Shuhei Hige

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
  2. pmc Sensitive assay for quantification of hepatitis B virus mutants by use of a minor groove binder probe and peptide nucleic acids
    Shuhei Hige
    Department of Internal Medicine, Gastroenterology Section, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    J Clin Microbiol 48:4487-94. 2010
  3. ncbi Immunological and mutagenic actions of ribavirin monotherapy preceding combination therapy with interferon for patients with chronic hepatitis C
    Koji Ogawa
    Department of Gastroenterology, Hakodate Municipal Hospital, Hakodate, Japan
    Antivir Ther 14:513-22. 2009
  4. doi The influence of hepatitis B DNA level and antiviral therapy on recurrence after initial curative treatment in patients with hepatocellular carcinoma
    Makoto Chuma
    Department of Gastroenterology and Hematology, Hokkaido University, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    J Gastroenterol 44:991-9. 2009
  5. doi 8-Hydroxy-2'-deoxy-guanosine is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection
    Makoto Chuma
    Department of Gastroentelology and Hematology, Hokkaido University Hospital, Kitaku, Sapporo, Japan
    J Gastroenterol Hepatol 23:1431-6. 2008
  6. doi Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C
    Tomoe Kobayashi
    Department of Gastroenterology, Hokkaido University Hospital, North 17 Jo, West 5 Cho me, Kita ku, Sapporo 060 8638, Japan
    J Gastroenterol 47:1228-37. 2012
  7. doi Efficacy of therapy for advanced hepatocellular carcinoma: intra-arterial 5-fluorouracil and subcutaneous interferon with image-guided radiation
    Makoto Chuma
    Department of Gastroenterology and Hematology, Hokkaido University, Sapporo, Japan
    J Gastroenterol Hepatol 26:1123-32. 2011
  8. doi Relationship between diffusion-weighted magnetic resonance imaging and histological tumor grading of hepatocellular carcinoma
    Mitsuru Nakanishi
    Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Ann Surg Oncol 19:1302-9. 2012
  9. ncbi [Comprehensive strategy for extermination of hepatocellular carcinoma--prevention, diagnosis and treatment]
    Toshiya Kamiyama
    Department of General Surgery, Hokkaido University Graduate School of Medicine, Sapporo 060 8648, Japan
    Hokkaido Igaku Zasshi 86:127-30. 2011
  10. doi Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B
    Shigeru Yoshida
    Department of Health Sciences, Hokkaido University School of Medicine, North 12 West 5, Sapporo, Japan
    Ann Clin Biochem 45:59-64. 2008

