Yuji Yasunaga

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. pmc Patient selection criteria for periacetabular osteotomy or rotational acetabular osteotomy
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Hiroshima University, Hiroshima, Japan
    Clin Orthop Relat Res 470:3342-54. 2012
  2. doi Clinical and radiographical results of 179 thrust plate hip prostheses: 5-14 years follow-up study
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Hiroshima University, Graduate School of Biomedical Sciences, Minami Ku, Hiroshima, Japan
    Arch Orthop Trauma Surg 132:547-54. 2012
  3. ncbi Rotational acetabular osteotomy for advanced osteoarthritis secondary to dysplasia of the hip
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1 2 3, Minami Ku, Hiroshima City 734 8551, Japan
    J Bone Joint Surg Am 88:1915-9. 2006
  4. ncbi Rotational acetabular osteotomy for hip dysplasia: 61 hips followed for 8-15 years
    Yuji Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Acta Orthop Scand 75:10-5. 2004
  5. ncbi Rotational acetabular osteotomy in patients forty-six years of age or older: comparison with younger patients
    Y Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University School of Medicine, Kasumi, Minami Ku, Japan
    J Bone Joint Surg Am 85:266-72. 2003
  6. pmc Shed blood-derived cells from total hip arthroplasty have osteoinductive potential: a pilot study
    Tomokazu Yoshida
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Clin Orthop Relat Res 468:2725-33. 2010
  7. ncbi Prefabrication of vascularized bone graft using a combination of fibroblast growth factor-2 and vascular bundle implantation into a novel interconnected porous calcium hydroxyapatite ceramic
    Tomoyuki Nakasa
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biomed Mater Res A 75:350-5. 2005
  8. ncbi Bone-preserving prosthesis with a single axis for treating osteonecrosis of the femoral head: midterm results for the thrust plate hip prosthesis
    Yuji Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Sci 8:818-22. 2003
  9. doi Efficacy of bone marrow mononuclear cells to promote bone regeneration compared with isolated CD34+ cells from the same volume of aspirate
    Shinji Yasuhara
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi Minami ku, Hiroshima, Japan
    Artif Organs 34:594-9. 2010
  10. ncbi Congenital pseudoarthrosis of the ulna treated with a free vascularized fibular graft
    Osami Suzuki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Plast Reconstr Surg 115:1379-84. 2005

Collaborators

Detail Information

Publications74

  1. pmc Patient selection criteria for periacetabular osteotomy or rotational acetabular osteotomy
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Hiroshima University, Hiroshima, Japan
    Clin Orthop Relat Res 470:3342-54. 2012
    ..Periacetabular osteotomy (PAO) or rotational acetabular osteotomy (RAO) has been used as a joint-preserving procedure. However, the patient selection criteria are not clearly defined...
  2. doi Clinical and radiographical results of 179 thrust plate hip prostheses: 5-14 years follow-up study
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Hiroshima University, Graduate School of Biomedical Sciences, Minami Ku, Hiroshima, Japan
    Arch Orthop Trauma Surg 132:547-54. 2012
    ..We retrospectively evaluated the results of 162 patients (179 hips) who underwent hip arthroplasty using TPP...
  3. ncbi Rotational acetabular osteotomy for advanced osteoarthritis secondary to dysplasia of the hip
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1 2 3, Minami Ku, Hiroshima City 734 8551, Japan
    J Bone Joint Surg Am 88:1915-9. 2006
    ..The purpose of this study was to examine the results of rotational acetabular osteotomy in patients with advanced osteoarthritis secondary to developmental dysplasia of the hip...
  4. ncbi Rotational acetabular osteotomy for hip dysplasia: 61 hips followed for 8-15 years
    Yuji Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Acta Orthop Scand 75:10-5. 2004
    ..Kaplan-Meier survivorship analysis predicted an 89% (95% confidence interval 80-99) prevention of worsening of arthrosis at 10 years. Postoperative joint congruency was a risk factor for progression of arthrosis...
