Research TopicsSpecies | S SakumaSummaryAffiliation: Hokkaido University Country: Japan Publications
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Publications
Receptor protein tyrosine kinase DDR is up-regulated by p53 proteinS Sakuma
Department of Neurosurgery, University of Hokkaido School of Medicine, Kita ku, Sapporo, Japan
FEBS Lett 398:165-9. 1996..Adenovirus-mediated p53 transfection induced a high level of DDR mRNA in SAOS2 human osteosarcoma cells. These results indicate that DDR is up-regulated by the p53 protein...
Clonality and stability of the p53 gene in human astrocytic tumor cells: quantitative analysis of p53 gene mutations by yeast functional assayM Tada
Department of Neurosurgery, University of Hokkaido School of Medicine, Sapporo, Japan
Int J Cancer 67:447-50. 1996..Our results demonstrate the utility of the p53 functional assay for studies of clonality and support the hypothesis of clonal progression of brain tumors in vivo...
RFP is a DNA binding protein associated with the nuclear matrixT Isomura
Department of Pathology, Nagoya University School of Medicine, Japan
Nucleic Acids Res 20:5305-10. 1992..These results thus suggest that RFP may play a role in molecular processes which occur in the nuclear matrix...
Three-dimensional angioarchitecture in transplantable rat fibrosarcomasI Tsunenari
Department of Toxicology and Safety Assessment, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co Ltd, 3-10-1, Yato, Kawanishi Hyogo 666-0193, Japan
J Comp Pathol 126:66-70. 2002..SEM of vascular corrosion casts may prove useful for the evaluation of neovascularization in mesenchymal tumours...
Effects of lipopolysaccharide on a macrophage-like cell line (HS-P) from a rat histiocytic sarcomaJ Yamate
Department of Veterinary Pathology, Graduate School of Agriculture and Biological Science, Osaka Prefecture University, Gakuencho 1 1, Sakai, Osaka, 599 8531, Japan
J Comp Pathol 125:15-24. 2001..The study demonstrated that HS-P cells are highly LPS-responsive, indicating that they would be useful for studies of macrophage functions...
Haptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinaseM Qi
Department of Biochemistry, Nagoya University School of Medicine, Nagoya 466 8550, Japan
J Biol Chem 276:15868-75. 2001....
Malignant fibrous histiocytoma (MFH) cells and macrophages/histiocytes have a common antigen recognized by a monoclonal antibody risen against a rat MFH-derived cloned cell lineD Kumagai
Veterinary Teaching Hospital, College of Agriculture, Osaka Prefecture University, Sakai, Japan
J Vet Med Sci 63:333-5. 2001..These findings suggest the presence of a common antigen recognized by B9 between MFH cells and macrophages/histiocytes. This suggests that MFH cells may express histiocytic nature...
Macrophage-like cell line (HS-P) from a rat histiocytic sarcomaJ Yamate
Department of Veterinary Pathology, College of Agriculture, Osaka Prefecture University, Gakuencho 1 1, Sakai 599 8531, Osaka, Japan
J Comp Pathol 124:183-91. 2001..HS-P cells may prove to be a useful tool for in-vitro studies of macrophage function...
Modulations of glucocorticoid-induced apoptosis linked to the p53 deletion and to the apoptosis susceptibility gene Rapop1 (Radiation-induced apoptosis 1)N Mori
Department of Applied Bioscience, Research Institute for Advanced Science and Technology, Osaka Prefecture University, Sakai, Japan
Oncogene 18:4282-5. 1999..Although it remains to be established whether the genes modulating glucocortocoid-induced apoptosis are identical to p53 and Rapop1, our data suggest that p53 and Rapop1 may participate in glucocorticoid-induced apoptosis of thymocytes...
Characterization of newly established tumor lines from a spontaneous malignant schwannoma in F344 rats: nerve growth factor production, growth inhibition by transforming growth factor-beta1, and macrophage-like phenotype expressionJ Yamate
Laboratories of Veterinary Pathology and Anatomy, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Gakuencho 1 1, Sakai, 599 8531 Osaka, Japan
Acta Neuropathol 106:221-33. 2003..These tumor lines may be useful for studies on pathobiological characteristics of Schwann cells...
