Atsushi Oda

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi CrkL directs ASAP1 to peripheral focal adhesions
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Sapporo 060 8638, Japan
    J Biol Chem 278:6456-60. 2003
  2. ncbi WAVE/Scars in platelets
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Kitaku, Sapporo, 060 8638, Japan
    Blood 105:3141-8. 2005
  3. ncbi DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines
    Hiroshi Nishihara
    Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan
    Blood 100:3968-74. 2002
  4. doi In vitro induction of natural killer T cells from embryonic stem cells prepared using somatic cell nuclear transfer
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, N15W7, Sapporo 060 8638, Japan
    FASEB J 22:2223-31. 2008
  5. ncbi Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2
    Kazuhiko Nagai
    Department of Pharmacology, Hokkaido University Graduate School of Medicine, N15, W7, Sapporo 060 8638, Japan
    Arch Biochem Biophys 452:29-37. 2006
  6. pmc Constitutively active Stat5A and Stat5B promote adipogenesis
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, North 15 West 7, Kita ku, Sapporo, 060 8638, Japan
    Environ Health Prev Med 16:247-52. 2011
  7. ncbi [Mass spectrometry for platelet biochemistry]
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Sapporo, 060 8638, Japan
    Seikagaku 76:651-4. 2004
  8. doi JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells
    Noriko Urushibara
    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041 8611, Japan
    Comp Biochem Physiol C Toxicol Pharmacol 149:468-75. 2009
  9. doi Expansion of functional human mucosal-associated invariant T cells via reprogramming to pluripotency and redifferentiation
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, Sapporo 060 8638, Japan
    Cell Stem Cell 12:546-58. 2013
  10. ncbi A novel mouse model for invariant NKT cell study
    Hiroshi Wakao
    Environmental Biology, School of Medicine, Hokkaido University, Sapporo, Japan
    J Immunol 179:3888-95. 2007