  5. ncbi Rotational acetabular osteotomy in patients forty-six years of age or older: comparison with younger patients
    Y Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University School of Medicine, Kasumi, Minami Ku, Japan
    J Bone Joint Surg Am 85:266-72. 2003
    ..The purpose of the present study was to examine the usefulness of rotational acetabular osteotomy in patients older than forty-six years of age...
  6. pmc Shed blood-derived cells from total hip arthroplasty have osteoinductive potential: a pilot study
    Tomokazu Yoshida
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Clin Orthop Relat Res 468:2725-33. 2010
    ..Cell therapy using autologous cells has been used in the treatment of various medical conditions. The mononuclear cell (MNC) fraction of bone marrow (BM) contains stem/progenitor cells that could contribute to osteogenesis and angiogenesis...
  7. ncbi Prefabrication of vascularized bone graft using a combination of fibroblast growth factor-2 and vascular bundle implantation into a novel interconnected porous calcium hydroxyapatite ceramic
    Tomoyuki Nakasa
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biomed Mater Res A 75:350-5. 2005
    ..This study showed the potential of creating a vascularized bone graft of a predetermined size and shape using a combination of FGF-2 and vascular bundle implantation in the IP-CHA...
  8. ncbi Bone-preserving prosthesis with a single axis for treating osteonecrosis of the femoral head: midterm results for the thrust plate hip prosthesis
    Yuji Yasunaga
    Department of Orthopaedic Surgery, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Sci 8:818-22. 2003
    ..It is an outstanding prosthesis for osteonecrosis of the femoral head of young patients in terms of bone preservation and physiological load transfer...
  9. doi Efficacy of bone marrow mononuclear cells to promote bone regeneration compared with isolated CD34+ cells from the same volume of aspirate
    Shinji Yasuhara
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi Minami ku, Hiroshima, Japan
    Artif Organs 34:594-9. 2010
    ....
  10. ncbi Congenital pseudoarthrosis of the ulna treated with a free vascularized fibular graft
    Osami Suzuki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Plast Reconstr Surg 115:1379-84. 2005
  11. doi Transplantation of meniscus regenerated by tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow
    Takuma Yamasaki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Artif Organs 32:519-24. 2008
    ..At 8 weeks, articular cartilage in the cell-free group was more damaged compared to that in the cell-seeded group or the meniscectomy group...
  12. ncbi Natural course of the minimally symptomatic nonoperated hip in patients with bilateral hip dysplasia treated with contralateral rotational acetabular osteotomy
    Takashi Hisatome
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    J Orthop Sci 10:574-80. 2005
    ..The purpose of this study was to investigate the natural course of the minimally symptomatic nonoperated hip in patients with pre-osteoarthritis or early osteoarthritis in bilaterally dysplastic hips...
  13. pmc Mid-term results of acetabular reconstruction using a Kerboull-type acetabular reinforcement device
    Junji Hori
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1 2 3, Minami Ku, Hiroshima City 734 8551, Japan
    Int Orthop 36:23-6. 2012
    ..The purpose of this study was to investigate the mid-term results of 32 acetabular reconstructions performed using a Kerboull-type acetabular reinforcement device and bone graft between June 1997 and January 2009...
  14. ncbi Meniscal regeneration using tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow
    Takuma Yamasaki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    J Biomed Mater Res A 75:23-30. 2005
    ..From this study, we conclude that a scaffold derived from a normal meniscus seeded with BM-MSCs can form a meniscus approximating a normal meniscus...
  15. doi Rigid bridging of massive femur defect using double vascularized fibula graft with hydroxyapatite
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, Japan
    Arch Orthop Trauma Surg 128:941-4. 2008
    ..Here, a novel surgical procedure for bridging of massive femur defects using double FVFG and hydroxyapatite with autogenous bone grafts to prevent stress fractures is reported...
  16. ncbi Multiple drillings of the acetabular fossa induce early joint remodeling after rotational acetabular osteotomy for hip dysplasia
    Takuma Yamasaki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, Japan
    Arch Orthop Trauma Surg 128:909-13. 2008
    ..The purpose of this study is to evaluate the effect of multiple drillings on early joint remodeling after RAO...
