Eur J Nucl Med Mol Imaging 33:801-9. 2006
    ....
  13. ncbi request reprint Differences in cerebral metabolic impairment between early and late onset types of Alzheimer's disease
    Setsu Sakamoto
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    J Neurol Sci 200:27-32. 2002
    ..The purpose of this study was to delineate the specific patterns of cerebral glucose metabolism with regard to the time of onset of Alzheimer's disease (AD)...
  14. ncbi request reprint Comparison of regional brain volume and glucose metabolism between patients with mild dementia with lewy bodies and those with mild Alzheimer's disease
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    J Nucl Med 48:704-11. 2007
    ..The aim of this study was to investigate regional differences between morphologic and functional changes in patients with mild dementia with Lewy bodies (DLB) compared with those with Alzheimer's disease (AD)...
  15. ncbi request reprint Voxel-based comparison of regional cerebral glucose metabolism between PSP and corticobasal degeneration
    Kayo Hosaka
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    J Neurol Sci 199:67-71. 2002
    ..The purpose of this study was to elucidate cerebral metabolic differences of these two diseases with cognitive impairments by [18F] fluorodeoxyglucose (FDG) and positron emission tomography (PET)...
  16. ncbi request reprint Comparison of gray matter and metabolic reduction in mild Alzheimer's disease using FDG-PET and voxel-based morphometric MR studies
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo, 670 0981, Japan
    Eur J Nucl Med Mol Imaging 32:959-63. 2005
    ..The aim of this study was to investigate regional differences between morphologic and functional changes in the same patients with mild Alzheimer's disease (AD) using statistical parametric mapping (SPM) and voxel-based morphometry (VBM)...
  17. ncbi request reprint Detectability of hypometabolic regions in mild Alzheimer disease: function of time after the injection of 2-[fluorine 18]-fluoro-2-deoxy-D-glucose
    Setsu Sakamoto
    Department of Radiology, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    AJNR Am J Neuroradiol 26:843-7. 2005
    ..The aim of this study was to evaluate the sensitivity of the early scanning (ES) compared with late scanning (LS) for demonstrating decreased regional glucose metabolism in patients with Alzheimer disease (AD)...
  18. ncbi request reprint Automatic volumetric measurement of segmented brain structures on magnetic resonance imaging
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    Radiat Med 24:422-30. 2006
    ..The purpose of this study was to produce a fully automatic volumetric segmented brain image system (AVSIS) and to evaluate its utility for measuring hippocampal volumes and total intracranial volume (TIV)...
  19. doi request reprint Comparison of grey matter and metabolic reductions in frontotemporal dementia using FDG-PET and voxel-based morphometric MR studies
    Tomonori Kanda
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Hyogo, Japan
    Eur J Nucl Med Mol Imaging 35:2227-34. 2008
    ..The aim of this study was to investigate the regional differences between the morphologic and functional changes in the same patients with frontotemporal dementia (FTD) using statistical parametric mapping and voxel-based morphometry (VBM)...
  20. ncbi request reprint Fully automatic differential diagnosis system for dementia with Lewy bodies and Alzheimer's disease using FDG-PET and 3D-SSP
    Atsushi K Kono
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo, 670 0981, Japan
    Eur J Nucl Med Mol Imaging 34:1490-7. 2007
    ..To evaluate a fully automatic computer-assisted diagnostic system for mild dementia with Lewy bodies (DLB), permitting distinction from mild Alzheimer's disease (AD)...
  21. ncbi request reprint Gender differences in cerebral glucose metabolism: a PET study
    Takashi Kawachi
    Division of Imaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    J Neurol Sci 199:79-83. 2002
    ..Here, we evaluated gender differences of cerebral glucose metabolism under the resting state in a voxel-based analysis...
  22. ncbi request reprint Cerebral perfusion pattern of idiopathic normal pressure hydrocephalus studied by SPECT and statistical brain mapping
    Hiroki Sasaki
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    Ann Nucl Med 21:39-45. 2007
    ..To investigate the specific pattern of cerebral blood flow (CBF) in subjects with idiopathic normal pressure hydrocephalus (iNPH) using voxel-based analysis...
