Research Topics
Species | Mitsufumi NishioSummaryAffiliation: Hokkaido University Country: Japan Publications
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Detail Information
Publications
Tumor necrosis factor-alpha inhibits generation of glycophorin A+ cells by CD34+ cellsWeiguo Xiao
Department of Internal Medicine II, Hokkaido University School of Medicine, Sapporo, Japan
Exp Hematol 30:1238-47. 2002..The aim of this study was to determine the extent to which human erythroid progenitor cells are sensitive to TNF-alpha, and to relate this to the expression of TNFRs in the erythroid lineage...
Complete remission of splenic marginal zone lymphoma after an acute flare-up of hepatitis B in a hepatitis B virus carrierKatsuya Fujimoto
Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, 060 8638, Japan
Int J Hematol 90:601-4. 2009..This is the first report that a complete remission was achieved in a patient with SMZL after a hepatitis B flare-up...- FCGR3A-158V/F polymorphism may correlate with the levels of immunoglobulin in patients with non-Hodgkin's lymphoma after rituximab treatment as an adjuvant to autologous stem cell transplantationMitsufumi Nishio
Department of Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Eur J Haematol 82:143-7. 2009..The aim of this study is to clarify the relationships between the FCGR3A-158V/F genotype and the levels of serum immunoglobulin after SCT... - Delayed redistribution of CD27, CD40 and CD80 positive B cells and the impaired in vitro immunoglobulin production in patients with non-Hodgkin lymphoma after rituximab treatment as an adjuvant to autologous stem cell transplantationMitsufumi Nishio
Department of Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Br J Haematol 137:349-54. 2007.... - Hypogammaglobulinemia with a selective delayed recovery in memory B cells and an impaired isotype expression after rituximab administration as an adjuvant to autologous stem cell transplantation for non-Hodgkin lymphomaMitsufumi Nishio
Department of Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Eur J Haematol 77:226-32. 2006..The aim of this study is to clarify the mechanism(s) of this hypogammaglobulinemia... - Reduced intensity conditioning regimen with fludarabine, busulfan, and low-dose TBI (Flu-BU2-TBI): clinical efficacy in high-risk patientsMutsumi Takahata
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Am J Hematol 85:243-8. 2010..The Flu-BU2-TBI regimen for high-risk patients showed therapeutic effects equivalent to those for standard-risk patients and favorable outcomes compared with those of other previous RIC regimens... - Regimen-related mucosal injury of the gut increased the incidence of CMV disease after allogeneic bone marrow transplantationAkio Shigematsu
Stem Cell Transplantation Center, Hokkaido University Hospital, Sapporo, Japan
Biol Blood Marrow Transplant 15:679-85. 2009..In summary, risk of CMV disease was significantly decreased in patients without severe mucosal injury of the gut because of the conditioning regimen before engraftment... - Cord blood transplantation with a reduced-intensity conditioning regimen for patients with relapsed aggressive multiple myeloma after cytoreduction with bortezomibIkumi Kasahara
Department of Medicine II, Hokkaido University Graduate School of Medicine, N15 W7, Kita ku, Sapporo, 060 8638, Japan
Int J Hematol 90:413-5. 2009..These results suggested that the timing of CBT with RIC may be very important, and cytoreduction with not only ASCT but also bortezomib could give a promising chance for a successful CBT... - Sequential chemotherapy and myeloablative allogeneic hematopoietic stem cell transplantation for refractory acute lymphoblastic leukemiaKotaro Arita
Stem Cell Transplantation Center, Hokkaido University Hospital, Sapporo, Japan
Int J Hematol 94:291-5. 2011..The third patient relapsed on day 951, while the fourth died on day 179 without disease. Our results indicate that intensified myeloablative HSCT should be considered for patients with refractory ALL... - Effective high-dose chemotherapy combined with CD34+-selected peripheral blood stem cell transplantation in a patient with cutaneous involvement of nasal NK/T-cell lymphomaKazuki Koizumi
Department of Internal Medicine II, Hokkaido University School of Medicine, Sapporo, Japan
Eur J Haematol 72:140-4. 2004..We suggest that marrow-ablative chemotherapy facilitated by autologous stem cell transplantation should be considered part of the primary therapy for subjects with a poor prognosis for nasal NK/T-cell lymphoma with cutaneous involvement... - A comparison of oral mucositis in allogeneic hematopoietic stem cell transplantation between conventional and reduced-intensity regimensHaruhiko Kashiwazaki
Gerodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7, Kita ku, Sapporo, Hokkaido, 060 8586, Japan
Support Care Cancer 20:933-9. 2012..Although the incidences of oral mucositis were almost the same, the need for opioid analgesics and the risk factors for severe oral mucositis differed between CST and RIST patients... - Incidence and risk of postherpetic neuralgia after varicella zoster virus infection in hematopoietic cell transplantation recipients: Hokkaido Hematology Study GroupMasahiro Onozawa
Stem Cell Transplantation Center, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Biol Blood Marrow Transplant 15:724-9. 2009..0092; OR = 9.56; 95% CI, 1.44-63.3) were associated with increased risk of PHN in allogeneic HCT. This study for the first time clarified the risk of PHN in HCT recipients... - Excellent outcome of allogeneic hematopoietic stem cell transplantation using a conditioning regimen with medium-dose VP-16, cyclophosphamide and total-body irradiation for adult patients with acute lymphoblastic leukemiaAkio Shigematsu