  17. doi Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines
    Jun Fujimori
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Res 29:1707-11. 2011
    ....
  18. ncbi Transplantation of bone marrow mononuclear cells enables simultaneous treatment with osteotomy for osteonecrosis of the bilateral femoral head
    Takuma Yamasaki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    Med Sci Monit 14:CS23-30. 2008
    ..This case report documents the potential of BMMNCs with IP-CHA for bone repair at the lesion of osteonecrosis of the femoral head...
  19. ncbi Three-dimensional computed tomography imaging evidence of regeneration of the semitendinosus tendon harvested for anterior cruciate ligament reconstruction: a comparison with hamstring muscle strength
    Atsuo Nakamae
    Department of Orthopaedic Surgery, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan
    J Comput Assist Tomogr 29:241-5. 2005
    ....
  20. pmc Expression of MicroRNA-146a in osteoarthritis cartilage
    Keiichiro Yamasaki
    Hiroshima University, Hiroshima, Japan
    Arthritis Rheum 60:1035-41. 2009
    ..The objective of this study was to identify the expression pattern of microRNA-146a (miR-146a) in cartilage from patients with osteoarthritis (OA)...
  21. doi Crossover sign after rotational acetabular osteotomy for dysplasia of the hip
    Yuji Yasunaga
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Sci 15:463-9. 2010
    ..This study was performed to evaluate whether the radiographic crossover sign influences the painful femoroacetabular impingement or the radiographic progression of osteoarthritis after rotational acetabular osteotomy (RAO)...
  22. ncbi The cellular origin of cartilage-like tissue after periosteal transplantation of full-thickness articular cartilage defects: an experimental study using transgenic rats expressing green fluorescent protein
    Rikuo Shinomiya
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Acta Orthop 76:920-6. 2005
    ..The objective of this study was to investigate the cellular origin of the regenerated tissue after periosteal transplantation...
  23. ncbi Biomechanical analysis and quantitative analysis of bone scintigraphy on thrust plate hip prosthesis
    Toshihiko Goto
    Department of Orthopaedic Surgery, Hiroshima Prefectual Akitsu Hospital, 4388 Akitsu Ohaza Mitsu, Toyota, 729 2402 Hiroshima, Japan
    Arch Orthop Trauma Surg 124:357-62. 2004
    ....
  24. doi Prevention of osteonecrosis by intravenous administration of human peripheral blood-derived CD34-positive cells in a rat osteonecrosis model
    Hiroshi Terayama
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Japan
    J Tissue Eng Regen Med 5:32-40. 2011
    ..In conclusion, this new therapeutic approach using circulating cell fraction could be a promising cell-based therapy for early-stage osteonecrosis of the hip...
  25. ncbi Flow cytometric discrimination of mesenchymal progenitor cells from bone marrow-adherent cell populations using CD34/44/45(-) and Sca-1(+) markers
    Hiroki Hachisuka
    Department of Orthopedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Sci 12:161-9. 2007
    ..The purposes of this study were to (1) isolate immature mesenchymal stem cells with CD34/44/45 and Sca-1 surface-antigen patterns from BMACs using flow-activated cell sorting and (2) investigate their differentiation potential...
  26. ncbi Intravenously injected neural progenitor cells of transgenic rats can migrate to the injured spinal cord and differentiate into neurons, astrocytes and oligodendrocytes
    Yasushi Fujiwara
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Neurosci Lett 366:287-91. 2004
    ....
  27. ncbi Evaluation of systemic chemotherapy with magnetic liposomal doxorubicin and a dipole external electromagnet
    Hiroo Nobuto
    Department of Orthopedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Int J Cancer 109:627-35. 2004
    ..Such targeted drug delivery for anticancer agents would provide clinical advantages compared to current methods...
  28. ncbi Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities
    Toshihiro Matsuo
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Anticancer Res 25:2951-5. 2005
    ..In addition, the telomere biology of these tumors was investigated...