  23. ncbi request reprint Usefulness of intravascular ultrasonography for treatment of a ruptured vertebral dissecting aneurysm
    Atsushi K Kono
    Department of Radiology, Hyogo Brain and Heart Center, 520 Saishoko, Himeji, Hyogo 670 0981, Japan
    Radiat Med 24:577-82. 2006
    ..After stent implantation, Guglielmi detachable coil embolization was performed. Further experience is necessary to refine the technique, but IVUS may be useful to improve the safety of stent-assisted embolization...
  24. doi request reprint Myocardial scintigraphy may predict the conversion to probable dementia with Lewy bodies
    Haruhiko Oda
    From the Institute for Aging Brain and Cognitive Disorders H O, A T, K i S, Y Y, S O and Department of Radiology K I, R K, Hygo Brain and Heart Center, Himeji, Hyogo and the Neurocognitive Disorders Center K I, Kinki University Faculty of Medicine, Osakasayama, Osaka, Japan
    Neurology 81:1741-5. 2013
    ..To compare the usefulness of brain perfusion SPECT and (123)I-metaiodobenzylguanidine ((123)I-MIBG) in predicting the conversion of possible dementia with Lewy bodies (DLB) to probable DLB...
  25. doi request reprint Global cerebral hypoperfusion in a patient with transient global amnesia
    Yumiko Yamane
    Institute for Aging Brain and Cognitive Disorders, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo, Japan
    J Comput Assist Tomogr 32:415-7. 2008
    ..This case suggests that SPECT study is useful in revealing the pathophysiological mechanism of TGA and that TGA attacks are associated with global cerebral blood flow change...
  26. ncbi request reprint Voxel-based morphometric comparison between early- and late-onset mild Alzheimer's disease and assessment of diagnostic performance of z score images
    Kazunari Ishii
    Department of Radiology, Hyogo Brain and Heart Center, Saisho Ko 520, Himeji 670 0981, Hyogo, Japan
    AJNR Am J Neuroradiol 26:333-40. 2005
    ..We sought to delineate the specific patterns of cerebral gray matter loss with regard to onset of Alzheimer's disease (AD) by using MR imaging and VBM and to evaluate the diagnostic performance of VBM with Z score images...
  27. ncbi request reprint Database of normal human cerebral blood flow, cerebral blood volume, cerebral oxygen extraction fraction and cerebral metabolic rate of oxygen measured by positron emission tomography with 15O-labelled carbon dioxide or water, carbon monoxide and oxygen:
    Hiroshi Ito
    Department of Radiology and Nuclear Medicine, Akita Research Institute of Brain and Blood Vessels, Akita, Japan
    Eur J Nucl Med Mol Imaging 31:635-43. 2004
    ..However, the overall inter-individual variation in CBF, CBV, OEF and CMRO(2) was acceptably small. Building a database of normal cerebral haemodynamics obtained by the(15)O-PET methods may be practicable...
  28. doi request reprint Regional cerebral blood flow in healthy volunteers measured by the graph plot method with iodoamphetamine SPECT
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Ann Nucl Med 25:255-60. 2011
    ..The aim of this study was to measure normal regional CBF in older healthy subjects with IMP SPECT and the graph plot method...
  29. ncbi request reprint Prediction of hyperperfusion after carotid endarterectomy by brain SPECT analysis with semiquantitative statistical mapping method
    Kohkichi Hosoda
    Department of Neurosurgery, Hyogo Brain and Heart Center, Himeji, Japan
    Stroke 34:1187-93. 2003
    ..The aim of this study was to investigate the relationship between preoperative cerebral blood flow (CBF) abnormalities and postoperative hyperperfusion through the use of statistical brain mapping analysis...
  30. ncbi request reprint Glucose metabolic dysfunction in subjects with a clinical dementia rating of 0.5
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Hyogo 670 0981, Himeji, Japan
    J Neurol Sci 215:71-4. 2003
    ..To investigate the cerebral glucose metabolism of subjects who had a Clinical Dementia Rating (CDR) of 0.5, we studied 40 subjects whose CDR was 0.5 and 40 age-matched healthy subjects...
