Noriyuki Yanaka

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. pmc RASSF6 expression in adipocytes is down-regulated by interaction with macrophages
    Yohei Sanada
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    PLoS ONE 8:e61931. 2013
  2. ncbi request reprint Mammalian glycerophosphodiester phosphodiesterases
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 71:1811-8. 2007
  3. doi request reprint Vitamin B6 suppresses serine protease inhibitor 3 expression in the colon of rats and in TNF-α-stimulated HT-29 cells
    Noriyuki Yanaka
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Mol Nutr Food Res 55:635-43. 2011
  4. ncbi request reprint Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 73:2809-11. 2009
  5. ncbi request reprint Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, 4 4, Kagamiyama 1 chome, Higashi Hiroshima 739 8528, Japan
    FEBS Lett 581:712-8. 2007
  6. doi request reprint Regulation of colon gene expression by vitamin B6 supplementation
    Keigo Toya
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Mol Nutr Food Res 56:641-52. 2012
  7. ncbi request reprint Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet
    Yoshihito Nogusa
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi, Japan
    Int J Mol Med 17:491-6. 2006
  8. ncbi request reprint Expression of ADP-ribosylation factor-like protein 8B mRNA in the brain is down-regulated in mice fed a high-fat diet
    Tomoaki Haraguchi
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Biosci Biotechnol Biochem 70:1798-802. 2006
  9. ncbi request reprint Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6
    Yoshihito Nogusa
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, 4 4, Kagamiyama 1 chome, Higashi Hiroshima 739 8528, Japan
    Gene 337:173-9. 2004
  10. ncbi request reprint Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse
    Siqin Zhaorigetu
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    J Photochem Photobiol B 71:11-7. 2003