  29. doi Midterm results of femoral impaction bone grafting with an allograft combined with hydroxyapatite in revision total hip arthroplasty
    Seigo Oshima
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Arthroplasty 27:470-6. 2012
    ..Cortical repair was detected at an average of 7 months postoperatively. Impaction bone grafting with an allograft combined with HA provided favorable results, with bone remodeling and less subsidence...
  30. doi Articular cartilage repair using an intra-articular magnet and synovium-derived cells
    Junji Hori
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Orthop Res 29:531-8. 2011
    ..We demonstrated that articular cartilage defects could be repaired using an intra-articular magnet and M-SDCs. We believe that this system will be useful to repair human articular cartilage defects...
  31. ncbi Relationship between osteochondritis dissecans of the lateral femoral condyle and lateral menisci types
    Masataka Deie
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Pediatr Orthop 26:79-82. 2006
    ..Complete discoid menisci without tears were found in OCDs located in zone 4; incomplete discoid menisci were found in OCDs located in zone 5. The authors found a relationship between the type of OCD and the state of the lateral meniscus...
  32. ncbi Accumulation of magnetically labeled rat mesenchymal stem cells using an external magnetic force, and their potential for bone regeneration
    Toshihiro Sugioka
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biomed Mater Res A 85:597-604. 2008
    ..If this treatment option is established, it will be minimally invasive when compared to conventional treatments...
  33. doi Telomere-maintenance mechanisms in soft-tissue malignant fibrous histiocytomas
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Bone Joint Surg Am 91:928-37. 2009
    ..The present study clarifies the prevalence of the ALT mechanism and examines the prognostic importance of telomere factors in soft-tissue malignant fibrous histiocytomas...
  34. ncbi Efficiency of magnetic liposomal transforming growth factor-beta 1 in the repair of articular cartilage defects in a rabbit model
    Haruyuki Tanaka
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Hiroshima University, Minami Ku, Japan
    J Biomed Mater Res A 73:255-63. 2005
    ....
  35. ncbi Effective repair of a fresh osteochondral defect in the rabbit knee joint by articulated joint distraction following subchondral drilling
    Ryoji Kajiwara
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Res 23:909-15. 2005
    ..We investigated the effects of joint distraction with motion after drilling on a fresh osteochondral defect in the weight bearing area of the rabbit knee joint...
  36. ncbi Extraskeletal osteosarcoma with partial spontaneous regression
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Anticancer Res 29:5197-201. 2009
    ..One of the most unusual phenomena in cancer biology is the spontaneous regression of a tumor. Here, we report on the first case of extraskeletal osteosarcoma characterized by partial spontaneous regression of the primary lesion...
  37. ncbi Telomeres and telomerase in sarcomas
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Anticancer Res 29:3833-6. 2009
    ..We reviewed both the activation of telomere maintenance in a variety of common bone and soft tissue sarcoma subtypes, and the consequences of telomere maintenance mechanisms with respect to the clinical characteristics...
  38. ncbi Bone remodeling of a femoral head after transtrochanteric rotational osteotomy for osteonecrosis associated with slipped capital femoral epiphysis: a case report
    Takuma Yamasaki
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    Arch Orthop Trauma Surg 125:486-9. 2005
    ..This case indicates that a joint-preserving operation such as TRO is capable of promoting bone remodeling in such circumstances...
  39. pmc Correlation between p38 mitogen-activated protein kinase and human telomerase reverse transcriptase in sarcomas
    Toshihiro Matsuo
    Department of Orthopaedic Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center 3 1, Aoyamacho, Kure, Hiroshima, 7370023 Japan
    J Exp Clin Cancer Res 31:5. 2012
    ..The purpose of this study was to analyse the correlation between p38 MAPK and hTERT in sarcoma samples...
  40. ncbi Three-dimensional computed tomography imaging: its applicability in the evaluation of extensor tendons in the hand and wrist
    Toru Sunagawa
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Comput Assist Tomogr 29:94-8. 2005
    ..The purpose of this study was to determine whether 3-dimensional (3D) computed tomography (CT) imaging with volume rendering can accurately evaluate extensor tendons in the hand and wrist...
