K Tanaka

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi request reprint Isolation and characterization of the HC8 subunit gene of the human proteasome
    H Akioka
    Institute for Enzyme Research, Tokushima University, Japan
    Biochem Biophys Res Commun 207:318-23. 1995
  2. pmc Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae
    H Imamura
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita, Japan
    EMBO J 16:2745-55. 1997
  3. ncbi request reprint Formin family proteins in cytoskeletal control
    K Tanaka
    Division of Biochemistry, Hokkaido University School of Medicine, Sapporo, 060 8638, Japan
    Biochem Biophys Res Commun 267:479-81. 2000
  4. ncbi request reprint Biallelic expression of Z-linked genes in male chickens
    A Kuroiwa
    Laboratory of Animal Cytogenetics, Center for Advanced Science and Technology, Hokkaido University, Sapporo, Japan
    Cytogenet Genome Res 99:310-4. 2002
  5. ncbi request reprint Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle
    D Finley
    Trends Biochem Sci 23:244-5. 1998
  6. ncbi request reprint cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9)
    T K Watanabe
    Otsuka GEN Research Institute, Otsuka Pharmaceutical Co Ltd, Tokushima, Japan
    Genomics 50:241-50. 1998
  7. ncbi request reprint Characterization of the mouse PA28 activator complex gene family: complete organizations of the three member genes and a physical map of the approximately 150-kb region containing the alpha- and beta-subunit genes
    K Kohda
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan
    J Immunol 160:4923-35. 1998
  8. pmc Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae
    T Fujiwara
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita 565 0871, Japan
    Mol Biol Cell 9:1221-33. 1998
  9. ncbi request reprint Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit
    K Kohda
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo 060, Japan
    Immunogenetics 47:77-87. 1997
  10. pmc Inorganic polyphosphate and the induction of rpoS expression
    T Shiba
    Division of Molecular Chemistry, Graduate School of Engineering, Hokkaido University, Sapporo 060, Japan
    Proc Natl Acad Sci U S A 94:11210-5. 1997

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Isolation and characterization of the HC8 subunit gene of the human proteasome
    H Akioka
    Institute for Enzyme Research, Tokushima University, Japan
    Biochem Biophys Res Commun 207:318-23. 1995
    ..et al. (1994) J. Mol. Biol. 244, 1117-1124). We mapped the HC8 gene at q23 on human chromosome 14, which differs from the chromosomal locations of nine other proteasomal subunit genes mapped so far...
  2. pmc Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae
    H Imamura
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita, Japan
    EMBO J 16:2745-55. 1997
    ..These results indicate that Bni1p and Bnr1p are potential targets of the Rho family members, interact with profilin and regulate the reorganization of actin cytoskeleton...
  3. ncbi request reprint Formin family proteins in cytoskeletal control
    K Tanaka
    Division of Biochemistry, Hokkaido University School of Medicine, Sapporo, 060 8638, Japan
    Biochem Biophys Res Commun 267:479-81. 2000
    ..Recent evidence indicates that the formin family proteins play a crucial role in the reorganization of the cytoskeleton. In this review, recent advance in the understanding of the functions of formin family proteins is discussed...
  4. ncbi request reprint Biallelic expression of Z-linked genes in male chickens
    A Kuroiwa
    Laboratory of Animal Cytogenetics, Center for Advanced Science and Technology, Hokkaido University, Sapporo, Japan
    Cytogenet Genome Res 99:310-4. 2002
    ..Comparison between expression levels in males and females by real-time quantitative PCR suggested that expression was compensated for the CHD-Z gene but not for the B4GALT1 gene...
  5. ncbi request reprint Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle
    D Finley
    Trends Biochem Sci 23:244-5. 1998
  6. ncbi request reprint cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9)
    T K Watanabe
    Otsuka GEN Research Institute, Otsuka Pharmaceutical Co Ltd, Tokushima, Japan
    Genomics 50:241-50. 1998
    ..Disruption of NAS2 had no effect on cell viability, indicating that the subunit is not essential for proliferation of yeast cells...