Collaborators

Detail Information

Publications23

  1. pmc RASSF6 expression in adipocytes is down-regulated by interaction with macrophages
    Yohei Sanada
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    PLoS ONE 8:e61931. 2013
    ..These data provide novel insights into the biological significance of interactions between adipocytes and macrophages in adipose tissue during the development of obesity...
  2. ncbi request reprint Mammalian glycerophosphodiester phosphodiesterases
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 71:1811-8. 2007
    ..Thus mammalian GP-PDEs are likely to be important in controlling numerous cellular events, indicating that the GP-PDE superfamily in mammals might be a pharmacological target in the future...
  3. doi request reprint Vitamin B6 suppresses serine protease inhibitor 3 expression in the colon of rats and in TNF-α-stimulated HT-29 cells
    Noriyuki Yanaka
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Mol Nutr Food Res 55:635-43. 2011
    ..Previous reports in the areas of animal studies and, recently epidemiology, have linked anti-tumorigenic and anti-inflammatory effects to dietary vitamin B6. This study investigated the molecular mechanism of these effects of vitamin B6...
  4. ncbi request reprint Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 73:2809-11. 2009
    ..This study indicates that ZPR1-DeltaA (Delta193-246) is a useful tool to provide structural insights into ZPR1 and to investigate the biological significance of the interaction between ZPR1 and eEF1alpha...
  5. ncbi request reprint Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells
    Noriyuki Yanaka
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, 4 4, Kagamiyama 1 chome, Higashi Hiroshima 739 8528, Japan
    FEBS Lett 581:712-8. 2007
    ..Furthermore, a loss-of-function of GDE2 in Neuro2A cells by RNAi blocked RA-induced neurite formation. These results demonstrate that GDE2 expression during neuronal differentiation plays an important role for growing neurites...
  6. doi request reprint Regulation of colon gene expression by vitamin B6 supplementation
    Keigo Toya
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Mol Nutr Food Res 56:641-52. 2012
    ..This study investigated the molecular mechanism of these effects of dietary vitamin B6...
  7. ncbi request reprint Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet
    Yoshihito Nogusa
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi, Japan
    Int J Mol Med 17:491-6. 2006
    ..These results suggest that a high beef tallow diet up-regulates ZPR1 mRNA expression in the brain and might increase the vulnerability to oxidative stress...
  8. ncbi request reprint Expression of ADP-ribosylation factor-like protein 8B mRNA in the brain is down-regulated in mice fed a high-fat diet
    Tomoaki Haraguchi
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Biosci Biotechnol Biochem 70:1798-802. 2006
    ....
  9. ncbi request reprint Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6
    Yoshihito Nogusa
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, 4 4, Kagamiyama 1 chome, Higashi Hiroshima 739 8528, Japan
    Gene 337:173-9. 2004
    ..These results suggest that GP-PDEs are differentially expressed in mouse tissues, and might have distinct roles...
  10. ncbi request reprint Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse
    Siqin Zhaorigetu
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    J Photochem Photobiol B 71:11-7. 2003
    ..The results suggest that sericin possesses photoprotective effect against UVB-induced acute damage and tumor promotion by reducing oxidative stress, COX-2 and cell proliferation in mouse skin...
  11. ncbi request reprint Fish oil feeding up-regulates the expression of 5-aminolevulinate synthase 2 mRNA in rat brain
    Tomoaki Haraguchi
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Japan
    Biosci Biotechnol Biochem 75:1383-5. 2011
    ..ALAS2 promoter activity was found to be regulated by retinoic acid. Our results suggest that fish oil modulates neuronal functions via heme synthesis...
  12. ncbi request reprint Vitamin B6 suppresses NF-kappaB activation in LPS-stimulated mouse macrophages
    Noriyuki Yanaka
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Int J Mol Med 16:1071-5. 2005
    ..These observations suggest that the anti-inflammatory effect of vitamin B6 is mediated by suppression of NF-kappaB activation...
  13. doi request reprint High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c‑Jun pathway
    Peipei Zhang
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Hiroshima 739 8528, Japan
    Mol Med Rep 8:973-8. 2013
    ..Higher expression of IGFBP1 protein by PL was suppressed by cycloheximide. These results suggest that PL may induce the expression of IGFBP1 in hepatoma cells via a mechanism involving the ERK/c‑Jun pathway...
  14. ncbi request reprint A high-fat diet enhances the inhibitory effect of dietary vitamin B6 on colon cell proliferation in mice
    Shun Ichiro Komatsu
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Oncol Rep 14:265-9. 2005
    ..The results suggest that dietary supplemental B6 inhibits colon cell proliferation from the early stage of colon carcinogenesis, and a high-fat diet markedly enhances the inhibitory effect...
  15. ncbi request reprint Short-term feeding of fish oil down-regulates the expression of pyruvate dehydrogenase E1 alpha subunit mRNA in mouse brain
    Yoshihito Nogusa
    Department of Bioresource Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Japan
    Biosci Biotechnol Biochem 69:301-6. 2005
    ..PDHE1alpha mRNA was reduced by supplementation of DHA with a significant decrease in cellular ATP level. These results indicate that fish oil feeding might modulate energy metabolism in the brain...
  16. pmc A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism
    Yuri Okazaki
    Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    J Biol Chem 285:27652-63. 2010
    ....
  17. doi request reprint Vitamin B6 activates p53 and elevates p21 gene expression in cancer cells and the mouse colon
    Peipei Zhang
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Oncol Rep 31:2371-6. 2014
    ..053) in the colons of mice compared to a diet with adequate vitamin B6. Thus, these results suggest vitamin B6 plays a role in increasing p21 gene expression via p53 activation in several cancer cells and the mouse colon. ..
  18. ncbi request reprint Comparative study on the responses of concentrations of B₆-vitamers in several tissues of mice to the dietary level of pyridoxine
    Kabo Masisi
    Graduate School of Biosphere Science, Hiroshima University, Hiroshima, Japan
    J Nutr Sci Vitaminol (Tokyo) 58:446-51. 2012
    ..The results suggest that the responses of concentrations of B₆-vitamers to dietary level of PN greatly differ among several tissues...
  19. ncbi request reprint Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents
    Issei Dairaku
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 74:185-7. 2010
    ..Among the 15 different polyphenols examined, curcumin was found to have an inhibitory effect on the IMPDH activity in both a competitive and uncompetitive manner and to suppress the cellular GTP level in HT-29 colon carcinoma cells...
  20. ncbi request reprint Y-700, a novel inhibitor of xanthine oxidase, suppresses the development of colon aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine-treated mice
    Takao Hashimoto
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima, Japan
    Biosci Biotechnol Biochem 69:209-11. 2005
    ..These results suggest that Y-700 is a useful agent for the prevention of colon tumorigenesis and that xanthine oxidase plays an important role in the development of colon cancer...
  21. doi request reprint Identification and physiological evaluation of the components from citrus fruits as potential drugs for anti-corpulence and anticancer
    Toshifumi Hirata
    Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1 3 1 Kagamiyama, Higashi Hiroshima 739 8526, Japan
    Bioorg Med Chem 17:25-8. 2009
    ..Furthermore, distributions of those bioactive components in the peel of 10 species of Citrus fruits were demonstrated by HPLC analyses...
  22. ncbi request reprint Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-alpha
    Siqin Zhaorigetu
    Graduate School of Biosphere Science, Hiroshima University, Higashi Hiroshima 739 8528, Japan
    Oncol Rep 10:537-43. 2003
    ..The results suggest that sericin possesses protective effect against tumor promotion in mouse skin by suppressing oxidative stress, inflammatory responses and TNF-alpha...
  23. ncbi request reprint Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation
    Noriyuki Yanaka
    Discovery Research Laboratory, Tanabe Seiyaku Co, Ltd, 16 89, Kashima 3 chome, Yodogawa ku, Osaka 532 8505, Japan
    J Biol Chem 278:43595-602. 2003
    ....