  41. doi Angiogenic microRNA-210 is present in cells surrounding osteonecrosis
    Keiichiro Yamasaki
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Res 30:1263-70. 2012
    ..This study shows that miR-210 is intensely expressed in ON, and might play a role in ON pathogenesis. The present study provides a solid basis for further functional analyses of miRNAs in ON...
  42. ncbi Injectable magnetic liposomes as a novel carrier of recombinant human BMP-2 for bone formation in a rat bone-defect model
    Toshihiro Matsuo
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biomed Mater Res A 66:747-54. 2003
    ..This injectable carrier for BMP is expected to have many advantages over solid carriers because it can be prepared easily and can be less invasively applied to the injured site at any time after surgery...
  43. ncbi Role of simple cold storage in preventing epiphyseal growth plate impairment after replantation surgery in immature rats
    Toru Sunagawa
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    J Reconstr Microsurg 21:483-9. 2005
    ..The study confirmed experimentally that cold storage of the amputated part may prevent longitudinal bone-growth disturbance after extension of ischemia time...
  44. pmc Stem/progenitor cells in closed suction drainage fluid after hip arthroplasty
    Satoshi Sera
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Acta Orthop 82:217-22. 2011
    ..We analyzed closed suction drainage fluid from hip arthroplasty patients to determine whether any multipotent stem cells were present that could be used as a source of cells for tissue regeneration...
  45. ncbi Progressive collapse of transposed necrotic area after transtrochanteric rotational osteotomy for osteonecrosis of the femoral head induces osteoarthritic change. Mid-term results of transtrochanteric rotational osteotomy for osteonecrosis of the femoral
    Takashi Hisatome
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, 734 8551, Hiroshima, Japan
    Arch Orthop Trauma Surg 124:77-81. 2004
    ..Therefore, for partial osteonecrosis of the femoral head, various types of osteotomies have been developed in an attempt to save the femoral head and maintain the natural function of the hip joint...
  46. ncbi Alternative lengthening of telomeres as a prognostic factor in malignant fibrous histiocytomas of bone
    Toshihiro Matsuo
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Anticancer Res 30:4959-62. 2010
    ..This study was undertaken to analyse the clinical significance of telomere factors in primary tumour samples from patients with MFHs of bone...
  47. ncbi [Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow mononuclear cells]
    Yuji Yasunaga
    Hiroshima University, Graduate School of Biomedical Sciences, Department of Artificial Joints and Biomaterials
    Clin Calcium 17:910-5. 2007
    ..We reported transplantation of bone marrow mononuclear cells for osteonecrosis of the femoral head and short-term results...
  48. ncbi Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells
    Tadahiko Kubo
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Hiroshima 734 8551, Japan
    J Orthop Res 24:1138-44. 2006
    ..These findings suggest that MIN may have a beneficial adjuvant role in the treatment of patients with malignant bone tumors...
  49. ncbi Bone remodeling after impacted cancellous allograft in revision hip arthroplasty based on (99m)Tc-MDP bone scintigraphy
    Takashi Hisatome
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, 734 8551 Hiroshima, Japan
    Arch Orthop Trauma Surg 124:52-5. 2004
    ..Revascularization of the graft was proven with plain radiographs or in some cases, biopsy and autopsy. We have attempted to document the change in appearance of impacted cancellous allograft in the femur over time on scintigraphic scans...
  50. ncbi Effects of transforming growth factor-beta 1 on the early stages of healing of the Achilles tendon in a rat model
    Kenji Kashiwagi
    Department of Orthopaedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Scand J Plast Reconstr Surg Hand Surg 38:193-7. 2004
    ..A dose-dependent increase in the expression of procollagen type I and III mRNA was found one week postoperatively. The failure load and stiffness of the healing tendon were increased by TGF-beta 1 at two and four weeks...
  51. ncbi Allogeneic bone marrow-derived mesenchymal stromal cells promote the regeneration of injured skeletal muscle without differentiation into myofibers
    Koji Natsu
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Tissue Eng 10:1093-112. 2004
    ..Therefore, our results indicated that BMMSCs contributed to the regeneration of skeletal muscle by mechanisms other than fusion to myofibers after differentiation...