  7. ncbi request reprint Characterization of the mouse PA28 activator complex gene family: complete organizations of the three member genes and a physical map of the approximately 150-kb region containing the alpha- and beta-subunit genes
    K Kohda
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan
    J Immunol 160:4923-35. 1998
    ..The Psme1 and Psme2 genes are located approximately 6 kb apart with their 3'-ends pointing toward each other on bands C2 to D1 of mouse chromosome 14, supporting the idea that they emerged by tandem duplication...
  8. pmc Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae
    T Fujiwara
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita 565 0871, Japan
    Mol Biol Cell 9:1221-33. 1998
    ..These results indicate that both Rho1p and Spa2p are involved in the localization of Bni1p at the growth sites where Rho1p regulates reorganization of the actin cytoskeleton through Bni1p...
  9. ncbi request reprint Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit
    K Kohda
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo 060, Japan
    Immunogenetics 47:77-87. 1997
    ..These results were confirmed by fluorescent in situ hybridization analysis that localized Psmb5 to band C2 to proximal D1 of chromosome 14 and Psmb5-ps to band D of chromosome 11...
  10. pmc Inorganic polyphosphate and the induction of rpoS expression
    T Shiba
    Division of Molecular Chemistry, Graduate School of Engineering, Hokkaido University, Sapporo 060, Japan
    Proc Natl Acad Sci U S A 94:11210-5. 1997
    ....
  11. ncbi request reprint The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter
    M Hayashi
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan
    J Immunol 159:2760-70. 1997
    ..Besides the Psmb7 gene previously mapped to chromosome 2, a truncated processed pseudogene, designated Psmb7-ps, was identified and mapped to chromosome X...
  12. ncbi request reprint PA28 subunits of the mouse proteasome: primary structures and chromosomal localization of the genes
    E Kandil
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo 060, Japan
    Immunogenetics 46:337-44. 1997
    ..It appears that the IFN-gamma-inducible alpha- and beta-subunits emerged by gene duplication from a gamma-subunit-like precursor...
  13. ncbi request reprint Mutations in the XPD gene leading to xeroderma pigmentosum symptoms
    T Kobayashi
    Institute for Molecular and Cellular Biology, Osaka University, Japan
    Hum Mutat 9:322-31. 1997
    ..However, the transfectant expressing the XPD cDNA with the missense mutation was slightly more resistant than the parental XP6BE cells. These findings are consistent with the mild symptoms of the XP61OS patient...
  14. pmc Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae
    H Kohno
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita, Japan
    EMBO J 15:6060-8. 1996
    ..Furthermore, this synthetic lethality was caused by the incapability of RhoA to activate Pkc1p, but not glucan synthase. These results suggest that Rho1p regulates cytoskeletal reorganization at least through Bni1p and Pkc1p...
  15. ncbi request reprint Systematic mutational analysis revealing the functional domain organization of Escherichia coli nucleoid protein H-NS
    C Ueguchi
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Japan
    J Mol Biol 263:149-62. 1996
    ..This finding is also addressed with regard to a unique regulatory mechanism (i.e. silencing) for the bgl operon, which is partly mediated by H-NS...
  16. pmc A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae
    H Nonaka
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita, Japan
    EMBO J 14:5931-8. 1995
    ..These results indicate that there are at least two signaling pathways regulated by Rho1p and that one of the downstream targets is Pkc1p, leading to the activation of the MAP kinase cascade...
  17. pmc The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme
    S Taya
    Division of Signal Transduction, Nara Institute of Science and Technology, Ikoma 630 0101, Japan
    J Cell Biol 142:1053-62. 1998
    ..Fam was partially colocalized with AF-6 and interacted with AF-6 in vivo and in vitro. We also showed that AF-6 was ubiquitinated in intact cells, and that Fam prevented the ubiquitination of AF-6...
  18. ncbi request reprint Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae
    T Kamei
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita 565 0871, Osaka, Japan
    J Biol Chem 273:28341-5. 1998
    ..These results indicate that Bnr1p directly interacts with Hof1p as well as with profilin to regulate cytoskeletal functions in S. cerevisiae...
