Rie Hasebe

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. pmc Reaction of complement factors varies with prion strains in vitro and in vivo
    Rie Hasebe
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT 59840, USA
    Virology 423:205-13. 2012
  2. doi request reprint Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways
    Rie Hasebe
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, West 9 North 18, Kita ku, Sapporo 060 0818, Japan
    Virology 393:198-209. 2009
  3. pmc Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein
    Rie Hasebe
    Department of Molecular Pathobiology, Hokkaido University Research Center for Zoonosis Control, Kita 20, Nishi 10, Kita ku, Sapporo 001 0020, Japan
    BMC Microbiol 10:165. 2010
  4. pmc Equine major histocompatibility complex class I molecules act as entry receptors that bind to equine herpesvirus-1 glycoprotein D
    Michihito Sasaki
    Department of Molecular Pathobiology, Hokkaido University Research Center for Zoonosis Control, Sapporo 001 0020, Japan
    Genes Cells 16:343-57. 2011
  5. pmc Single amino acid residue in the A2 domain of major histocompatibility complex class I is involved in the efficiency of equine herpesvirus-1 entry
    Michihito Sasaki
    Department of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001 0020, Japan
    J Biol Chem 286:39370-8. 2011
  6. pmc Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation
    Keiko Sakai
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita ku, Sapporo, Japan
    J Virol 87:13433-45. 2013
  7. doi request reprint Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions
    Natsuo Ohsawa
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita ku, Sapporo, Japan
    Microbiol Immunol 57:288-97. 2013
  8. doi request reprint Establishment of tracking system for West Nile virus entry and evidence of microtubule involvement in particle transport
    Yoshinori Makino
    Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, n20, W10, Kita ku, Sapporo 001 0020, Japan
    J Virol Methods 195:250-7. 2014
  9. doi request reprint Characterization of intracellular localization of PrP(Sc) in prion-infected cells using a mAb that recognizes the region consisting of aa 119-127 of mouse PrP
    Takeshi Yamasaki
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Gen Virol 93:668-80. 2012
  10. pmc The region approximately between amino acids 81 and 137 of proteinase K-resistant PrPSc is critical for the infectivity of the Chandler prion strain
    Ryo Shindoh
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Virol 83:3852-60. 2009