  52. ncbi Cervical angina caused by atlantoaxial instability
    Yoshiyuki Ito
    Department of Orthopaedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Spinal Disord Tech 17:462-5. 2004
    ..Cervical angina due to atlantoaxial instability is one of the differential diagnoses of precordialgia...
  53. ncbi Neovascularization and bone regeneration by implantation of autologous bone marrow mononuclear cells
    Takashi Hisatome
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Biomaterials 26:4550-6. 2005
    ..In summary, these findings demonstrate that a combination of BM-MNCs and bFGF gelatin hydrogel enhance the neovascularization and the osteoinductive ability, resulting in bone regeneration...
  54. ncbi Changes of the mineralization pattern in the subchondral bone plate of the glenoid cavity in the shoulder joints of the throwing athletes
    Yu Mochizuki
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Shoulder Elbow Surg 14:616-9. 2005
    ..Our finding of a frequent bicentric density distribution of the shoulder joints of throwing athletes should be useful in any future analysis of the relationship between the DMSB and the bone morphology of the glenoid...
  55. pmc Ten year results of transtrochanteric valgus osteotomy with or without the shelf procedure
    Ryo Mori
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1 2 3, Minami Ku, Hiroshima City, 734 8551, Japan
    Int Orthop 37:599-604. 2013
    ....
  56. pmc Bony impingement depends on the bone morphology of the hip after total hip arthroplasty
    Takeshi Shoji
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Int Orthop 37:1897-903. 2013
    ..The purpose of this study was to evaluate whether the bone morphology of the hip affects the range of motion (ROM) in total hip arthroplasty (THA)...
  57. ncbi Hidden intrapelvic granulomatous lesions associated with total hip arthroplasty: a report of two cases
    Takashi Hisatome
    Department of Orthopaedic Surgery, Hiroshima University Hospital, Hiroshima, Japan
    J Bone Joint Surg Am 85:708-10. 2003
  58. ncbi Second- and third-generation Omniflex modular femoral stem: results 3 to 8 years after surgery
    Kazuhiro Takahashi
    Department of Orthopaedic Surgery, Hiroshima University School of Medicine, Hiroshima, Japan
    J Arthroplasty 18:600-4. 2003
    ..The second- and third- generation Omniflex stems are useful cementless devices resulting in favorable initial biologic fixation and little bone atrophy at mid-term follow-up...
  59. pmc Immunohistochemical expression of promyelocytic leukemia body in soft tissue sarcomas
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Exp Clin Cancer Res 27:73. 2008
    ..This study was undertaken to analyze the clinical significance of PML body expression in primary tumor samples from malignant fibrous histiocytoma (MFH) and liposarcoma patients...
  60. pmc Liposarcoma arising in the foot: a case report
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Case Report Med 2009:630203. 2009
    ..The patient's postoperative course was uneventful without recurrence 5 years after the original operation. The authors review the literature and also report on the low incidence of this tumor arising in the foot...
  61. ncbi Functional diagnosis using multimodal spinal cord evoked potentials in cervical myelopathy
    Nobuhiro Tanaka
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    J Orthop Sci 10:3-7. 2005
    ....
  62. ncbi The HU knot: a new sliding knot for arthroscopic surgery
    Yu Mochizuki
    Division of Clinical Medical Science, Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Arthroscopy 21:1014. 2005
    ..A new sliding knot for arthroscopic surgery, the HU knot, is described. By tensioning the loop strand, the self-locking loop creates a snug knot without sliding backward. The HU knot provides great security...
  63. ncbi Hyperbaric oxygen as an adjuvant for athletes
    Yoshimasa Ishii
    Department of Orthopaedic Surgery, Hiroshima University, Hiroshima, Japan
    Sports Med 35:739-46. 2005
    ..Further research into HBO treatment is required if this therapy is to become more widespread. It should become possible to tailor treatment to an individual's condition in order to use HBO treatment efficiently...
