Research Topics
Genomes and Genes | Toshihide ArigaSummaryAffiliation: Hokkaido University Country: Japan Publications
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Detail Information
Publications
Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in miceAnton Lennikov
Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
Int J Mol Sci 14:2175-89. 2013..GGA-treatment induced HSP70 expression and ameliorated UV-induced corneal damage through the reduced NF-κB activation and possibly increased Akt phosphorilation...
Replication of a microsatellite genome-wide association study of Behcet's disease in a Korean populationYukihiro Horie
Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Kita 15, Nishi 7, Kita ku, Sapporo 060 8638, Japan
Rheumatology (Oxford) 51:983-6. 2012..To confirm our recent results, these microsatellite markers were examined in a Korean population as a replication study...
Elevation of surfactant protein D, a pulmonary disease biomarker, in the sera of uveitis patients with sarcoidosisNobuyoshi Kitaichi
Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Jpn J Ophthalmol 54:81-4. 2010..In the present study, serum levels of SP-D were measured in patients with uveitis to ascertain whether SP-D is a clinically useful laboratory parameter to diagnose sarcoidosis...
Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian peopleN Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
Br J Ophthalmol 93:1428-30. 2009..There is little information on the demographic and clinical characteristics of Behçet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres...
Macrophage migration inhibitory factor ameliorates UV-induced photokeratitis in miceNobuyoshi Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Exp Eye Res 86:929-35. 2008..In conclusion, UV-damaged cornea is recoverable without MIF, however it takes longer time than normal condition. Cornea is less damaged and can make a quick recovery when ocular tissue is enough supplied with MIF...
Ocular features of Behcet's disease: an international collaborative studyNobuyoshi Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
Br J Ophthalmol 91:1579-82. 2007..To investigate the clinical features of ocular lesions in Behçet's disease in different countries...
The positive role of lumbar puncture in the diagnosis of Vogt-Koyanagi-Harada disease: lymphocyte subsets in the aqueous humor and cerebrospinal fluidNobuyoshi Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, N 15, W 7, Kita ku, Sapporo 060 8638, Japan
Int Ophthalmol 27:97-103. 2007....
Increase in macrophage migration inhibitory factor levels in lacrimal fluid of patients with severe atopic dermatitisNobuyoshi Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, 060 8638, Sapporo, Japan
Graefes Arch Clin Exp Ophthalmol 244:825-8. 2006..Although serum MIF levels may be elevated in severe atopic dermatitis, the quantity of MIF in regional ocular fluid remains unknown. We measured MIF levels in tears (lacrimal fluid) of patients with atopic dermatitis...
Usefulness of quantifying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosisNobuyoshi Kitaichi
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Graefes Arch Clin Exp Ophthalmol 244:433-7. 2006..The purpose of the present study was to investigate the clinical usefulness of quantifying serum KL-6 levels for following-up the patients with sarcoidosis...
Genome variability of human adenovirus type 8 causing epidemic keratoconjunctivitis during 1986-2003 in JapanXue Hai Jin
Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Mol Vis 17:3121-7. 2011..Human adenovirus type 8 (HAdV-8) is one of the major serotypes isolated from patients with EKC. DNA restriction enzyme analyses were performed to investigate the genetic characteristics of the isolates and their chronological pattern...
Five new genome types of adenovirus type 37 caused epidemic keratoconjunctivitis in Sapporo, Japan, for more than 10 yearsToshihide Ariga
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita ku, Sapporo, Hokkaido 060 8638, Japan
J Clin Microbiol 43:726-32. 2005..We conclude that mutations in the adenovirus genome occurred chronologically and that certain mutations were correlated with the epidemics of adenoviral keratoconjunctivitis...
[Clinical and virological studies of nosocomial conjunctivitis infection caused by adenovirus type 37 variant]Hisatoshi Kaneko
Department of Ophthalmology, Fukushima Medical University, School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan
Nippon Ganka Gakkai Zasshi 109:489-96. 2005..Therefore, patients need to be observed carefully. The virological analysis of specimens from conjunctival swabs detected pathogens and provided useful information concerning adenoviral conjunctivitis...
The change of clinical manifestations of patients with Behçet's disease in JapanSatoshi Kotake
Department of Ophthalmology and Visual Science, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Adv Exp Med Biol 528:83-4. 2003
New genome type of adenovirus serotype 4 caused nosocomial infections associated with epidemic conjunctivitis in JapanToshihide Ariga
Department of Ophthalmology and Visual Diseases, Hokkaido University Graduate School of Medicine, Sapporo, Japan
J Clin Microbiol 42:3644-8. 2004..We conclude that the nosocomial infection that appeared in 2001 was caused by a new genome type of AdV-4, which was designated AdV-4c...
Molecular diagnosis of human adenoviruses d and e by a phylogeny-based classification method using a partial hexon sequenceYasushi Shimada
Research and Development Department, Mitsubishi Kagaku Bio-Clinical Laboratories, Inc, Shimura 3-30-1, Itabashi-ku, Tokyo 174-8555, Japan
J Clin Microbiol 42:1577-84. 2004..Each isolate formed a monophyletic cluster along with its respective prototype strain, allowing serotype identification. Partial-hexon-based classification appears to be an effective tool for studying the molecular epidemiology of HAdVs...
