Fumihiro Sata

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi request reprint Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss
    Fumihiro Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
    Mol Hum Reprod 11:357-60. 2005
  2. ncbi request reprint Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss
    F Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 9:165-9. 2003
  3. ncbi request reprint A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss
    F Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 9:725-8. 2003
  4. ncbi request reprint Functional maternal catechol-O-methyltransferase polymorphism and fetal growth restriction
    Fumihiro Sata
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Pharmacogenet Genomics 16:775-81. 2006
  5. doi request reprint Exploiting gene-environment interaction to detect adverse health effects of environmental chemicals on the next generation
    Reiko Kishi
    Department of Public Health Sciences, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Basic Clin Pharmacol Toxicol 102:191-203. 2008
  6. ncbi request reprint A polymorphism in the CYP17 gene and intrauterine fetal growth restriction
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 10:49-53. 2004
  7. ncbi request reprint Interleukin-4 gene polymorphism is not involved in the risk of recurrent pregnancy loss
    Yasuaki Saijo
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, Japan
    Am J Reprod Immunol 52:143-6. 2004
  8. ncbi request reprint Influence of genetic polymorphisms of styrene-metabolizing enzymes and smoking habits on levels of urinary metabolites after occupational exposure to styrene
    Mingyue Ma
    Department of Public Health, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Sapporo, Hokkaido 060 8638, Japan
    Toxicol Lett 160:84-91. 2005
  9. doi request reprint Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias
    Susumu Ban
    Department of Public Health, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
    Hum Reprod 23:1466-71. 2008
  10. doi request reprint Adverse birth outcomes associated with maternal smoking and polymorphisms in the N-Nitrosamine-metabolizing enzyme genes NQO1 and CYP2E1
    Seiko Sasaki
    Department of Public Health, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Am J Epidemiol 167:719-26. 2008

Detail Information

Publications35

  1. ncbi request reprint Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss
    Fumihiro Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
    Mol Hum Reprod 11:357-60. 2005
    ..94; 95% CI, 0.57-6.66; 300 mg or more: OR, 5.23; 95% CI, 1.05-25.9; P for trend, 0.03]. It was demonstrated for the first time that an increase in caffeine intake deteriorates the fecundity among susceptible women...
  2. ncbi request reprint Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss
    F Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 9:165-9. 2003
    ..66]. On the other hand, 47.0% of the cases and 49.4% of the controls had the GSTT1 null genotype (OR = 0.95; 95% CI = 0.58-1.55). The results suggest that women with GSTM1 null polymorphism may therefore have an increased risk of RPL...
  3. ncbi request reprint A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss
    F Sata
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 9:725-8. 2003
    ..14; 95% CI, 1.14-4.01; A2/A2 genotype: OR, 2.50; 95% CI, 1.16-5.41; P trend, 0.015]. These results suggest that possession of the A2 variant of CYP17 may predispose to an increased risk of RPL with a gene dosage effect...
  4. ncbi request reprint Functional maternal catechol-O-methyltransferase polymorphism and fetal growth restriction
    Fumihiro Sata
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Pharmacogenet Genomics 16:775-81. 2006
    ..A functional Val158Met polymorphism in the COMT gene has been known as a susceptible marker for breast cancer. The aim of this study was to examine the association between this polymorphism and fetal growth...
  5. doi request reprint Exploiting gene-environment interaction to detect adverse health effects of environmental chemicals on the next generation
    Reiko Kishi
    Department of Public Health Sciences, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Basic Clin Pharmacol Toxicol 102:191-203. 2008
    ..Further studies should elucidate the impact of genetic factors on adverse effects of exposures to dioxin-related chemicals...
  6. ncbi request reprint A polymorphism in the CYP17 gene and intrauterine fetal growth restriction
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Mol Hum Reprod 10:49-53. 2004
    ..5 +/- 2.4 weeks) in 67 women who carried GSTM1 (P < 0.05). The polymorphism of CYP17 that encodes the cytochrome p450c17alpha enzyme might be associated with the pathophysiology underlying fetal growth restriction...