  31. ncbi request reprint Necessity of a uniform start for scanning after FDG injection in brain PET study
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji Central Hospital, Japan
    Ann Nucl Med 20:329-31. 2006
    ..The authors' goal was to show the importance of starting scanning at a uniform time after F-18 fluorodeoxyglucose injection in positron emission tomography (PET) brain study...
  32. ncbi request reprint PET is better than perfusion SPECT for early diagnosis of Alzheimer's disease -- for
    Kazunari Ishii
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saisho Ko, Himeji, Hyogo 670 0981, Japan
    Eur J Nucl Med Mol Imaging 32:1463-5. 2005
  33. ncbi request reprint Evaluation of cortical atrophy between progressive supranuclear palsy and corticobasal degeneration by hemispheric surface display of MR images
    Masato Taki
    Hyogo Brain and Heart Center, Department of Radiology and Nuclear Medicine, Saisho Ko 520, Himeji, Hyogo 670 0981, Japan
    AJNR Am J Neuroradiol 25:1709-14. 2004
    ..Our purpose was to determine the features of cortical atrophy in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) by means of a hemispheric surface display generated with MR images...
  34. ncbi request reprint Early disappearance of calcification in posterior paraspinal muscles in a patient with rhabdomyolysis associated with neuroleptic malignant syndrome
    Hiroki Sasaki
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, 520 Saishoko, Himeji, Hyogo 670 0981, Japan
    Radiat Med 24:463-6. 2006
    ..After 2.5 months, CT showed that the calcification had completely disappeared. Bone scintigraphy anticipated calcification, and CT demonstrated a unique course of early disappearance of the calcification...
  35. doi request reprint Late gadolinium enhancement on cardiac magnetic resonance imaging: is it associated with a higher incidence of nonsustained ventricular tachycardia in patients with idiopathic dilated cardiomyopathy?
    Atsushi K Kono
    Department of Radiology and Nuclear Medicine, Hyogo Brain and Heart Center, Himeji, Japan
    Jpn J Radiol 28:355-61. 2010
    ..Some idiopathic dilated cardiomyopathy (DCM) patients have fibrosis in the myocardium and show LGE during cardiac MRI. The purpose of this study was to investigate the clinical significance of LGE in patients with DCM...
  36. ncbi request reprint Validation of anatomical standardization of FDG PET images of normal brain: comparison of SPM and NEUROSTAT
    Kayo Hosaka
    Department of Radiology, Kobe University, Kobe, Japan
    Eur J Nucl Med Mol Imaging 32:92-7. 2005
    ....
  37. ncbi request reprint One-year change in cerebral glucose metabolism in patients with Alzheimer's disease
    Nobutsugu Hirono
    Department of Psychology, Kobegakuin University, 518 Arise, Ikawadani, Nishi ku, Kobe, 651 2180, Japan
    J Neuropsychiatry Clin Neurosci 16:488-92. 2004
    ..Glucose metabolism in these regions may be a useful measure of the progression of AD and a valid surrogate outcome measure of clinical drug trials...
  38. ncbi request reprint Advantage of late scanning in brain 18F-FDG PET
    Kazunari Ishii
    J Nucl Med 47:729; author reply 729. 2006
  39. ncbi request reprint Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis
    Atsushi Yamanaka
    Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    J Immunol 172:3590-6. 2004
    ..These data revealed a novel role for WSX-1 as an inhibitory regulator of cytokine production and inflammation in Con A-induced hepatitis...
  40. ncbi request reprint Polymorphism of the regulatory region of the presenilin-2 gene in sporadic Alzheimer's disease: a case-control study
    Wenxiang Quan
    Department of Psychiatry and Neurology, Kobe Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Kobe, and Hyogo Institute of Aging Brain and Cognitive Disorders, Himeji Brain and Heart Center, Japan
    J Neurol Sci 240:71-5. 2006
    ..The purpose of this study was to determine whether Alzheimer's disease is associated with the presenilin-2 gene polymorphism and the apolipoprotein E genotype in an extended case-control study...
  41. ncbi request reprint Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei
    Yoshiyuki Nishio
    Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan
    J Neurol Sci 260:271-4. 2007
    ..We suggest that the patient's cognitive and behavioral disturbances were associated with disruption of ascending dopaminergic projections to the frontal-subcortical circuits...