Research Topics
Species | Arata TsutsumidaSummaryAffiliation: Hokkaido University Country: Japan Publications
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Detail Information
Publications
Prediction of metastases in melanoma patients with positive sentinel node: histological and molecular approachArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
J Dermatol 34:31-6. 2007..Melanoma patients with small micrometastases (<0.5 mm deep, <1 mm in diameter) and a low level of tyrosinase mRNA had less chances for hematogenous metastases via lymph nodes...
Indications for lymph node dissection in the treatment of extramammary Paget's diseaseArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Hokkaido University, Sapporo, Japan
Dermatol Surg 29:21-4. 2003..In extramammary Paget's disease, compared with patients with carcinoma in situ (CIS), patients with malignancies underlying dermis and subcutaneous tissues or lymph node metastasis appear to have a much worse prognosis...
Suspected case of primary malignant melanoma of the parotid glandArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
Scand J Plast Reconstr Surg Hand Surg 42:105-7. 2008..Despite radiotherapy for brain metastases and combination chemotherapy for lung and lymph node metastases, she died 13 months after the initial operation...
Management of superficial leiomyosarcoma: a retrospective study of 10 casesArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Hokkaido University, Sapporo, Japan
Plast Reconstr Surg 116:8-12. 2005..Superficial leiomyosarcoma is a rare soft-tissue tumor. Management of this tumor, including pathological evaluations and therapies, is not clearly defined in the existing literature...
Treatment strategy for cutaneous malignant melanomaArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Sapporo 060 8638, Japan
Int J Clin Oncol 10:311-7. 2005..Recently there have been advances in the management and treatment of cutaneous melanoma. This article reviews the clinical evidence behind the current treatment recommendations for primary and recurrent cutaneous melanoma in Japan...
PAX4 has the potential to function as a tumor suppressor in human melanomaShinya Hata
Division of Cancer Related Genes, Institute for Genetic Medicine, Hokkaido University, Kita ku, Sapporo 060 0815, Japan
Int J Oncol 33:1065-71. 2008..These results suggest that PAX4 functions as a potent tumor suppressor...
Merkel cell carcinoma of the face: an analysis of 16 cases in the JapaneseAkira Saito
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
J Plast Reconstr Aesthet Surg 62:1272-6. 2009..There is no agreement regarding a staging system and optimal treatment of Merkel cell carcinoma. Some centres have reported results from larger series of patients, but these do not include Asian or Japanese centres...
Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cellsNoriko Saito
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
Pigment Cell Melanoma Res 22:601-10. 2009..These data suggest that laminin-421 secreted by LEC possibly facilitates lymphatic metastasis through the induction of chemotaxis of melanoma cells...
Epigenetic silencing of E- and P-cadherin gene expression in human melanoma cell linesArata Tsutsumida
Division of Cancer-Related Genes, Institute for Genetic Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo 060-0815, Japan
Int J Oncol 25:1415-21. 2004..The results show E-cadherin gene is silenced by at least two distinct mechanisms (methylation and transrepression by Snail) in human melanoma cell lines whereas P-cadherin gene seems to be silenced by methylation but not by snail...
Sentinel node biopsy versus elective lymph node dissection in patients with cutaneous melanoma in a Japanese populationArata Tsutsumida
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
Int J Clin Oncol 12:245-9. 2007..Sentinel node biopsy (SNB) has now replaced ELND, not only in Japan but also worldwide. The objective of this study was to compare the interim outcomes of SNB and ELND...
A new aspect of metastasis in cutaneous cancer: two cases of presacral squamous cell carcinoma with metastases to internal iliac nodesKohei Oashi
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Hokkaido at Sapporo, Sapporo, Japan
Ann Plast Surg 70:79-81. 2013..These cases provide insights into the potential pathway through which a cutaneous tumor disseminates...
Melanoma of thumb: retrospective study for amputation levels, surgical margin and reconstructionHiroshi Furukawa
Department of Plastic and Reconstructive Surgery, University of Hokkaido at Sapporo, Graduate School of Medicine, Kita 15 Nishi 7, Kita ku, Sapporo, 060 8638, Japan
J Plast Reconstr Aesthet Surg 60:24-31. 2007..The reconstructive algorithm for the amputated thumb is proposed and has various tools including free toe to thumb transfer...
A false-negative sentinel lymph node in the parotid gland of a melanoma patient: a new algorithm for SLN biopsy in the parotid glandToshihiko Hayashi
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kitaku, Sapporo, 060 8638, Japan
Int J Clin Oncol 15:504-7. 2010..Therefore, we propose a new algorithm for SLN biopsy in the parotid gland...
Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cellsAkira Saito
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita ku, Sapporo, Japan
Melanoma Res 18:85-94. 2008..We conclude that simvastatin has an antitumor effect on human melanoma cells in vitro via apoptosis and cell cycle arrest. These results suggest that simvastatin may be an effective anticancer drug for malignant melanoma...
Reconstructive considerations after resection of malignant melanoma in the head and neckMitsuru Sekido
Department of Plastic and Reconstructive Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Scand J Plast Reconstr Surg Hand Surg 39:222-6. 2005..Reconstructions with local flaps give better aesthetical and functional results than free flaps and skin grafts. Immediate reconstruction with a flap is safe and it does not affect observation of local recurrences...
Sebaceous carcinoma of the eyelids: a review of 21 casesAkira Saito
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
J Plast Reconstr Aesthet Surg 61:1328-31. 2008..In this article, we studied the management and outcomes of sebaceous carcinoma using the T classification...
Modification of thoracoscopy in pectus excavatum: insertion of both thoracoscope and introducer through a single incision to maximise visualisationHiroshi Furukawa
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Hokkaido at Sapporo, Kita ku, Sapporo, Japan
Scand J Plast Reconstr Surg Hand Surg 41:189-92. 2007..Blood loss was less than 10 ml. There were no intraoperative bleed complications. The modification that we devised may minimise the risk of cardiothoracic and vascular injuries and the procedure is safe...
Alternative approach using the combined technique of nerve crossover and cross-nerve grafting for reanimation of facial palsyYuhei Yamamoto
Department of Plastic and Reconstructive Surgery, Graduate School of Hokkaido University, Sapporo, Japan
Microsurgery 23:251-6. 2003..Facial nerve rehabilitation, based on double innervation by hypoglossal and contralateral healthy facial nerves, takes advantage of reliable and physiological facial reanimation...
Transduction of HOXD3-antisense into human melanoma cells results in decreased invasive and motile activitiesYoshiko Okubo
Division of Cancer Related Genes Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
Clin Exp Metastasis 19:503-11. 2002....
Low incidence of nonsentinel node-positivity after complete lymph node dissection in melanoma patients with positive sentinel nodesArata Tsutsumida
Int J Clin Oncol 12:242-3. 2007
[Analysis of mechanisms for decrease or loss of E-cadherin expression in human melanoma cells]Arata Tsutsumida
Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
Hokkaido Igaku Zasshi 77:439-47. 2002