  7. ncbi request reprint Interleukin-4 gene polymorphism is not involved in the risk of recurrent pregnancy loss
    Yasuaki Saijo
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, Japan
    Am J Reprod Immunol 52:143-6. 2004
    ..Several studies have suggested that IL-4 variable number of tandem repeat (VNTR) gene polymorphism is probably associated with different IL-4 production...
  8. ncbi request reprint Influence of genetic polymorphisms of styrene-metabolizing enzymes and smoking habits on levels of urinary metabolites after occupational exposure to styrene
    Mingyue Ma
    Department of Public Health, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Sapporo, Hokkaido 060 8638, Japan
    Toxicol Lett 160:84-91. 2005
    ..The results suggest that genetic susceptibility and lifestyle should be considered in biological monitoring of exposure to styrene...
  9. doi request reprint Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias
    Susumu Ban
    Department of Public Health, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
    Hum Reprod 23:1466-71. 2008
    ..Here, we assessed genetic polymorphisms in estrogen receptor genes and their association with hypospadias...
  10. doi request reprint Adverse birth outcomes associated with maternal smoking and polymorphisms in the N-Nitrosamine-metabolizing enzyme genes NQO1 and CYP2E1
    Seiko Sasaki
    Department of Public Health, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Am J Epidemiol 167:719-26. 2008
    ..These results may help in directing smoking cessation interventions during pregnancy, especially among susceptible women...
  11. doi request reprint Genetic polymorphisms of 17 β-hydroxysteroid dehydrogenase 3 and the risk of hypospadias
    Fumihiro Sata
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Sex Med 7:2729-38. 2010
    ..In this regard, enzymes 17 β-hydroxysteroid dehydrogenase type 3 (17 β HSD3, encoded by HSD17B3) and steroid 5 α-reductase type 2 (encoded by SRD5A2) play crucial roles...
  12. ncbi request reprint Pregnancy-associated plasma protein-A polymorphism and the risk of recurrent pregnancy loss
    Kana Suzuki
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
    J Reprod Immunol 70:99-108. 2006
    ..83; 95% CI, 1.00-8.05; AC+CC genotypes: OR, 1.65; CI, 1.04-2.62). This is the first report on the PAPPA gene polymorphism in women with RPL, demonstrating some association between the investigated polymorphism and the risk of RPL...
  13. ncbi request reprint Circulating cytokines during early pregnancy in women with recurrent spontaneous abortion: decreased TNF-alpha levels in abortion with normal chromosome karyotype
    Hideto Yamada
    Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
    Hokkaido Igaku Zasshi 79:237-41. 2004
    ..The aim of the present study was to assess whether or not serum cytokine concentrations during early pregnancy are related to the subsequent outcomes in women with recurrent spontaneous abortion (RSA)...
  14. ncbi request reprint Parental and neonatal risk factors for cryptorchidism
    Norie Kurahashi
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Med Sci Monit 11:CR274-283. 2005
    ..We investigated the relation between cryptorchidism and lifestyle, occupational exposure and the characteristics of parents and/or the perinatal and delivery characteristics...
  15. ncbi request reprint Genetic factors in fetal growth restriction and miscarriage
    Hideto Yamada
    Associate Professor, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 31:334-45. 2005
    ..It has also been demonstrated that the CYP17 A2 allele has bidirectional effects on human reproduction, including increases in susceptibility to recurrent miscarriage and fetal growth enhancement...
  16. ncbi request reprint Acute effects of styrene inhalation on the neuroendocrinological system of rats and the different effects in male and female rats
    Tomohiro Umemura
    Department of Public Health, School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita ku, 060 8638 Sapporo, Japan
    Arch Toxicol 79:653-9. 2005
    ..These results suggest that styrene exposure may cause hypersecretion of PRL and that the sensitivity to styrene exposure of the female may be higher than that of the male...