Department of Hematology and Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Biol Blood Marrow Transplant 14:568-75. 2008..Medium-dose VP/CY/TBI for adult ALL patients was associated with lower relapse rate and no increase in toxicity, resulting in better survival... - A retrospective analysis of allogeneic hematopoietic stem cell transplantation for adult T cell leukemia/lymphoma (ATL): clinical impact of graft-versus-leukemia/lymphoma effectSouichi Shiratori
Department of Hematology and Oncology, Hokkaido University Graduate School of Medicine, West 7 chome North 15 jo, North Ward, Sapporo, Japan
Biol Blood Marrow Transplant 14:817-23. 2008..Compared to the results of past studies, these results show that allo-HSCT greatly improved the prognosis of ATL and suggest a contribution of the induction of a GVL effect... - Case report: clearance of hepatitis C virus after changing the HAART regimen in a patient infected with hepatitis C virus and the human immunodeficiency virusTomoyuki Endo
Department of Internal Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
J Med Virol 81:979-82. 2009..The HCV RNA disappearance in this case may be due to the direct effect of HAART against HCV rather than restoration of cellular immunity to HCV... - Epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignanciesMitsutoshi Kurosawa
Department of Hematology, National Hospital Organization Hokkaido Cancer Center, 4 2 3 54 Kikusui, Sapporo, 003 0804, Japan
Int J Hematol 96:748-57. 2012..0 % of patients. IFI-attributable mortality rate was higher in HSCT patients than in those receiving chemotherapy alone, but the difference was not statistically significant... - Immunological reconstitution after autologous hematopoietic stem cell transplantation in patients with systemic sclerosis: relationship between clinical benefits and intensity of immunosuppressionToshiyuki Bohgaki
Department of Medicine II, Hokkaido University Graduate School of Medicine, N15, W7, Kita ku, Sapporo 060 8638, Japan
J Rheumatol 36:1240-8. 2009..To analyze the relationship between clinical benefits and immunological changes in patients with systemic sclerosis (SSc) treated with autologous hematopoietic stem cell transplantation (HSCT)... - Non-Hodgkin lymphoma preceded by recalcitrant eczemaKen Natsuga
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Eur J Haematol 79:369-70. 2007 - Professional oral health care reduces oral mucositis and febrile neutropenia in patients treated with allogeneic bone marrow transplantationHaruhiko Kashiwazaki
Gerodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7, Kita ku, Sapporo 060 8586, Japan
Support Care Cancer 20:367-73. 2012..We evaluated the effects of POHC given by dentists and dental hygienists on the development of oral mucositis and febrile neutropenia (FN) after allogeneic bone marrow transplantation (BMT)... - Therapeutic impact of human bone marrow stromal cells expanded by animal serum-free medium for cerebral infarct in ratsTaku Sugiyama
Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Neurosurgery 68:1733-42; discussion 1742. 2011.... - DOCK2 regulates cell proliferation through Rac and ERK activation in B cell lymphomaLei Wang
Laboratory of Cancer Research, Department of Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kitaku, Sapporo 060 8638, Japan
Biochem Biophys Res Commun 395:111-5. 2010..This is the first report to clarify the prominent role of DOCK2 in hematopoietic malignancy... - Successful treatment of acute myelogenous leukemia with favorable cytogenetics by reduced-intensity stem cell transplantationTakeshi Kondo
Stem Cell Transplantation Center, Hokkaido University Hospital, Sapporo 060 8648, Japan
Int J Hematol 91:310-21. 2010..Moreover, there was no relapse in patients with favorable cytogenetics who were in hematological remission prior to RIST. Thus, RIST for AML patients with favorable cytogenetics in remission is safe and effective... - Persistent panhypogammaglobulinemia with selected loss of memory B cells and impaired isotype expression after rituximab therapy for post-transplant EBV-associated autoimmune hemolytic anemiaMitsufumi Nishio
Eur J Haematol 75:527-9. 2005 - Blastic natural killer cell lymphoma/leukemia (CD56-positive blastic tumor): prognostication and categorization according to anatomic sites of involvementRitsuro Suzuki
Division of Molecular Medicine, Aichi Cancer Center, Nagoya, Japan
Cancer 104:1022-31. 2005..Although further investigations are needed to settle a marker for distinction, the presence of cutaneous involvement is a useful prognostic factor... 
BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathwayTomoyuki Endo
Moores Cancer Center and Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California at San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093 0820, USA
Blood 109:703-10. 2007..These findings suggest that inhibitors of protein kinase IKKbeta, which is required for activation of the canonical NF-kappaB pathway, might have a therapeutic role in this disease...- Hepatosplenic alpha/beta T cell lymphoma presenting with cold agglutinin diseaseKoichiro Minauchi
Ann Hematol 86:155-7. 2007 - Multiple skin metastases of amelanotic melanoma originating from the sinonasal mucosaTeruki Yanagi
Acta Derm Venereol 85:554-5. 2005