Collaborators

Detail Information

Publications16

  1. pmc Reaction of complement factors varies with prion strains in vitro and in vivo
    Rie Hasebe
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT 59840, USA
    Virology 423:205-13. 2012
    ..These results indicate that the reactivity of complement factors differs between prion strains both in vitro and in vivo...
  2. doi request reprint Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways
    Rie Hasebe
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, West 9 North 18, Kita ku, Sapporo 060 0818, Japan
    Virology 393:198-209. 2009
    ..Derm cells via energy- and pH-dependent endocytosis. These results suggest that EHV-1 utilizes multiple endocytic pathways in different cell types to establish productive infection...
  3. pmc Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein
    Rie Hasebe
    Department of Molecular Pathobiology, Hokkaido University Research Center for Zoonosis Control, Kita 20, Nishi 10, Kita ku, Sapporo 001 0020, Japan
    BMC Microbiol 10:165. 2010
    ..Here, we analyzed the capacity of virus-like particles (VLPs) of the highly virulent NY99 6-LP strain (6-LP VLPs) and the low virulence Eg101 strain (Eg VLPs) to cross cultured human endothelial cells...
  4. pmc Equine major histocompatibility complex class I molecules act as entry receptors that bind to equine herpesvirus-1 glycoprotein D
    Michihito Sasaki
    Department of Molecular Pathobiology, Hokkaido University Research Center for Zoonosis Control, Sapporo 001 0020, Japan
    Genes Cells 16:343-57. 2011
    ..Derm cells drastically reduced their susceptibility to EHV-1 infection. These results suggest that equine MHC class I is a functional gD receptor that plays a pivotal role in EHV-1 entry into equine cells...
  5. pmc Single amino acid residue in the A2 domain of major histocompatibility complex class I is involved in the efficiency of equine herpesvirus-1 entry
    Michihito Sasaki
    Department of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001 0020, Japan
    J Biol Chem 286:39370-8. 2011
    ..4 to mediate EHV-1 entry into cells. These results suggest that the amino acid residue at position 173 of the MHC class I molecule is involved in the efficiency of EHV-1 entry...
  6. pmc Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation
    Keiko Sakai
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita ku, Sapporo, Japan
    J Virol 87:13433-45. 2013
    ..These results imply that CD14 plays a role in the disease progression by suppressing anti-inflammatory responses in the brain in the early stage of infection. ..
  7. doi request reprint Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions
    Natsuo Ohsawa
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita ku, Sapporo, Japan
    Microbiol Immunol 57:288-97. 2013
    ..These results suggest that administration of an anti-PrP mAb through a peripheral route is a candidate for the treatment of prion diseases...
  8. doi request reprint Establishment of tracking system for West Nile virus entry and evidence of microtubule involvement in particle transport
    Yoshinori Makino
    Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, n20, W10, Kita ku, Sapporo 001 0020, Japan
    J Virol Methods 195:250-7. 2014
    ..Moreover, fast viral particle movements at the late phase correlated with SVP-microtubule association. ..
  9. doi request reprint Characterization of intracellular localization of PrP(Sc) in prion-infected cells using a mAb that recognizes the region consisting of aa 119-127 of mouse PrP
    Takeshi Yamasaki
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Gen Virol 93:668-80. 2012
    ....
  10. pmc The region approximately between amino acids 81 and 137 of proteinase K-resistant PrPSc is critical for the infectivity of the Chandler prion strain
    Ryo Shindoh
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Virol 83:3852-60. 2009
    ..This finding suggests that the conformation of the region between aa 81 and 137 of the Chandler strain PrP(Sc) molecule is directly associated with prion infectivity...
  11. ncbi request reprint Propagation of swine hemagglutinating encephalomyelitis virus and pseudorabies virus in dorsal root ganglia cells
    Yoko Hara
    Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    J Vet Med Sci 71:595-601. 2009
    ....
  12. doi request reprint Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells
    Takeshi Yamasaki
    Laboratory of Veterinary Hygiene, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    Virology 450:324-35. 2014
    ..These results suggest that the trafficking of exogenously introduced PrP(Sc) from the endo-lysosomal pathway to the endocytic-recycling pathway is important for the establishment of prion infection. ..
  13. doi request reprint Effect of intraventricular infusion of anti-prion protein monoclonal antibodies on disease progression in prion-infected mice
    Chang Hyun Song
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Gen Virol 89:1533-44. 2008
    ..Although the effects on survival varied for different prion strains, the anti-PrP mAb could partly prevent disease progression, even after clinical onset, suggesting immunotherapy as a candidate for treatment of prion diseases...
  14. pmc Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions
    Chang Hyun Song
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    J Virol 83:5918-27. 2009
    ....
  15. ncbi request reprint Passage of equine herpesvirus-1 in suckling mouse brain enhances extraneural virus growth and subsequent hematogenous neuroinvasion
    Rie Hasebe
    Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    J Vet Med Sci 64:907-12. 2002
    ..i. These results suggest that NHH1 neuroinvasion is hematogenous and is correlated with enhanced extraneural virus growth...
  16. doi request reprint Cell density-dependent increase in the level of protease-resistant prion protein in prion-infected Neuro2a mouse neuroblastoma cells
    Satoshi Nakamitsu
    Laboratory of Prion Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo 060 0818, Japan
    J Gen Virol 91:563-9. 2010
    ..The cholesterol content, which is known to influence PrP-res formation, also changed depending on cell density. Our data suggest that alterations in cellular microenvironments controlled by cell density influence PrP-res formation...