  17. doi request reprint Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women
    Sumitaka Kobayashi
    Department of Public Health Sciences, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita ku, Sapporo 060 8638, Hokkaido, Japan
    Toxicol Lett 219:269-78. 2013
    ..Thus, polymorphisms in AHR and CYP1A1 (rs4646903) were associated with maternal dioxin concentrations. However, differences in blood dioxin concentrations were relatively low...
  18. ncbi request reprint [Exposure to endocrine disrupting chemicals and human health: a review of epidemiological studies focused on hypospadias and cryptorchidism]
    Norie Kurahashi
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Nihon Eiseigaku Zasshi 60:15-22. 2005
    ..In the future, a well-designed epidemiological study is needed to elucidate the relation between endocrine disrupting chemicals and genital development...
  19. ncbi request reprint Single nucleotide polymorphisms in the promoter region of the interleukin-6 gene and the risk of recurrent pregnancy loss in Japanese women
    Yasuaki Saijo
    Department of Public Heath, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Fertil Steril 81:374-8. 2004
    ..To investigate the relationships between recurrent pregnancy loss and single nucleotide polymorphisms (-634C-->G and -174G-->C genotypes) in the promoter region of the interleukin (IL)-6 gene in the Japanese population...
  20. doi request reprint The contributions of resistin and adiponectin gene single nucleotide polymorphisms to the genetic risk for polycystic ovary syndrome in a Japanese population
    Tsuyoshi Baba
    Department of Obstetrics and Gynecology, Sapporo Medical University, Sapporo, Hokkaido, Japan
    Gynecol Endocrinol 25:498-503. 2009
    ..The ADIPOQ SNP at -11377 showed no association with PCOS. We conclude that the RETN G/G at -420 genotype is associated with PCOS in Japanese women...
  21. ncbi request reprint [Exposure to endocrine disrupting chemicals and children's health: problems in epidemiological studies]
    Reiko Kishi
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Nihon Eiseigaku Zasshi 61:19-31. 2006
    ..It is suggested that well-designed epidemiological studies such as prospective cohort studies should be performed to elucidate this association...
  22. pmc Effects of prenatal exposure to polychlorinated biphenyls and dioxins on mental and motor development in Japanese children at 6 months of age
    Sonomi Nakajima
    Department of Public Health, Hokkaido University Graduate School of Medicine, and Sapporo Toho Hospital, Japan
    Environ Health Perspect 114:773-8. 2006
    ..In conclusion, the background-level exposure of several isomers of dioxins during the prenatal period probably affects the motor development of 6-month-old infants more than it does their mental development...
  23. ncbi request reprint Stripping operation with sclerotherapy for primary varicose veins due to greater saphenous vein reflux: three-year results
    Keiko Miyazaki
    Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Kita 14, Nishi 5, Kita ku, Sapporo 060 8648, Japan
    World J Surg 27:551-3. 2003
    ..No statistical difference was found between the two groups. The recurrence rate after stripping with sclerotherapy was equivalent to that after stripping with varicectomy. Thus concurrent varicectomy can be replaced with sclerotherapy...
  24. ncbi request reprint Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita ku N15 W7, Sapporo 060 8638, Japan
    Reprod Toxicol 16:735-9. 2002
    ..80-5.62 ng/ml). In Group II, BPA concentrations in AF (0 ng/ml) were lower (P<0.01) than in MS (2.97 ng/ml). MS BPA concentrations in Group II were higher (P<0.01) than in Group I...
  25. ncbi request reprint The estimated prevalence of hypospadias in Hokkaido, Japan
    Norie Kurahashi
    Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Epidemiol 14:73-7. 2004
    ..In this study, we examined whether the prevalence of hypospadias in Hokkaido, Japan, increased or not, using standardized diagnostic criteria. We also investigated the degree of its severity...