Collaborators

Detail Information

Publications18

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
    ....
  2. pmc Sensitive assay for quantification of hepatitis B virus mutants by use of a minor groove binder probe and peptide nucleic acids
    Shuhei Hige
    Department of Internal Medicine, Gastroenterology Section, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    J Clin Microbiol 48:4487-94. 2010
    ..This assay increases the versatility of a sensitive method for the quantification of a single-nucleotide mutation in a heterogeneous population...
  3. ncbi Immunological and mutagenic actions of ribavirin monotherapy preceding combination therapy with interferon for patients with chronic hepatitis C
    Koji Ogawa
    Department of Gastroenterology, Hakodate Municipal Hospital, Hakodate, Japan
    Antivir Ther 14:513-22. 2009
    ..Immunological and virological effects were analysed in patients undergoing treatment with ribavirin monotherapy prior to the initiation of combination therapy with interferon-alpha...
  4. doi The influence of hepatitis B DNA level and antiviral therapy on recurrence after initial curative treatment in patients with hepatocellular carcinoma
    Makoto Chuma
    Department of Gastroenterology and Hematology, Hokkaido University, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    J Gastroenterol 44:991-9. 2009
    ..Prediction and prevention of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) recurrence is an important clinical issue. We investigated whether HBV DNA level and antiviral therapy are associated with HCC recurrence...
  5. doi 8-Hydroxy-2'-deoxy-guanosine is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection
    Makoto Chuma
    Department of Gastroentelology and Hematology, Hokkaido University Hospital, Kitaku, Sapporo, Japan
    J Gastroenterol Hepatol 23:1431-6. 2008
    ..The aim of this study was to determine whether expression of 8-OHdG is a risk factor for the development of hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV) infection...
  6. doi Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C
    Tomoe Kobayashi
    Department of Gastroenterology, Hokkaido University Hospital, North 17 Jo, West 5 Cho me, Kita ku, Sapporo 060 8638, Japan
    J Gastroenterol 47:1228-37. 2012
    ..However, there are very few reports on the hematological effects of RBV monotherapy. Here, hematological changes were monitored in patients with CHC who received RBV monotherapy, and the mechanism of these changes was investigated...
  7. doi Efficacy of therapy for advanced hepatocellular carcinoma: intra-arterial 5-fluorouracil and subcutaneous interferon with image-guided radiation
    Makoto Chuma
    Department of Gastroenterology and Hematology, Hokkaido University, Sapporo, Japan
    J Gastroenterol Hepatol 26:1123-32. 2011
    ..To evaluate the efficacy of intra-arterial 5-fluorouracil (5-FU) and subcutaneous interferon (IFN) combined with image-guided radiation therapy (IGRT) in advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT)...
  8. doi Relationship between diffusion-weighted magnetic resonance imaging and histological tumor grading of hepatocellular carcinoma
    Mitsuru Nakanishi
    Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Ann Surg Oncol 19:1302-9. 2012
    ..The aim of this study was to determine the usefulness of diffusion-weighted magnetic resonance imaging (DWI) for histological tumor grading and preoperative prediction of early HCC recurrence within 6 months of operation...
  9. ncbi [Comprehensive strategy for extermination of hepatocellular carcinoma--prevention, diagnosis and treatment]
    Toshiya Kamiyama
    Department of General Surgery, Hokkaido University Graduate School of Medicine, Sapporo 060 8648, Japan
    Hokkaido Igaku Zasshi 86:127-30. 2011
    ..We hope that this symposium would help the attendance to understand the prevention and treatment for HCC...
  10. doi Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B
    Shigeru Yoshida
    Department of Health Sciences, Hokkaido University School of Medicine, North 12 West 5, Sapporo, Japan
    Ann Clin Biochem 45:59-64. 2008
    ..Several methods allowing detection of mutant strains (YIDD, YVDD) have been reported, but they have no quantitative characteristics. In this study, we explored a unique approach for quantification of each mutant strain...
  11. ncbi Spontaneous rupture of hepatocellular carcinoma supplied by the right renal capsular artery treated by transcatheter arterial embolization
    Yoshihisa Kodama
    Department of Radiology, Hokkaido University, School of Medicine, N15 W7, Kita ku, Sapporo, 060 8638, Japan
    Cardiovasc Intervent Radiol 25:137-40. 2002
    ..With successful TAE, no hepatic failure was related to the treatment. We believe that if tumors are fed only by extrahepatic collateral vessels, TAE may be an effective treatment even in patients with poor liver function...
  12. ncbi Eradication of Helicobacter pylori for primary gastric cancer and secondary gastric cancer after endoscopic mucosal resection
    Motosugu Kato
    Division of Endoscopy, Hokkaido University Hospital, North 14, West 5, Kita ku, Sapporo, 060 8638, Japan
    J Gastroenterol 42:16-20. 2007
    ..A total of 542 subjects have been enrolled in the study. This study will have the statistical power to demonstrate whether H. pylori eradication decreases the incidence and recurrence of gastric cancer...
  13. ncbi Reactivation of hepatitis in a bladder cancer patient receiving chemotherapy
    Hiroshi Higashiyama
    Department of Renal and Genito urinary Surgery, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Sapporo, Japan
    Int Urol Nephrol 39:461-3. 2007
    ..Care should be taken about the risk of reactivation when performing chemotherapy in HBV carriers and prophylaxis by lamivudine should be considered...
  14. ncbi Hyperammonemic encephalopathy in a patient with ureterosigmoidostomy and acute hepatitis: a specific case of fulminant hepatic failure
    Shunsuke Ohnishi
    Department of Gastroenterology and Hematology, Hokkaido University School of Medicine, Sapporo, Japan
    Dig Dis Sci 48:821-3. 2003
  15. ncbi Progressive disappearance of anti-hepatitis B surface antigen antibody and reverse seroconversion after allogeneic hematopoietic stem cell transplantation in patients with previous hepatitis B virus infection
    Masahiro Onozawa
    Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Transplantation 79:616-9. 2005
    ..0% and 39.8% at 2 years and 100.0% and 70.0% at 5 years, respectively. In conclusion, RS is a late-onset complication with high frequency that can be predicted by careful monitoring of progressive decrease in anti-HBs titer...
  16. ncbi Overexpression of the oncoprotein prothymosin alpha triggers a p53 response that involves p53 acetylation
    Takahiko Kobayashi
    Hokkaido University Medical Hospital, Primary Care Medicine, Sapporo, Japan
    Cancer Res 66:3137-44. 2006
    ..Our findings indicate that overexpressed PTMA elicits a p53 response that involves p53 acetylation...
  17. ncbi Intercepting radiotherapy using a real-time tumor-tracking radiotherapy system for highly selected patients with hepatocellular carcinoma unresectable with other modalities
    Hiroshi Taguchi
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 69:376-80. 2007
    ....
  18. ncbi [Measurement of strand-specific hepatic HCV-RNA quantities of patients with hepatitis C virus infection]
    Shuhei Hige
    Department of Internal Medicine, Gastroenterology and Hematology Section, Hokkaido University Graduate School of Medicine
    Nihon Rinsho 62:417-21. 2004