  19. pmc Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta
    S Murata
    Department of Molecular Oncology, Tokyo Metropolitan Institute of Medical Science, and CREST, Japan Science and Technology Corporation, Tokyo 113 8613, Japan
    EMBO J 20:5898-907. 2001
    ..Hence, PA28alpha/beta is not a prerequisite for antigen presentation in general, but plays an essential role for the processing of certain antigens...
  20. ncbi request reprint Sequence polymorphisms, allelic expression status and chromosome locations of the chicken IGF2 and MPR1 genes
    T Yokomine
    Division of Human Genetics, National Institute of Genetics, Graduate University for Advanced Studies, 1-111 Yata, Mishima 411-8540, Japan
    Cytogenet Cell Genet 93:109-13. 2001
    ..IGF2 and MPR1 were mapped on chicken chromosomes 5 and 3, respectively, by fluorescence in situ hybridization, demonstrating conserved linkage homology between mammals and birds...
  21. pmc Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins
    M Fukuchi
    Department of Biochemistry, The Cancer Institute of Japanese Foundation for Cancer Research, and Research for the Future Program, the Japan Society for the Promotion of Science, 1 37 1 Kami Ikebukuro, Toshima ku, Tokyo 170 8455, Japan
    Mol Biol Cell 12:1431-43. 2001
    ..Smad3 bound to ROC1-SCF(Fbw1a) is then exported from the nucleus to the cytoplasm for proteasomal degradation. TGF-beta/Smad3 signaling is thus irreversibly terminated by the ubiquitin-proteasome pathway...
  22. ncbi request reprint Nucleotide sequence analysis of the approximately 35-kb segment containing interferon-gamma-inducible mouse proteasome activator genes
    M Yawata
    CREST, Japan Science and Technology Corporation JST, Hayama 240 0193, Japan
    Immunogenetics 53:119-29. 2001
    ....
  23. ncbi request reprint Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis
    F Ide
    Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
    Carcinogenesis 22:567-72. 2001
    ..Our results clearly demonstrate that the NER gene XPA acts as a defensive factor against 4NQO-induced tongue carcinogenesis in vivo...
  24. ncbi request reprint T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma
    H Takayanagi
    Department of Immunology, Faculty of Medicine and Graduate School of Medicine, University of Tokyo, Japan
    Nature 408:600-5. 2000
    ..Our results may offer a therapeutic approach to treat the inflammation-induced tissue breakdown...
  25. ncbi request reprint The HslU ATPase acts as a molecular chaperone in prevention of aggregation of SulA, an inhibitor of cell division in Escherichia coli
    I S Seong
    School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151 742, South Korea
    FEBS Lett 477:224-9. 2000
    ....
  26. ncbi request reprint cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome
    S L McCutchen-Maloney
    Department of Physiology, The Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    J Biol Chem 275:18557-65. 2000
    ..These results suggest that PI31 plays an important role in control of proteasome function, including that in ubiquitin-dependent pathways of protein degradation...
  27. ncbi request reprint Growth retardation in mice lacking the proteasome activator PA28gamma
    S Murata
    Department of Allergy, Graduate School of Medicine, Japan
    J Biol Chem 274:38211-5. 1999
    ..These results indicate that PA28gamma functions as a regulator of cell proliferation and body growth in mice and suggest that neither PA28alpha nor PA28beta compensates for the PA28gamma deficiency...
  28. pmc Bni1p regulates microtubule-dependent nuclear migration through the actin cytoskeleton in Saccharomyces cerevisiae
    T Fujiwara
    Department of Molecular Biology and Biochemistry, Osaka University Graduate School of Medicine Faculty of Medicine, Suita, Osaka 565 0871, Japan
    Mol Cell Biol 19:8016-27. 1999
    ..Bni1p lacking the Rho-binding region did not suppress the pac1 bni1 growth defect, suggesting a requirement for the Rho1p-Bni1p interaction in microtubule function...
  29. ncbi request reprint The proteasome-dependent proteolytic system
    N Tanahashi
    The Tokyo Metropolitan Institute of Medical Science, and CREST, Japan Science and Technology Corporation
    Mol Biol Rep 26:3-9. 1999
    ....