Collaborators

Detail Information

Publications22

  1. ncbi CrkL directs ASAP1 to peripheral focal adhesions
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Sapporo 060 8638, Japan
    J Biol Chem 278:6456-60. 2003
    ..An SH2-mutated CrkL, which cannot localize at focal adhesions, failed to recruit ASAP1 into focal adhesions. Thus, CrkL appears to be a lynchpin between ASAP1 and peripheral focal adhesions...
  2. ncbi WAVE/Scars in platelets
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Kitaku, Sapporo, 060 8638, Japan
    Blood 105:3141-8. 2005
    ..These data suggest that the 3 WAVE isoforms exhibit common and distinct features and may potentially be involved in the regulation of actin cytoskeleton in platelets...
  3. ncbi DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines
    Hiroshi Nishihara
    Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan
    Blood 100:3968-74. 2002
    ..Finally, the stable expression of DOCK2-dCS mutant in Jurkat cells was shown to reduce cell attachment. These data suggest the presence of a novel protein complex of CrkL, DOCK2, and Vav to regulate Rac1 in leukemia cell lines...
  4. doi In vitro induction of natural killer T cells from embryonic stem cells prepared using somatic cell nuclear transfer
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, N15W7, Sapporo 060 8638, Japan
    FASEB J 22:2223-31. 2008
    ..Our results indicate that ntESC-derived iNKT cells are transplantable lymphocytes that will be beneficial for the induction of immune tolerance and the treatment of autoimmune diseases, tumors, and infections...
  5. ncbi Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2
    Kazuhiko Nagai
    Department of Pharmacology, Hokkaido University Graduate School of Medicine, N15, W7, Sapporo 060 8638, Japan
    Arch Biochem Biophys 452:29-37. 2006
    ..These data suggest that the novel protein increases OCTN2 by stabilizing the mRNA in endoplasmic reticulum. The protein may be an up-regulator of OCTN2 and is tentatively designated cartregulin...
  6. pmc Constitutively active Stat5A and Stat5B promote adipogenesis
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, North 15 West 7, Kita ku, Sapporo, 060 8638, Japan
    Environ Health Prev Med 16:247-52. 2011
    ....
  7. ncbi [Mass spectrometry for platelet biochemistry]
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Sapporo, 060 8638, Japan
    Seikagaku 76:651-4. 2004
  8. doi JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells
    Noriko Urushibara
    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041 8611, Japan
    Comp Biochem Physiol C Toxicol Pharmacol 149:468-75. 2009
    ..Thus, TBT employs at least two independent signaling cascades to mediate cell death in RTG-2 cells. To our knowledge, this is the first study revealing the relationship between MAPK activation and TBT cytotoxicity in RTG-2 cells...
  9. doi Expansion of functional human mucosal-associated invariant T cells via reprogramming to pluripotency and redifferentiation
    Hiroshi Wakao
    Department of Environmental Biology, School of Medicine, Hokkaido University, Sapporo 060 8638, Japan
    Cell Stem Cell 12:546-58. 2013
    ..Our findings pave the way for further functional analysis of MAIT cells and determination of their therapeutic potential...
  10. ncbi A novel mouse model for invariant NKT cell study
    Hiroshi Wakao
    Environmental Biology, School of Medicine, Hokkaido University, Sapporo, Japan
    J Immunol 179:3888-95. 2007
    ..These mice will be useful for the study on the development of iNKT cells as well as on their functions in the immune system...
  11. ncbi Thrombopoietin upregulates nucleolin mRNA and protein in thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO
    Takatoshi Ito
    Japanese Red Cross, Hokkaido Red Cross Blood Center, Sapporo, Japan
    Mol Cell Biochem 247:75-82. 2003
    ..Thus, these results indicate that the upregulation of nucleolin mRNA and protein may be important for the TPO-induced effects of hematopoietic cells...
  12. ncbi Calpain is a signal transducer and activator of transcription (STAT) 3 and STAT5 protease
    Atsushi Oda
    Laboratory of Environmental Biology, Department of Preventive Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Blood 99:1850-2. 2002
    ..Thus, our study reveals a novel pathway for posttranslational modification of STAT3 and STAT5...
  13. doi Possible application of flow cytometry for evaluation of the structure and functional status of WASP in peripheral blood mononuclear cells
    Masaru Nakajima
    Division of Oral Functional Science, Department of Dentistry for Children and Disabled Person, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
    Eur J Haematol 82:223-30. 2009
    ..It has been shown that WASP may exist in two forms; an activated or inactivated form. Thus, the structural and functional WASP status or configuration could be evaluated by flow cytometric analysis...
  14. ncbi STI571-resistant KT-1 cells are sensitive to interferon-alpha accompanied by the loss of T-cell protein tyrosine phosphatase and prolonged phosphorylation of Stat1
    Takatsune Shimizu
    Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Exp Hematol 31:601-8. 2003
    ..We studied the effects of interferon-alpha (IFN-alpha) on a novel STI571-resistant CML cell line and its molecular mechanisms in vitro...
  15. ncbi Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation
    Naohide Watanabe
    Blood Center, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Blood 102:541-8. 2003
    ....
  16. ncbi The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery
    Koji Eto
    Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, Japan
    Blood 110:3637-47. 2007
    ..These observations clarify indispensable roles for the WAVE2/Abi1 complex in alpha(IIb)beta(3)-mediated lamellipodia by MKs and platelets through Rac and IRSp53, and additionally in thrombopoiesis independent of Rac and IRSp53...
  17. ncbi A functional role of Stat3 in in vivo megakaryopoiesis
    Keita Kirito
    Division of Hematology, Department of Medicine, Jichi Medical School, Tochigi, Japan
    Blood 99:3220-7. 2002
    ..Collectively, our results strongly suggest that Stat3 plays an important role in the early stage of megakaryopoiesis, presumably through the expansion of megakaryocytic progenitor cells...
  18. doi Nanoparticles built by self-assembly of amphiphilic gamma-PGA can deliver antigens to antigen-presenting cells with high efficiency: a new tumor-vaccine carrier for eliciting effector T cells
    Tomoaki Yoshikawa
    Department of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University, 1 6 Yamadaoka, Suita, Osaka 565 0871, Japan
    Vaccine 26:1303-13. 2008
    ..Our results demonstrate that a gamma-PGA NP system for antigen delivery will advance the clinical utility of vaccines against cancer...
  19. ncbi Development of amphiphilic gamma-PGA-nanoparticle based tumor vaccine: potential of the nanoparticulate cytosolic protein delivery carrier
    Tomoaki Yoshikawa
    Department of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University, 1 6 Yamadaoka, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 366:408-13. 2008
    ..Our findings suggest that the gamma-PGA NP system is suitable for the intracellular delivery of protein-based drugs as well as tumor vaccines...
  20. ncbi Lineage-specific expression of granulocyte colony-stimulating factor and thrombopoietin receptors in terminally differentiated hematopoietic cells
    Tomoaki Kuwaki
    Pharmaceutical Development Laboratories, Kirin Brewery Co, Ltd, Gunma, Japan
    Exp Hematol 34:1651-4. 2006
  21. pmc Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac
    Shiro Suetsugu
    Department of Biochemistry, Institute of Medical Science, University of Tokyo, Minato ku, Tokyo 108 8639, Japan
    J Cell Biol 173:571-85. 2006
    ..Purified WAVE2 and purified WAVE2 complex were activated by IRSp53 in a Rac-dependent manner with PIP(3)-containing liposomes. Therefore, IRSp53 optimizes the activity of the WAVE2 complex in the presence of activated Rac and PIP(3)...
  22. ncbi Bernard-soulier syndrome with a homozygous 13 base pair deletion in the signal peptide-coding region of the platelet glycoprotein Ib(beta) gene
    Reiko Watanabe
    Department of Hematology, Keio University, Tokyo, Japan
    Blood Coagul Fibrinolysis 14:387-94. 2003
    ..The molecular defects of this family would help understand the relevance of GPIb(beta) for complex formation of the glycoprotein Ib/IX/V receptor...