J Hamada

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi request reprint CD44 expression and growth factors
    J Hamada
    Division of Cell Biology, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan
    Front Biosci 3:d657-64. 1998
  2. pmc Induction of Tissue Factor Expression in Endothelial Cells by Basic Fibroblast Growth Factor and its Modulation by Fenofibric acid
    Takeaki Kaneko
    Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Thromb J 1:6. 2003
  3. ncbi request reprint Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation
    J Hamada
    Division of Cancer Related Genes, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    J Natl Cancer Inst 93:214-9. 2001
  4. pmc Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells
    H Nagayasu
    Division of Pathology, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan
    Br J Cancer 77:1371-7. 1998
  5. pmc Development of a yeast stop codon assay readily and generally applicable to human genes
    A Kataoka
    First Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan
    Am J Pathol 159:1239-45. 2001
  6. ncbi request reprint Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect
    H Fujita
    Division of Cancer Gene Regulation, Research Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    Int J Cancer 93:773-80. 2001
  7. pmc Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis
    P Dong
    Department of Gynecology, Hokkaido University School of Medicine, Hokkaido University, Sapporo, Japan
    Oncogene 32:3286-95. 2013
  8. ncbi request reprint Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain Protein AIE-75
    S Ishikawa
    Institute for Genetic Medicine Hokkaido University, Division of Cancer Related Genes, 060 0815, Sapporo, Japan
    Gene 267:101-10. 2001

Collaborators

Detail Information

Publications8

  1. ncbi request reprint CD44 expression and growth factors
    J Hamada
    Division of Cell Biology, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan
    Front Biosci 3:d657-64. 1998
    ..The modification of CD44 on both tumor and host cells by growth factors may play an important role in tumor progression...
  2. pmc Induction of Tissue Factor Expression in Endothelial Cells by Basic Fibroblast Growth Factor and its Modulation by Fenofibric acid
    Takeaki Kaneko
    Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Thromb J 1:6. 2003
    ..Fibrate can inhibit TF expression and therefore reduce the thrombogenecity of human atherosclerotic lesions...
  3. ncbi request reprint Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation
    J Hamada
    Division of Cancer Related Genes, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    J Natl Cancer Inst 93:214-9. 2001
    ..In this study, we investigated the irreversible changes induced in ER-1 cells by a 1-month exposure to EGF and the possible involvement of oxidative stress...
  4. pmc Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells
    H Nagayasu
    Division of Pathology, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan
    Br J Cancer 77:1371-7. 1998
    ..These findings suggest that MT suppressed tumour metastasis by intensifying the cell-to-cell contact of endothelial cells, thus preventing tumour cells from invading vascular endothelium...
  5. pmc Development of a yeast stop codon assay readily and generally applicable to human genes
    A Kataoka
    First Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan
    Am J Pathol 159:1239-45. 2001
    ....
  6. ncbi request reprint Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect
    H Fujita
    Division of Cancer Gene Regulation, Research Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
    Int J Cancer 93:773-80. 2001
    ..Gelsolin may function as a metastasis suppressor as well as a tumor suppressor gene. The carboxyl-terminus of gelsolin is important for retardation of cell spreading, reduced chemotasis and metastasis suppression...
  7. pmc Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis
    P Dong
    Department of Gynecology, Hokkaido University School of Medicine, Hokkaido University, Sapporo, Japan
    Oncogene 32:3286-95. 2013
    ..These data provide a novel understanding of the roles of p53 gain-of-function mutations in accelerating tumor progression and metastasis through modulation of the miR-130b-ZEB1 axis. ..
  8. ncbi request reprint Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain Protein AIE-75
    S Ishikawa
    Institute for Genetic Medicine Hokkaido University, Division of Cancer Related Genes, 060 0815, Sapporo, Japan
    Gene 267:101-10. 2001
    ..Because of negative expression of MCC2 in a panel of cancer cell-lines compared to the corresponding normal tissues, we suggest that further study is necessary to investigate a possible role of MCC2 as a tumor suppressor...