  30. ncbi request reprint Proteasome activator (PA28) subunits, alpha, beta and gamma (Ki antigen) in NT2 neuronal precursor cells and HeLa S3 cells
    C Wojcik
    Department of Pharmacology, Mount Sinai School of Medicine, New York, NY, USA
    Eur J Cell Biol 77:151-60. 1998
    ..PA28gamma complexed with the proteasome may serve a function other than or in addition to activation and may also have a proteasome-independent function...
  31. ncbi request reprint Shs1p: a novel member of septin that interacts with spa2p, involved in polarized growth in saccharomyces cerevisiae
    A Mino
    Department of Molecular Biology and Biochemistry, Osaka University Medical School, Suita, 565 0871, Japan
    Biochem Biophys Res Commun 251:732-6. 1998
    ..We named this gene SHS1 (Seventh Homolog of Septin). The shs1 mutant cells showed cytokinesis deficiency and Shs1p was localized at the bud neck in budded cells. The Spa2p-Shs1p interactions may play an important role in cytokinesis...
  32. pmc CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p
    K Yokota
    Department of Urology, School of Medicine, Tokushima, Japan
    Mol Biol Cell 7:853-70. 1996
    ....
  33. pmc Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex
    M Kasahara
    Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan
    Proc Natl Acad Sci U S A 93:9096-101. 1996
    ..3 and 9q33-q34). These observations have implications in understanding the genomic organization of the present-day MHC and offer insights into the origin of the MHC...
  34. ncbi request reprint Transcription of the principal sigma-factor genes, rpoD and rpoS, in Pseudomonas aeruginosa is controlled according to the growth phase
    M Fujita
    Department of Biotechnology, Faculty of Engineering, Fukuyama University, Hiroshima, Japan
    Mol Microbiol 13:1071-7. 1994
    ..aeruginosa rpoS was not transcribed in E. coli. By in vitro transcription assaying, P. aeruginosa rpoS was shown to be transcribed by the RNA polymerase fraction containing the principal sigma (sigma 70)-RNA polymerase of P. aeruginosa...
  35. ncbi request reprint Genetic and molecular analysis of the rpoD gene from Lactococcus lactis
    T Araya
    Nutritional Science Laboratory, Morinaga Milk Industry Co, Ltd, Kanagawa, Japan
    Biosci Biotechnol Biochem 57:88-92. 1993
    ..lactis also has the rpoD operon. Surprisingly, introduction of the cloned L. lactis rpoD gene into a rpoD temperature-sensitive mutant of E. coli caused partial complementation...
  36. ncbi request reprint Molecular cloning of cDNA for proteasomes (multicatalytic proteinase complexes) from rat liver: primary structure of the largest component (C2)
    T Fujiwara
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochemistry 28:7332-40. 1989
    ..abstract truncated at 250 words)..
  37. ncbi request reprint Molecular cloning of cDNA for proteasomes from rat liver: primary structure of component C3 with a possible tyrosine phosphorylation site
    K Tanaka
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochemistry 29:3777-85. 1990
    ..abstract truncated at 250 words)..
  38. ncbi request reprint Molecular cloning and sequence analysis of cDNAs for five major subunits of human proteasomes (multi-catalytic proteinase complexes)
    T Tamura
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochim Biophys Acta 1089:95-102. 1991
    ....
  39. ncbi request reprint Systematic characterization of curved DNA segments randomly cloned from Escherichia coli and their functional significance
    K Tanaka
    Laboratory of Microbiology, School of Agriculture, Nagoya University, Japan
    Mol Gen Genet 226:367-76. 1991
    ..It was also demonstrated that an E. coli histone-like protein, named H-NS (or H1a), exhibits a strong affinity for naturally occurring curved DNA sequences in regions upstream promoters...
  40. ncbi request reprint Cloning and analysis of the gene (rpoDA) for the principal sigma factor of Pseudomonas aeruginosa
    K Tanaka
    Institute of Applied Microbiology, University of Tokyo, Japan
    Biochim Biophys Acta 1089:113-9. 1991
    ..RpoDA protein was identified in the extract of the cell carrying a plasmid clone with the rpoDA gene insert by Western blot analysis...