  64. ncbi Intraneural lipoma of the posterior interosseous nerve
    Toshihiro Matsuo
    Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
    J Hand Surg Am 32:1530-2. 2007
    ..This report describes a case with large lipoma arising in the posterior interosseous nerve...
  65. ncbi Bone formation using novel interconnected porous calcium hydroxyapatite ceramic hybridized with cultured marrow stromal stem cells derived from Green rat
    Yoshiyuki Ito
    Department of Orthopedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    J Biomed Mater Res A 69:454-61. 2004
    ..This implantation of the MSCs/IP-CHA composite provides excellent osteoconduction, and is expected to have extensive clinical applications...
  66. ncbi Effects on articular cartilage of subchondral replacement with polymethylmethacrylate and calcium phosphate cement
    Takashi Hisatome
    Department of Orthopedic Surgery, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima, Japan
    J Biomed Mater Res 59:490-8. 2002
    ..Calcium phosphate cement was a reliable subchondral replacement material when the bone defect is adjacent to the articular cartilage...
  67. ncbi Spontaneous decrease in focal osteolysis in the unrevised femur after revision of a contralateral bipolar hemiarthroplasty: a case report
    Kazuhiro Takahashi
    Department of Orthopaedic Surgery, Hiroshima University, Japan
    J Bone Joint Surg Am 85:122-5. 2003
  68. ncbi Arteriovenous malformation of the ring finger. Pre- and postoperative evaluation using three-dimensional computed tomography angiography
    Toru Sunagawa
    Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    J Comput Assist Tomogr 27:820-3. 2003
    ..Three-dimensional computed tomography angiography may be a valuable diagnostic tool even in the evaluation of peripheral vascular lesions...
  69. ncbi Transplanted neuronal progenitor cells in a peripheral nerve gap promote nerve repair
    Takeshi Murakami
    Department of Orthopaedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima City 734 8551, Japan
    Brain Res 974:17-24. 2003
    ....
  70. ncbi Targeted gene delivery to human osteosarcoma cells with magnetic cationic liposomes under a magnetic field
    Ken Hirao
    Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Research Institute for Radiation Biology adn Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Int J Oncol 22:1065-71. 2003
    ..Such a gene delivery system may be applicable under in vivo conditions, and is expected to offer numerous clinical advantages...
  71. pmc Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ): a patient-based evaluation tool for hip-joint disease. The Subcommittee on Hip Disease Evaluation of the Clinical Outcome Committee of the Japanese Orthopaedic Association
    Tadami Matsumoto
    Department of Orthopaedic Surgery, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 0293, Japan
    J Orthop Sci 17:25-38. 2012
    ..However, there is no tool evaluating QOL for Japanese patients with hip-joint disease...
  72. ncbi Corrective valgus osteotomy after free vascularized fibula transfer for the treatment of osteomyelitis at the neck of the femur: case report
    Masakazu Nakamasu
    Department of Orthopedic Surgery, Hiroshima University School of Medicine, Hiroshima, Japan
    J Reconstr Microsurg 20:307-9; discussion 310. 2004
    ..As osteotomy through a transplanted fibula can be safely performed, abduction osteotomy should be considered when coxa vara remains after reconstruction with a free vascularized fibula transfer...
  73. ncbi Acceleration of surgical angiogenesis in necrotic bone with a single injection of fibroblast growth factor-2 (FGF-2)
    Atsuo Nakamae
    Department of Orthopaedic Surgery, Graduate School of Biomedical Science, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Orthop Res 22:509-13. 2004
    ..As FGF-2 is recognized as a potent mitogen for a variety of mesenchymal cells, the combination of vascular bundle implantation and FGF-2 administration may contribute to the treatment of ischemic osteonecrosis...
  74. ncbi Intradural extramedullary mass formation in spinal cord sarcoidosis: case report and literature review
    Takahiko Hamasaki
    Department of Orthopaedic Surgery, Matsuyama Red Cross Hospital, Ehime, Japan
    Spine (Phila Pa 1976) 28:E420-3. 2003
    ..A case of myelopathy caused by intradural extramedullary spinal cord sarcoidosis...