Seiji Maruo

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. pmc EBNA3C interacts with Gadd34 and counteracts the unfolded protein response
    Jose L Garrido
    University of Pittsburgh and Children s Hospital of Pittsburgh, One Children s Hospital Drive, 4401 Penn Ave, Pittsburgh, PA 15224, USA
    Virol J 6:231. 2009
  2. pmc Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 108:1919-24. 2011
  3. pmc Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 103:19500-5. 2006
  4. pmc Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 106:4419-24. 2009
  5. pmc Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1
    Ami Watanabe
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, N15W7, Kita ku, Sapporo 060 0815, Japan
    J Virol 84:2893-901. 2010
  6. doi request reprint Quantitative evaluation of the role of Epstein-Barr virus immediate-early protein BZLF1 in B-cell transformation
    Koichi Ricardo Katsumura
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Gen Virol 90:2331-41. 2009
  7. pmc Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a critical role in EBV-induced B-cell growth transformation
    Yi Wu
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, N15W7 Kita ku, Sapporo 060 0815, Japan
    J Virol 81:11236-45. 2007
  8. pmc Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes
    Wangrong Wen
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Virol 81:1037-42. 2007
  9. ncbi request reprint Symmetrical localization of extrachromosomally replicating viral genomes on sister chromatids
    Teru Kanda
    Center for Virus Vector Development, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Cell Sci 120:1529-39. 2007
  10. doi request reprint EBV lytic infection enhances transformation of B-lymphocytes infected with EBV in the presence of T-lymphocytes
    Koichi Ricardo Katsumura
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    J Med Virol 84:504-10. 2012

Collaborators

Detail Information

Publications15

  1. pmc EBNA3C interacts with Gadd34 and counteracts the unfolded protein response
    Jose L Garrido
    University of Pittsburgh and Children s Hospital of Pittsburgh, One Children s Hospital Drive, 4401 Penn Ave, Pittsburgh, PA 15224, USA
    Virol J 6:231. 2009
    ..Collectively the data suggest that EBNA3C interacts with Gadd34, activating the upstream component of the UPR (eIF2alpha phosphorylation) while preventing downstream UPR events (XBP1 activation and ATF6 cleavage)...
  2. pmc Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 108:1919-24. 2011
    ..These data indicate that EBNA3C and EBNA3A joint repression of CDKN2A p16(INK4A) and p14(ARF) is essential for LCL growth...
  3. pmc Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 103:19500-5. 2006
    ..These results indicate that EBNA3C has an essential role in cell cycle progression and the growth maintenance of LCLs...
  4. pmc Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth
    Seiji Maruo
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    Proc Natl Acad Sci U S A 106:4419-24. 2009
    ....
  5. pmc Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1
    Ami Watanabe
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, N15W7, Kita ku, Sapporo 060 0815, Japan
    J Virol 84:2893-901. 2010
    ..These results indicate that EBV is essential for the survival of P3HR-1 cells and that BHRF1 functions as a survival factor. Our finding implies a critical contribution of BHRF1 to the pathogenesis of Wp-restricted BLs...
  6. doi request reprint Quantitative evaluation of the role of Epstein-Barr virus immediate-early protein BZLF1 in B-cell transformation
    Koichi Ricardo Katsumura
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Gen Virol 90:2331-41. 2009
    ....
  7. pmc Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a critical role in EBV-induced B-cell growth transformation
    Yi Wu
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, N15W7 Kita ku, Sapporo 060 0815, Japan
    J Virol 81:11236-45. 2007
    ..We conclude that EBER1 and EBER2, despite their structural similarity, have different functions in latently infected lymphoblastoid cells...
  8. pmc Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes
    Wangrong Wen
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Virol 81:1037-42. 2007
    ....
  9. ncbi request reprint Symmetrical localization of extrachromosomally replicating viral genomes on sister chromatids
    Teru Kanda
    Center for Virus Vector Development, Institute for Genetic Medicine, Hokkaido University, Sapporo 060 0815, Japan
    J Cell Sci 120:1529-39. 2007
    ..Thus, we propose that the partitioning of EBNA1 molecules onto sister chromatids during cellular DNA replication underlies the non-stochastic segregation of extrachromosomally replicating viral genomes...
  10. doi request reprint EBV lytic infection enhances transformation of B-lymphocytes infected with EBV in the presence of T-lymphocytes
    Koichi Ricardo Katsumura
    Department of Tumor Virology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    J Med Virol 84:504-10. 2012
    ..These data suggest that lytic gene products could contribute to virus-induced oncogenesis by a paracrine mechanism...
  11. ncbi request reprint [EBV and apoptosis]
    Seiji Maruo
    Tumor Virology, Institute for Genetic Medicine, Hokkaido University
    Nihon Rinsho 64:576-9. 2006
  12. pmc RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines
    Bo Zhao
    Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 103:1900-5. 2006
    ..5-fold. These RNAs encode proteins important in cell adhesion or signaling, transcription, RNA processing, cell-cycle regulation, and survival. Real-time RT-PCR confirmed EBNA2-dependent expression of eight RNAs...
  13. pmc Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical
    Seiji Maruo
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    J Virol 79:10171-9. 2005
    ..Amino acid residues 240 to 300, 386 to 410, and, particularly, C-terminal residues 827 to 944 are therefore likely to contribute to LCL growth through RBP-Jkappa-independent mechanisms...
  14. pmc Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth
    Seiji Maruo
    Department of Medicine and Microbiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Virol 77:10437-47. 2003
    ..The EBNA3AHT-infected LCLs are also useful for genetic and biochemical analyses of the role of EBNA3A domains in LCL growth...
  15. pmc EBNA3A association with RBP-Jkappa down-regulates c-myc and Epstein-Barr virus-transformed lymphoblast growth
    Andrew Cooper
    Virology Program and Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Virol 77:999-1010. 2003
    ....