  41. ncbi request reprint Deduced primary structure of a Xenopus proteasome subunit XC3 and expression of its mRNA during early development
    G Fujii
    Laboratory of Molecular Embryology, Faculty of Science, University of Tokyo, Japan
    Biochem Biophys Res Commun 178:1233-9. 1991
    ....
  42. ncbi request reprint Molecular analysis of the Escherichia coli hns gene encoding a DNA-binding protein, which preferentially recognizes curved DNA sequences
    H Yamada
    Laboratory of Microbiology, School of Agriculture, Nagoya University, Japan
    Mol Gen Genet 230:332-6. 1991
    ..It was further demonstrated that, in this hns deletion background, numerous E. coli cellular proteins were either strongly expressed or remarkably repressed, as compared to their expression levels in wild-type cells...
  43. ncbi request reprint PRS3 encoding an essential subunit of yeast proteasomes homologous to mammalian proteasome subunit C5
    D H Lee
    Department of Molecular Biology, College of Natural Sciences, Seoul National University, Korea
    Biochem Biophys Res Commun 182:452-60. 1992
    ..These findings indicate that the PRS3 protein is a subunit of yeast proteasomes that is essential for cell viability...
  44. ncbi request reprint Proteasomes are essential for yeast proliferation. cDNA cloning and gene disruption of two major subunits
    T Fujiwara
    Otsuka Pharmaceutical Co Ltd, Tokushima, Japan
    J Biol Chem 265:16604-13. 1990
    ..These findings demonstrated that YC1 and YC7-alpha are both encoded by a single copy gene and that these genes are essential for proliferation of yeast cells...
  45. ncbi request reprint Changes in expressions of proteasome and ubiquitin genes in human renal cancer cells
    H Kanayama
    Department of Urology, School of Medicine, University of Tokushima, Japan
    Cancer Res 51:6677-85. 1991
    ..These results suggest that the proteasome- and ubiquitin-mediated system is functionally involved in the cancerous state in human kidney...
  46. ncbi request reprint Regulation of gene expression of proteasomes (multi-protease complexes) during growth and differentiation of human hematopoietic cells
    N Shimbara
    Biomaterial Research Institute, Yokohama, Japan
    J Biol Chem 267:18100-9. 1992
    ..We also observed that the nuclear fraction of proteasomes increased in proliferating T-cells and that proteasomes moved rapidly between the nucleus and cytoplasm during differentiation of HL-60 cells...
  47. ncbi request reprint Mutational analysis of the fic promoter recognized by RpoS (sigma 38) in Escherichia coli
    R Utsumi
    Department of Agricultural Chemistry, Kinki University, Nara, Japan
    Biosci Biotechnol Biochem 59:1573-5. 1995
    ..They did not show the stationary phase-specific expression dependent on RpoS in vivo. Furthermore, it was confirmed that they were recognized by E sigma 70 as efficiently as E sigma 38 in vitro...
  48. ncbi request reprint The genes for the alpha-type HC3 (PMSA2) and beta-type HC5 (PMSB1) subunits of human proteasomes map to chromosomes 6q27 and 7p12-p13 by fluorescence in situ hybridization
    K Okumura
    Faculty of Bioresources, Mie University, Japan
    Genomics 27:377-9. 1995
  49. ncbi request reprint cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p
    K Akiyama
    Department of Urology, School of Medicine, Tokushima, Japan
    FEBS Lett 363:151-6. 1995
    ..In either case, both proteins are likely to function equivalently well in either transcription or protein degradation...
  50. ncbi request reprint cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11
    C Tsurumi
    Institute for Enzyme Research, University of Tokushima, Japan
    Eur J Biochem 239:912-21. 1996
    ..These results indicate that p97/Nas1p plays an important regulatory role in the function of the 26S proteasome...
  51. pmc A sigma factor that modifies the circadian expression of a subset of genes in cyanobacteria
    N F Tsinoremas
    Department of Biology, Texas A and M University, College Station, TX 77843, USA
    EMBO J 15:2488-95. 1996
    ..This work demonstrates a direct link between a transcription factor and the manifestation of circadian gene expression...