  26. pmc Indoor airborne mold spores in newly built dwellings
    Yasuaki Saijo
    Department of Public Health, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, 060 8638, Sapporo, Japan
    Environ Health Prev Med 10:157-61. 2005
    ..To investigate the relationships between sick building syndrome and mold in newly-built dwellings...
  27. ncbi request reprint Effects of pregnancy, age and sex in the metabolism of styrene in rat liver in relation to the regulation of cytochrome P450 enzymes
    Reiko Kishi
    Department of Public Health, Hokkaido University Graduate School of Medicine, Japan
    J Occup Health 47:49-55. 2005
    ..It is very important to elucidate the changes in specific P450 isozyme composition related to their characteristic modification and in their affinity for chemicals...
  28. ncbi request reprint Visual dysfunction in workers exposed to a mixture of organic solvents
    Yingyan Gong
    Department of Public Health, Hokkaido University Graduate School of Medicine, North 15, West 7, Sapporo 060 8638, Japan
    Neurotoxicology 24:703-10. 2003
    ..The results suppose that a low concentration of the mixed organic solvents might affect the retina and optic nerve. However, it needs to be further researched if such an impact affects the Brodmann's areas of visual cortex in the brain...
  29. ncbi request reprint Polycystic ovary syndrome is associated with genetic polymorphism in the insulin signaling gene IRS-1 but not ENPP1 in a Japanese population
    Tsuyoshi Baba
    Department of Obstetrics and Gynecology, Sapporo Medical University, South 1 West 16, Chu o ku, Sapporo, Hokkaido, 060 8543 Japan
    Life Sci 81:850-4. 2007
    ..We conclude that the IRS-1 Gly972Arg polymorphism is associated with PCOS in the Japanese population...
  30. doi request reprint Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood and breast milk collected from 60 mothers in Sapporo City, Japan
    Takashi Todaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Fukuoka 812 8582, Japan
    Chemosphere 72:1152-8. 2008
    ....
  31. pmc Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy
    Koichi Inoue
    Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University, 2 4 41 Ebara, Shinagawa ku, Tokyo 142 8501, Japan
    Environ Health Perspect 112:1204-7. 2004
    ..Further investigation is required to determine the postnatal effects of fetal exposure to FOCs. Key words: cord blood, fluorinated organic compounds, human, PFOA, PFOS, PFOSA, pregnancy...
  32. ncbi request reprint Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan
    Takashi Todaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Chemosphere 69:1228-37. 2007
    ..The results of the present study have indicated that dioxin contamination in the blood of young women in Japan is continuing to decrease...
  33. ncbi request reprint H pylori seropositivity and cytokine gene polymorphisms
    Yasuaki Saijo
    Department of Health Science, Asahikawa Medical College, Midorigaoka, E2 1 1 1, Asahikawa, Hokkaido, Japan
    World J Gastroenterol 13:4445-51. 2007
    ....
  34. ncbi request reprint Effects of the Interaction between Interleukin-6 -634C/G Polymorphism and Smoking on Serum C-Reactive Protein Concentrations
    Yasuaki Saijo
    Department of Health Science, Asahikawa Medical College, Asahikawa, Japan
    Hypertens Res 30:593-9. 2007
    ..Since gene-environment interactions have been insufficiently examined, further studies are required to clarify their effect on inflammation, including CRP elevation...
  35. ncbi request reprint [Symptoms of sick house syndrome and contributory factors; study of general dwellings in Hokkaido]
    Yasuaki Saijo
    Department of Public Health, Graduate School of Medicine, Hokkaido University
    Nihon Koshu Eisei Zasshi 49:1169-83. 2002
    ..The aim of this study was to clarify the "Sick House Syndrome" which has recently received increasing attention, and to investigate relationships between symptoms and the state of general dwellings in Hokkaido...