  52. ncbi request reprint Identification, purification, and characterization of a PA700-dependent activator of the proteasome
    G N DeMartino
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    J Biol Chem 271:3112-8. 1996
    ..Thus, p50 and p42 are subunits common to two protein complexes that regulate the proteasome. The PA700-dependent proteasome activator represents a new member of a growing list of proteins that regulate proteasome activity...
  53. pmc Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli
    K Tanaka
    Institute of Applied Microbiology, University of Tokyo, Japan
    Proc Natl Acad Sci U S A 90:3511-5. 1993
    ..The intracellular level of sigma 38 was demonstrated to increase in vivo upon entry into stationary phase. These results together indicate that sigma 38 is a second principal sigma factor in stationary-phase E. coli...
  54. ncbi request reprint cDNA cloning of rat proteasome subunit RC10-II, assumed to be responsible for trypsin-like catalytic activity
    C Nishimura
    Laboratory of Applied Toxicology, Nippon Kayaku Co Ltd, Gunma, Japan
    FEBS Lett 336:462-6. 1993
    ..R. Dick et al. [Biochemistry 31, 7347-7355, 1992], suggesting that RC10-II is a proteasomal subunit necessary for the expression of tryptic activity...
  55. ncbi request reprint Structure of the 5' upstream region and the regulation of the rpoS gene of Escherichia coli
    Y Takayanagi
    Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan
    Mol Gen Genet 243:525-31. 1994
    ..This strongly suggests that posttranslational regulation is involved in the control of rpoS expression...
  56. pmc res2+, a new member of the cdc10+/SWI4 family, controls the 'start' of mitotic and meiotic cycles in fission yeast
    M Miyamoto
    Okayama Cell Switching Project, ERATO, JRDC, Kyoto, Japan
    EMBO J 13:1873-80. 1994
    ..We conclude that the fission yeast contains two functionally overlapping parallel 'start' systems, Res1-Cdc10 and Res2-Cdc10, the former of which plays a major role in mitotic cycle whereas the latter in meiotic cycle...
  57. ncbi request reprint cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y
    K Akiyama
    Department of Urology, School of Medicine, University of Tokushima, Japan
    Science 265:1231-4. 1994
    ..Thus, interferon gamma may induce subunit replacements of X and Y by LMP7 and LMP2, respectively, producing proteasomes perhaps more appropriate for the immunological processing of endogenous antigens...
  58. ncbi request reprint Isolation and characterization of alpha-type HC3 and beta-type HC5 subunit genes of human proteasomes
    T Tamura
    Institute for Enzyme Research, University of Tokushima, Japan
    J Mol Biol 244:117-24. 1994
    ....
  59. ncbi request reprint Sequence analyses and inter-species comparisons of three novel human proteasomal subunits, HsN3, HsC7-I and HsC10-II, confine potential proteolytic active-site residues
    H G Nothwang
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochim Biophys Acta 1219:361-8. 1994
    ..Based on localization and hydrophobicity, the roles of these amino acid residues as active site and substrate binding site candidates are discussed...
  60. ncbi request reprint Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome
    J Y Ahn
    Institute for Enzyme Research, University of Tokushima, Japan
    FEBS Lett 366:37-42. 1995
    ..They also provide the basis for future structure/function studies of PA28 subunits and the determination of their relative physiological roles in the regulation of proteasome activity...
  61. ncbi request reprint cDNA cloning of p40, a regulatory subunit of the human 26S proteasome, and a homolog of the Mov-34 gene product
    C Tsurumi
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochem Biophys Res Commun 210:600-8. 1995
    ..Thus the p40/Mov-34 protein is a novel essential regulatory subunit of the human 26S proteasome...
  62. ncbi request reprint Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene
    K Tanaka
    Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510
    Hum Mutat 1:271-9. 1992
    ..In addition to tabulating the mutations, the acyl-CoA dehydrogenase gene family, the structure of the MCAD gene and the evolution of 985A-->G mutation are briefly discussed...